BR9707250A - Dihidrobenzofurano e compostos correlatos úteis como agentes antiinflamatórios - Google Patents
Dihidrobenzofurano e compostos correlatos úteis como agentes antiinflamatóriosInfo
- Publication number
- BR9707250A BR9707250A BR9707250A BR9707250A BR9707250A BR 9707250 A BR9707250 A BR 9707250A BR 9707250 A BR9707250 A BR 9707250A BR 9707250 A BR9707250 A BR 9707250A BR 9707250 A BR9707250 A BR 9707250A
- Authority
- BR
- Brazil
- Prior art keywords
- atoms
- dihydrobenzofuran
- branched
- inflammatory agents
- straight
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/595,158 US5684041A (en) | 1996-02-01 | 1996-02-01 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| PCT/US1997/001308 WO1997028143A1 (en) | 1996-02-01 | 1997-01-30 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9707250A true BR9707250A (pt) | 1999-04-06 |
Family
ID=24381988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9707250A BR9707250A (pt) | 1996-02-01 | 1997-01-30 | Dihidrobenzofurano e compostos correlatos úteis como agentes antiinflamatórios |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5684041A (pt) |
| EP (1) | EP0879231B1 (pt) |
| JP (1) | JP3095421B2 (pt) |
| KR (1) | KR100350920B1 (pt) |
| CN (1) | CN1097588C (pt) |
| AT (1) | ATE277031T1 (pt) |
| AU (1) | AU730319B2 (pt) |
| BR (1) | BR9707250A (pt) |
| CA (1) | CA2244194C (pt) |
| DE (1) | DE69730817T2 (pt) |
| DK (1) | DK0879231T3 (pt) |
| ES (1) | ES2229331T3 (pt) |
| MX (1) | MX9806251A (pt) |
| NO (1) | NO983525L (pt) |
| NZ (1) | NZ331618A (pt) |
| WO (1) | WO1997028143A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0516948U (ja) * | 1991-08-16 | 1993-03-02 | 湯浅起市郎 | 金属製板体の吊子構造 |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| CA2531020C (en) * | 2003-06-26 | 2014-03-25 | Takeda Pharmaceutical Company Limited | Cannabinoid receptor modulator |
| GB0322016D0 (en) * | 2003-09-19 | 2003-10-22 | Merck Sharp & Dohme | New compounds |
| US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| WO2006116718A2 (en) | 2005-04-28 | 2006-11-02 | Proteus Biomedical, Inc. | Pharma-informatics system |
| JP2010503710A (ja) | 2006-09-18 | 2010-02-04 | ラプトール ファーマシューティカル インコーポレイテッド | 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置 |
| ES2919563T3 (es) | 2009-02-20 | 2022-07-27 | Enhanx Biopharm Inc | Sistema de administración de medicamentos a base de glutatión |
| EA024559B1 (ru) | 2009-05-06 | 2016-09-30 | Лаборэтори Скин Кэа, Инк. | Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| WO2019182886A1 (en) * | 2018-03-20 | 2019-09-26 | Merck Sharp & Dohme Corp. | Oxo-tetrahydro-isoquinoline carboxylic acids as sting inhibitors |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3252999A (en) * | 1963-11-01 | 1966-05-24 | American Home Prod | Derivatives of 5-amino-2, 3-dihydro-2-methyl benzofuran |
| US3963717A (en) * | 1975-03-10 | 1976-06-15 | Sandoz, Inc. | Tricyclic furo-quinazolinones |
| JPS6019305B2 (ja) * | 1976-07-02 | 1985-05-15 | ウェルファイド株式会社 | ジヒドロベンゾフラン誘導体 |
| CH632268A5 (de) * | 1977-01-14 | 1982-09-30 | Sandoz Ag | Verfahren zur herstellung von neuen heterocyclylaminoderivaten. |
| IT1093805B (it) * | 1978-01-31 | 1985-07-26 | Erba Carlo Spa | Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione |
| US4470440A (en) * | 1982-09-30 | 1984-09-11 | Thor Harry A | Impact producing tool |
| JPS60108846A (ja) * | 1983-11-18 | 1985-06-14 | Konishiroku Photo Ind Co Ltd | ハロゲン化銀写真感光材料 |
| AU556949B2 (en) * | 1984-10-25 | 1986-11-27 | Fmc Corporation | Pyrozoline insecticides |
| US4767779A (en) * | 1985-09-24 | 1988-08-30 | Fmc Corporation | Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them |
| IT206464Z2 (it) * | 1986-02-27 | 1987-08-10 | Alfa Romeo Spa | Impianto di scarico per un motore a c.i.. |
| DE3777366D1 (de) * | 1986-12-27 | 1992-04-16 | Takeda Chemical Industries Ltd | 2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung. |
| US4849428A (en) * | 1987-11-23 | 1989-07-18 | The Procter & Gamble Company | Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use |
| DE3810080A1 (de) * | 1988-03-25 | 1989-10-05 | Bayer Ag | Trisubstituierte 1,3,5-triazin-2,4,6-trione |
| JP2855341B2 (ja) * | 1988-06-10 | 1999-02-10 | 武田薬品工業株式会社 | 新規２―置換クマラン誘導体 |
| US4966907A (en) * | 1988-08-12 | 1990-10-30 | Merck & Co., Inc. | 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis |
| US4975457A (en) * | 1989-09-25 | 1990-12-04 | Merck & Co., Inc. | Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis |
| EP0458970A4 (en) * | 1989-11-17 | 1992-05-13 | Meiji Milk Products Company Limited | Benzofuran derivative, process for preparing the same, and pharmaceutical comprising the same as active ingredient |
| US5091533A (en) * | 1990-03-12 | 1992-02-25 | Merck Frosst Canada, Inc. | 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors |
| AU660277B2 (en) * | 1990-03-27 | 1995-06-22 | Smithkline Beecham Corporation | 5-lipoxygenase inhibitors |
| WO1992012144A1 (fr) * | 1990-12-28 | 1992-07-23 | Teijin Limited | Compose cyclique condense de benzoxa, son procede de production, et composition pharmaceutique le contenant |
| WO1993003011A1 (en) * | 1991-08-08 | 1993-02-18 | Yamanouchi Pharmaceutical Co., Ltd. | Urea derivative |
| FR2682381B1 (fr) * | 1991-10-10 | 1995-04-07 | Rhone Poulenc Rorer Sa | Derives de benzodiazepine, leur preparation et les medicaments les contenant. |
| US5684002A (en) * | 1994-09-07 | 1997-11-04 | The Procter & Gamble Company | Dihydorbenzofuran and related compounds useful as anti-inflammatory agents |
-
1996
- 1996-02-01 US US08/595,158 patent/US5684041A/en not_active Expired - Fee Related
-
1997
- 1997-01-30 BR BR9707250A patent/BR9707250A/pt not_active Application Discontinuation
- 1997-01-30 WO PCT/US1997/001308 patent/WO1997028143A1/en active IP Right Grant
- 1997-01-30 AU AU18428/97A patent/AU730319B2/en not_active Ceased
- 1997-01-30 DE DE69730817T patent/DE69730817T2/de not_active Expired - Fee Related
- 1997-01-30 EP EP97904014A patent/EP0879231B1/en not_active Expired - Lifetime
- 1997-01-30 AT AT97904014T patent/ATE277031T1/de not_active IP Right Cessation
- 1997-01-30 CA CA002244194A patent/CA2244194C/en not_active Expired - Fee Related
- 1997-01-30 NZ NZ331618A patent/NZ331618A/xx unknown
- 1997-01-30 DK DK97904014T patent/DK0879231T3/da active
- 1997-01-30 ES ES97904014T patent/ES2229331T3/es not_active Expired - Lifetime
- 1997-01-30 KR KR1019980705951A patent/KR100350920B1/ko not_active IP Right Cessation
- 1997-01-30 CN CN97191977A patent/CN1097588C/zh not_active Expired - Fee Related
- 1997-01-30 JP JP09527757A patent/JP3095421B2/ja not_active Expired - Fee Related
-
1998
- 1998-07-31 NO NO983525A patent/NO983525L/no not_active Application Discontinuation
- 1998-08-03 MX MX9806251A patent/MX9806251A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11503467A (ja) | 1999-03-26 |
| NZ331618A (en) | 2000-08-25 |
| EP0879231B1 (en) | 2004-09-22 |
| MX9806251A (es) | 1998-11-30 |
| DE69730817D1 (de) | 2004-10-28 |
| DE69730817T2 (de) | 2005-02-03 |
| ES2229331T3 (es) | 2005-04-16 |
| JP3095421B2 (ja) | 2000-10-03 |
| KR100350920B1 (ko) | 2002-11-18 |
| DK0879231T3 (da) | 2004-12-20 |
| CA2244194A1 (en) | 1997-08-07 |
| CN1210529A (zh) | 1999-03-10 |
| NO983525L (no) | 1998-09-30 |
| EP0879231A1 (en) | 1998-11-25 |
| CA2244194C (en) | 2003-05-06 |
| ATE277031T1 (de) | 2004-10-15 |
| US5684041A (en) | 1997-11-04 |
| WO1997028143A1 (en) | 1997-08-07 |
| AU1842897A (en) | 1997-08-22 |
| KR19990082223A (ko) | 1999-11-25 |
| CN1097588C (zh) | 2003-01-01 |
| NO983525D0 (no) | 1998-07-31 |
| AU730319B2 (en) | 2001-03-01 |
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| BR9707321A (pt) | Dihidrobenzofurano e compostor correlatos úteis como agentes antinflamatórios | |
| ES2196301T3 (es) | Dihidrobenzofurano y compuestos relacionados utilizados como agentes anti-inflamatorios. | |
| MX9806247A (es) | Dihidrobenzofurano y compuestos relacionados utiles como agentes antiinflamatorios. | |
| CA2244245A1 (en) | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: VANDERBILT UNIVERSITY (US) |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 36O DA LPI |