DK1687401T3 - Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener - Google Patents

Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener

Info

Publication number
DK1687401T3
DK1687401T3 DK04795276.7T DK04795276T DK1687401T3 DK 1687401 T3 DK1687401 T3 DK 1687401T3 DK 04795276 T DK04795276 T DK 04795276T DK 1687401 T3 DK1687401 T3 DK 1687401T3
Authority
DK
Denmark
Prior art keywords
protiens
redox
site
amino acids
active amino
Prior art date
Application number
DK04795276.7T
Other languages
Danish (da)
English (en)
Inventor
Lital Alfonta
Peter G Schultz
Zhiwen Zhang
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK1687401T3 publication Critical patent/DK1687401T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK04795276.7T 2003-10-14 2004-10-13 Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener DK1687401T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51153203P 2003-10-14 2003-10-14
PCT/US2004/034089 WO2005038002A2 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins

Publications (1)

Publication Number Publication Date
DK1687401T3 true DK1687401T3 (da) 2013-02-04

Family

ID=34465242

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04795276.7T DK1687401T3 (da) 2003-10-14 2004-10-13 Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener

Country Status (14)

Country Link
US (5) US8008041B2 (enExample)
EP (1) EP1687401B1 (enExample)
JP (1) JP5657850B2 (enExample)
CN (2) CN101532046A (enExample)
AU (1) AU2004282577B2 (enExample)
BR (1) BRPI0415308A (enExample)
CA (1) CA2541166A1 (enExample)
DK (1) DK1687401T3 (enExample)
ES (1) ES2396712T3 (enExample)
IL (3) IL174947A (enExample)
MX (1) MXPA06004087A (enExample)
PL (1) PL1687401T3 (enExample)
PT (1) PT1687401E (enExample)
WO (1) WO2005038002A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2322631T3 (en) * 2001-04-19 2015-01-12 Scripps Research Inst Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar
US6927042B2 (en) * 2002-10-16 2005-08-09 The Scripps Research Institute Glycoprotein synthesis
CN103215227B (zh) 2003-04-17 2015-09-16 斯克利普斯研究院 扩展真核生物遗传密码
CN102618605B (zh) 2003-06-18 2015-09-02 斯克利普斯研究院 非天然活性氨基酸遗传密码增加
CN101076598B (zh) 2003-07-07 2012-07-25 斯克利普斯研究院 正交赖氨酰-tRNA和氨酰-tRNA合成酶对的组合物及其应用
MXPA06013586A (es) * 2004-05-25 2007-11-09 Scripss Res Inst Incorporacion especifica del sitio de aminoacidos no naturales que contienen atomos pesados en proteinas para la determinacion de la estructura cristalina.
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
US20080171317A1 (en) * 2004-09-22 2008-07-17 The Scripps Research Institute Site-Specific Labeling of Proteins for Nmr Studies
JP5135504B2 (ja) 2004-10-27 2013-02-06 ザ スクリプス リサーチ インスティチュート 非天然アミノ酸のインビボ組込み用直交翻訳成分
KR20080069993A (ko) * 2005-10-12 2008-07-29 더 스크립스 리서치 인스티튜트 파지-디스플레이된 폴리펩티드의 선별적인 번역후 변형
WO2007092475A2 (en) * 2006-02-06 2007-08-16 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
BRPI0709935A2 (pt) * 2006-03-09 2011-08-02 Scripps Research Inst sistemas para a expressão de componentes ortogonais de tradução em células hospedeiras eubacterianas
MX2008011669A (es) * 2006-03-16 2008-09-22 Scripps Research Inst Expresion programada geneticamente de proteinas que contienen el aminoacido no natural fenilselenocisteina.
KR20090024706A (ko) * 2006-05-23 2009-03-09 더 스크립스 리서치 인스티튜트 유전자적으로 코딩된 형광 쿠마린 아미노산
EP2052083B1 (en) * 2006-09-21 2014-01-08 The Scripps Research Institute Genetically programmed expression of selectively sulfated proteins in eubacteria
KR20090094812A (ko) 2006-10-18 2009-09-08 더 스크립스 리서치 인스티튜트 포유동물 세포에서 비천연 아미노산의 단백질 내로의 유전적 도입
WO2008137452A1 (en) * 2007-05-04 2008-11-13 Kenergy Royalty Company, Llc Implantable high efficiency digital stimulation device
US8673591B2 (en) 2007-10-25 2014-03-18 The Scripps Research Institute Genetic incorporation of 3-aminotyrosine into reductases
AU2008325239A1 (en) 2007-11-02 2009-05-14 The Scripps Research Institute Directed evolution using proteins comprising unnatural amino acids
US20090148887A1 (en) * 2007-11-02 2009-06-11 The Scripps Research Institute Genetically encoded boronate amino acid
WO2009075847A2 (en) 2007-12-11 2009-06-18 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
KR20100125290A (ko) * 2008-02-08 2010-11-30 더 스크립스 리서치 인스티튜트 유전적으로 코딩된 비천연 아미노산에 의한 면역 내성의 파괴
AU2009333554A1 (en) * 2008-12-09 2011-06-30 Cook Medical Technologies Llc Apparatus and methods for controlled release of tacking devices
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
US8609383B2 (en) 2008-12-10 2013-12-17 The Scripps Research Institute Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
US9017978B2 (en) * 2009-02-04 2015-04-28 Bengurion University Of The Negev Research And Development Authority Systems and method for bio-electricity production
EP2976362B1 (en) 2013-03-19 2019-10-23 Beijing Shenogen Pharma Group Ltd. Antibodies and methods for treating estrogen receptor-associated diseases
US20150331624A1 (en) * 2014-05-19 2015-11-19 Kabushiki Kaisha Toshiba Host-controlled flash translation layer snapshot
KR101956042B1 (ko) * 2017-07-13 2019-03-08 서강대학교산학협력단 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법
KR20220024586A (ko) 2019-06-17 2022-03-03 메르크 파텐트 게엠베하 액정-기반 광 밸브

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879905A (en) * 1996-08-29 1999-03-09 Massachusetts Institute Of Technology In vivo method of initiating protein synthesis with an amino acid other than methionine
DK2322631T3 (en) 2001-04-19 2015-01-12 Scripps Research Inst Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar
US6927042B2 (en) 2002-10-16 2005-08-09 The Scripps Research Institute Glycoprotein synthesis
DK1578949T3 (da) 2002-10-16 2009-07-27 Scripps Research Inst Stedspecifik optagelse af keto-aminnosyrer hos proteiner
MXPA05006836A (es) 2002-12-22 2005-08-16 Scripps Research Inst Colecciones ordenadas de proteinas.
CN103215227B (zh) 2003-04-17 2015-09-16 斯克利普斯研究院 扩展真核生物遗传密码
CN102618605B (zh) 2003-06-18 2015-09-02 斯克利普斯研究院 非天然活性氨基酸遗传密码增加
EP1704242A4 (en) 2003-07-07 2008-06-18 Scripps Research Inst COMPOSITIONS WITH PAIRS OF ORTHOGONAL LEUCYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF
CN101076598B (zh) 2003-07-07 2012-07-25 斯克利普斯研究院 正交赖氨酰-tRNA和氨酰-tRNA合成酶对的组合物及其应用
US7527943B2 (en) 2003-07-07 2009-05-05 The Scripps Research Institute Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof

Also Published As

Publication number Publication date
WO2005038002A3 (en) 2006-11-23
CN101532046A (zh) 2009-09-16
MXPA06004087A (es) 2006-06-27
US9783798B2 (en) 2017-10-10
US7811801B2 (en) 2010-10-12
BRPI0415308A (pt) 2006-12-05
EP1687401A4 (en) 2007-08-01
PL1687401T3 (pl) 2013-04-30
PT1687401E (pt) 2013-02-26
US8114654B2 (en) 2012-02-14
US20050227318A1 (en) 2005-10-13
US20110008782A1 (en) 2011-01-13
IL206889A0 (en) 2010-12-30
CN1942579B (zh) 2013-06-26
IL174947A0 (en) 2006-08-20
US7494796B2 (en) 2009-02-24
EP1687401B1 (en) 2012-11-21
CN1942579A (zh) 2007-04-04
IL201705A0 (en) 2011-08-01
US8008041B2 (en) 2011-08-30
IL174947A (en) 2011-11-30
AU2004282577A1 (en) 2005-04-28
US20070009990A1 (en) 2007-01-11
EP1687401A2 (en) 2006-08-09
AU2004282577B2 (en) 2009-10-29
CA2541166A1 (en) 2005-04-28
US20090298124A1 (en) 2009-12-03
WO2005038002A2 (en) 2005-04-28
US20120100570A1 (en) 2012-04-26
ES2396712T3 (es) 2013-02-25
JP5657850B2 (ja) 2015-01-21
JP2007508034A (ja) 2007-04-05

Similar Documents

Publication Publication Date Title
DK1687401T3 (da) Sted-spicifik inkorporing af redoxaktive aminosyrer i protiener
ATE517887T1 (de) Neue 2-pyridincarbonsäureamidderivate
NO20054958D0 (no) Substitulerte aminokarboksylsyrer
DK1663936T3 (da) Biaryloxymethylaren-carboxylsyrer
DK1517915T3 (da) Promedikamenter af excitatoriske aminosyrer
DE60236949D1 (de) Pneumatisch angetriebener autoinjektor
ATE509913T1 (de) Heterozyklische diamide zur bekämpfung wirbelloser schädlinge
DK2035554T3 (da) Celle-fri syntese af proteiner indeholdende ikke-naturlige aminosyrer
IS3027B (is) Hraðuppleysandi samsetning af kalsíum viðtaka-virku efnasambandi
HUS1500024I1 (hu) GLP-1 analóg fúziós proteinek
DE602004008136D1 (de) Härtbare Zusammensetzung
PT2339014E (pt) Métodos e composições compreendendo aminoácidos não-naturais
FR2862654B1 (fr) Composition amylacee filmogene
NO20042172L (no) Insulinmolekyl med forlenget virkningstid
IS8450A (is) Amíðafleiður
NO20050132D0 (no) Vaksinesammensetning
NO20033078L (no) Hydrolysat av fiskeprotein
DE10393374D2 (de) Zusammensetzung
EP1559433A4 (en) STABILIZED COMPOSITION
ATE427953T1 (de) Fondaparinux- natrium zusammenstellung von hoher reinheit
DE60217089D1 (de) Lipidsenkende biphenylcarbonsäureamide
SE0500163L (sv) Sammansättning
FI20030466L (fi) Liimausainekoostumus
DK1654280T3 (da) Fremstilling af somatostatinpeptider
EP1561467A4 (en) COMPOSITION FOR RECOVERING DAMAGED SKIN