CA2541166A1 - Site-specific incorporation of redox active amino acids into proteins - Google Patents
Site-specific incorporation of redox active amino acids into proteins Download PDFInfo
- Publication number
- CA2541166A1 CA2541166A1 CA002541166A CA2541166A CA2541166A1 CA 2541166 A1 CA2541166 A1 CA 2541166A1 CA 002541166 A CA002541166 A CA 002541166A CA 2541166 A CA2541166 A CA 2541166A CA 2541166 A1 CA2541166 A1 CA 2541166A1
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- trna
- amino acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51153203P | 2003-10-14 | 2003-10-14 | |
| US60/511,532 | 2003-10-14 | ||
| PCT/US2004/034089 WO2005038002A2 (en) | 2003-10-14 | 2004-10-13 | Site-specific incorporation of redox active amino acids into proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2541166A1 true CA2541166A1 (en) | 2005-04-28 |
Family
ID=34465242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002541166A Abandoned CA2541166A1 (en) | 2003-10-14 | 2004-10-13 | Site-specific incorporation of redox active amino acids into proteins |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US8008041B2 (enExample) |
| EP (1) | EP1687401B1 (enExample) |
| JP (1) | JP5657850B2 (enExample) |
| CN (2) | CN1942579B (enExample) |
| AU (1) | AU2004282577B2 (enExample) |
| BR (1) | BRPI0415308A (enExample) |
| CA (1) | CA2541166A1 (enExample) |
| DK (1) | DK1687401T3 (enExample) |
| ES (1) | ES2396712T3 (enExample) |
| IL (3) | IL174947A (enExample) |
| MX (1) | MXPA06004087A (enExample) |
| PL (1) | PL1687401T3 (enExample) |
| PT (1) | PT1687401E (enExample) |
| WO (1) | WO2005038002A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1490483B1 (en) * | 2001-04-19 | 2015-06-03 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| KR20050073559A (ko) * | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| CN103289960B (zh) | 2003-04-17 | 2017-04-26 | 斯克利普斯研究院 | 扩展真核生物遗传密码 |
| WO2005003294A2 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| DE602004011789T2 (de) * | 2003-07-07 | 2009-02-12 | The Scripps Research Institute, La Jolla | Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen |
| AU2005248392A1 (en) * | 2004-05-25 | 2005-12-08 | Irm, Llc | Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for crystal structure determination |
| DE102004031258A1 (de) * | 2004-06-29 | 2006-02-09 | Jennissen, Herbert P., Prof. Dr. | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
| JP2008513806A (ja) * | 2004-09-22 | 2008-05-01 | ザ スクリップス リサーチ インスティテュート | Ｎｍｒ試験のための蛋白質の部位特異的標識 |
| AU2005330514B2 (en) * | 2004-10-27 | 2011-05-12 | The Scripps Research Institute | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| CA2624290A1 (en) * | 2005-10-12 | 2007-04-26 | Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| WO2007092475A2 (en) * | 2006-02-06 | 2007-08-16 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| CA2638763A1 (en) * | 2006-03-09 | 2007-09-13 | The Scripps Research Institute | System for the expression of orthogonal translation components in eubacterial host cells |
| JP5249194B2 (ja) * | 2006-03-16 | 2013-07-31 | ザ スクリプス リサーチ インスティチュート | 非天然アミノ酸フェニルセレノシステインを含有するタンパク質の遺伝的にプログラムされた発現 |
| BRPI0711811A2 (pt) * | 2006-05-23 | 2011-12-06 | Scripps Research Inst | aminoácidos de cumarina fluorescente geneticamente codificados |
| CA2663052A1 (en) * | 2006-09-21 | 2008-03-27 | The Scripps Research Institute | Genetically programmed expression of selectively sulfated proteins in eubacteria |
| US20080166766A1 (en) | 2006-10-18 | 2008-07-10 | The Scripps Research Institute | Genetic incorporation of unnatural amino acids into proteins in mammalian cells |
| WO2008137452A1 (en) * | 2007-05-04 | 2008-11-13 | Kenergy Royalty Company, Llc | Implantable high efficiency digital stimulation device |
| KR20100088618A (ko) * | 2007-10-25 | 2010-08-09 | 더 스크립스 리서치 인스티튜트 | 리덕타제 내로의 3-아미노티로신의 유전적 도입 |
| BRPI0819092A2 (pt) | 2007-11-02 | 2014-10-14 | Scripps Research Inst | Evolução direcionada usando proteínas que compreendem aminoácidos não naturais. |
| US20090148887A1 (en) * | 2007-11-02 | 2009-06-11 | The Scripps Research Institute | Genetically encoded boronate amino acid |
| CN105647824A (zh) * | 2007-12-11 | 2016-06-08 | 斯克利普斯研究院 | 甲基营养酵母菌巴斯德毕赤酵母中的体内非天然氨基酸表达 |
| KR20100125290A (ko) * | 2008-02-08 | 2010-11-30 | 더 스크립스 리서치 인스티튜트 | 유전적으로 코딩된 비천연 아미노산에 의한 면역 내성의 파괴 |
| JP2012511403A (ja) * | 2008-12-09 | 2012-05-24 | クック メディカル テクノロジーズ エルエルシー | 鋲留め器具の制御放出のための装置と方法 |
| US8637306B2 (en) * | 2008-12-10 | 2014-01-28 | The Scripps Research Institute | Production of carrier-peptide conjugates using chemically reactive unnatural amino acids |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| US9017978B2 (en) * | 2009-02-04 | 2015-04-28 | Bengurion University Of The Negev Research And Development Authority | Systems and method for bio-electricity production |
| JP6574754B2 (ja) | 2013-03-19 | 2019-09-11 | ベイジン シェノゲン ファーマ グループ リミテッド | エストロゲン受容体関連疾患を処置するための抗体及び方法 |
| US20150331624A1 (en) * | 2014-05-19 | 2015-11-19 | Kabushiki Kaisha Toshiba | Host-controlled flash translation layer snapshot |
| KR101956042B1 (ko) * | 2017-07-13 | 2019-03-08 | 서강대학교산학협력단 | 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법 |
| US12134725B2 (en) | 2019-06-17 | 2024-11-05 | Merck Patent Gmbh | Liquid crystal-based light valve |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879905A (en) * | 1996-08-29 | 1999-03-09 | Massachusetts Institute Of Technology | In vivo method of initiating protein synthesis with an amino acid other than methionine |
| EP1490483B1 (en) * | 2001-04-19 | 2015-06-03 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| DK1578949T3 (da) | 2002-10-16 | 2009-07-27 | Scripps Research Inst | Stedspecifik optagelse af keto-aminnosyrer hos proteiner |
| KR20050073559A (ko) | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| EP1583816A4 (en) | 2002-12-22 | 2007-06-13 | Scripps Research Inst | PROTEIN ARRAYS |
| CN103289960B (zh) | 2003-04-17 | 2017-04-26 | 斯克利普斯研究院 | 扩展真核生物遗传密码 |
| WO2005003294A2 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| WO2005007870A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF |
| DE602004011789T2 (de) | 2003-07-07 | 2009-02-12 | The Scripps Research Institute, La Jolla | Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
-
2004
- 2004-10-13 WO PCT/US2004/034089 patent/WO2005038002A2/en not_active Ceased
- 2004-10-13 CA CA002541166A patent/CA2541166A1/en not_active Abandoned
- 2004-10-13 CN CN2004800301376A patent/CN1942579B/zh not_active Expired - Fee Related
- 2004-10-13 BR BRPI0415308-1A patent/BRPI0415308A/pt not_active IP Right Cessation
- 2004-10-13 MX MXPA06004087A patent/MXPA06004087A/es active IP Right Grant
- 2004-10-13 JP JP2006535350A patent/JP5657850B2/ja not_active Expired - Fee Related
- 2004-10-13 ES ES04795276T patent/ES2396712T3/es not_active Expired - Lifetime
- 2004-10-13 US US10/575,991 patent/US8008041B2/en not_active Expired - Lifetime
- 2004-10-13 CN CN200910004743A patent/CN101532046A/zh active Pending
- 2004-10-13 PT PT47952767T patent/PT1687401E/pt unknown
- 2004-10-13 AU AU2004282577A patent/AU2004282577B2/en not_active Ceased
- 2004-10-13 PL PL04795276T patent/PL1687401T3/pl unknown
- 2004-10-13 DK DK04795276.7T patent/DK1687401T3/da active
- 2004-10-13 US US10/965,218 patent/US7494796B2/en not_active Expired - Lifetime
- 2004-10-13 EP EP04795276A patent/EP1687401B1/en not_active Expired - Lifetime
-
2006
- 2006-04-11 IL IL174947A patent/IL174947A/en not_active IP Right Cessation
-
2008
- 2008-12-17 US US12/317,034 patent/US7811801B2/en not_active Expired - Lifetime
-
2009
- 2009-10-22 IL IL201705A patent/IL201705A0/en unknown
-
2010
- 2010-07-08 IL IL206889A patent/IL206889A0/en unknown
- 2010-08-20 US US12/806,751 patent/US8114654B2/en not_active Expired - Lifetime
-
2012
- 2012-01-05 US US13/344,436 patent/US9783798B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL201705A0 (en) | 2011-08-01 |
| EP1687401A4 (en) | 2007-08-01 |
| US7811801B2 (en) | 2010-10-12 |
| IL206889A0 (en) | 2010-12-30 |
| US8114654B2 (en) | 2012-02-14 |
| IL174947A0 (en) | 2006-08-20 |
| US20110008782A1 (en) | 2011-01-13 |
| CN1942579B (zh) | 2013-06-26 |
| EP1687401A2 (en) | 2006-08-09 |
| AU2004282577B2 (en) | 2009-10-29 |
| EP1687401B1 (en) | 2012-11-21 |
| PL1687401T3 (pl) | 2013-04-30 |
| US20090298124A1 (en) | 2009-12-03 |
| MXPA06004087A (es) | 2006-06-27 |
| JP5657850B2 (ja) | 2015-01-21 |
| DK1687401T3 (da) | 2013-02-04 |
| BRPI0415308A (pt) | 2006-12-05 |
| US20050227318A1 (en) | 2005-10-13 |
| WO2005038002A2 (en) | 2005-04-28 |
| WO2005038002A3 (en) | 2006-11-23 |
| AU2004282577A1 (en) | 2005-04-28 |
| US7494796B2 (en) | 2009-02-24 |
| IL174947A (en) | 2011-11-30 |
| US9783798B2 (en) | 2017-10-10 |
| CN101532046A (zh) | 2009-09-16 |
| ES2396712T3 (es) | 2013-02-25 |
| CN1942579A (zh) | 2007-04-04 |
| US20070009990A1 (en) | 2007-01-11 |
| US8008041B2 (en) | 2011-08-30 |
| JP2007508034A (ja) | 2007-04-05 |
| US20120100570A1 (en) | 2012-04-26 |
| PT1687401E (pt) | 2013-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20140821 |