BR9809916A - Processo de precipitação melhorada de ácido 7-aminocefalosporânico (7-aca) - Google Patents

Processo de precipitação melhorada de ácido 7-aminocefalosporânico (7-aca)

Info

Publication number
BR9809916A
BR9809916A BR9809916-7A BR9809916A BR9809916A BR 9809916 A BR9809916 A BR 9809916A BR 9809916 A BR9809916 A BR 9809916A BR 9809916 A BR9809916 A BR 9809916A
Authority
BR
Brazil
Prior art keywords
aca
aminocephalosporanic acid
precipitation process
improved precipitation
esters
Prior art date
Application number
BR9809916-7A
Other languages
English (en)
Inventor
Petr Nadenik
Helmut Wagner
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT95197A external-priority patent/AT404833B/de
Priority claimed from AT111297A external-priority patent/AT404834B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of BR9809916A publication Critical patent/BR9809916A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
  • Phenolic Resins Or Amino Resins (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO DE PRECIPITAçãO MELHORADA DE áCIDO 7-AMINOCEFALOSPORâNICO (7-ACA)"<D>. Um processo de isolamento de ácido 7-aminocefalosporânico (7-ACA) de um meio alcalino, neutro ou ligeiramente ácido, na presença de um aditivo, por exemplo selecionado do grupo que compreende ésteres orgânicos de ácidos carboxílicos, glicóis poliméricos, poliacrílicos, aminas e poliaminas, resinas melamina-formaldeído ou aminoácidos e ésteres dos mesmos, para obter aglomerados e/ou rosetas de 7-ACA.
BR9809916-7A 1997-06-04 1998-06-02 Processo de precipitação melhorada de ácido 7-aminocefalosporânico (7-aca) BR9809916A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT95197A AT404833B (de) 1997-06-04 1997-06-04 Verfahren zur isolierung der 7-aminocephalosporansäure (7-aca)
AT111297A AT404834B (de) 1997-06-30 1997-06-30 Verfahren zur isolierung der 7-aminocephalosporansäure (7-aca)
PCT/EP1998/003278 WO1998055484A1 (en) 1997-06-04 1998-06-02 Improved precipitation process of 7-aminocephalosporanic acid (7-aca)

Publications (1)

Publication Number Publication Date
BR9809916A true BR9809916A (pt) 2000-10-03

Family

ID=25594420

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809916-7A BR9809916A (pt) 1997-06-04 1998-06-02 Processo de precipitação melhorada de ácido 7-aminocefalosporânico (7-aca)

Country Status (15)

Country Link
EP (1) EP0986565B1 (pt)
JP (1) JP3658000B2 (pt)
KR (1) KR100748387B1 (pt)
CN (1) CN1158289C (pt)
AR (1) AR012903A1 (pt)
AT (1) ATE420884T1 (pt)
AU (1) AU735188B2 (pt)
BR (1) BR9809916A (pt)
CA (1) CA2292618C (pt)
DE (1) DE69840475D1 (pt)
DK (1) DK0986565T3 (pt)
ES (1) ES2320940T3 (pt)
SI (1) SI0986565T1 (pt)
SK (1) SK165399A3 (pt)
WO (1) WO1998055484A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100509737B1 (ko) * 2001-10-06 2005-08-23 종근당바이오 주식회사 7-아미노세팔로스포란산의 결정화 방법
CN102321099A (zh) * 2011-08-15 2012-01-18 华北制药河北华民药业有限责任公司 一种头孢烷酸的结晶方法
CN104402905B (zh) * 2014-10-30 2017-02-01 华北制药河北华民药业有限责任公司 从7‑氨基头孢烷酸母液中回收7‑氨基头孢烷酸的方法
CN104557976A (zh) * 2014-12-31 2015-04-29 西安蓝晓科技新材料股份有限公司 一种7-aca结晶母液回收的工艺
CN106117245B (zh) * 2016-06-16 2019-01-22 天俱时工程科技集团有限公司 一种从7-aca结晶母液中直接回收7-aca的方法
CN109553628B (zh) * 2017-09-25 2021-03-09 联邦制药(内蒙古)有限公司 一种消除7-aca成品泡沫的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1104938A (en) * 1964-05-28 1968-03-06 Glaxo Lab Ltd Improvements in or relating to 7-aminocephalosporanic acid
GB1277228A (en) * 1968-10-07 1972-06-07 Lilly Co Eli An improved process for the production of 7-aminocephalosporanic acid
US3507862A (en) * 1968-12-26 1970-04-21 Lilly Co Eli Cleavage of cephalosporin c
ES414153A1 (es) * 1972-05-01 1976-06-01 Lilly Co Eli Un procedimiento de escision del grupo 7-carboxamido de unacefalosporina.
DE2222094A1 (de) * 1972-05-05 1973-11-15 Hoechst Ag Verfahren zur herstellung von aminoazetidinonen
BE824028A (fr) * 1974-01-23 1975-06-30 Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre
AT367060B (de) * 1979-01-25 1982-05-25 Biochemie Gmbh Verfahren zur herstellung neuer cephalosporinderivate
GB9322826D0 (en) * 1992-11-25 1993-12-22 Zeneca Ltd Compound
WO1994012504A1 (en) * 1992-12-02 1994-06-09 Fujisawa Pharmaceutical Co., Ltd. Method of purifying 7-aminocephalosporanic acid

Also Published As

Publication number Publication date
CA2292618C (en) 2007-07-31
EP0986565A1 (en) 2000-03-22
AU8212098A (en) 1998-12-21
WO1998055484A1 (en) 1998-12-10
SI0986565T1 (sl) 2009-06-30
AR012903A1 (es) 2000-11-22
CN1158289C (zh) 2004-07-21
CN1259133A (zh) 2000-07-05
DE69840475D1 (de) 2009-03-05
SK165399A3 (en) 2000-05-16
DK0986565T3 (da) 2009-04-20
JP3658000B2 (ja) 2005-06-08
ES2320940T3 (es) 2009-05-29
AU735188B2 (en) 2001-07-05
JP2001507717A (ja) 2001-06-12
KR100748387B1 (ko) 2007-08-10
EP0986565B1 (en) 2009-01-14
ATE420884T1 (de) 2009-01-15
CA2292618A1 (en) 1998-12-10
KR20010029543A (ko) 2001-04-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A,8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.