CY1109207T1 - Διαδικασια εχινοκανδινης - Google Patents

Διαδικασια εχινοκανδινης

Info

Publication number
CY1109207T1
CY1109207T1 CY20091100689T CY091100689T CY1109207T1 CY 1109207 T1 CY1109207 T1 CY 1109207T1 CY 20091100689 T CY20091100689 T CY 20091100689T CY 091100689 T CY091100689 T CY 091100689T CY 1109207 T1 CY1109207 T1 CY 1109207T1
Authority
CY
Cyprus
Prior art keywords
procedure
echinocandini
acid
echinocandins
minimizing
Prior art date
Application number
CY20091100689T
Other languages
English (en)
Inventor
Kevin M Belyk
William R Leonard Jr
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of CY1109207T1 publication Critical patent/CY1109207T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με βελτιωμένη διαδικασία για την ελαχιστοποίηση των καταλυόμενων από οξέα αντιδράσεων ορισμένων εχινοκανδινών του είδους που αποκλύπτονται στο Δίπλωμα Ευρεσιτεχνίας ΗΠΑ Αρ. 5,378,804. Η διαδικασία περιλαμβάνει τη χρήση βορονικού οξέος.
CY20091100689T 2001-04-12 2009-06-30 Διαδικασια εχινοκανδινης CY1109207T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28329701P 2001-04-12 2001-04-12
EP02725776A EP1392722B1 (en) 2001-04-12 2002-04-08 Echinocandin process

Publications (1)

Publication Number Publication Date
CY1109207T1 true CY1109207T1 (el) 2014-07-02

Family

ID=23085377

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100689T CY1109207T1 (el) 2001-04-12 2009-06-30 Διαδικασια εχινοκανδινης

Country Status (14)

Country Link
EP (1) EP1392722B1 (el)
JP (1) JP4272432B2 (el)
AR (1) AR035808A1 (el)
AT (1) ATE427957T1 (el)
AU (1) AU2002256323B2 (el)
CA (1) CA2443702C (el)
CY (1) CY1109207T1 (el)
DE (1) DE60231872D1 (el)
DK (1) DK1392722T3 (el)
ES (1) ES2322243T3 (el)
PT (1) PT1392722E (el)
SI (1) SI1392722T1 (el)
TW (1) TWI324610B (el)
WO (1) WO2002083713A2 (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1785432A1 (en) 2005-11-15 2007-05-16 Sandoz AG Process and intermediates for the synthesis of caspofungin.
EP2463293A4 (en) * 2009-08-06 2013-06-05 Shanghai Techwell Biopharm Co AZACYCLOHEXAPEPTIDE BZW. ITS PHARMACEUTICAL ACCEPTABLE SALT, MANUFACTURING PROCESS AND USE
CN102947327B (zh) 2010-03-29 2017-06-13 中化帝斯曼制药有限公司荷兰公司 卡泊芬净中间体的纯化
CN101792486A (zh) * 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
CN102367267B (zh) 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
WO2012093293A1 (en) * 2011-01-03 2012-07-12 Biocon Limited Process for preparation of caspofungin acetate and intermediates
CN102746384B (zh) 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
MX2013012161A (es) 2011-04-28 2014-07-30 Unitris Biopharma Co Ltd Compuesto intermedio de la sintesis de caspofungina y metodo de preparacion de la misma.
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939384A (en) * 1991-10-01 1999-08-17 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
US5936062A (en) * 1997-06-12 1999-08-10 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
WO2000012540A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Reversible boronate complexes of 1,2-cis-diol cyclic-peptides

Also Published As

Publication number Publication date
PT1392722E (pt) 2009-05-25
JP4272432B2 (ja) 2009-06-03
TWI324610B (en) 2010-05-11
DE60231872D1 (en) 2009-05-20
CA2443702C (en) 2012-09-18
WO2002083713A2 (en) 2002-10-24
EP1392722B1 (en) 2009-04-08
JP2004529146A (ja) 2004-09-24
CA2443702A1 (en) 2002-10-24
SI1392722T1 (sl) 2009-10-31
AR035808A1 (es) 2004-07-14
EP1392722A4 (en) 2007-04-18
WO2002083713A3 (en) 2003-02-27
DK1392722T3 (da) 2009-08-10
EP1392722A2 (en) 2004-03-03
AU2002256323B2 (en) 2007-05-24
ATE427957T1 (de) 2009-04-15
ES2322243T3 (es) 2009-06-18

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