DE69737684D1 - Präzise wirksamkeitsbestimmungsmethode für wirkstoffe einschliesslich chemotherapeutika - Google Patents
Präzise wirksamkeitsbestimmungsmethode für wirkstoffe einschliesslich chemotherapeutikaInfo
- Publication number
- DE69737684D1 DE69737684D1 DE69737684T DE69737684T DE69737684D1 DE 69737684 D1 DE69737684 D1 DE 69737684D1 DE 69737684 T DE69737684 T DE 69737684T DE 69737684 T DE69737684 T DE 69737684T DE 69737684 D1 DE69737684 D1 DE 69737684D1
- Authority
- DE
- Germany
- Prior art keywords
- active substances
- determination method
- substances including
- efficacy determination
- including chemotherapeutics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000004748 cultured cell Anatomy 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/679,056 US5728541A (en) | 1996-07-12 | 1996-07-12 | Method for preparing cell cultures from biologial specimens for chemotherapeutic and other assays |
| US679056 | 1996-07-12 | ||
| PCT/US1997/011595 WO1998002038A1 (en) | 1996-07-12 | 1997-07-10 | Precise efficacy assay methods for active agents including chemotherapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69737684D1 true DE69737684D1 (de) | 2007-06-14 |
| DE69737684T2 DE69737684T2 (de) | 2008-01-31 |
Family
ID=24725407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69737684T Expired - Lifetime DE69737684T2 (de) | 1996-07-12 | 1997-07-10 | Präzise wirksamkeitsbestimmungsmethode für wirkstoffe einschliesslich chemotherapeutika |
Country Status (13)
| Country | Link |
|---|---|
| US (13) | US5728541A (de) |
| EP (1) | EP0912085B1 (de) |
| JP (1) | JP4108128B2 (de) |
| CN (1) | CN1143618C (de) |
| AT (1) | ATE360989T1 (de) |
| AU (1) | AU712302B2 (de) |
| BR (1) | BR9710348A (de) |
| CA (1) | CA2259984C (de) |
| DE (1) | DE69737684T2 (de) |
| ES (1) | ES2283022T3 (de) |
| IL (1) | IL127964A (de) |
| NZ (1) | NZ333830A (de) |
| WO (1) | WO1998002038A1 (de) |
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| US20040023375A1 (en) * | 2002-07-30 | 2004-02-05 | Precision Therapeutics, Inc. | Method for preparing cell cultures from biological specimens for chemotherapeutic and other assays |
| US6171780B1 (en) | 1997-06-02 | 2001-01-09 | Aurora Biosciences Corporation | Low fluorescence assay platforms and related methods for drug discovery |
| US6517781B1 (en) * | 1997-06-02 | 2003-02-11 | Aurora Biosciences Corporation | Low fluorescence assay platforms and related methods for drug discovery |
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| US20040086888A1 (en) * | 2001-10-18 | 2004-05-06 | Kornblith Paul L | Method for tandem genomic/proteomic analysis of proliferating cells |
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| WO2011008990A1 (en) | 2009-07-15 | 2011-01-20 | Prometheus Laboratories Inc. | Drug selection for gastric cancer therapy using antibody-based arrays |
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| US9931105B2 (en) | 2008-12-16 | 2018-04-03 | Nico Corporation | System and method of taking and collecting tissue cores for treatment |
| US8430825B2 (en) | 2008-12-16 | 2013-04-30 | Nico Corporation | Tissue removal device for neurosurgical and spinal surgery applications |
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| US10080578B2 (en) | 2008-12-16 | 2018-09-25 | Nico Corporation | Tissue removal device with adjustable delivery sleeve for neurosurgical and spinal surgery applications |
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| US20040086888A1 (en) | 2001-10-18 | 2004-05-06 | Kornblith Paul L | Method for tandem genomic/proteomic analysis of proliferating cells |
| EP1453383A4 (de) * | 2001-11-13 | 2004-12-22 | Einstein Coll Med | Neues saitohin-gen und seine verwendung |
| US6900017B2 (en) * | 2002-01-10 | 2005-05-31 | The Board Of Trustees Of The University Of Illinois | Human hematopoietic growth regulatory gene and uses |
| JP4175215B2 (ja) * | 2003-08-08 | 2008-11-05 | 日産自動車株式会社 | バイポーラ電池、組電池、複合組電池、および組電池または複合組電池を用いた車両 |
| EP1846039A2 (de) * | 2005-01-10 | 2007-10-24 | Research Development Foundation | Gezielte chimärische moleküle zur krebstherapie |
| CA2620936A1 (en) * | 2005-09-01 | 2007-03-08 | Precision Therapeutics, Inc. | Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics |
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1996
- 1996-07-12 US US08/679,056 patent/US5728541A/en not_active Expired - Lifetime
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1997
- 1997-07-10 ES ES97933267T patent/ES2283022T3/es not_active Expired - Lifetime
- 1997-07-10 AU AU36493/97A patent/AU712302B2/en not_active Ceased
- 1997-07-10 CA CA002259984A patent/CA2259984C/en not_active Expired - Lifetime
- 1997-07-10 WO PCT/US1997/011595 patent/WO1998002038A1/en not_active Ceased
- 1997-07-10 AT AT97933267T patent/ATE360989T1/de not_active IP Right Cessation
- 1997-07-10 EP EP97933267A patent/EP0912085B1/de not_active Expired - Lifetime
- 1997-07-10 NZ NZ333830A patent/NZ333830A/xx unknown
- 1997-07-10 BR BR9710348-9A patent/BR9710348A/pt not_active Application Discontinuation
- 1997-07-10 CN CNB971961433A patent/CN1143618C/zh not_active Expired - Fee Related
- 1997-07-10 IL IL12796497A patent/IL127964A/en not_active IP Right Cessation
- 1997-07-10 JP JP50606998A patent/JP4108128B2/ja not_active Expired - Fee Related
- 1997-07-10 DE DE69737684T patent/DE69737684T2/de not_active Expired - Lifetime
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1998
- 1998-03-16 US US09/039,957 patent/US6933129B1/en not_active Expired - Lifetime
- 1998-03-17 US US09/040,161 patent/US6900027B1/en not_active Expired - Lifetime
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2002
- 2002-07-26 US US10/205,887 patent/US6887680B2/en not_active Expired - Lifetime
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2005
- 2005-03-08 US US11/073,931 patent/US7112415B2/en not_active Expired - Lifetime
- 2005-03-17 US US11/081,827 patent/US7314731B2/en not_active Expired - Fee Related
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2006
- 2006-08-15 US US11/504,098 patent/US7563593B2/en not_active Expired - Fee Related
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2007
- 2007-11-26 US US11/944,884 patent/US7501260B2/en not_active Expired - Fee Related
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2008
- 2008-09-10 US US12/208,076 patent/US7678552B2/en not_active Expired - Fee Related
- 2008-10-02 US US12/244,463 patent/US7771963B2/en not_active Expired - Fee Related
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2010
- 2010-01-20 US US12/690,529 patent/US8183009B2/en not_active Expired - Fee Related
- 2010-07-01 US US12/828,665 patent/US8058025B2/en not_active Expired - Fee Related
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2011
- 2011-10-06 US US13/267,581 patent/US20120088264A1/en not_active Abandoned
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