BR9709082A - Processo de esterilização terminal de produtobiologicamente ativo para administração estéril,e, composição - Google Patents

Processo de esterilização terminal de produtobiologicamente ativo para administração estéril,e, composição

Info

Publication number
BR9709082A
BR9709082A BR9709082-4A BR9709082A BR9709082A BR 9709082 A BR9709082 A BR 9709082A BR 9709082 A BR9709082 A BR 9709082A BR 9709082 A BR9709082 A BR 9709082A
Authority
BR
Brazil
Prior art keywords
biologically active
composition
sterilization process
terminal sterilization
products
Prior art date
Application number
BR9709082-4A
Other languages
English (en)
Portuguese (pt)
Inventor
Jaap Kampinga
Robert Alcock
Original Assignee
Quadrant Holdings Cambridge
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadrant Holdings Cambridge filed Critical Quadrant Holdings Cambridge
Publication of BR9709082A publication Critical patent/BR9709082A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR9709082-4A 1996-05-14 1997-05-14 Processo de esterilização terminal de produtobiologicamente ativo para administração estéril,e, composição BR9709082A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/647,515 US6632648B1 (en) 1996-05-14 1996-05-14 Methods of terminal sterilization of fibrinogen
PCT/GB1997/001317 WO1997042980A1 (en) 1996-05-14 1997-05-14 Methods of terminal sterilization of biological products

Publications (1)

Publication Number Publication Date
BR9709082A true BR9709082A (pt) 2001-11-27

Family

ID=24597275

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9709082-4A BR9709082A (pt) 1996-05-14 1997-05-14 Processo de esterilização terminal de produtobiologicamente ativo para administração estéril,e, composição

Country Status (14)

Country Link
US (3) US6632648B1 (enExample)
EP (1) EP0914166B1 (enExample)
JP (1) JP4841018B2 (enExample)
AT (1) ATE245455T1 (enExample)
AU (1) AU730931B2 (enExample)
BR (1) BR9709082A (enExample)
CA (1) CA2254914C (enExample)
DE (1) DE69723703T2 (enExample)
DK (1) DK0914166T3 (enExample)
ES (1) ES2202613T3 (enExample)
NZ (1) NZ333212A (enExample)
PT (1) PT914166E (enExample)
WO (1) WO1997042980A1 (enExample)
ZA (1) ZA974179B (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US6383810B2 (en) 1997-02-14 2002-05-07 Invitrogen Corporation Dry powder cells and cell culture reagents and methods of production thereof
US6627426B2 (en) 1997-02-14 2003-09-30 Invitrogen Corporation Methods for reducing adventitious agents and toxins and cell culture reagents produced thereby
EP1091765A4 (en) * 1998-06-30 2001-10-24 Invitrogen Corp Methods for reducing adventitious agents and toxins and cell culture reagents produced thereby
BR9905867A (pt) * 1998-11-06 2001-01-23 Bio Sidus S A Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula
CA2634663C (en) 1999-02-22 2009-08-25 University Of Connecticut Novel albumin-free factor viii formulations
JP4493769B2 (ja) * 1999-12-21 2010-06-30 旭化成ケミカルズ株式会社 球形顆粒
JP2004526749A (ja) * 2001-04-04 2004-09-02 デルシテク オサケ ユキチュア 生分解性キャリアおよびその製造方法
EP2335650B1 (en) 2003-12-11 2012-10-03 Isto Technologies Inc. Particulate cartilage system
EA010428B1 (ru) 2004-05-27 2008-08-29 Бакстер Интернэшнл Инк. Инактивация патогена в препарате путем обработки формалином и уф светом
CN102091347A (zh) * 2004-10-20 2011-06-15 伊西康公司 可吸收的止血物
HUE031042T2 (en) 2005-07-29 2017-06-28 Abbott Laboratories Gmbh Methods for producing pancreatin powder with low viral content
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
WO2007025290A2 (en) 2005-08-26 2007-03-01 Isto Technologies, Inc. Implants and methods for repair, replacement and treatment of joint disease
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
CN101316602B (zh) 2005-09-27 2015-06-03 组织技术公司 羊膜制品和纯化的组合物及其使用方法
AU2007253380B2 (en) * 2006-05-22 2013-03-14 Abbott Laboratories Gmbh Process for separating and determining the viral load in a pancreatin sample
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
EP2134297B1 (en) 2007-04-12 2017-03-08 Zimmer, Inc. Apparatus for tissue repair
US20120177610A1 (en) * 2007-09-19 2012-07-12 Kieu Hoang Manufacturing and Purification Processes of Complex Protein found in Fraction IV to make a separated Apo, Transferrin , and Alpha 1 Anti strepsin (A1AT) or A combined Transferrin / Apo/Human Albumin/A1AT and all new found proteins
EP2385825B1 (en) 2008-11-07 2018-10-10 University of Connecticut Factor viii formulations
US9827205B2 (en) * 2008-12-12 2017-11-28 Mallinckrodt Pharma Ip Trading D.A.C. Dry powder fibrin sealant
EP2236617A1 (en) 2009-03-31 2010-10-06 Leukocare Ag Methods of terminal sterilization of biofunctional compositions
CN103052407A (zh) * 2010-07-13 2013-04-17 赛福伦公司 苯达莫司汀的改进灭菌方法
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
EP2717888B1 (en) 2011-06-10 2020-09-09 Tissuetech, Inc. Methods of processing fetal support tissues
CN103874762A (zh) 2011-08-26 2014-06-18 组织技术公司 胎儿支持组织的灭菌方法
CA2853112C (en) 2011-10-25 2018-08-21 Onclave Therapeutics Limited Antibody formulations and methods
IN2014MN01939A (enExample) 2012-03-31 2015-07-10 Univ Waseda
ES2846789T3 (es) 2012-07-11 2021-07-29 Tissuetech Inc Composiciones que contienen complejos HC-HA/PTX3 y métodos de uso de los mismos
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
TWI720984B (zh) 2015-05-20 2021-03-11 美商帝聖工業公司 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
IL310285A (en) 2021-08-13 2024-03-01 Biotest Ag Fibrinogen preparations and preparation methods

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557717A (en) 1968-05-17 1971-01-26 Gen Mills Inc Process for making candy floss
US3619294A (en) 1968-07-15 1971-11-09 Penick & Ford Ltd Method of combining crystalline sugar with impregnating agents and products produced thereby
US3632357A (en) 1969-07-29 1972-01-04 Standard Brands Inc Method of producing hard candy
US3655442A (en) 1969-08-27 1972-04-11 California & Hawaiian Sugar Method of making sugar and sugar products
DE2246013A1 (de) 1972-09-20 1974-03-28 Boehringer Mannheim Gmbh Verfahren zur herstellung von poroesen tabletten
US4127502A (en) 1977-06-10 1978-11-28 Eastman Kodak Company Stabilizers for reconstituted, lyophilized samples
LU78955A1 (de) 1978-01-27 1979-09-06 Chimicasa Gmbh Verfahren zur inaktivierung von viren
US4158544A (en) 1978-07-17 1979-06-19 Beckman Instruments, Inc. Process for preparing a biological composition for use as a reference control in diagnostic analysis
US4588744A (en) 1978-09-19 1986-05-13 Mchugh John E Method of forming an aqueous solution of 3-3-Bis(p-hydroxyphenyl)-phthalide
FR2442554A1 (fr) 1978-11-24 1980-06-20 Thomson Brandt Commutateur electronique a commande tactile, et selecteur de canaux comportant un tel commutateur
EP0035204B2 (en) * 1980-03-05 1991-05-22 Miles Inc. Pasteurized therapeutically active protein compositions
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4294826A (en) 1980-05-07 1981-10-13 Armour Pharmaceutical Company Process for the preparation of highly purified antihemophilic factor
US4327076A (en) 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
JPS57140724A (en) 1981-02-25 1982-08-31 Green Cross Corp:The Heat-treatment of aqueous solution containing cold insoluble globulin
US4327077A (en) 1981-05-29 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4879280A (en) 1981-09-24 1989-11-07 Fresenius Ag Dialysis solution for use in intraperitoneal dialysis
US4456590B2 (en) 1981-11-02 1989-05-30 Heat treatment of lyphilized blood clotting factor viii concentrate
US4994438A (en) 1981-11-02 1991-02-19 Cedars Sinai Medical Center Heat treatment of lyophilized plasma fractions
JPS58216695A (ja) 1982-06-07 1983-12-16 Otsuka Shokuhin Kogyo Kk トレハロ−スの製造方法
US4457916A (en) * 1982-08-31 1984-07-03 Asahi Kasei Kogyo Kabushiki Kaisha Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
US4883762A (en) 1983-06-06 1989-11-28 Ciba Corning Diagnostics Corp. Stabilized isoenzyme control products
US4865871A (en) 1983-08-23 1989-09-12 Board Of Regents The University Of Texas System Method for cryopreparing biological tissue
US4490361A (en) 1983-12-02 1984-12-25 Alpha Therapeutic Corporation Virus inactivating heat treatment of plasma fractions
AT389815B (de) 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
JPS60258195A (ja) 1984-06-05 1985-12-20 Ss Pharmaceut Co Ltd α．α―トレハロース脂肪酸ジエステル誘導体
DE3434472A1 (de) 1984-09-20 1986-03-27 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur pasteurisation von plasmaproteinen bzw. von plasmaproteinfraktionen
DE3445010A1 (de) 1984-12-10 1986-06-19 Boehringer Mannheim Gmbh Kontroll- bzw. eichserum fuer die lipid-diagnostik
US4677195A (en) 1985-01-11 1987-06-30 Genetics Institute, Inc. Method for the purification of erythropoietin and erythropoietin compositions
GB8505882D0 (en) 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
GB8508173D0 (en) 1985-03-28 1985-05-01 Standard Telephones Cables Ltd Controlled delivery device
ATE68524T1 (de) 1985-07-09 1991-11-15 Quadrant Bioresources Ltd Beschuetzung von proteinen und aehnlichem.
US4758657A (en) 1985-07-11 1988-07-19 Armour Pharmaceutical Company Method of purifying Factor VIII:C
ATE52922T1 (de) 1985-08-05 1990-06-15 Immuno Ag Verfahren zur herstellung von praeparationen auf basis von blutgerinnungsfaktoren.
CA1276563C (en) 1985-09-30 1990-11-20 Stanley E. Charm High temperature, short time heating system and method of sterilizing heat-sensitive biological fluids
EP0225581A3 (en) * 1985-11-30 1989-05-24 Green Cross Corporation Method for the heat-treatment of immunoglobulins and immunoglobulin product
JPS62228024A (ja) * 1985-11-30 1987-10-06 Green Cross Corp:The 免疫グロブリンの加熱処理方法
JPS62174094A (ja) 1985-12-16 1987-07-30 Ss Pharmaceut Co Ltd α．α―トレハロース誘導体
GB8604983D0 (en) 1986-02-28 1986-04-09 Biocompatibles Ltd Protein preservation
JPH0662436B2 (ja) 1986-05-19 1994-08-17 株式会社ミドリ十字 静注用免疫グロブリン製剤の製造方法
US4762857A (en) 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4749783A (en) 1986-07-11 1988-06-07 Miles Laboratories, Inc. Viral inactivation and purification of active proteins
FR2604157B1 (fr) 1986-09-18 1989-09-01 Air Liquide Structure isotherme
NL8700484A (nl) 1987-02-26 1988-09-16 Victor George Ryhiner Vriesdroogkamer volgens een modulerende directe expansie principe.
US5097018A (en) 1988-05-12 1992-03-17 University Of Southern California Sequential heat treatment of blood-clotting factor products
US5118795A (en) * 1987-05-15 1992-06-02 University Of Southern California Sequential heat treatment of blood-clotting factor products
US5099002A (en) 1987-05-15 1992-03-24 University Of Southern California Sequential improved method for treatment of human blood-clotting factor products
JP2545231B2 (ja) 1987-06-18 1996-10-16 日本ケミカルリサ−チ株式会社 ウロキナ−ゼの加熱による低分子化抑制法
GB8715238D0 (en) 1987-06-29 1987-08-05 Quadrant Bioresources Ltd Food process
US4909940A (en) 1987-12-30 1990-03-20 New York Blood Center, Inc. Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
GB8801338D0 (en) 1988-01-21 1988-02-17 Quadrant Bioresources Ltd Preservation of viruses
US5045446A (en) 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
AU5414990A (en) 1989-04-12 1990-11-05 Aberdeen University Slow release vitreous systems
DK0399321T3 (da) 1989-05-24 1993-08-09 Miles Inc Gelfiltrering af varmebehandlet faktor VIII
GB8917470D0 (en) 1989-07-31 1989-09-13 Quadrant Bioresources Ltd Composition and method
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
IT1246350B (it) 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
AU650678B2 (en) 1990-08-10 1994-06-30 Analytical Control Systems, Inc. Stabilization (using gelatin from a cold water fish) of enzymes in diagnostic controls
US5200399A (en) 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
ES2078052T3 (es) 1991-07-31 1995-12-01 Blatter Farros Ag Aparato rectificador para el rectificado de la superficie cilindrica o esferica de un rodillo en especial de un rodillo de una maquina de manipulacion del papel.
GB9125695D0 (en) 1991-12-03 1992-01-29 Mastavac Limited Medical preparations
DK0615438T3 (da) 1991-12-05 1996-11-11 Mallinckrodt Veterinary Inc En carbohydratglasmatrix til langvarig frigivelse af et terapeutisk middel
US5192743A (en) 1992-01-16 1993-03-09 Genentech, Inc. Reconstitutable lyophilized protein formulation
IT1254359B (it) * 1992-05-11 1995-09-14 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti il-6
JP3182564B2 (ja) 1992-08-24 2001-07-03 味の素ファルマ株式会社 栄養組成物
US5422384A (en) 1992-11-25 1995-06-06 Battelle Memorial Institute Glass/polymer composites and methods of making
JP3168550B2 (ja) 1992-12-02 2001-05-21 株式会社林原生物化学研究所 脱水剤およびそれを用いる含水物の脱水方法並びにその方法で得られる脱水物品
JP3698721B2 (ja) 1993-02-23 2005-09-21 ジェネンテク・インコーポレイテッド 有機溶媒を用いて処理したポリペプチドの賦形剤安定化
WO1995006126A1 (en) 1993-08-24 1995-03-02 Mogen International N.V. Production of trehalose in plants
ATE235919T1 (de) 1994-06-02 2003-04-15 Elan Drug Delivery Ltd Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen
CA2157219C (en) 1994-08-31 2010-10-05 Munehiro Noda Process for purifying recombinant human serum albumin
US5512547A (en) 1994-10-13 1996-04-30 Wisconsin Alumni Research Foundation Pharmaceutical composition of botulinum neurotoxin and method of preparation
JPH08157491A (ja) 1994-11-30 1996-06-18 Hayashibara Biochem Lab Inc トレハロース誘導体の製造方法
GB9501040D0 (en) * 1995-01-19 1995-03-08 Quadrant Holdings Cambridge Dried composition
US6267958B1 (en) * 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
DE19528221C2 (de) * 1995-08-01 1998-10-22 Blutspendedienst Der Drk Lande Verfahren zur Herstellung eines virussicheren, therapeutischen Präparates aus Humanplasma
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen

Also Published As

Publication number Publication date
JP2000511519A (ja) 2000-09-05
EP0914166A1 (en) 1999-05-12
ES2202613T3 (es) 2004-04-01
US20030211592A1 (en) 2003-11-13
PT914166E (pt) 2003-12-31
NZ333212A (en) 2000-05-26
CA2254914A1 (en) 1997-11-20
JP4841018B2 (ja) 2011-12-21
AU730931B2 (en) 2001-03-22
ZA974179B (en) 1997-12-10
AU2784597A (en) 1997-12-05
ATE245455T1 (de) 2003-08-15
WO1997042980A1 (en) 1997-11-20
US20070249033A1 (en) 2007-10-25
DK0914166T3 (da) 2003-11-10
CA2254914C (en) 2008-07-29
US6632648B1 (en) 2003-10-14
EP0914166B1 (en) 2003-07-23
DE69723703D1 (de) 2003-08-28
DE69723703T2 (de) 2004-01-29

Similar Documents

Publication Publication Date Title
PT914166E (pt) Metodos para a esterilidade final de produtos biologicos
ES540919A0 (es) Procedimiento para la inactivacion de germenes patogenos filtrables,capaces de reproducirse,en productos sanguineos
MX7216E (es) Procedimiento mejorado para inactivar los virus presentes en composiciones que contienen enzimas del factor coagulante de la sangre
EP0015055A1 (en) Microwave sterilization of dry protein
CA2034489A1 (en) Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions
BR9908754A (pt) Composições liofilizada e lìquida de polinucleotìdeo e farmacêutica, processos para tratar um paciente mamìfero e para preparar uma composição liofilizada de polinucleotìdeo, produto liofilizado de polinucleotìdeo, e, processo para liofilizar uma composição de polinucleotìdeo
SK190292A3 (en) Virous inactivated blood product and method of its production
NO981868L (no) Preparat og fremgangsmÕte for stabilisering av biologiske materialer ved t°rking uten nedfrysing
US4816251A (en) Method of inactivating reproductive filterable pathogens in fibrinogen and factor XIII compositions
EP0320193A3 (en) Microwave drying and sanitizing of articles
ES2043689T3 (es) Procedimiento para la inactivacion de germenes patogenos filtrables capaces de reproducirse.
AU731581B2 (en) Dry-heat viral inactivation under controlled moisture conditions
AU2002222283A1 (en) Fat replacement material and method of manufacture thereof
ES2327279T3 (es) Procedimiento de inactivacion viral mediante calentamiento en seco.
CN101757616A (zh) 一种安全的冻干哺乳动物源凝血酶制剂及其制备方法
KR940005805A (ko) 단백질 제조에 있어서 바이러스를 불활성화시키는 방법
KR20010007907A (ko) 위생 신발장
Rubinstein et al. Inability of solvent-detergent (SD) treated factor VIII concentrate to inactivate parvoviruses and non-lipid enveloped non-A, non-B hepatitis virus in factor VIII concentrate: advantages to using sterilizing 100 degrees C dry heat treatment
EP0243567B1 (en) Process for preservation of vegetable products
AU663641B2 (en) A blood product, a method of producing the same and a method of determining the virus inactivation capacity of an inactivation treatment
JPH03182261A (ja) 温風発生器
FR2440195A1 (fr) Appareil pour aseptiser rapidement les materiels delicats
UA32749A (uk) Спосіб очистки нарізаних ампул
McIntosh et al. Process Design for the Inactivation of Viruses in the Manufacture of Pharmaceutical Proteins
RU98117264A (ru) Способ инактивации вируса иммунодефицита человека и других вирусов в плазме крови человека с сохранением функциональной активности белков плазмы крови

Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]