AT367060B - Verfahren zur herstellung neuer cephalosporinderivate - Google Patents
Verfahren zur herstellung neuer cephalosporinderivateInfo
- Publication number
- AT367060B AT367060B AT0053179A AT53179A AT367060B AT 367060 B AT367060 B AT 367060B AT 0053179 A AT0053179 A AT 0053179A AT 53179 A AT53179 A AT 53179A AT 367060 B AT367060 B AT 367060B
- Authority
- AT
- Austria
- Prior art keywords
- producing new
- cephalosporine derivatives
- new cephalosporine
- derivatives
- producing
- Prior art date
Links
- HOKIDJSKDBPKTQ-UHFFFAOYSA-N 3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 HOKIDJSKDBPKTQ-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (29)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0053179A AT367060B (de) | 1979-01-25 | 1979-01-25 | Verfahren zur herstellung neuer cephalosporinderivate |
| AT430680A AT375081B (de) | 1979-01-25 | 1979-01-25 | Verfahren zur herstellung von 7-aminocephalosporansaeure und ihren estern |
| CH31580A CH644865A5 (de) | 1979-01-25 | 1980-01-15 | Cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung als zwischenprodukte. |
| FI800132A FI73439C (fi) | 1979-01-25 | 1980-01-16 | Som mellanprodukter anvaendbara kefalosporinderivat och deras framstaellning. |
| DK019780A DK160050C (da) | 1979-01-25 | 1980-01-16 | Cephalosporinderivater, fremgangsmaade til fremstilling deraf samt deres anvendelse som mellemprodukter til fremstilling af 7-amino-cephalosporansyre |
| SE8000366A SE451136B (sv) | 1979-01-25 | 1980-01-16 | Nya cefalosporinderivat samt dess anvendning som mellanprodukt for framstellning av 7-amino-cefalosporinsyra |
| NL8000337A NL8000337A (nl) | 1979-01-25 | 1980-01-18 | Cefalosporinederivaten en werkwijzen voor het bereiden en toepassen van deze derivaten. |
| IT47648/80A IT1127336B (it) | 1979-01-25 | 1980-01-18 | Derivati della cefalosporina loro preparazione e loro impiego |
| AU54780/80A AU536763B2 (en) | 1979-01-25 | 1980-01-21 | Cephalosporin derivatives |
| GB8002089A GB2040942B (en) | 1979-01-25 | 1980-01-22 | Derivatives of cephalosporin c |
| US06/114,154 US4267321A (en) | 1979-01-25 | 1980-01-22 | Cephalosporin derivatives |
| IL59202A IL59202A (en) | 1979-01-25 | 1980-01-23 | Vinyl derivatives of cephalosporin c,their production and their use |
| CA000344273A CA1147723A (en) | 1979-01-25 | 1980-01-23 | Cephalosporin derivatives, their production and use |
| NZ192689A NZ192689A (en) | 1979-01-25 | 1980-01-23 | Cephalosporin derivatives |
| PT70720A PT70720A (en) | 1979-01-25 | 1980-01-23 | Process for the production of new cephalosporin derivatives having pharmacological properties |
| ES487955A ES8102138A1 (es) | 1979-01-25 | 1980-01-23 | Procedimiento para preparar nuevos derivados de cefalosporina |
| BE0/199082A BE881309A (fr) | 1979-01-25 | 1980-01-23 | Nouveaux derives de la cephalosporine,leur preparation et leur utilisation |
| YU175/80A YU42496B (en) | 1979-01-25 | 1980-01-23 | Process for preparing new cephalosporin derivatives |
| IE131/80A IE49368B1 (en) | 1979-01-25 | 1980-01-23 | Cephalosporin derivatives |
| JP770280A JPS55100392A (en) | 1979-01-25 | 1980-01-24 | Novel cephalosporin derivative* its manufacture and use |
| PH23548A PH23413A (en) | 1979-01-25 | 1980-01-24 | Cephalosporin derivatives |
| FR8001619A FR2447381A1 (fr) | 1979-01-25 | 1980-01-25 | Nouveaux derives de la cephalosporine, leur preparation et leur utilisation |
| ZA00800449A ZA80449B (en) | 1979-01-25 | 1980-01-25 | Cephalosporin derivatives |
| DE19803002659 DE3002659A1 (de) | 1979-01-25 | 1980-01-25 | Neue organische verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| ES494480A ES494480A0 (es) | 1979-01-25 | 1980-08-25 | Procedimiento para preparar nuevos derivados de cefalospori-na |
| ES494479A ES494479A0 (es) | 1979-01-25 | 1980-08-25 | Procedimiento para preparar derivados del acido 7-amino-ce- falosporanico |
| US06/220,830 US4322526A (en) | 1979-01-25 | 1980-12-29 | Process for producing 7-aminocephalosporanic acid |
| PH31637A PH24354A (en) | 1979-01-25 | 1984-12-17 | Cephalosporin derivatives |
| JP1085622A JPH02167289A (ja) | 1979-01-25 | 1989-04-04 | 新規セフアロスポリン誘導体の製法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0053179A AT367060B (de) | 1979-01-25 | 1979-01-25 | Verfahren zur herstellung neuer cephalosporinderivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA53179A ATA53179A (de) | 1981-10-15 |
| AT367060B true AT367060B (de) | 1982-05-25 |
Family
ID=3493085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0053179A AT367060B (de) | 1979-01-25 | 1979-01-25 | Verfahren zur herstellung neuer cephalosporinderivate |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US4267321A (de) |
| JP (2) | JPS55100392A (de) |
| AT (1) | AT367060B (de) |
| AU (1) | AU536763B2 (de) |
| BE (1) | BE881309A (de) |
| CA (1) | CA1147723A (de) |
| CH (1) | CH644865A5 (de) |
| DE (1) | DE3002659A1 (de) |
| DK (1) | DK160050C (de) |
| ES (3) | ES8102138A1 (de) |
| FI (1) | FI73439C (de) |
| FR (1) | FR2447381A1 (de) |
| GB (1) | GB2040942B (de) |
| IE (1) | IE49368B1 (de) |
| IL (1) | IL59202A (de) |
| IT (1) | IT1127336B (de) |
| NL (1) | NL8000337A (de) |
| NZ (1) | NZ192689A (de) |
| PH (2) | PH23413A (de) |
| PT (1) | PT70720A (de) |
| SE (1) | SE451136B (de) |
| YU (1) | YU42496B (de) |
| ZA (1) | ZA80449B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA815295B (en) * | 1980-08-01 | 1983-03-30 | Biochemie Gmbh | New cephalosporin derivatives,their production and their use |
| EP0045717B1 (de) * | 1980-08-01 | 1985-09-25 | BIOCHEMIE Gesellschaft m.b.H. | Cephalosporinderivate, ihre Herstellung und Anwendung |
| AT378774B (de) * | 1982-08-06 | 1985-09-25 | Biochemie Gmbh | Verfahren zur deacylierung von penicillinen und cephalosporinen |
| US5512454A (en) * | 1994-02-03 | 1996-04-30 | Bristol-Myers Squibb Company | Enzymatic acylation of 3-hydroxymethyl cephalosporins |
| KR100748387B1 (ko) * | 1997-06-04 | 2007-08-10 | 산도즈 게엠베하 | 7-아미노세팔로스포란산(7-ａｃａ)의 개선된 침전 방법 |
| US6518420B2 (en) | 1997-06-04 | 2003-02-11 | Biochemie Gesellschaft M.B.H. | Precipitation process of 7-aminocephalosporanic acid (7-ACA) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3227709A (en) * | 1961-11-28 | 1966-01-04 | Merck & Co Inc | Derivatives of cephalosporin c and process |
| US3234222A (en) * | 1962-02-16 | 1966-02-08 | Ciba Geigy Corp | Preparation of 7-acylaminocephalosporanic acids |
| US3234223A (en) * | 1962-02-16 | 1966-02-08 | Ciba Geigy Corp | Preparation of 7-amino-cephalosporanic acid and derivatives |
| NL6905073A (de) * | 1968-04-05 | 1969-10-07 | Glaxo Lab Ltd | |
| US3641018A (en) * | 1969-06-26 | 1972-02-08 | Lilly Co Eli | Process for preparing 7-amino cephalosporanic acid |
| GB1327270A (en) * | 1970-10-26 | 1973-08-22 | Osaka Univeristy President Of | Acylation of 6-aminopenicillanic acid and 7-aminocephalospor anic acids |
| SU603343A3 (ru) * | 1972-11-13 | 1978-04-15 | Эли Лилли Энд Компани (Фирма) | Способ очистки цефалоспорина с |
| US3880846A (en) * | 1972-12-19 | 1975-04-29 | Squibb & Sons Inc | Vinylaminoacetyl cephalosporins |
| US3931361A (en) * | 1974-12-23 | 1976-01-06 | Stauffer Chemical Company | Color improvement of phosphate esters |
-
1979
- 1979-01-25 AT AT0053179A patent/AT367060B/de not_active IP Right Cessation
-
1980
- 1980-01-15 CH CH31580A patent/CH644865A5/de not_active IP Right Cessation
- 1980-01-16 SE SE8000366A patent/SE451136B/sv not_active IP Right Cessation
- 1980-01-16 DK DK019780A patent/DK160050C/da not_active IP Right Cessation
- 1980-01-16 FI FI800132A patent/FI73439C/fi not_active IP Right Cessation
- 1980-01-18 NL NL8000337A patent/NL8000337A/nl not_active Application Discontinuation
- 1980-01-18 IT IT47648/80A patent/IT1127336B/it active
- 1980-01-21 AU AU54780/80A patent/AU536763B2/en not_active Ceased
- 1980-01-22 US US06/114,154 patent/US4267321A/en not_active Expired - Lifetime
- 1980-01-22 GB GB8002089A patent/GB2040942B/en not_active Expired
- 1980-01-23 IE IE131/80A patent/IE49368B1/en unknown
- 1980-01-23 ES ES487955A patent/ES8102138A1/es not_active Expired
- 1980-01-23 IL IL59202A patent/IL59202A/xx unknown
- 1980-01-23 CA CA000344273A patent/CA1147723A/en not_active Expired
- 1980-01-23 YU YU175/80A patent/YU42496B/xx unknown
- 1980-01-23 NZ NZ192689A patent/NZ192689A/xx unknown
- 1980-01-23 PT PT70720A patent/PT70720A/pt unknown
- 1980-01-23 BE BE0/199082A patent/BE881309A/fr not_active IP Right Cessation
- 1980-01-24 JP JP770280A patent/JPS55100392A/ja active Granted
- 1980-01-24 PH PH23548A patent/PH23413A/en unknown
- 1980-01-25 ZA ZA00800449A patent/ZA80449B/xx unknown
- 1980-01-25 FR FR8001619A patent/FR2447381A1/fr active Granted
- 1980-01-25 DE DE19803002659 patent/DE3002659A1/de not_active Withdrawn
- 1980-08-25 ES ES494479A patent/ES494479A0/es active Granted
- 1980-08-25 ES ES494480A patent/ES494480A0/es active Granted
- 1980-12-29 US US06/220,830 patent/US4322526A/en not_active Expired - Fee Related
-
1984
- 1984-12-17 PH PH31637A patent/PH24354A/en unknown
-
1989
- 1989-04-04 JP JP1085622A patent/JPH02167289A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
| ELJ | Ceased due to non-payment of the annual fee |