MXPA06004087A - Incorporacion especifica de sitio de amino acidos redox activos en proteinas. - Google Patents
Incorporacion especifica de sitio de amino acidos redox activos en proteinas.Info
- Publication number
- MXPA06004087A MXPA06004087A MXPA06004087A MXPA06004087A MXPA06004087A MX PA06004087 A MXPA06004087 A MX PA06004087A MX PA06004087 A MXPA06004087 A MX PA06004087A MX PA06004087 A MXPA06004087 A MX PA06004087A MX PA06004087 A MXPA06004087 A MX PA06004087A
- Authority
- MX
- Mexico
- Prior art keywords
- trna
- amino acid
- cell
- orthogonal
- amino acids
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- Chemical & Material Sciences (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| PCT/US2004/034089 WO2005038002A2 (en) | 2003-10-14 | 2004-10-13 | Site-specific incorporation of redox active amino acids into proteins |
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| PL (1) | PL1687401T3 (enExample) |
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| MXPA03009566A (es) * | 2001-04-19 | 2004-12-06 | Scripps Research Inst | Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales. |
| KR20050073559A (ko) * | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| KR101171397B1 (ko) * | 2003-04-17 | 2012-08-07 | 더 스크립스 리서치 인스티튜트 | 진핵 유전자 코드의 확장 |
| CA2527877A1 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| ATE386133T1 (de) * | 2003-07-07 | 2008-03-15 | Scripps Research Inst | Zusammensetzungen der orthogonalen lysyl-trna und aminoacyl-trna synthetase paaren und ihre verwendungen |
| US7399619B2 (en) * | 2004-05-25 | 2008-07-15 | The Scripps Research Institute | Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination |
| DE102004031258A1 (de) * | 2004-06-29 | 2006-02-09 | Jennissen, Herbert P., Prof. Dr. | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
| US20060110784A1 (en) * | 2004-09-22 | 2006-05-25 | The Scripps Research Institute | Site-specific labeling of proteins for NMR studies |
| WO2006110182A2 (en) | 2004-10-27 | 2006-10-19 | The Scripps Research Institute | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| BRPI0617191A2 (pt) * | 2005-10-12 | 2011-07-19 | Scripps Research Inst | modificação pós-traducional de polipeptìdeos expressos em fagos |
| US7776535B2 (en) | 2006-02-06 | 2010-08-17 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| EP1991680B1 (en) | 2006-03-09 | 2013-08-21 | The Scripps Research Institute | System for the expression of orthogonal translation components in eubacterial host cells |
| US7790847B2 (en) * | 2006-03-16 | 2010-09-07 | The Scripps Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
| CA2652894A1 (en) * | 2006-05-23 | 2007-12-06 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
| WO2008036392A2 (en) | 2006-09-21 | 2008-03-27 | The Scripps Research Institute | Genetically programmed expression of selectively sulfated proteins in eubacteria |
| RU2009112104A (ru) | 2006-10-18 | 2010-11-27 | Зе Скрипс Ресеч Инститьют (Us) | Генетическое встраивание не встречающихся в природе аминокислот в белки клеток млекопитающих |
| WO2008137452A1 (en) * | 2007-05-04 | 2008-11-13 | Kenergy Royalty Company, Llc | Implantable high efficiency digital stimulation device |
| MX2010004464A (es) | 2007-10-25 | 2010-06-07 | Scripps Research Inst | Incorporacion genetica de 3-aminotirosina a reductasas. |
| US20090148887A1 (en) * | 2007-11-02 | 2009-06-11 | The Scripps Research Institute | Genetically encoded boronate amino acid |
| US9249408B2 (en) * | 2007-11-02 | 2016-02-02 | The Scripps Research Institute | Directed evolution using proteins comprising unnatural amino acids |
| BRPI0819929A2 (pt) | 2007-12-11 | 2014-10-14 | Scripps Research Inst | Expressão de amino ácido não natural em vivo na levedura pichia pastoris metilotrófica |
| US8318172B2 (en) * | 2008-02-08 | 2012-11-27 | The Scripps Research Institute | Breaking immunological tolerance with a genetically encoded unnatural amino acid |
| AU2009333554A1 (en) * | 2008-12-09 | 2011-06-30 | Cook Medical Technologies Llc | Apparatus and methods for controlled release of tacking devices |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| US8609383B2 (en) | 2008-12-10 | 2013-12-17 | The Scripps Research Institute | Production of carrier-peptide conjugates using chemically reactive unnatural amino acids |
| WO2010089741A1 (en) * | 2009-02-04 | 2010-08-12 | Ben-Gurion University Of The Negev Research And Development Authority | Systems and methods for bio-electricity production |
| JP6574754B2 (ja) | 2013-03-19 | 2019-09-11 | ベイジン シェノゲン ファーマ グループ リミテッド | エストロゲン受容体関連疾患を処置するための抗体及び方法 |
| US20150331624A1 (en) * | 2014-05-19 | 2015-11-19 | Kabushiki Kaisha Toshiba | Host-controlled flash translation layer snapshot |
| KR101956042B1 (ko) * | 2017-07-13 | 2019-03-08 | 서강대학교산학협력단 | 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법 |
| EP3983501B1 (en) | 2019-06-17 | 2025-02-26 | Merck Patent GmbH | Liquid crystal-based light valve |
Family Cites Families (10)
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| US5879905A (en) * | 1996-08-29 | 1999-03-09 | Massachusetts Institute Of Technology | In vivo method of initiating protein synthesis with an amino acid other than methionine |
| MXPA03009566A (es) * | 2001-04-19 | 2004-12-06 | Scripps Research Inst | Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales. |
| ATE526414T1 (de) | 2002-10-16 | 2011-10-15 | Scripps Research Inst | Ortsspezifische einbindung von ketoaminosäuren in proteine |
| KR20050073559A (ko) | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| US7642085B2 (en) | 2002-12-22 | 2010-01-05 | The Scripps Research Institute | Protein arrays |
| KR101171397B1 (ko) | 2003-04-17 | 2012-08-07 | 더 스크립스 리서치 인스티튜트 | 진핵 유전자 코드의 확장 |
| CA2527877A1 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| ATE386133T1 (de) | 2003-07-07 | 2008-03-15 | Scripps Research Inst | Zusammensetzungen der orthogonalen lysyl-trna und aminoacyl-trna synthetase paaren und ihre verwendungen |
| WO2005007870A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF |
| US7527943B2 (en) | 2003-07-07 | 2009-05-05 | The Scripps Research Institute | Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof |
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- 2004-10-13 WO PCT/US2004/034089 patent/WO2005038002A2/en not_active Ceased
- 2004-10-13 PL PL04795276T patent/PL1687401T3/pl unknown
- 2004-10-13 MX MXPA06004087A patent/MXPA06004087A/es active IP Right Grant
- 2004-10-13 AU AU2004282577A patent/AU2004282577B2/en not_active Ceased
- 2004-10-13 CA CA002541166A patent/CA2541166A1/en not_active Abandoned
- 2004-10-13 CN CN2004800301376A patent/CN1942579B/zh not_active Expired - Fee Related
- 2004-10-13 CN CN200910004743A patent/CN101532046A/zh active Pending
- 2004-10-13 DK DK04795276.7T patent/DK1687401T3/da active
- 2004-10-13 EP EP04795276A patent/EP1687401B1/en not_active Expired - Lifetime
- 2004-10-13 PT PT47952767T patent/PT1687401E/pt unknown
- 2004-10-13 US US10/575,991 patent/US8008041B2/en not_active Expired - Lifetime
- 2004-10-13 ES ES04795276T patent/ES2396712T3/es not_active Expired - Lifetime
- 2004-10-13 US US10/965,218 patent/US7494796B2/en not_active Expired - Lifetime
- 2004-10-13 JP JP2006535350A patent/JP5657850B2/ja not_active Expired - Fee Related
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- 2006-04-11 IL IL174947A patent/IL174947A/en not_active IP Right Cessation
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- 2008-12-17 US US12/317,034 patent/US7811801B2/en not_active Expired - Lifetime
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- 2009-10-22 IL IL201705A patent/IL201705A0/en unknown
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Also Published As
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| US20050227318A1 (en) | 2005-10-13 |
| US20120100570A1 (en) | 2012-04-26 |
| US20090298124A1 (en) | 2009-12-03 |
| WO2005038002A2 (en) | 2005-04-28 |
| CN1942579B (zh) | 2013-06-26 |
| CN1942579A (zh) | 2007-04-04 |
| US8114654B2 (en) | 2012-02-14 |
| EP1687401A2 (en) | 2006-08-09 |
| IL201705A0 (en) | 2011-08-01 |
| JP2007508034A (ja) | 2007-04-05 |
| WO2005038002A3 (en) | 2006-11-23 |
| JP5657850B2 (ja) | 2015-01-21 |
| AU2004282577B2 (en) | 2009-10-29 |
| US8008041B2 (en) | 2011-08-30 |
| US9783798B2 (en) | 2017-10-10 |
| IL174947A0 (en) | 2006-08-20 |
| IL206889A0 (en) | 2010-12-30 |
| US7811801B2 (en) | 2010-10-12 |
| PL1687401T3 (pl) | 2013-04-30 |
| US20110008782A1 (en) | 2011-01-13 |
| DK1687401T3 (da) | 2013-02-04 |
| CA2541166A1 (en) | 2005-04-28 |
| ES2396712T3 (es) | 2013-02-25 |
| EP1687401A4 (en) | 2007-08-01 |
| BRPI0415308A (pt) | 2006-12-05 |
| US20070009990A1 (en) | 2007-01-11 |
| US7494796B2 (en) | 2009-02-24 |
| AU2004282577A1 (en) | 2005-04-28 |
| IL174947A (en) | 2011-11-30 |
| PT1687401E (pt) | 2013-02-26 |
| EP1687401B1 (en) | 2012-11-21 |
| CN101532046A (zh) | 2009-09-16 |
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