JPS55100392A - Novel cephalosporin derivative* its manufacture and use - Google Patents

Novel cephalosporin derivative* its manufacture and use

Info

Publication number
JPS55100392A
JPS55100392A JP770280A JP770280A JPS55100392A JP S55100392 A JPS55100392 A JP S55100392A JP 770280 A JP770280 A JP 770280A JP 770280 A JP770280 A JP 770280A JP S55100392 A JPS55100392 A JP S55100392A
Authority
JP
Japan
Prior art keywords
manufacture
cephalosporin derivative
novel cephalosporin
novel
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP770280A
Other languages
English (en)
Other versions
JPH0212953B2 (ja
Inventor
Atsushiyaa Gerudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of JPS55100392A publication Critical patent/JPS55100392A/ja
Publication of JPH0212953B2 publication Critical patent/JPH0212953B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP770280A 1979-01-25 1980-01-24 Novel cephalosporin derivative* its manufacture and use Granted JPS55100392A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0053179A AT367060B (de) 1979-01-25 1979-01-25 Verfahren zur herstellung neuer cephalosporinderivate

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1085622A Division JPH02167289A (ja) 1979-01-25 1989-04-04 新規セフアロスポリン誘導体の製法

Publications (2)

Publication Number Publication Date
JPS55100392A true JPS55100392A (en) 1980-07-31
JPH0212953B2 JPH0212953B2 (ja) 1990-03-30

Family

ID=3493085

Family Applications (2)

Application Number Title Priority Date Filing Date
JP770280A Granted JPS55100392A (en) 1979-01-25 1980-01-24 Novel cephalosporin derivative* its manufacture and use
JP1085622A Granted JPH02167289A (ja) 1979-01-25 1989-04-04 新規セフアロスポリン誘導体の製法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1085622A Granted JPH02167289A (ja) 1979-01-25 1989-04-04 新規セフアロスポリン誘導体の製法

Country Status (23)

Country Link
US (2) US4267321A (ja)
JP (2) JPS55100392A (ja)
AT (1) AT367060B (ja)
AU (1) AU536763B2 (ja)
BE (1) BE881309A (ja)
CA (1) CA1147723A (ja)
CH (1) CH644865A5 (ja)
DE (1) DE3002659A1 (ja)
DK (1) DK160050C (ja)
ES (3) ES487955A0 (ja)
FI (1) FI73439C (ja)
FR (1) FR2447381A1 (ja)
GB (1) GB2040942B (ja)
IE (1) IE49368B1 (ja)
IL (1) IL59202A (ja)
IT (1) IT1127336B (ja)
NL (1) NL8000337A (ja)
NZ (1) NZ192689A (ja)
PH (2) PH23413A (ja)
PT (1) PT70720A (ja)
SE (1) SE451136B (ja)
YU (1) YU42496B (ja)
ZA (1) ZA80449B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5758691A (en) * 1980-08-01 1982-04-08 Biochemie Gmbh Cephalosporin derivative, manufacture and use
JPH02160791A (ja) * 1980-08-01 1990-06-20 Biochem Gmbh セファロスポリン誘導体の製造法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT378774B (de) * 1982-08-06 1985-09-25 Biochemie Gmbh Verfahren zur deacylierung von penicillinen und cephalosporinen
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins
US6518420B2 (en) 1997-06-04 2003-02-11 Biochemie Gesellschaft M.B.H. Precipitation process of 7-aminocephalosporanic acid (7-ACA)
AR012903A1 (es) * 1997-06-04 2000-11-22 Biochemie Gmbh Procedimiento para la aislacion de acido 7-aminocefalosporanico (7-aca)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3227709A (en) * 1961-11-28 1966-01-04 Merck & Co Inc Derivatives of cephalosporin c and process
US3234223A (en) * 1962-02-16 1966-02-08 Ciba Geigy Corp Preparation of 7-amino-cephalosporanic acid and derivatives
US3234222A (en) * 1962-02-16 1966-02-08 Ciba Geigy Corp Preparation of 7-acylaminocephalosporanic acids
NL6905073A (ja) * 1968-04-05 1969-10-07 Glaxo Lab Ltd
US3641018A (en) * 1969-06-26 1972-02-08 Lilly Co Eli Process for preparing 7-amino cephalosporanic acid
GB1327270A (en) * 1970-10-26 1973-08-22 Osaka Univeristy President Of Acylation of 6-aminopenicillanic acid and 7-aminocephalospor anic acids
SU603343A3 (ru) * 1972-11-13 1978-04-15 Эли Лилли Энд Компани (Фирма) Способ очистки цефалоспорина с
US3880846A (en) * 1972-12-19 1975-04-29 Squibb & Sons Inc Vinylaminoacetyl cephalosporins
US3931361A (en) * 1974-12-23 1976-01-06 Stauffer Chemical Company Color improvement of phosphate esters

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5758691A (en) * 1980-08-01 1982-04-08 Biochemie Gmbh Cephalosporin derivative, manufacture and use
JPH02160791A (ja) * 1980-08-01 1990-06-20 Biochem Gmbh セファロスポリン誘導体の製造法

Also Published As

Publication number Publication date
IE800131L (en) 1980-07-25
GB2040942A (en) 1980-09-03
FI800132A (fi) 1980-07-26
ES8102138A1 (es) 1980-12-16
DK160050B (da) 1991-01-21
SE8000366L (sv) 1980-07-26
DE3002659A1 (de) 1980-07-31
FI73439B (fi) 1987-06-30
JPH0251915B2 (ja) 1990-11-08
ZA80449B (en) 1981-09-30
IT8047648A0 (it) 1980-01-18
ES494479A0 (es) 1981-08-16
YU17580A (en) 1983-06-30
FI73439C (fi) 1987-10-09
CH644865A5 (de) 1984-08-31
ES8106534A1 (es) 1981-08-16
IE49368B1 (en) 1985-09-18
CA1147723A (en) 1983-06-07
PH23413A (en) 1989-08-07
NZ192689A (en) 1982-09-14
AU536763B2 (en) 1984-05-24
YU42496B (en) 1988-10-31
IL59202A0 (en) 1980-05-30
GB2040942B (en) 1983-02-16
PT70720A (en) 1980-02-01
ATA53179A (de) 1981-10-15
NL8000337A (nl) 1980-07-29
IT1127336B (it) 1986-05-21
US4267321A (en) 1981-05-12
ES494480A0 (es) 1981-09-01
JPH02167289A (ja) 1990-06-27
DK19780A (da) 1980-07-26
FR2447381B1 (ja) 1983-05-20
ES8106736A1 (es) 1981-09-01
SE451136B (sv) 1987-09-07
AU5478080A (en) 1980-07-31
IL59202A (en) 1983-03-31
ES487955A0 (es) 1980-12-16
DK160050C (da) 1991-06-10
PH24354A (en) 1990-06-13
BE881309A (fr) 1980-07-23
FR2447381A1 (fr) 1980-08-22
AT367060B (de) 1982-05-25
US4322526A (en) 1982-03-30
JPH0212953B2 (ja) 1990-03-30

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