BRPI0200320B1 - bactéria corineforme transgênica, e, método para produzir l-glutamina - Google Patents
bactéria corineforme transgênica, e, método para produzir l-glutamina Download PDFInfo
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- BRPI0200320B1 BRPI0200320B1 BRPI0200320A BR0200320A BRPI0200320B1 BR PI0200320 B1 BRPI0200320 B1 BR PI0200320B1 BR PI0200320 A BRPI0200320 A BR PI0200320A BR 0200320 A BR0200320 A BR 0200320A BR PI0200320 B1 BRPI0200320 B1 BR PI0200320B1
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- Prior art keywords
- glutamine
- gene
- activity
- dna
- strain
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
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- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001028163 | 2001-02-05 | ||
| JP2001162806A JP4560998B2 (ja) | 2001-02-05 | 2001-05-30 | 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌 |
Publications (2)
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| BR0200320A BR0200320A (pt) | 2002-10-29 |
| BRPI0200320B1 true BRPI0200320B1 (pt) | 2016-07-26 |
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| BRPI0200320A BRPI0200320B1 (pt) | 2001-02-05 | 2002-02-04 | bactéria corineforme transgênica, e, método para produzir l-glutamina |
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|---|---|
| US (2) | US7262035B2 (enExample) |
| EP (2) | EP1229121B1 (enExample) |
| JP (1) | JP4560998B2 (enExample) |
| CN (1) | CN100457894C (enExample) |
| BR (1) | BRPI0200320B1 (enExample) |
| DE (1) | DE60208450T2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU756507B2 (en) * | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるｌ−グルタミン酸の製造法 |
| JP4560998B2 (ja) * | 2001-02-05 | 2010-10-13 | 味の素株式会社 | 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌 |
| JP4599726B2 (ja) | 2001-02-20 | 2010-12-15 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| DE60335774D1 (de) * | 2002-11-26 | 2011-03-03 | Ajinomoto Kk | Methode für die Produktion von L-Glutamin und L-Glutamin-produzierendes Bakterium |
| JP2004187684A (ja) * | 2002-11-26 | 2004-07-08 | Ajinomoto Co Inc | Ｌ−グルタミンの製造法及びｌ−グルタミン生産菌 |
| JP4576850B2 (ja) * | 2003-03-03 | 2010-11-10 | 味の素株式会社 | 発酵法によるｌ−アルギニン又はｌ−リジンの製造法 |
| US20050014236A1 (en) * | 2003-03-03 | 2005-01-20 | Yumi Matsuzaki | Method for producing L-arginine or L-lysine by fermentation |
| JP5325372B2 (ja) * | 2003-05-07 | 2013-10-23 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| DE10344739A1 (de) * | 2003-09-26 | 2005-04-14 | Degussa Ag | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| DE602005019063D1 (de) | 2004-06-25 | 2010-03-11 | Kyowa Hakko Bio Co Ltd | Verfahren zur herstellung von substanzen |
| WO2007074857A1 (ja) | 2005-12-27 | 2007-07-05 | Kyowa Hakko Kogyo Co., Ltd. | Ｌ－グルタミンの製造法 |
| EP2612915B1 (en) | 2006-09-01 | 2015-04-08 | Kyowa Hakko Bio Co., Ltd. | Method for production of L-Glutamine |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | Ｌ−アミノ酸または核酸の製造方法 |
| JP2010130899A (ja) * | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| JP2011512144A (ja) * | 2008-02-21 | 2011-04-21 | ビーエーエスエフ ソシエタス・ヨーロピア | γ−アミノ酪酸の生産方法 |
| RU2418064C2 (ru) * | 2009-01-23 | 2011-05-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ СЕМЕЙСТВА ГЛУТАМАТА ИЛИ L-ВАЛИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia |
| RU2420586C2 (ru) * | 2009-01-23 | 2011-06-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Способ получения l-аминокислоты семейства глутамата с использованием бактерии, принадлежащей к роду escherichia |
| JP2012223091A (ja) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| WO2011083859A1 (ja) | 2010-01-08 | 2011-07-14 | 協和発酵バイオ株式会社 | Ｌ－グルタミンまたはｌ－グルタミン酸の製造法 |
| US8859241B2 (en) | 2010-01-08 | 2014-10-14 | Kyowa Hakko Bio Co., Ltd. | Process for production of L-amino acid |
| RU2496867C2 (ru) * | 2011-04-25 | 2013-10-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии |
| US9822387B2 (en) | 2011-07-29 | 2017-11-21 | Mitsui Chemicals, Inc. | Microorganism having carbon dioxide fixation pathway introduced thereinto |
| PE20141569A1 (es) | 2011-11-11 | 2014-11-08 | Ajinomoto Kk | Metodo para producir una sustancia diana mediante fermentacion |
| US9828618B2 (en) | 2013-01-24 | 2017-11-28 | Mitsui Chemicals, Inc. | Microorganism having carbon dioxide fixation cycle introduced thereinto |
| KR101773755B1 (ko) | 2013-05-13 | 2017-09-01 | 아지노모토 가부시키가이샤 | Ｌ-아미노산의 제조법 |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
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| EP3061828B1 (en) | 2013-10-23 | 2024-08-28 | Ajinomoto Co., Inc. | Method for producing target substance |
| CN103695491B (zh) * | 2013-12-24 | 2016-08-24 | 山东民强生物科技股份有限公司 | L-谷氨酰胺的精制方法 |
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| EP3861109A1 (en) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
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| EP4239070A4 (en) | 2020-10-28 | 2025-09-10 | Ajinomoto Kk | PROCESS FOR THE PRODUCTION OF L-AMINO ACID |
| EP4230743A4 (en) | 2020-11-20 | 2024-04-17 | CJ Cheiljedang Corporation | MICROORGANISM WITH IMPROVED L-GLUTAMINE PRODUCTION CAPABILITY AND L-GLUTAMINE PRODUCTION PROCESS THEREFOR |
| CN112646766B (zh) * | 2020-12-30 | 2023-08-18 | 内蒙古伊品生物科技有限公司 | 一种改造基因bbd29_04920的产l-谷氨酸的重组菌株及其构建方法与应用 |
| CN113817627B (zh) * | 2021-07-15 | 2023-04-28 | 大连医诺生物股份有限公司 | 一种嗜乙酰乙酸棒杆菌及以氨态氮浓度控制进行谷氨酰胺发酵的方法 |
| CN113684165B (zh) * | 2021-08-12 | 2023-07-25 | 江南大学 | 一种重组谷氨酸棒杆菌及其在生产l-谷氨酰胺中的应用 |
| US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
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| JPS5317675B2 (enExample) * | 1972-12-16 | 1978-06-09 | ||
| US3888039A (en) * | 1974-01-11 | 1975-06-10 | Quaker Oats Co | Foldable toy building |
| GB9111872D0 (en) | 1991-06-03 | 1991-07-24 | Shell Int Research | Polymer process |
| FR2736066B1 (fr) * | 1995-06-30 | 1998-11-20 | Ajinomoto Kk | Procede d'amplification d'un gene par transposon artificiel, bacterie coryneforme obtenue par ce procede et procede de production d'un acide amine a l'aide de cette bacterie |
| AU756507B2 (en) * | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| PE20001128A1 (es) * | 1998-10-19 | 2000-11-14 | Ajinomoto Kk | Bacteria productora del acido l-glutamico y procedimiento para obtener el acido l-glutamico |
| CN1067434C (zh) * | 1998-12-28 | 2001-06-20 | 山东大学 | 一种谷氨酰胺发酵生产工艺 |
| MXPA01013123A (es) * | 1999-06-25 | 2002-06-21 | Basf Ag | Genes de corynebacterium glutamicum que codifican proteinas de via metabolica. |
| JP4427878B2 (ja) * | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるｌ−グルタミン酸の製造法 |
| JP4304837B2 (ja) * | 2000-07-05 | 2009-07-29 | 味の素株式会社 | Ｌ−グルタミン酸生産菌及びｌ−グルタミン酸の製造法 |
| JP4560998B2 (ja) * | 2001-02-05 | 2010-10-13 | 味の素株式会社 | 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌 |
| JP2002238592A (ja) * | 2001-02-20 | 2002-08-27 | Ajinomoto Co Inc | Ｌ−グルタミン酸の製造法 |
| RU2230114C2 (ru) * | 2001-11-30 | 2004-06-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Мутантная глутаминсинтетаза, фрагмент днк, штамм escherichia coli - продуцент l-глутамина и способ получения l-аминокислот |
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- 2002-02-05 US US10/062,458 patent/US7262035B2/en not_active Expired - Lifetime
- 2002-02-05 CN CNB021205817A patent/CN100457894C/zh not_active Expired - Lifetime
- 2002-02-05 DE DE60208450T patent/DE60208450T2/de not_active Expired - Lifetime
- 2002-02-05 EP EP04000167A patent/EP1424398A3/en not_active Withdrawn
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- 2006-12-27 US US11/616,463 patent/US20070092953A1/en not_active Abandoned
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| US20070092953A1 (en) | 2007-04-26 |
| CN100457894C (zh) | 2009-02-04 |
| DE60208450D1 (de) | 2006-03-30 |
| BR0200320A (pt) | 2002-10-29 |
| EP1424398A2 (en) | 2004-06-02 |
| CN1384190A (zh) | 2002-12-11 |
| DE60208450T2 (de) | 2006-08-24 |
| US20030003550A1 (en) | 2003-01-02 |
| JP4560998B2 (ja) | 2010-10-13 |
| EP1229121B1 (en) | 2006-01-04 |
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| EP1229121A3 (en) | 2003-03-12 |
| JP2002300887A (ja) | 2002-10-15 |
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