BR9803968A - Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento. - Google Patents
Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento.Info
- Publication number
- BR9803968A BR9803968A BR9803968-7A BR9803968A BR9803968A BR 9803968 A BR9803968 A BR 9803968A BR 9803968 A BR9803968 A BR 9803968A BR 9803968 A BR9803968 A BR 9803968A
- Authority
- BR
- Brazil
- Prior art keywords
- medicine
- preparation
- ischemic
- biphenylsulfonylcyanamides
- induced
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- CBTRBYGUVACZIU-UHFFFAOYSA-N n-cyano-2-phenylbenzenesulfonamide Chemical class N#CNS(=O)(=O)C1=CC=CC=C1C1=CC=CC=C1 CBTRBYGUVACZIU-UHFFFAOYSA-N 0.000 title 1
- 230000000302 ischemic effect Effects 0.000 abstract 2
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003293 cardioprotective effect Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000035778 pathophysiological process Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"BIFENILSULFONILCIANAMIDAS, PROCESSO PARA SUA PREPARAçãO E SEU USO COMO MEDICAMENTO"<D>. Os compostos da fórmula I nos quais os símbolos apresentam os significados indicados nas reivindicações e que apresentam propriedades antiarrítmicas convenientes. Eles exibem um componente cardioprotetor. Eles podem inibir ou diminuir bastante, de um modo preventivo, os procesos patofisiológicos na formação de danos induzidos isquemicamente, particularmente na eliciação de arritmias cardíacas induzidas isquemicamente. Além do mais, eles apresentam uma ação inibitória forte na proliferação de células.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19741635A DE19741635A1 (de) | 1997-09-22 | 1997-09-22 | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9803968A true BR9803968A (pt) | 2000-05-02 |
Family
ID=7843124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9803968-7A BR9803968A (pt) | 1997-09-22 | 1998-09-21 | Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5968978A (pt) |
EP (1) | EP0903339B1 (pt) |
JP (1) | JP4272278B2 (pt) |
KR (1) | KR19990029983A (pt) |
CN (2) | CN1212255A (pt) |
AR (1) | AR015170A1 (pt) |
AT (1) | ATE210638T1 (pt) |
AU (1) | AU755553B2 (pt) |
BR (1) | BR9803968A (pt) |
CA (1) | CA2247749A1 (pt) |
CZ (1) | CZ300698A3 (pt) |
DE (2) | DE19741635A1 (pt) |
DK (1) | DK0903339T3 (pt) |
ES (1) | ES2169467T3 (pt) |
HK (1) | HK1040980A1 (pt) |
HU (1) | HUP9802132A3 (pt) |
PL (1) | PL328762A1 (pt) |
PT (1) | PT903339E (pt) |
TR (1) | TR199801871A2 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19737224A1 (de) * | 1997-08-27 | 1999-03-18 | Hoechst Marion Roussel De Gmbh | Pharmazeutisches Kombinationspräparat aus einem Inhibitor des Natrium-Wasserstoff-Austauschers und einem Arzneimittel zur Behandlung von Herz-Kreislauferkrankungen |
DE19804251A1 (de) | 1998-02-04 | 1999-08-05 | Hoechst Marion Roussel De Gmbh | Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
BR9908474A (pt) * | 1998-03-04 | 2000-12-05 | Takeda Chemical Industries Ltd | Preparação de liberação prolongada, processo para a produção de uma preparação de liberação prolongada, e, composição farmacêutica |
DE19820064A1 (de) * | 1998-05-06 | 1999-11-11 | Hoechst Marion Roussel De Gmbh | Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
HUP0103000A3 (en) * | 1998-07-20 | 2002-08-28 | Smithkline Beecham Corp | Bioenhanced formulations comprising eprosartan in oral solid dosage form and process for their preparation |
DE10018401A1 (de) * | 2000-04-13 | 2001-10-25 | Boehringer Ingelheim Pharma | Verwendung von Bradycardica bei der Behandlung von mit Hypertrophie einhergehenden Myocarderkrankungen und neue Arzneimittelkombinationen |
US20070160645A1 (en) * | 2001-10-25 | 2007-07-12 | Jakob Vinten-Johansen | PostConditioning System And Method For The Reduction Of Ischemic-Reperfusion Injury In The Heart And Other Organs |
DE60229416D1 (de) | 2001-10-25 | 2008-11-27 | Univ Emory | Katheter für modifizierte Perfusion |
DE10206354A1 (de) * | 2002-02-14 | 2003-08-28 | Aventis Pharma Gmbh | Verwendung von Inhibitoren des Natrium-abhängigen Chlorid-Bicarbonat-Austauschers zur Behandlung von thrombotischen und inflammatorischer Erkrankungen |
US20040138306A1 (en) * | 2002-07-25 | 2004-07-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of a specific cyclic amine derivative or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure |
US20060099230A1 (en) * | 2004-11-10 | 2006-05-11 | Chin-Chih Chiang | Novel formulations of eprosartan with enhanced bioavailability |
JP2008525468A (ja) * | 2004-12-22 | 2008-07-17 | エモリー・ユニバーシティ | ポストコンディショニング臓器保護作用を増強する治療補助薬 |
EP1762179A1 (en) * | 2005-09-07 | 2007-03-14 | Boehringer Ingelheim Vetmedica Gmbh | Method for improving diagnostic quality in echocardiography |
US7541492B2 (en) * | 2005-10-26 | 2009-06-02 | Toyota Jidosha Kabushiki Kaisha | Perfluoroalkanesulfonamide compounds |
RU2014109079A (ru) | 2011-08-12 | 2015-09-20 | Бёрингер Ингельхайм Ветмедика Гмбх | Фармацевтическая композиция с маскированным вкусом |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
CN113527152B (zh) * | 2021-08-09 | 2023-07-28 | 西北农林科技大学 | 一种联苯磺酰胺类化合物及其防治农作物害虫的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2533127A1 (de) * | 1975-07-24 | 1977-02-10 | Bayer Ag | Polytriazine und ein verfahren zu deren herstellung |
DE2533126A1 (de) * | 1975-07-24 | 1977-02-10 | Bayer Ag | Polytriazine und ein verfahren zu deren herstellung |
CA2062558A1 (en) * | 1991-03-08 | 1992-09-09 | Prasun K. Chakravarty | Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists |
EP0503838A3 (en) * | 1991-03-08 | 1992-10-07 | Merck & Co. Inc. | Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists |
EP0586513A1 (en) * | 1991-05-10 | 1994-03-16 | Merck & Co. Inc. | Acidic aralkyl triazole derivatives active as angiotensin ii antagonists |
EP0855392A3 (de) * | 1997-01-22 | 2000-01-05 | Hoechst Aktiengesellschaft | Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1997
- 1997-09-22 DE DE19741635A patent/DE19741635A1/de not_active Withdrawn
-
1998
- 1998-09-16 DK DK98117529T patent/DK0903339T3/da active
- 1998-09-16 DE DE59802412T patent/DE59802412D1/de not_active Expired - Lifetime
- 1998-09-16 EP EP98117529A patent/EP0903339B1/de not_active Expired - Lifetime
- 1998-09-16 ES ES98117529T patent/ES2169467T3/es not_active Expired - Lifetime
- 1998-09-16 AT AT98117529T patent/ATE210638T1/de not_active IP Right Cessation
- 1998-09-16 PT PT98117529T patent/PT903339E/pt unknown
- 1998-09-18 AR ARP980104685A patent/AR015170A1/es unknown
- 1998-09-18 CZ CZ983006A patent/CZ300698A3/cs unknown
- 1998-09-21 US US09/157,589 patent/US5968978A/en not_active Expired - Lifetime
- 1998-09-21 KR KR1019980038932A patent/KR19990029983A/ko not_active Application Discontinuation
- 1998-09-21 BR BR9803968-7A patent/BR9803968A/pt not_active IP Right Cessation
- 1998-09-21 TR TR1998/01871A patent/TR199801871A2/xx unknown
- 1998-09-21 CA CA002247749A patent/CA2247749A1/en not_active Abandoned
- 1998-09-21 AU AU86108/98A patent/AU755553B2/en not_active Ceased
- 1998-09-21 JP JP26685098A patent/JP4272278B2/ja not_active Expired - Fee Related
- 1998-09-22 PL PL98328762A patent/PL328762A1/xx unknown
- 1998-09-22 CN CN98119536A patent/CN1212255A/zh active Pending
- 1998-09-22 HU HU9802132A patent/HUP9802132A3/hu unknown
-
2000
- 2000-02-25 CN CN00102661A patent/CN1326928A/zh active Pending
-
2002
- 2002-04-03 HK HK02102461.4A patent/HK1040980A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
HUP9802132A2 (hu) | 2000-02-28 |
CN1326928A (zh) | 2001-12-19 |
EP0903339A2 (de) | 1999-03-24 |
PL328762A1 (en) | 1999-03-29 |
AU755553B2 (en) | 2002-12-12 |
CN1212255A (zh) | 1999-03-31 |
EP0903339A3 (de) | 1999-03-31 |
HUP9802132A3 (en) | 2000-04-28 |
AR015170A1 (es) | 2001-04-18 |
EP0903339B1 (de) | 2001-12-12 |
CA2247749A1 (en) | 1999-03-22 |
ES2169467T3 (es) | 2002-07-01 |
KR19990029983A (ko) | 1999-04-26 |
ATE210638T1 (de) | 2001-12-15 |
AU8610898A (en) | 1999-04-01 |
DE19741635A1 (de) | 1999-03-25 |
JP4272278B2 (ja) | 2009-06-03 |
TR199801871A3 (tr) | 1999-04-21 |
HU9802132D0 (en) | 1998-11-30 |
CZ300698A3 (cs) | 1999-04-14 |
TR199801871A2 (xx) | 1999-04-21 |
HK1040980A1 (zh) | 2002-06-28 |
PT903339E (pt) | 2002-06-28 |
DE59802412D1 (de) | 2002-01-24 |
US5968978A (en) | 1999-10-19 |
JPH11189581A (ja) | 1999-07-13 |
DK0903339T3 (da) | 2002-04-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TC | Change of name | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1861 DE 05/09/2006. |