BR9808068A - Processo in vitro para eliminar células tumorosas de uma população de células que inclui células não-tumorosas, para enriquecerr o número de células germinativas numa população de células hematopoéticas, para preparar células hematopoéticas isoladas para reintrodução num paciente, para a eliminação de uma primeira população de células de uma segunda população de células, e, processo de eliminação de células tumorosas de uma população de células que inclui células não-tumorosas - Google Patents

Processo in vitro para eliminar células tumorosas de uma população de células que inclui células não-tumorosas, para enriquecerr o número de células germinativas numa população de células hematopoéticas, para preparar células hematopoéticas isoladas para reintrodução num paciente, para a eliminação de uma primeira população de células de uma segunda população de células, e, processo de eliminação de células tumorosas de uma população de células que inclui células não-tumorosas

Info

Publication number
BR9808068A
BR9808068A BR9808068-7A BR9808068A BR9808068A BR 9808068 A BR9808068 A BR 9808068A BR 9808068 A BR9808068 A BR 9808068A BR 9808068 A BR9808068 A BR 9808068A
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Brazil
Prior art keywords
cells
cell population
tumor cells
population
includes non
Prior art date
Application number
BR9808068-7A
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English (en)
Inventor
Bernhard O Palsson
Original Assignee
Bernhard O Palsson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bernhard O Palsson filed Critical Bernhard O Palsson
Publication of BR9808068A publication Critical patent/BR9808068A/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0088—Inverse microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Multimedia (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Developmental Biology & Embryology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

PROCESSO IN VITRO PARA ELIMINAR CéLULAS TUMOROSAS DE UMA POPULAçãO DE CéLULAS QUE INCLUI CéLULAS NãO-TUMOROSAS, PARA ENRIQUECER O NúMERO DE CéLULAS GERMINATIVAS NUMA POPULAçãO DE CéLULAS HEMATOPOéTICAS, PARA PREPARAR CéLULAS HERMATOPOéTICAS ISOLADAS PARA REINTRODUçãO NUM PACIENTE, PARA A ELIMINAçãO DE UMA PRIMEIRA POPULAçãO DE CéLULAS DE UMA SEGUNDA POPULAçãO DE CéLULAS, E, PROCESSO DE ELIMINAçãO DE CéLULAS TUMOROSAS DE UMA POPULAçãO DE CéLULAS QUE INCLUI CéLULAS NãO-TUMOROSAS". Apresenta-se um processo para remover células tumorosas contaminadoras de uma população de células. O processo inclui marcar as células tumorosas individuais na população e, então, matá-las com um feixe de laser de alta energia. O laser é localizado de tal forma que mate especificamente a célula tumorosa identificada, porém não as células remanescentes na população.
BR9808068-7A 1997-03-27 1998-03-27 Processo in vitro para eliminar células tumorosas de uma população de células que inclui células não-tumorosas, para enriquecerr o número de células germinativas numa população de células hematopoéticas, para preparar células hematopoéticas isoladas para reintrodução num paciente, para a eliminação de uma primeira população de células de uma segunda população de células, e, processo de eliminação de células tumorosas de uma população de células que inclui células não-tumorosas BR9808068A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/824,968 US5874266A (en) 1997-03-27 1997-03-27 Targeted system for removing tumor cells from cell populations
PCT/US1998/006125 WO1998042356A1 (en) 1997-03-27 1998-03-27 Targeted system for removing tumor cells from cell populations

Publications (1)

Publication Number Publication Date
BR9808068A true BR9808068A (pt) 2000-03-08

Family

ID=25242769

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808068-7A BR9808068A (pt) 1997-03-27 1998-03-27 Processo in vitro para eliminar células tumorosas de uma população de células que inclui células não-tumorosas, para enriquecerr o número de células germinativas numa população de células hematopoéticas, para preparar células hematopoéticas isoladas para reintrodução num paciente, para a eliminação de uma primeira população de células de uma segunda população de células, e, processo de eliminação de células tumorosas de uma população de células que inclui células não-tumorosas

Country Status (11)

Country Link
US (3) US5874266A (pt)
EP (1) EP1011697B1 (pt)
JP (2) JP4512206B2 (pt)
KR (1) KR20000075758A (pt)
CN (1) CN1251528A (pt)
AT (1) ATE349220T1 (pt)
AU (1) AU743239B2 (pt)
BR (1) BR9808068A (pt)
CA (1) CA2281112A1 (pt)
DE (1) DE69836747T2 (pt)
WO (1) WO1998042356A1 (pt)

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AU6782698A (en) 1998-10-20
ATE349220T1 (de) 2007-01-15
EP1011697B1 (en) 2006-12-27
CN1251528A (zh) 2000-04-26
AU743239B2 (en) 2002-01-24
DE69836747D1 (de) 2007-02-08
JP2010029193A (ja) 2010-02-12
US7129070B2 (en) 2006-10-31
JP4512206B2 (ja) 2010-07-28
KR20000075758A (ko) 2000-12-26
EP1011697A4 (en) 2002-11-20
US6143535A (en) 2000-11-07
JP2002511843A (ja) 2002-04-16
EP1011697A1 (en) 2000-06-28
US5874266A (en) 1999-02-23
WO1998042356A1 (en) 1998-10-01
CA2281112A1 (en) 1998-10-01
DE69836747T2 (de) 2007-10-04
US20030138923A1 (en) 2003-07-24

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