PL1687401T3 - Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek - Google Patents

Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek

Info

Publication number
PL1687401T3
PL1687401T3 PL04795276T PL04795276T PL1687401T3 PL 1687401 T3 PL1687401 T3 PL 1687401T3 PL 04795276 T PL04795276 T PL 04795276T PL 04795276 T PL04795276 T PL 04795276T PL 1687401 T3 PL1687401 T3 PL 1687401T3
Authority
PL
Poland
Prior art keywords
proteins
site
amino acids
redox active
active amino
Prior art date
Application number
PL04795276T
Other languages
English (en)
Polish (pl)
Inventor
Lital Alfonta
Peter G Schultz
Zhiwen Zhang
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of PL1687401T3 publication Critical patent/PL1687401T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL04795276T 2003-10-14 2004-10-13 Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek PL1687401T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51153203P 2003-10-14 2003-10-14
PCT/US2004/034089 WO2005038002A2 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins
EP04795276A EP1687401B1 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins

Publications (1)

Publication Number Publication Date
PL1687401T3 true PL1687401T3 (pl) 2013-04-30

Family

ID=34465242

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04795276T PL1687401T3 (pl) 2003-10-14 2004-10-13 Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek

Country Status (14)

Country Link
US (5) US8008041B2 (enExample)
EP (1) EP1687401B1 (enExample)
JP (1) JP5657850B2 (enExample)
CN (2) CN1942579B (enExample)
AU (1) AU2004282577B2 (enExample)
BR (1) BRPI0415308A (enExample)
CA (1) CA2541166A1 (enExample)
DK (1) DK1687401T3 (enExample)
ES (1) ES2396712T3 (enExample)
IL (3) IL174947A (enExample)
MX (1) MXPA06004087A (enExample)
PL (1) PL1687401T3 (enExample)
PT (1) PT1687401E (enExample)
WO (1) WO2005038002A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03009566A (es) * 2001-04-19 2004-12-06 Scripps Research Inst Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales.
KR20050073559A (ko) * 2002-10-16 2005-07-14 더 스크립스 리서치 인스티튜트 당단백질 합성
KR101171397B1 (ko) * 2003-04-17 2012-08-07 더 스크립스 리서치 인스티튜트 진핵 유전자 코드의 확장
CA2527877A1 (en) 2003-06-18 2005-01-13 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
ATE386133T1 (de) * 2003-07-07 2008-03-15 Scripps Research Inst Zusammensetzungen der orthogonalen lysyl-trna und aminoacyl-trna synthetase paaren und ihre verwendungen
US7399619B2 (en) * 2004-05-25 2008-07-15 The Scripps Research Institute Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
US20060110784A1 (en) * 2004-09-22 2006-05-25 The Scripps Research Institute Site-specific labeling of proteins for NMR studies
WO2006110182A2 (en) 2004-10-27 2006-10-19 The Scripps Research Institute Orthogonal translation components for the in vivo incorporation of unnatural amino acids
BRPI0617191A2 (pt) * 2005-10-12 2011-07-19 Scripps Research Inst modificação pós-traducional de polipeptìdeos expressos em fagos
US7776535B2 (en) 2006-02-06 2010-08-17 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
EP1991680B1 (en) 2006-03-09 2013-08-21 The Scripps Research Institute System for the expression of orthogonal translation components in eubacterial host cells
US7790847B2 (en) * 2006-03-16 2010-09-07 The Scripps Research Institute Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine
CA2652894A1 (en) * 2006-05-23 2007-12-06 The Scripps Research Institute Genetically encoded fluorescent coumarin amino acids
WO2008036392A2 (en) 2006-09-21 2008-03-27 The Scripps Research Institute Genetically programmed expression of selectively sulfated proteins in eubacteria
RU2009112104A (ru) 2006-10-18 2010-11-27 Зе Скрипс Ресеч Инститьют (Us) Генетическое встраивание не встречающихся в природе аминокислот в белки клеток млекопитающих
WO2008137452A1 (en) * 2007-05-04 2008-11-13 Kenergy Royalty Company, Llc Implantable high efficiency digital stimulation device
MX2010004464A (es) 2007-10-25 2010-06-07 Scripps Research Inst Incorporacion genetica de 3-aminotirosina a reductasas.
US20090148887A1 (en) * 2007-11-02 2009-06-11 The Scripps Research Institute Genetically encoded boronate amino acid
US9249408B2 (en) * 2007-11-02 2016-02-02 The Scripps Research Institute Directed evolution using proteins comprising unnatural amino acids
BRPI0819929A2 (pt) 2007-12-11 2014-10-14 Scripps Research Inst Expressão de amino ácido não natural em vivo na levedura pichia pastoris metilotrófica
US8318172B2 (en) * 2008-02-08 2012-11-27 The Scripps Research Institute Breaking immunological tolerance with a genetically encoded unnatural amino acid
AU2009333554A1 (en) * 2008-12-09 2011-06-30 Cook Medical Technologies Llc Apparatus and methods for controlled release of tacking devices
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
US8609383B2 (en) 2008-12-10 2013-12-17 The Scripps Research Institute Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
WO2010089741A1 (en) * 2009-02-04 2010-08-12 Ben-Gurion University Of The Negev Research And Development Authority Systems and methods for bio-electricity production
JP6574754B2 (ja) 2013-03-19 2019-09-11 ベイジン シェノゲン ファーマ グループ リミテッド エストロゲン受容体関連疾患を処置するための抗体及び方法
US20150331624A1 (en) * 2014-05-19 2015-11-19 Kabushiki Kaisha Toshiba Host-controlled flash translation layer snapshot
KR101956042B1 (ko) * 2017-07-13 2019-03-08 서강대학교산학협력단 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법
EP3983501B1 (en) 2019-06-17 2025-02-26 Merck Patent GmbH Liquid crystal-based light valve

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879905A (en) * 1996-08-29 1999-03-09 Massachusetts Institute Of Technology In vivo method of initiating protein synthesis with an amino acid other than methionine
MXPA03009566A (es) * 2001-04-19 2004-12-06 Scripps Research Inst Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales.
ATE526414T1 (de) 2002-10-16 2011-10-15 Scripps Research Inst Ortsspezifische einbindung von ketoaminosäuren in proteine
KR20050073559A (ko) 2002-10-16 2005-07-14 더 스크립스 리서치 인스티튜트 당단백질 합성
US7642085B2 (en) 2002-12-22 2010-01-05 The Scripps Research Institute Protein arrays
KR101171397B1 (ko) 2003-04-17 2012-08-07 더 스크립스 리서치 인스티튜트 진핵 유전자 코드의 확장
CA2527877A1 (en) 2003-06-18 2005-01-13 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
ATE386133T1 (de) 2003-07-07 2008-03-15 Scripps Research Inst Zusammensetzungen der orthogonalen lysyl-trna und aminoacyl-trna synthetase paaren und ihre verwendungen
WO2005007870A2 (en) 2003-07-07 2005-01-27 The Scripps Research Institute COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF
US7527943B2 (en) 2003-07-07 2009-05-05 The Scripps Research Institute Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof

Also Published As

Publication number Publication date
US20050227318A1 (en) 2005-10-13
US20120100570A1 (en) 2012-04-26
US20090298124A1 (en) 2009-12-03
WO2005038002A2 (en) 2005-04-28
CN1942579B (zh) 2013-06-26
CN1942579A (zh) 2007-04-04
US8114654B2 (en) 2012-02-14
EP1687401A2 (en) 2006-08-09
IL201705A0 (en) 2011-08-01
JP2007508034A (ja) 2007-04-05
WO2005038002A3 (en) 2006-11-23
JP5657850B2 (ja) 2015-01-21
AU2004282577B2 (en) 2009-10-29
MXPA06004087A (es) 2006-06-27
US8008041B2 (en) 2011-08-30
US9783798B2 (en) 2017-10-10
IL174947A0 (en) 2006-08-20
IL206889A0 (en) 2010-12-30
US7811801B2 (en) 2010-10-12
US20110008782A1 (en) 2011-01-13
DK1687401T3 (da) 2013-02-04
CA2541166A1 (en) 2005-04-28
ES2396712T3 (es) 2013-02-25
EP1687401A4 (en) 2007-08-01
BRPI0415308A (pt) 2006-12-05
US20070009990A1 (en) 2007-01-11
US7494796B2 (en) 2009-02-24
AU2004282577A1 (en) 2005-04-28
IL174947A (en) 2011-11-30
PT1687401E (pt) 2013-02-26
EP1687401B1 (en) 2012-11-21
CN101532046A (zh) 2009-09-16

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