BR9808911B1 - métodos para melhorar a manutenção da membrana e supressão da lise de um concentrado de plaquetas (pc), para esterilizar substancialmente um pc, para o tratamento de um pc e para melhorar a manutenção de membrana e suprimir a lise de um pc. - Google Patents

métodos para melhorar a manutenção da membrana e supressão da lise de um concentrado de plaquetas (pc), para esterilizar substancialmente um pc, para o tratamento de um pc e para melhorar a manutenção de membrana e suprimir a lise de um pc.

Info

Publication number
BR9808911B1
BR9808911B1 BRPI9808911-0A BR9808911A BR9808911B1 BR 9808911 B1 BR9808911 B1 BR 9808911B1 BR 9808911 A BR9808911 A BR 9808911A BR 9808911 B1 BR9808911 B1 BR 9808911B1
Authority
BR
Brazil
Prior art keywords
lysis
membrane maintenance
improving membrane
suppression
suppressing
Prior art date
Application number
BRPI9808911-0A
Other languages
English (en)
Portuguese (pt)
Other versions
BR9808911A (pt
Inventor
Secondo Dottori
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR9808911A publication Critical patent/BR9808911A/pt
Publication of BR9808911B1 publication Critical patent/BR9808911B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08Radiation
    • A61L2/10Ultraviolet [UV] radiation
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08Radiation
    • A61L2/081Gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials
    • A61L2103/09Blood or products thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Packages (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
BRPI9808911-0A 1997-04-16 1998-04-15 métodos para melhorar a manutenção da membrana e supressão da lise de um concentrado de plaquetas (pc), para esterilizar substancialmente um pc, para o tratamento de um pc e para melhorar a manutenção de membrana e suprimir a lise de um pc. BR9808911B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/840,765 US6482585B2 (en) 1997-04-16 1997-04-16 Storage and maintenance of blood products including red blood cells and platelets
PCT/IT1998/000086 WO1998046073A1 (en) 1997-04-16 1998-04-15 Improved storage and maintenance of blood products

Publications (2)

Publication Number Publication Date
BR9808911A BR9808911A (pt) 2000-08-01
BR9808911B1 true BR9808911B1 (pt) 2010-09-21

Family

ID=25283169

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9808911-0A BR9808911B1 (pt) 1997-04-16 1998-04-15 métodos para melhorar a manutenção da membrana e supressão da lise de um concentrado de plaquetas (pc), para esterilizar substancialmente um pc, para o tratamento de um pc e para melhorar a manutenção de membrana e suprimir a lise de um pc.

Country Status (20)

Country Link
US (2) US6482585B2 (https=)
EP (1) EP0975214B1 (https=)
JP (1) JP4467649B2 (https=)
KR (1) KR100508408B1 (https=)
CN (2) CN1698430A (https=)
AT (1) ATE257326T1 (https=)
AU (1) AU739842B2 (https=)
BR (1) BR9808911B1 (https=)
CA (1) CA2286721A1 (https=)
CZ (1) CZ298671B6 (https=)
DE (1) DE69821002T2 (https=)
DK (1) DK0975214T3 (https=)
ES (1) ES2212288T3 (https=)
HU (1) HUP0001936A3 (https=)
IL (1) IL132271A (https=)
NZ (1) NZ500534A (https=)
PL (1) PL192684B1 (https=)
PT (1) PT975214E (https=)
SK (1) SK284688B6 (https=)
WO (1) WO1998046073A1 (https=)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
US6403124B1 (en) * 1997-04-16 2002-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
JP4638106B2 (ja) * 1999-10-11 2011-02-23 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 医薬的使用のための溶液中における浸透圧剤としての、l−カルニチンおよびそのアルカノイル誘導体の使用
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
RU2245145C1 (ru) * 2003-10-01 2005-01-27 Российский государственный медицинский университет Средство нормализации агрегационных свойств тромбоцитов и эритроцитов и морфоденситометрических характеристик эритроцитов
DE602004031033D1 (de) * 2003-10-09 2011-02-24 Core Dynamics Ltd Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpel
WO2005072523A2 (en) * 2004-02-02 2005-08-11 I.M.T. Interface Multigrad Technology Ltd. Biological material and methods and solutions for preservation thereof
US8196416B2 (en) * 2004-02-02 2012-06-12 Core Dynamics Limited Device for directional cooling of biological matter
ATE460947T1 (de) * 2004-06-07 2010-04-15 Core Dynamics Ltd Verfahren zur sterilisation von biologischen präparaten
EP1778007A1 (en) * 2004-08-12 2007-05-02 I.M.T. Interface Multigrad Technology Ltd. Method and apparatus for freezing or thawing of a biological material
EP1850661A2 (en) * 2005-02-22 2007-11-07 Interface Multigrad Technology (IMT) Ltd. Preserved viable cartilage, method for its preservation, and system and devices used therefor
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
EP1909565A2 (en) * 2005-08-03 2008-04-16 Interface Multigrad Technology (IMT) Ltd. Somatic cells for use in cell therapy
US7462485B2 (en) * 2005-10-07 2008-12-09 Glaser Lawrence F Modified erythrocytes and uses thereof
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
US20090202978A1 (en) * 2008-02-13 2009-08-13 Ginadi Shaham Method and apparatus for freezing of a biological material
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CA2781874A1 (en) 2009-10-12 2011-04-21 New Health Sciences, Inc. Oxygen depletion devices and methods for removing oxygen from red blood cells
JP6199557B2 (ja) 2009-10-12 2017-09-20 ニュー ヘルス サイエンシーズ、インク.New Health Sciences, Inc. 酸素及び二酸化炭素の減損能力をもつ血液保存袋システム及び減損装置
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
ES2959120T3 (es) 2010-08-25 2024-02-20 Hemanext Inc Método para potenciar la calidad y la supervivencia de glóbulos rojos durante el almacenamiento
PT2635114T (pt) 2010-11-05 2020-06-16 New Health Sciences Inc Irradiação de glóbulos vermelhos e armazenamento anaeróbico
US8512942B2 (en) 2010-11-29 2013-08-20 New York Blood Center, Inc. Method of blood pooling and storage
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
US9402866B2 (en) 2011-04-07 2016-08-02 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
AU2012279043B2 (en) * 2011-07-05 2016-07-07 Hemanext Inc. A system for extended storage of red blood cells and methods of use
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
EP2961269B1 (en) 2013-02-28 2021-09-15 Hemanext Inc. Gas depletion device for blood products
KR102701691B1 (ko) 2015-03-10 2024-08-30 헤마넥스트 인코포레이티드 산소 감소 1회용 키트, 장치 및 이의 사용 방법
KR20250126858A (ko) 2015-04-23 2025-08-25 헤마넥스트 인코포레이티드 혐기성 혈액 저장 용기
IL289099B2 (en) 2015-05-18 2024-04-01 Hemanext Inc Methods for the storage of whole blood, and compositions thereof
MX393877B (es) 2016-05-27 2025-03-24 Hemanext Inc Almacenamiento anaerobico de sangre y metodo de inactivacion de patogenos
DE102017218847A1 (de) 2017-10-23 2019-04-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Verbesserung der Stabilität von Blut und Blutprodukten
CN114786481A (zh) * 2019-11-29 2022-07-22 新泽西鲁特格斯州立大学 用于储存血液制品的组合物、试剂盒和方法及其使用方法
CN114729317A (zh) 2019-11-29 2022-07-08 新泽西鲁特格斯州立大学 脐带血血浆制品、组织和细胞外泌体的分离方法,其组合物及使用方法
CN116115753A (zh) * 2021-11-15 2023-05-16 上海循曜生物科技有限公司 一种新的改善血小板质量的方法
CN114600872A (zh) * 2022-04-13 2022-06-10 西安北光医学生物技术有限公司 一种细胞、组织或器官的抗损伤保存的方法及保存系统
WO2024206693A1 (en) * 2023-03-31 2024-10-03 Hemerus Medical, Llc Formulations and methods for collecting and storing blood and blood products

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3729947A (en) * 1970-12-04 1973-05-01 Alza Corp Process for storing blood platelets
US3792947A (en) * 1972-07-10 1974-02-19 A Diehl Molding apparatus
EP0083778B1 (de) * 1982-01-07 1987-11-11 Fresenius AG Aufbewahrungsbeutel
US4613322A (en) * 1982-12-08 1986-09-23 Edelson Richard Leslie Method and system for externally treating the blood
US5149682A (en) * 1987-09-11 1992-09-22 W. R. Grace & Co. -Conn. Manufacturing method for superconducting ceramics and products thereof
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
US5232844A (en) * 1990-05-15 1993-08-03 New York Blood Center Photodynamic inactivation of viruses in cell-containing compositions
US5376524A (en) 1991-04-01 1994-12-27 Thomas Jefferson University Platelet storage medium containing acetate and phosphate
IT1261695B (it) * 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
AU6267496A (en) * 1995-06-07 1996-12-30 Steritech, Inc. Methods of inactivating leukocytes and inhibiting cytokine p roduction in blood products
WO1997016967A1 (en) * 1995-11-09 1997-05-15 Beth Israel Deaconess Medical Center, Inc. Compositions and methods for promoting blood component survival
IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
US6010890A (en) * 1997-04-29 2000-01-04 New York Blood Center, Inc. Method for viral inactivation and compositions for use in same

Also Published As

Publication number Publication date
US6960428B2 (en) 2005-11-01
NZ500534A (en) 2001-05-25
PL192684B1 (pl) 2006-11-30
IL132271A (en) 2005-12-18
PT975214E (pt) 2004-05-31
AU7078198A (en) 1998-11-11
DE69821002T2 (de) 2004-07-08
PL336294A1 (en) 2000-06-19
IL132271A0 (en) 2001-03-19
US20010049089A1 (en) 2001-12-06
KR20010006464A (ko) 2001-01-26
US6482585B2 (en) 2002-11-19
CZ368199A3 (cs) 2000-04-12
HUP0001936A3 (en) 2001-03-28
KR100508408B1 (ko) 2005-08-17
SK284688B6 (sk) 2005-09-08
HK1025477A1 (en) 2000-11-17
HUP0001936A2 (hu) 2000-10-28
EP0975214B1 (en) 2004-01-07
WO1998046073A1 (en) 1998-10-22
JP2001523225A (ja) 2001-11-20
DK0975214T3 (da) 2004-05-10
ATE257326T1 (de) 2004-01-15
DE69821002D1 (de) 2004-02-12
ES2212288T3 (es) 2004-07-16
CN1252687A (zh) 2000-05-10
BR9808911A (pt) 2000-08-01
US20030022228A1 (en) 2003-01-30
EP0975214A1 (en) 2000-02-02
CZ298671B6 (cs) 2007-12-19
SK142799A3 (en) 2000-05-16
JP4467649B2 (ja) 2010-05-26
CA2286721A1 (en) 1998-10-22
AU739842B2 (en) 2001-10-18
CN1698430A (zh) 2005-11-23

Similar Documents

Publication Publication Date Title
BR9808911B1 (pt) métodos para melhorar a manutenção da membrana e supressão da lise de um concentrado de plaquetas (pc), para esterilizar substancialmente um pc, para o tratamento de um pc e para melhorar a manutenção de membrana e suprimir a lise de um pc.
PT1187530E (pt) Armazenamento e manutencao melhorados de produtos sanguineos incluindo globulos vermelhos e plaquetas
DE69328777D1 (de) Dekontaminierung von Plättchen mit 8-Methoxypsoralen
CA2141803A1 (en) Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen
ATE76573T1 (de) Biologisch vertraegliche implantierbare behaelter auf basis von kollagen, die die konservierung und/oder die kultivierung von zellen und/oder die kontrollierte freigabe von aktivsubstanzen ermoeglicht.
ATE262900T1 (de) Therapeutische und lebensmittel-zusammensetzungen,welche essentielle fettsäuren und bioaktive disulfide enthalten
BR9906622A (pt) Método e aparelho para inativação decontaminantes biológicos utilizandofotossensibilizadores
US20030228564A1 (en) Nitric oxide in a pathogen inactivation process
DE69432832D1 (de) Vorrichtung und verfahren zur photoaktivierung
ATE92343T1 (de) Sterilisation von behaeltern mittels wasserstoffperoxid, persaeuren und uv-strahlung.
DE3683333D1 (de) Mittel zur behandlung von akne vulgaris und deren herstellung.
US7220747B2 (en) Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
WO2003066109A1 (en) Nitric oxide in a pathogen inactivation process
EP0214017A3 (en) Use of n,n,-dimethylbiguanid p-chorophenoxyacetate in the treatment of neuropathies and nerval degeneration
RU2077890C1 (ru) Средство для стерилизации и отмывания от биологических жидкостей
SE7906037L (sv) Sterilisationssystem
CA2483046A1 (en) Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
JPH0623022A (ja) 高電圧瞬間滅菌法

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/09/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 16A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2259 DE 22-04-2014 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.