KR950031059A - 골다공증 치료용 약제학적 조성물 - Google Patents
골다공증 치료용 약제학적 조성물 Download PDFInfo
- Publication number
- KR950031059A KR950031059A KR1019950008333A KR19950008333A KR950031059A KR 950031059 A KR950031059 A KR 950031059A KR 1019950008333 A KR1019950008333 A KR 1019950008333A KR 19950008333 A KR19950008333 A KR 19950008333A KR 950031059 A KR950031059 A KR 950031059A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical composition
- active ingredient
- treating osteoporosis
- osteoporosis according
- isoadfumulon
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
본 발명은 활성 성분으로서 후물론, 코후물론, 애드후물론, 이소후물론, 이소코후물론, 및 이소애드후물론을 포함하는 그룹으로부터 선택된 하나 이상의 화합물 유효량과 약제학적으로 허용되는 담체 또는 부형제와의 배합물을 포함하는 골다공증 치료용 약제학적 조성물에 관한 것이다. 후물론, 코후물론, 애드후물론은 홉스로부터 추출된 성분인 α산에 속하는 화합물인 반면, 이소후물론, 이소코후물론 및 이소애드후물론은 α산의 이성체인 이소α산 유도체에 속하는 화합물이다.
상술한 화합물은 골 재흡수 억제 활성을 갖고 골다공증 치료에 유용하다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (11)
- 활성 성분으로서 후물론, 코후물론, 애드후물론, 이소후물론, 이소코후물론 및 이소애드후물론을 포함하는 그룹으로부터 선택된 하나 이상의 화합물 유효량과 약제학적으로 허용되는 담체 또는 부형제와의 배합물을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 코후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 애드후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 이소후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 이소코후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 이소애드후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 후물론, 코후물론, 애드후물론, 이소후물론, 이소코후물론 및 이소애드후물론의 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 홉스(hops)로부터 추출하여 수득한 후물론, 코후물론, 애드후물론, 이소후물론, 이소코후물론, 및 이소애드후물론의 혼합물을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 홉스로부터 추출하여 수득한 후물론, 코후물론 및 애드후물론을 포함하는 골다공증 치료용 약제학적 조성물.
- 제1항에 있어서, 활성 성분으로서 홉스로부터 추출하여 수득한 이소후물론, 이소코후물론, 및 이소애드후물론을 혼합물을 포함하는 골다공증 치료용 약제학적 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7323094 | 1994-04-12 | ||
JP94-073230 | 1994-04-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR950031059A true KR950031059A (ko) | 1995-12-18 |
Family
ID=13512179
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950008333A KR950031059A (ko) | 1994-04-12 | 1995-04-11 | 골다공증 치료용 약제학적 조성물 |
Country Status (13)
Country | Link |
---|---|
US (1) | US5604263A (ko) |
EP (1) | EP0677289B1 (ko) |
KR (1) | KR950031059A (ko) |
AT (1) | ATE175575T1 (ko) |
AU (1) | AU696334B2 (ko) |
CA (1) | CA2146820A1 (ko) |
DE (1) | DE69507185T2 (ko) |
DK (1) | DK0677289T3 (ko) |
ES (1) | ES2129691T3 (ko) |
FI (1) | FI951702A (ko) |
HU (1) | HUT71604A (ko) |
NO (1) | NO951422L (ko) |
TW (1) | TW427901B (ko) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7901714B2 (en) * | 2001-06-20 | 2011-03-08 | Metaproteomics, Llp | Treatment modalities for autoimmune diseases |
US7718198B2 (en) * | 2001-06-20 | 2010-05-18 | Metaproteomics, Llc | Treatment modalities for autoimmune diseases |
US7901713B2 (en) * | 2001-06-20 | 2011-03-08 | Metaproteomics, Llc | Inhibition of COX-2 and/or 5-LOX activity by fractions isolated or derived from hops |
US8168234B2 (en) * | 2001-06-20 | 2012-05-01 | Metaproteomics, Llc | Compositions that treat or inhibit pathological conditions associated with inflammatory response |
US20040115290A1 (en) | 2001-06-20 | 2004-06-17 | Tripp Matthew L. | Modulation of inflammation by hops fractions and derivatives |
US7666449B2 (en) * | 2001-06-20 | 2010-02-23 | Metaproteomics, Llc | Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity |
US20040219240A1 (en) * | 2001-06-20 | 2004-11-04 | Babish John G. | Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity |
US8142819B2 (en) | 2002-10-21 | 2012-03-27 | Metaproteomics, Llc | Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response |
US7205151B2 (en) * | 2001-06-20 | 2007-04-17 | Metaproteomics, Llc | Complex mixtures exhibiting selective inhibition of cyclooxygenase-2 |
US8206753B2 (en) * | 2001-06-20 | 2012-06-26 | Metaproteomics, Llc | Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes |
US7270835B2 (en) * | 2001-06-20 | 2007-09-18 | Metaproteomics, Llc | Compositions that treat or inhibit pathological conditions associated with inflammatory response |
US7279185B2 (en) * | 2001-10-26 | 2007-10-09 | Metaproteonics, Llc | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2 |
US20090263522A1 (en) * | 2001-10-26 | 2009-10-22 | Babish John G | Curcuminoid Compositions Exhibiting Synergistic Inhibition Of The Expression And/Or Activity Of Cyclooxygenase-2 |
US8158160B2 (en) | 2001-11-13 | 2012-04-17 | Eric Hauser Kuhrts | Anti-inflammatory cyclooxygenase inhibitors |
KR100993113B1 (ko) * | 2002-02-14 | 2010-11-08 | 기린 홀딩스 가부시키가이샤 | 지질대사 개선용 조성물 및 식품 |
WO2004037180A2 (en) * | 2002-10-21 | 2004-05-06 | Metaproteomics, Llc | Compositions that treat or inhibit pathological conditions associated with inflammatory response |
JP2005104951A (ja) * | 2003-01-17 | 2005-04-21 | Kirin Brewery Co Ltd | 血圧降下用組成物および血管柔軟性改善用組成物並びにこれらの機能が付与された食品 |
WO2005039483A2 (en) * | 2003-05-22 | 2005-05-06 | Metaproteomics, Llc | Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity |
US7914831B2 (en) * | 2004-02-27 | 2011-03-29 | Metaproteomics, Llc | Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines |
US20050192356A1 (en) * | 2004-02-27 | 2005-09-01 | Babish John G. | Synergistic anti-inflammatory pharmaceutical compositions and methods of use |
EP1928248A4 (en) * | 2005-08-09 | 2009-09-16 | Metaproteomics Llp | MODULATION OF KINASE PROTEINS USING HOP OR ACACIA PRODUCTS |
WO2007067812A2 (en) * | 2005-12-09 | 2007-06-14 | Metaproteomics, Llc | Protein kinase modulation by hops and acacia products |
EP2043621A4 (en) * | 2006-06-20 | 2009-08-26 | Metaproteomics Llc | TREATMENT OF CANCER BY MODULATION OF PROTEIN KINASE USING HEXAHYDRO-ISOALPHA ACIDS |
US20080051466A1 (en) * | 2006-06-20 | 2008-02-28 | Metaproteomics, Llc | Isoalpha acid based protein kinase modulation cancer treatment |
AU2008229110A1 (en) * | 2007-03-19 | 2008-09-25 | Metaproteomics, Llc | Methods and compositions for promoting bone and joint health |
CA2686043A1 (en) | 2007-05-11 | 2008-11-20 | Metaproteomics, Llc | Methods and compositions for heavy metal detoxification |
CN101969972A (zh) * | 2007-12-10 | 2011-02-09 | 麦特普罗泰欧米克斯有限公司 | 癌症、血管生成、以及与其相关的炎症通路的取代的1,3-环戊二酮多靶点蛋白激酶调节剂 |
US20100222262A1 (en) * | 2008-04-02 | 2010-09-02 | Metaproteomics, Llc | Substituted 1, 3-cyclopentadione attenuated endothelial inflammation and endothelial-monocyte interactions |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3892808A (en) * | 1965-11-17 | 1975-07-01 | Carlton & United Breweries | Hop extracts |
DE1901277A1 (de) * | 1969-01-10 | 1970-08-06 | Partipharm Ag | Mittel zur Kompensation uebermaessigen Zigarettenkonsums |
US5370863A (en) * | 1992-12-16 | 1994-12-06 | Miller Brewing Company | Oral care compositions containing hop acids and method |
JPH06312924A (ja) * | 1993-04-28 | 1994-11-08 | Asahi Breweries Ltd | 抗酸化作用を有するフムロン類の利用 |
-
1995
- 1995-04-06 DE DE69507185T patent/DE69507185T2/de not_active Expired - Fee Related
- 1995-04-06 AT AT95105177T patent/ATE175575T1/de not_active IP Right Cessation
- 1995-04-06 ES ES95105177T patent/ES2129691T3/es not_active Expired - Lifetime
- 1995-04-06 DK DK95105177T patent/DK0677289T3/da active
- 1995-04-06 EP EP95105177A patent/EP0677289B1/en not_active Expired - Lifetime
- 1995-04-10 FI FI951702A patent/FI951702A/fi unknown
- 1995-04-10 US US08/420,728 patent/US5604263A/en not_active Expired - Fee Related
- 1995-04-11 CA CA002146820A patent/CA2146820A1/en not_active Abandoned
- 1995-04-11 AU AU16384/95A patent/AU696334B2/en not_active Ceased
- 1995-04-11 HU HU9501043A patent/HUT71604A/hu unknown
- 1995-04-11 NO NO951422A patent/NO951422L/no not_active Application Discontinuation
- 1995-04-11 KR KR1019950008333A patent/KR950031059A/ko not_active Application Discontinuation
- 1995-05-05 TW TW084104477A patent/TW427901B/zh active
Also Published As
Publication number | Publication date |
---|---|
EP0677289A2 (en) | 1995-10-18 |
US5604263A (en) | 1997-02-18 |
CA2146820A1 (en) | 1995-10-13 |
NO951422D0 (no) | 1995-04-11 |
HU9501043D0 (en) | 1995-06-28 |
EP0677289B1 (en) | 1999-01-13 |
ES2129691T3 (es) | 1999-06-16 |
AU696334B2 (en) | 1998-09-10 |
EP0677289A3 (en) | 1996-10-23 |
TW427901B (en) | 2001-04-01 |
DE69507185T2 (de) | 1999-09-09 |
ATE175575T1 (de) | 1999-01-15 |
FI951702A0 (fi) | 1995-04-10 |
DE69507185D1 (de) | 1999-02-25 |
HUT71604A (en) | 1996-01-29 |
FI951702A (fi) | 1995-10-13 |
NO951422L (no) | 1995-10-13 |
DK0677289T3 (da) | 1999-09-06 |
AU1638495A (en) | 1995-10-19 |
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