JP5657850B2 - 酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ - Google Patents
酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ Download PDFInfo
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- 239000001226 triphosphate Substances 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| US51153203P | 2003-10-14 | 2003-10-14 | |
| US60/511,532 | 2003-10-14 | ||
| PCT/US2004/034089 WO2005038002A2 (en) | 2003-10-14 | 2004-10-13 | Site-specific incorporation of redox active amino acids into proteins |
Publications (3)
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| JP2007508034A JP2007508034A (ja) | 2007-04-05 |
| JP2007508034A5 JP2007508034A5 (enExample) | 2007-12-27 |
| JP5657850B2 true JP5657850B2 (ja) | 2015-01-21 |
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| CN (2) | CN101532046A (enExample) |
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| BR (1) | BRPI0415308A (enExample) |
| CA (1) | CA2541166A1 (enExample) |
| DK (1) | DK1687401T3 (enExample) |
| ES (1) | ES2396712T3 (enExample) |
| IL (3) | IL174947A (enExample) |
| MX (1) | MXPA06004087A (enExample) |
| PL (1) | PL1687401T3 (enExample) |
| PT (1) | PT1687401E (enExample) |
| WO (1) | WO2005038002A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12134725B2 (en) | 2019-06-17 | 2024-11-05 | Merck Patent Gmbh | Liquid crystal-based light valve |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2464532T3 (es) * | 2001-04-19 | 2014-06-03 | The Scripps Research Institute | Métodos y composiciones para la producción de pares ortogonales de ARNt-aminoacil-ARNt sintetasa |
| EP1558747B1 (en) * | 2002-10-16 | 2009-10-14 | The Scripps Research Institute | Glycoprotein synthesis |
| JP5642916B2 (ja) * | 2003-04-17 | 2014-12-17 | ザ スクリプス リサーチ インスティテュート | 真核遺伝コードの拡張 |
| JP5275566B2 (ja) | 2003-06-18 | 2013-08-28 | ザ スクリプス リサーチ インスティチュート | 反応性非天然アミノ酸遺伝コード付加 |
| WO2005019415A2 (en) | 2003-07-07 | 2005-03-03 | The Scripps Research Institute | Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| CA2567624A1 (en) * | 2004-05-25 | 2005-12-08 | The Scripps Research Institute | Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for crystal structure determination |
| DE102004031258A1 (de) * | 2004-06-29 | 2006-02-09 | Jennissen, Herbert P., Prof. Dr. | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
| EP1794312A4 (en) * | 2004-09-22 | 2009-08-12 | Scripps Research Inst | LOCAL LABELING OF PROTEINS FOR NMR STUDIES |
| MX2007004892A (es) | 2004-10-27 | 2007-08-16 | Scripps Research Inst | Componentes de traduccion ortogonales para la incorporacion in vivo de aminoacidos no naturales. |
| CA2624290A1 (en) * | 2005-10-12 | 2007-04-26 | Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| WO2007092475A2 (en) * | 2006-02-06 | 2007-08-16 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| MX2008011470A (es) | 2006-03-09 | 2008-09-24 | Scripps Research Inst | Sistemas para la expresion de componentes de traduccion ortogonales en celulas huesped eubacterianas. |
| US7790847B2 (en) * | 2006-03-16 | 2010-09-07 | The Scripps Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
| US7807411B2 (en) * | 2006-05-23 | 2010-10-05 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
| US8114627B2 (en) * | 2006-09-21 | 2012-02-14 | The Scripps Research Institute | Genetically programmed expression of selectively sulfated proteins in eubacteria |
| CN101535338A (zh) | 2006-10-18 | 2009-09-16 | 斯克利普斯研究院 | 在哺乳动物细胞中将非天然氨基酸遗传掺入蛋白质 |
| WO2008137452A1 (en) * | 2007-05-04 | 2008-11-13 | Kenergy Royalty Company, Llc | Implantable high efficiency digital stimulation device |
| EP2217707B1 (en) * | 2007-10-25 | 2014-10-15 | The Scripps Research Institute | Genetic incorporation of 3-aminotyrosine into reductases |
| EP2220218A4 (en) * | 2007-11-02 | 2010-12-08 | Scripps Research Inst | GENETICALLY ENCODED BORONATE AMINO ACID |
| US9150849B2 (en) | 2007-11-02 | 2015-10-06 | The Scripps Research Institute | Directed evolution using proteins comprising unnatural amino acids |
| JP2011527886A (ja) | 2007-12-11 | 2011-11-10 | ザ スクリプス リサーチ インスティチュート | メタノール資化性酵母ピキア・パストリスにおけるインビボ非天然アミノ酸発現 |
| CA2712080A1 (en) * | 2008-02-08 | 2009-08-13 | The Scripps Research Institute | Breaking immunological tolerance with a genetically encoded unnatural amino acid |
| WO2010077608A1 (en) * | 2008-12-09 | 2010-07-08 | Wilson-Cook Medical Inc. | Apparatus and methods for controlled release of tacking devices |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| EP2370473B1 (en) | 2008-12-10 | 2016-05-11 | The Scripps Research Institute | Production of carrier-peptide conjugates using chemically reactive unnatural amino acids |
| EP2394323B1 (en) * | 2009-02-04 | 2017-05-24 | Ben-gurion University Of The Negev Research And Development Authority | Systems and methods for bio-electricity production |
| US10233249B2 (en) | 2013-03-19 | 2019-03-19 | Beijing Shenogen Pharma Group Ltd. | Antibodies and methods for treating estrogen receptor-associated diseases |
| US20150331624A1 (en) * | 2014-05-19 | 2015-11-19 | Kabushiki Kaisha Toshiba | Host-controlled flash translation layer snapshot |
| KR101956042B1 (ko) * | 2017-07-13 | 2019-03-08 | 서강대학교산학협력단 | 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법 |
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| US5879905A (en) * | 1996-08-29 | 1999-03-09 | Massachusetts Institute Of Technology | In vivo method of initiating protein synthesis with an amino acid other than methionine |
| ES2464532T3 (es) | 2001-04-19 | 2014-06-03 | The Scripps Research Institute | Métodos y composiciones para la producción de pares ortogonales de ARNt-aminoacil-ARNt sintetasa |
| MXPA05003983A (es) | 2002-10-16 | 2005-06-22 | Scripps Research Inst | Incorporacion en sitio especifico de cetoaminoacidos en proteinas. |
| EP1558747B1 (en) | 2002-10-16 | 2009-10-14 | The Scripps Research Institute | Glycoprotein synthesis |
| EP1583816A4 (en) | 2002-12-22 | 2007-06-13 | Scripps Research Inst | PROTEIN ARRAYS |
| JP5642916B2 (ja) | 2003-04-17 | 2014-12-17 | ザ スクリプス リサーチ インスティテュート | 真核遺伝コードの拡張 |
| JP5275566B2 (ja) | 2003-06-18 | 2013-08-28 | ザ スクリプス リサーチ インスティチュート | 反応性非天然アミノ酸遺伝コード付加 |
| WO2005019415A2 (en) | 2003-07-07 | 2005-03-03 | The Scripps Research Institute | Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| EP1704242A4 (en) | 2003-07-07 | 2008-06-18 | Scripps Research Inst | COMPOSITIONS WITH PAIRS OF ORTHOGONAL LEUCYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
-
2004
- 2004-10-13 CN CN200910004743A patent/CN101532046A/zh active Pending
- 2004-10-13 CN CN2004800301376A patent/CN1942579B/zh not_active Expired - Fee Related
- 2004-10-13 MX MXPA06004087A patent/MXPA06004087A/es active IP Right Grant
- 2004-10-13 WO PCT/US2004/034089 patent/WO2005038002A2/en not_active Ceased
- 2004-10-13 ES ES04795276T patent/ES2396712T3/es not_active Expired - Lifetime
- 2004-10-13 EP EP04795276A patent/EP1687401B1/en not_active Expired - Lifetime
- 2004-10-13 US US10/575,991 patent/US8008041B2/en not_active Expired - Lifetime
- 2004-10-13 DK DK04795276.7T patent/DK1687401T3/da active
- 2004-10-13 US US10/965,218 patent/US7494796B2/en not_active Expired - Lifetime
- 2004-10-13 JP JP2006535350A patent/JP5657850B2/ja not_active Expired - Fee Related
- 2004-10-13 PT PT47952767T patent/PT1687401E/pt unknown
- 2004-10-13 PL PL04795276T patent/PL1687401T3/pl unknown
- 2004-10-13 AU AU2004282577A patent/AU2004282577B2/en not_active Ceased
- 2004-10-13 CA CA002541166A patent/CA2541166A1/en not_active Abandoned
- 2004-10-13 BR BRPI0415308-1A patent/BRPI0415308A/pt not_active IP Right Cessation
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2006
- 2006-04-11 IL IL174947A patent/IL174947A/en not_active IP Right Cessation
-
2008
- 2008-12-17 US US12/317,034 patent/US7811801B2/en not_active Expired - Lifetime
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2009
- 2009-10-22 IL IL201705A patent/IL201705A0/en unknown
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2010
- 2010-07-08 IL IL206889A patent/IL206889A0/en unknown
- 2010-08-20 US US12/806,751 patent/US8114654B2/en not_active Expired - Lifetime
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2012
- 2012-01-05 US US13/344,436 patent/US9783798B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12134725B2 (en) | 2019-06-17 | 2024-11-05 | Merck Patent Gmbh | Liquid crystal-based light valve |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005038002A2 (en) | 2005-04-28 |
| ES2396712T3 (es) | 2013-02-25 |
| IL201705A0 (en) | 2011-08-01 |
| US20120100570A1 (en) | 2012-04-26 |
| US8008041B2 (en) | 2011-08-30 |
| US8114654B2 (en) | 2012-02-14 |
| US20110008782A1 (en) | 2011-01-13 |
| MXPA06004087A (es) | 2006-06-27 |
| WO2005038002A3 (en) | 2006-11-23 |
| US7494796B2 (en) | 2009-02-24 |
| AU2004282577A1 (en) | 2005-04-28 |
| US20070009990A1 (en) | 2007-01-11 |
| BRPI0415308A (pt) | 2006-12-05 |
| CN1942579B (zh) | 2013-06-26 |
| JP2007508034A (ja) | 2007-04-05 |
| AU2004282577B2 (en) | 2009-10-29 |
| US20050227318A1 (en) | 2005-10-13 |
| US9783798B2 (en) | 2017-10-10 |
| CN101532046A (zh) | 2009-09-16 |
| IL206889A0 (en) | 2010-12-30 |
| US7811801B2 (en) | 2010-10-12 |
| PT1687401E (pt) | 2013-02-26 |
| DK1687401T3 (da) | 2013-02-04 |
| CN1942579A (zh) | 2007-04-04 |
| IL174947A0 (en) | 2006-08-20 |
| US20090298124A1 (en) | 2009-12-03 |
| IL174947A (en) | 2011-11-30 |
| EP1687401B1 (en) | 2012-11-21 |
| CA2541166A1 (en) | 2005-04-28 |
| EP1687401A2 (en) | 2006-08-09 |
| PL1687401T3 (pl) | 2013-04-30 |
| EP1687401A4 (en) | 2007-08-01 |
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