DK1687401T3 - Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener - Google Patents

Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener

Info

Publication number
DK1687401T3
DK1687401T3 DK04795276.7T DK04795276T DK1687401T3 DK 1687401 T3 DK1687401 T3 DK 1687401T3 DK 04795276 T DK04795276 T DK 04795276T DK 1687401 T3 DK1687401 T3 DK 1687401T3
Authority
DK
Denmark
Prior art keywords
protiens
redox
site
amino acids
active amino
Prior art date
Application number
DK04795276.7T
Other languages
Danish (da)
English (en)
Inventor
Lital Alfonta
Peter G Schultz
Zhiwen Zhang
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK1687401T3 publication Critical patent/DK1687401T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK04795276.7T 2003-10-14 2004-10-13 Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener DK1687401T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51153203P 2003-10-14 2003-10-14
PCT/US2004/034089 WO2005038002A2 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins

Publications (1)

Publication Number Publication Date
DK1687401T3 true DK1687401T3 (da) 2013-02-04

Family

ID=34465242

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04795276.7T DK1687401T3 (da) 2003-10-14 2004-10-13 Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener

Country Status (14)

Country Link
US (5) US8008041B2 (enExample)
EP (1) EP1687401B1 (enExample)
JP (1) JP5657850B2 (enExample)
CN (2) CN101532046A (enExample)
AU (1) AU2004282577B2 (enExample)
BR (1) BRPI0415308A (enExample)
CA (1) CA2541166A1 (enExample)
DK (1) DK1687401T3 (enExample)
ES (1) ES2396712T3 (enExample)
IL (3) IL174947A (enExample)
MX (1) MXPA06004087A (enExample)
PL (1) PL1687401T3 (enExample)
PT (1) PT1687401E (enExample)
WO (1) WO2005038002A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2322631T3 (en) * 2001-04-19 2015-01-12 Scripps Research Inst Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar
CA2500653A1 (en) * 2002-10-16 2004-04-29 The Scripps Research Institute Glycoprotein synthesis
KR101171397B1 (ko) 2003-04-17 2012-08-07 더 스크립스 리서치 인스티튜트 진핵 유전자 코드의 확장
CA2527877A1 (en) 2003-06-18 2005-01-13 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
ES2301099T3 (es) * 2003-07-07 2008-06-16 The Scripps Research Institute Composiciones de parejas ortogonales lisil-arnt y aminoacil-arnt sintetasa y usos de las mismas.
MXPA06013586A (es) * 2004-05-25 2007-11-09 Scripss Res Inst Incorporacion especifica del sitio de aminoacidos no naturales que contienen atomos pesados en proteinas para la determinacion de la estructura cristalina.
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
WO2006036779A2 (en) * 2004-09-22 2006-04-06 The Scripps Research Institute Site-specific labeling of proteins for nmr studies
WO2006110182A2 (en) 2004-10-27 2006-10-19 The Scripps Research Institute Orthogonal translation components for the in vivo incorporation of unnatural amino acids
US8367588B2 (en) * 2005-10-12 2013-02-05 The Scripps Research Institute Selective posttranslational modification of phage-displayed polypeptides
US7776535B2 (en) 2006-02-06 2010-08-17 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
ES2432391T3 (es) * 2006-03-09 2013-12-03 The Scripps Research Institute Sistema para la expresión de componentes de traducción ortogonales en células huésped eubacterianas
BRPI0709603A2 (pt) 2006-03-16 2011-07-19 Scripps Research Inst expressão de proteìnas geneticamente programada contendo o aminoácido não natural fenilselenocisteìna
CA2652894A1 (en) * 2006-05-23 2007-12-06 The Scripps Research Institute Genetically encoded fluorescent coumarin amino acids
EP2052083B1 (en) 2006-09-21 2014-01-08 The Scripps Research Institute Genetically programmed expression of selectively sulfated proteins in eubacteria
EP2069481A4 (en) 2006-10-18 2010-01-06 Scripps Research Inst GENETIC ASSEMBLY OF UNNATURAL AMINO ACIDS IN PROTEINS IN MAMMALIAN CELLS
WO2008137452A1 (en) * 2007-05-04 2008-11-13 Kenergy Royalty Company, Llc Implantable high efficiency digital stimulation device
CA2703736A1 (en) 2007-10-25 2009-04-30 The Scripps Research Institute Genetic incorporation of 3-aminotyrosine into reductases
CA2704494A1 (en) * 2007-11-02 2009-05-14 The Scripps Research Institute Directed evolution using proteins comprising unnatural amino acids
US20090148887A1 (en) * 2007-11-02 2009-06-11 The Scripps Research Institute Genetically encoded boronate amino acid
EP2889370A1 (en) 2007-12-11 2015-07-01 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris
JP2011514322A (ja) * 2008-02-08 2011-05-06 ザ スクリプス リサーチ インスティチュート 遺伝的にコードされる非天然アミノ酸による免疫寛容解除
EP2373224A1 (en) * 2008-12-09 2011-10-12 Wilson-Cook Medical Inc. Apparatus and methods for controlled release of tacking devices
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
JP5959201B2 (ja) 2008-12-10 2016-08-02 ザ スクリプス リサーチ インスティテュート 化学的に反応性の非天然アミノ酸を使用するキャリア−ペプチド接合体の製造
WO2010089741A1 (en) * 2009-02-04 2010-08-12 Ben-Gurion University Of The Negev Research And Development Authority Systems and methods for bio-electricity production
EP2976362B1 (en) 2013-03-19 2019-10-23 Beijing Shenogen Pharma Group Ltd. Antibodies and methods for treating estrogen receptor-associated diseases
US20150331624A1 (en) * 2014-05-19 2015-11-19 Kabushiki Kaisha Toshiba Host-controlled flash translation layer snapshot
KR101956042B1 (ko) * 2017-07-13 2019-03-08 서강대학교산학협력단 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법
KR20220024586A (ko) 2019-06-17 2022-03-03 메르크 파텐트 게엠베하 액정-기반 광 밸브

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879905A (en) * 1996-08-29 1999-03-09 Massachusetts Institute Of Technology In vivo method of initiating protein synthesis with an amino acid other than methionine
DK2322631T3 (en) 2001-04-19 2015-01-12 Scripps Research Inst Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar
US7432092B2 (en) 2002-10-16 2008-10-07 The Scripps Research Institute Site specific incorporation of keto amino acids into proteins
CA2500653A1 (en) 2002-10-16 2004-04-29 The Scripps Research Institute Glycoprotein synthesis
EP1583816A4 (en) 2002-12-22 2007-06-13 Scripps Research Inst PROTEIN ARRAYS
KR101171397B1 (ko) 2003-04-17 2012-08-07 더 스크립스 리서치 인스티튜트 진핵 유전자 코드의 확장
CA2527877A1 (en) 2003-06-18 2005-01-13 The Scripps Research Institute Unnatural reactive amino acid genetic code additions
EP1658366A4 (en) 2003-07-07 2006-08-09 Scripps Research Inst COMPOSITIONS OF ORTHOGONAL GLUTAMYL-TRNA AND AMINOACYL-TRNA-SYNTHETASEPAARES AND THEIR USES
WO2005007870A2 (en) 2003-07-07 2005-01-27 The Scripps Research Institute COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF
ES2301099T3 (es) 2003-07-07 2008-06-16 The Scripps Research Institute Composiciones de parejas ortogonales lisil-arnt y aminoacil-arnt sintetasa y usos de las mismas.

Also Published As

Publication number Publication date
WO2005038002A2 (en) 2005-04-28
PT1687401E (pt) 2013-02-26
WO2005038002A3 (en) 2006-11-23
BRPI0415308A (pt) 2006-12-05
EP1687401B1 (en) 2012-11-21
CN101532046A (zh) 2009-09-16
AU2004282577B2 (en) 2009-10-29
ES2396712T3 (es) 2013-02-25
US9783798B2 (en) 2017-10-10
AU2004282577A1 (en) 2005-04-28
MXPA06004087A (es) 2006-06-27
EP1687401A2 (en) 2006-08-09
US7494796B2 (en) 2009-02-24
US8114654B2 (en) 2012-02-14
IL206889A0 (en) 2010-12-30
IL174947A (en) 2011-11-30
PL1687401T3 (pl) 2013-04-30
CN1942579A (zh) 2007-04-04
CA2541166A1 (en) 2005-04-28
IL201705A0 (en) 2011-08-01
JP5657850B2 (ja) 2015-01-21
IL174947A0 (en) 2006-08-20
US20050227318A1 (en) 2005-10-13
US7811801B2 (en) 2010-10-12
US20090298124A1 (en) 2009-12-03
US20070009990A1 (en) 2007-01-11
JP2007508034A (ja) 2007-04-05
US8008041B2 (en) 2011-08-30
EP1687401A4 (en) 2007-08-01
US20110008782A1 (en) 2011-01-13
US20120100570A1 (en) 2012-04-26
CN1942579B (zh) 2013-06-26

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