JP5657850B2 - 酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ - Google Patents
酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- Chemical & Material Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| PL (1) | PL1687401T3 (enExample) |
| PT (1) | PT1687401E (enExample) |
| WO (1) | WO2005038002A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12134725B2 (en) | 2019-06-17 | 2024-11-05 | Merck Patent Gmbh | Liquid crystal-based light valve |
Families Citing this family (29)
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| DK2322631T3 (en) * | 2001-04-19 | 2015-01-12 | Scripps Research Inst | Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar |
| ES2333422T3 (es) * | 2002-10-16 | 2010-02-22 | The Scripps Research Institute | Sintesis de glicoproteinas. |
| EP1613735B1 (en) | 2003-04-17 | 2012-01-25 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
| CN102618605B (zh) | 2003-06-18 | 2015-09-02 | 斯克利普斯研究院 | 非天然活性氨基酸遗传密码增加 |
| ATE471385T1 (de) | 2003-07-07 | 2010-07-15 | Scripps Research Inst | Zusammensetzungen aus orthogonalen lysyl-trna- und aminoacyl-trna-synthetasepaaren und deren verwendung |
| JP2008500050A (ja) * | 2004-05-25 | 2008-01-10 | ザ スクリップス リサーチ インスティテュート | 結晶構造決定のための重原子含有非天然アミノ酸の部位特異的蛋白質組込み |
| DE102004031258A1 (de) * | 2004-06-29 | 2006-02-09 | Jennissen, Herbert P., Prof. Dr. | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
| JP2008513806A (ja) * | 2004-09-22 | 2008-05-01 | ザ スクリップス リサーチ インスティテュート | Ｎｍｒ試験のための蛋白質の部位特異的標識 |
| EP1807515A4 (en) | 2004-10-27 | 2008-06-18 | Scripps Research Inst | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| US8367588B2 (en) * | 2005-10-12 | 2013-02-05 | The Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| US7776535B2 (en) * | 2006-02-06 | 2010-08-17 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| US7960141B2 (en) * | 2006-03-09 | 2011-06-14 | The Scripps Research Institute | Systems for the expression of orthogonal translation components in eubacterial host cells |
| AU2007227592B2 (en) | 2006-03-16 | 2011-11-24 | The Scripps Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
| CA2652894A1 (en) * | 2006-05-23 | 2007-12-06 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
| PT2052083E (pt) * | 2006-09-21 | 2014-04-10 | Scripps Research Inst | Expressão geneticamente programada de proteínas seletivamente sulfatadas em eubactérias |
| US9624485B2 (en) | 2006-10-18 | 2017-04-18 | The Scripps Research Institute | Genetic incorporation of unnatural amino acids into proteins in mammalian cells |
| WO2008137452A1 (en) * | 2007-05-04 | 2008-11-13 | Kenergy Royalty Company, Llc | Implantable high efficiency digital stimulation device |
| MX2010004464A (es) | 2007-10-25 | 2010-06-07 | Scripps Research Inst | Incorporacion genetica de 3-aminotirosina a reductasas. |
| EP2220218A4 (en) * | 2007-11-02 | 2010-12-08 | Scripps Research Inst | GENETICALLY ENCODED BORONATE AMINO ACID |
| US9249408B2 (en) * | 2007-11-02 | 2016-02-02 | The Scripps Research Institute | Directed evolution using proteins comprising unnatural amino acids |
| KR20100105846A (ko) * | 2007-12-11 | 2010-09-30 | 더 스크립스 리서치 인스티튜트 | 메틸영양요구성 효모 피키아 파스토리스에서의 생체 내 비천연 아미노산 발현 |
| KR20100125290A (ko) * | 2008-02-08 | 2010-11-30 | 더 스크립스 리서치 인스티튜트 | 유전적으로 코딩된 비천연 아미노산에 의한 면역 내성의 파괴 |
| WO2010077608A1 (en) * | 2008-12-09 | 2010-07-08 | Wilson-Cook Medical Inc. | Apparatus and methods for controlled release of tacking devices |
| JP5959201B2 (ja) | 2008-12-10 | 2016-08-02 | ザ スクリプス リサーチ インスティテュート | 化学的に反応性の非天然アミノ酸を使用するキャリア−ペプチド接合体の製造 |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| EP2394323B1 (en) * | 2009-02-04 | 2017-05-24 | Ben-gurion University Of The Negev Research And Development Authority | Systems and methods for bio-electricity production |
| WO2014146575A1 (en) | 2013-03-19 | 2014-09-25 | Beijing Shenogen Pharma Group Ltd. | Antibodies and methods for treating estrogen receptor-associated diseases |
| US20150331624A1 (en) * | 2014-05-19 | 2015-11-19 | Kabushiki Kaisha Toshiba | Host-controlled flash translation layer snapshot |
| KR101956042B1 (ko) * | 2017-07-13 | 2019-03-08 | 서강대학교산학협력단 | 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법 |
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| US5879905A (en) * | 1996-08-29 | 1999-03-09 | Massachusetts Institute Of Technology | In vivo method of initiating protein synthesis with an amino acid other than methionine |
| DK2322631T3 (en) * | 2001-04-19 | 2015-01-12 | Scripps Research Inst | Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar |
| DK1578949T3 (da) | 2002-10-16 | 2009-07-27 | Scripps Research Inst | Stedspecifik optagelse af keto-aminnosyrer hos proteiner |
| ES2333422T3 (es) | 2002-10-16 | 2010-02-22 | The Scripps Research Institute | Sintesis de glicoproteinas. |
| MXPA05006836A (es) | 2002-12-22 | 2005-08-16 | Scripps Research Inst | Colecciones ordenadas de proteinas. |
| EP1613735B1 (en) | 2003-04-17 | 2012-01-25 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
| CN102618605B (zh) | 2003-06-18 | 2015-09-02 | 斯克利普斯研究院 | 非天然活性氨基酸遗传密码增加 |
| US20060160175A1 (en) | 2003-07-07 | 2006-07-20 | The Scripps Research Institute | Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| ATE471385T1 (de) | 2003-07-07 | 2010-07-15 | Scripps Research Inst | Zusammensetzungen aus orthogonalen lysyl-trna- und aminoacyl-trna-synthetasepaaren und deren verwendung |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
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- 2004-10-13 MX MXPA06004087A patent/MXPA06004087A/es active IP Right Grant
- 2004-10-13 EP EP04795276A patent/EP1687401B1/en not_active Expired - Lifetime
- 2004-10-13 US US10/965,218 patent/US7494796B2/en not_active Expired - Lifetime
- 2004-10-13 AU AU2004282577A patent/AU2004282577B2/en not_active Ceased
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- 2004-10-13 PL PL04795276T patent/PL1687401T3/pl unknown
- 2004-10-13 BR BRPI0415308-1A patent/BRPI0415308A/pt not_active IP Right Cessation
- 2004-10-13 WO PCT/US2004/034089 patent/WO2005038002A2/en not_active Ceased
- 2004-10-13 DK DK04795276.7T patent/DK1687401T3/da active
- 2004-10-13 CN CN200910004743A patent/CN101532046A/zh active Pending
- 2004-10-13 JP JP2006535350A patent/JP5657850B2/ja not_active Expired - Fee Related
- 2004-10-13 US US10/575,991 patent/US8008041B2/en not_active Expired - Lifetime
- 2004-10-13 CN CN2004800301376A patent/CN1942579B/zh not_active Expired - Fee Related
- 2004-10-13 PT PT47952767T patent/PT1687401E/pt unknown
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2006
- 2006-04-11 IL IL174947A patent/IL174947A/en not_active IP Right Cessation
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2008
- 2008-12-17 US US12/317,034 patent/US7811801B2/en not_active Expired - Lifetime
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2009
- 2009-10-22 IL IL201705A patent/IL201705A0/en unknown
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- 2010-07-08 IL IL206889A patent/IL206889A0/en unknown
- 2010-08-20 US US12/806,751 patent/US8114654B2/en not_active Expired - Lifetime
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- 2012-01-05 US US13/344,436 patent/US9783798B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12134725B2 (en) | 2019-06-17 | 2024-11-05 | Merck Patent Gmbh | Liquid crystal-based light valve |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2541166A1 (en) | 2005-04-28 |
| IL201705A0 (en) | 2011-08-01 |
| JP2007508034A (ja) | 2007-04-05 |
| PT1687401E (pt) | 2013-02-26 |
| US20120100570A1 (en) | 2012-04-26 |
| EP1687401A4 (en) | 2007-08-01 |
| IL174947A0 (en) | 2006-08-20 |
| EP1687401A2 (en) | 2006-08-09 |
| AU2004282577B2 (en) | 2009-10-29 |
| CN1942579A (zh) | 2007-04-04 |
| US9783798B2 (en) | 2017-10-10 |
| WO2005038002A2 (en) | 2005-04-28 |
| US20110008782A1 (en) | 2011-01-13 |
| DK1687401T3 (da) | 2013-02-04 |
| CN101532046A (zh) | 2009-09-16 |
| ES2396712T3 (es) | 2013-02-25 |
| MXPA06004087A (es) | 2006-06-27 |
| WO2005038002A3 (en) | 2006-11-23 |
| PL1687401T3 (pl) | 2013-04-30 |
| CN1942579B (zh) | 2013-06-26 |
| US7811801B2 (en) | 2010-10-12 |
| US20070009990A1 (en) | 2007-01-11 |
| US20050227318A1 (en) | 2005-10-13 |
| IL206889A0 (en) | 2010-12-30 |
| US7494796B2 (en) | 2009-02-24 |
| IL174947A (en) | 2011-11-30 |
| US8008041B2 (en) | 2011-08-30 |
| EP1687401B1 (en) | 2012-11-21 |
| US20090298124A1 (en) | 2009-12-03 |
| AU2004282577A1 (en) | 2005-04-28 |
| BRPI0415308A (pt) | 2006-12-05 |
| US8114654B2 (en) | 2012-02-14 |
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