KR950031060A - 골다공증 치료용 약제학적 조성물 - Google Patents
골다공증 치료용 약제학적 조성물 Download PDFInfo
- Publication number
- KR950031060A KR950031060A KR1019950009173A KR19950009173A KR950031060A KR 950031060 A KR950031060 A KR 950031060A KR 1019950009173 A KR1019950009173 A KR 1019950009173A KR 19950009173 A KR19950009173 A KR 19950009173A KR 950031060 A KR950031060 A KR 950031060A
- Authority
- KR
- South Korea
- Prior art keywords
- osteoporosis
- treatment
- pharmaceutical composition
- xanthohumol
- active ingredient
- Prior art date
Links
- 208000001132 Osteoporosis Diseases 0.000 title claims abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- YKGCBLWILMDSAV-GOSISDBHSA-N Isoxanthohumol Natural products O(C)c1c2C(=O)C[C@H](c3ccc(O)cc3)Oc2c(C/C=C(\C)/C)c(O)c1 YKGCBLWILMDSAV-GOSISDBHSA-N 0.000 claims abstract 3
- FUSADYLVRMROPL-UHFFFAOYSA-N demethylxanthohumol Natural products CC(C)=CCC1=C(O)C=C(O)C(C(=O)C=CC=2C=CC(O)=CC=2)=C1O FUSADYLVRMROPL-UHFFFAOYSA-N 0.000 claims abstract 3
- ORXQGKIUCDPEAJ-YRNVUSSQSA-N xanthohumol Chemical compound COC1=CC(O)=C(CC=C(C)C)C(O)=C1C(=O)\C=C\C1=CC=C(O)C=C1 ORXQGKIUCDPEAJ-YRNVUSSQSA-N 0.000 claims abstract 3
- UVBDKJHYMQEAQV-UHFFFAOYSA-N xanthohumol Natural products OC1=C(CC=C(C)C)C(OC)=CC(OC)=C1C(=O)C=CC1=CC=C(O)C=C1 UVBDKJHYMQEAQV-UHFFFAOYSA-N 0.000 claims abstract 3
- 235000008209 xanthohumol Nutrition 0.000 claims abstract 3
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000006386 Bone Resorption Diseases 0.000 abstract 1
- 230000024279 bone resorption Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
Abstract
본 발명은, 활성성분으로서 크산토휴몰을 포함하는 골다공증 치료제에 관한 것이다. 호프 추출물로부터 수득된 크산토휴몰은 골 재흡수 억제 활성을 갖고 골다공증 치료제로서 유용하다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
1. 활성성분으로서 유효량의 하기 구조식(Ⅰ)의 크산토휴몰 및 약제학적으로 허용되는 담체를 포함하는, 골다공증 치료용 약제학적 조성물.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP94-082852 | 1994-04-21 | ||
JP6082852A JPH07285856A (ja) | 1994-04-21 | 1994-04-21 | 骨粗鬆症治療剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950031060A true KR950031060A (ko) | 1995-12-18 |
KR100350564B1 KR100350564B1 (ko) | 2002-12-16 |
Family
ID=13785904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950009173A KR100350564B1 (ko) | 1994-04-21 | 1995-04-19 | 골다공증치료용약제학적조성물 |
Country Status (14)
Country | Link |
---|---|
US (1) | US5679716A (ko) |
EP (1) | EP0679393B1 (ko) |
JP (1) | JPH07285856A (ko) |
KR (1) | KR100350564B1 (ko) |
AT (1) | ATE162073T1 (ko) |
AU (1) | AU695696B2 (ko) |
CA (1) | CA2147419A1 (ko) |
DE (1) | DE69501419T2 (ko) |
DK (1) | DK0679393T3 (ko) |
ES (1) | ES2116642T3 (ko) |
FI (1) | FI951856A (ko) |
HU (1) | HUT71603A (ko) |
NO (1) | NO951498L (ko) |
TW (1) | TW284687B (ko) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6008208A (en) * | 1995-10-23 | 1999-12-28 | Osteoscreen, Inc. | Compositions and methods for treating bone deficit conditions |
US6241762B1 (en) | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
DE19939350B4 (de) * | 1999-08-19 | 2005-04-07 | Plantextrakt Gmbh & Co. Kg | Hopfenextrakt und Verfahren zu dessen Herstellung |
JP4249926B2 (ja) * | 2000-01-27 | 2009-04-08 | タカラバイオ株式会社 | 治療剤 |
WO2001076614A1 (fr) * | 2000-04-10 | 2001-10-18 | Takara Bio Inc. | Remedes |
US6352726B1 (en) * | 2001-01-09 | 2002-03-05 | S. S. Steiner, Inc. | Method of killing protozoa |
BR0208418A (pt) * | 2001-04-05 | 2004-03-30 | Unilever Nv | Uso de isoxantohumol e/ou xantohumol, método para administrar isoxantohumol e/ou xantohumol a seres humanos em necessidade de receber um componente ani-inflamatório ou anti-envelhecimento, e, produto alimentìcio |
FR2823672B1 (fr) * | 2001-04-23 | 2004-03-12 | Berkem Sa | Extraits de houblon et leur utilisation dans la preparation d'un medicament ayant des proprietes oestrogenes |
KR100993113B1 (ko) * | 2002-02-14 | 2010-11-08 | 기린 홀딩스 가부시키가이샤 | 지질대사 개선용 조성물 및 식품 |
EP1503633A1 (en) * | 2002-04-24 | 2005-02-09 | Unilever N.V. | Use of hop components in foods |
DE10240065B4 (de) * | 2002-08-30 | 2004-10-28 | Hallertauer Hopfenveredlungsgesellschaft M.B.H. | Verfahren zur Gewinnung von in Hopfen enthaltenem Xanthohumol und damit erhältlicher Xanthohumol-reicher Hopfenextrakt |
DE50302729D1 (de) * | 2002-12-18 | 2006-05-11 | Doehler Gmbh | Xanthohumol-haltiges Getränk |
US20070059393A1 (en) * | 2003-04-08 | 2007-03-15 | Kirin Beer Kabushiki Kaisha | Composition for inhibition or prevention of bone density |
DE102004063125B4 (de) * | 2004-12-22 | 2007-03-15 | Ta-Xan-Ag | Natürlicher Xanthohumol-haltiger Extrakt sowie das Verfahren zu dessen Herstellung und daraus hergestellte Getränke |
WO2007016578A2 (en) * | 2005-07-29 | 2007-02-08 | Bioactives, Inc. | Prenylflavonoid formulations |
DE102006062264A1 (de) * | 2006-12-22 | 2008-06-26 | Joh. Barth & Sohn Gmbh & Co. Kg | Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen |
EP2392325A1 (en) | 2010-06-04 | 2011-12-07 | Universitätsklinikum Münster | Compounds for the prevention and/or treatment of osteoarthrosis |
KR101323150B1 (ko) * | 2011-04-25 | 2013-10-30 | 충남대학교산학협력단 | 잔토휴몰을 함유하는 골다공증 예방 및 치료용 조성물 |
CN103371989A (zh) * | 2012-04-24 | 2013-10-30 | 华东师范大学 | 黄腐酚在制备抑制破骨细胞分化和蚀骨功能的预防和/或治疗药物中的应用 |
US9782362B2 (en) | 2012-07-26 | 2017-10-10 | Ta-Xan Ag | Uses of compositions containing a roasted extract and xanthohumol |
JP6009498B2 (ja) * | 2014-06-24 | 2016-10-19 | 国立大学法人京都大学 | アルツハイマー病予防薬 |
US20180193287A1 (en) | 2015-07-02 | 2018-07-12 | John I. Haas, Inc. | Hops-based substance and use of the substance |
CN105477686B (zh) * | 2015-11-30 | 2019-02-15 | 长春工业大学 | 一种包覆黄腐酚的纳米纤维膜 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3794744A (en) * | 1972-05-10 | 1974-02-26 | White Tomkins Ltd | Purification of hop extracts |
US4065574A (en) * | 1975-08-29 | 1977-12-27 | The Upjohn Company | New method for controlling fungi using 4-chromone, 4-chromanone, 4-chromone oxime and 4-chromanone oxime compounds |
-
1994
- 1994-04-21 JP JP6082852A patent/JPH07285856A/ja active Pending
-
1995
- 1995-04-18 AT AT95105766T patent/ATE162073T1/de not_active IP Right Cessation
- 1995-04-18 DK DK95105766T patent/DK0679393T3/da active
- 1995-04-18 EP EP95105766A patent/EP0679393B1/en not_active Expired - Lifetime
- 1995-04-18 DE DE69501419T patent/DE69501419T2/de not_active Expired - Fee Related
- 1995-04-18 ES ES95105766T patent/ES2116642T3/es not_active Expired - Lifetime
- 1995-04-19 KR KR1019950009173A patent/KR100350564B1/ko not_active IP Right Cessation
- 1995-04-19 FI FI951856A patent/FI951856A/fi unknown
- 1995-04-19 AU AU16535/95A patent/AU695696B2/en not_active Ceased
- 1995-04-20 HU HU9501121A patent/HUT71603A/hu unknown
- 1995-04-20 CA CA002147419A patent/CA2147419A1/en not_active Abandoned
- 1995-04-20 NO NO951498A patent/NO951498L/no not_active Application Discontinuation
- 1995-05-10 TW TW084104612A patent/TW284687B/zh active
-
1996
- 1996-09-27 US US08/720,004 patent/US5679716A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0679393A2 (en) | 1995-11-02 |
ATE162073T1 (de) | 1998-01-15 |
DE69501419T2 (de) | 1998-06-25 |
CA2147419A1 (en) | 1995-10-22 |
HUT71603A (en) | 1996-01-29 |
NO951498L (no) | 1995-10-23 |
AU1653595A (en) | 1995-10-19 |
NO951498D0 (no) | 1995-04-20 |
DE69501419D1 (de) | 1998-02-19 |
EP0679393B1 (en) | 1998-01-14 |
JPH07285856A (ja) | 1995-10-31 |
EP0679393A3 (en) | 1995-11-15 |
FI951856A0 (fi) | 1995-04-19 |
ES2116642T3 (es) | 1998-07-16 |
DK0679393T3 (da) | 1998-09-14 |
US5679716A (en) | 1997-10-21 |
HU9501121D0 (en) | 1995-06-28 |
FI951856A (fi) | 1995-10-22 |
KR100350564B1 (ko) | 2002-12-16 |
AU695696B2 (en) | 1998-08-20 |
TW284687B (ko) | 1996-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |