DK0879231T3 - Dihydrobenzofuran og beslægtede forbindelser, der er nyttige som antiinflammatoriske midler - Google Patents
Dihydrobenzofuran og beslægtede forbindelser, der er nyttige som antiinflammatoriske midlerInfo
- Publication number
- DK0879231T3 DK0879231T3 DK97904014T DK97904014T DK0879231T3 DK 0879231 T3 DK0879231 T3 DK 0879231T3 DK 97904014 T DK97904014 T DK 97904014T DK 97904014 T DK97904014 T DK 97904014T DK 0879231 T3 DK0879231 T3 DK 0879231T3
- Authority
- DK
- Denmark
- Prior art keywords
- atoms
- dihydrobenzofuran
- branched
- inflammatory agents
- straight
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/595,158 US5684041A (en) | 1996-02-01 | 1996-02-01 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
EP97904014A EP0879231B1 (en) | 1996-02-01 | 1997-01-30 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0879231T3 true DK0879231T3 (da) | 2004-12-20 |
Family
ID=24381988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97904014T DK0879231T3 (da) | 1996-02-01 | 1997-01-30 | Dihydrobenzofuran og beslægtede forbindelser, der er nyttige som antiinflammatoriske midler |
Country Status (16)
Country | Link |
---|---|
US (1) | US5684041A (da) |
EP (1) | EP0879231B1 (da) |
JP (1) | JP3095421B2 (da) |
KR (1) | KR100350920B1 (da) |
CN (1) | CN1097588C (da) |
AT (1) | ATE277031T1 (da) |
AU (1) | AU730319B2 (da) |
BR (1) | BR9707250A (da) |
CA (1) | CA2244194C (da) |
DE (1) | DE69730817T2 (da) |
DK (1) | DK0879231T3 (da) |
ES (1) | ES2229331T3 (da) |
MX (1) | MX9806251A (da) |
NO (1) | NO983525L (da) |
NZ (1) | NZ331618A (da) |
WO (1) | WO1997028143A1 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0516948U (ja) * | 1991-08-16 | 1993-03-02 | 湯浅起市郎 | 金属製板体の吊子構造 |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
SI1637527T1 (sl) | 2003-06-26 | 2013-07-31 | Takeda Pharmaceutical Company Limited | Modulator kanabinoidnega receptorja |
GB0322016D0 (en) * | 2003-09-19 | 2003-10-22 | Merck Sharp & Dohme | New compounds |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
CA2969926C (en) | 2009-02-20 | 2018-05-15 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
EP3768266A4 (en) * | 2018-03-20 | 2021-12-22 | Merck Sharp & Dohme Corp. | OXO-TETRAHYDRO-ISOQUINOLINE CARBOXYLIC ACIDS AS STING PROTEIN INHIBITORS |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3252999A (en) * | 1963-11-01 | 1966-05-24 | American Home Prod | Derivatives of 5-amino-2, 3-dihydro-2-methyl benzofuran |
US3963717A (en) * | 1975-03-10 | 1976-06-15 | Sandoz, Inc. | Tricyclic furo-quinazolinones |
JPS6019305B2 (ja) * | 1976-07-02 | 1985-05-15 | ウェルファイド株式会社 | ジヒドロベンゾフラン誘導体 |
CH632268A5 (de) * | 1977-01-14 | 1982-09-30 | Sandoz Ag | Verfahren zur herstellung von neuen heterocyclylaminoderivaten. |
IT1093805B (it) * | 1978-01-31 | 1985-07-26 | Erba Carlo Spa | Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione |
US4470440A (en) * | 1982-09-30 | 1984-09-11 | Thor Harry A | Impact producing tool |
JPS60108846A (ja) * | 1983-11-18 | 1985-06-14 | Konishiroku Photo Ind Co Ltd | ハロゲン化銀写真感光材料 |
AU556949B2 (en) * | 1984-10-25 | 1986-11-27 | Fmc Corporation | Pyrozoline insecticides |
US4767779A (en) * | 1985-09-24 | 1988-08-30 | Fmc Corporation | Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them |
IT206464Z2 (it) * | 1986-02-27 | 1987-08-10 | Alfa Romeo Spa | Impianto di scarico per un motore a c.i.. |
DE3777366D1 (de) * | 1986-12-27 | 1992-04-16 | Takeda Chemical Industries Ltd | 2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung. |
US4849428A (en) * | 1987-11-23 | 1989-07-18 | The Procter & Gamble Company | Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use |
DE3810080A1 (de) * | 1988-03-25 | 1989-10-05 | Bayer Ag | Trisubstituierte 1,3,5-triazin-2,4,6-trione |
JP2855341B2 (ja) * | 1988-06-10 | 1999-02-10 | 武田薬品工業株式会社 | 新規2―置換クマラン誘導体 |
US4966907A (en) * | 1988-08-12 | 1990-10-30 | Merck & Co., Inc. | 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis |
US4975457A (en) * | 1989-09-25 | 1990-12-04 | Merck & Co., Inc. | Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis |
WO1991007396A1 (en) * | 1989-11-17 | 1991-05-30 | Meiji Milk Products Co., Ltd. | Benzofuran derivative, process for preparing the same, and pharmaceutical comprising the same as active ingredient |
US5091533A (en) * | 1990-03-12 | 1992-02-25 | Merck Frosst Canada, Inc. | 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors |
CA2078126A1 (en) * | 1990-03-27 | 1991-09-28 | Jerry Leroy Adams | 5-lipoxygenase inhibitors |
ES2145743T3 (es) * | 1990-12-28 | 2000-07-16 | Teijin Ltd | Compuesto de anillo condensado benzoxa, su produccion y composicion farmaceutica que lo contiene. |
WO1993003011A1 (en) * | 1991-08-08 | 1993-02-18 | Yamanouchi Pharmaceutical Co., Ltd. | Urea derivative |
FR2682381B1 (fr) * | 1991-10-10 | 1995-04-07 | Rhone Poulenc Rorer Sa | Derives de benzodiazepine, leur preparation et les medicaments les contenant. |
US5684002A (en) * | 1994-09-07 | 1997-11-04 | The Procter & Gamble Company | Dihydorbenzofuran and related compounds useful as anti-inflammatory agents |
-
1996
- 1996-02-01 US US08/595,158 patent/US5684041A/en not_active Expired - Fee Related
-
1997
- 1997-01-30 DE DE69730817T patent/DE69730817T2/de not_active Expired - Fee Related
- 1997-01-30 JP JP09527757A patent/JP3095421B2/ja not_active Expired - Fee Related
- 1997-01-30 BR BR9707250A patent/BR9707250A/pt not_active Application Discontinuation
- 1997-01-30 DK DK97904014T patent/DK0879231T3/da active
- 1997-01-30 KR KR1019980705951A patent/KR100350920B1/ko not_active IP Right Cessation
- 1997-01-30 AT AT97904014T patent/ATE277031T1/de not_active IP Right Cessation
- 1997-01-30 EP EP97904014A patent/EP0879231B1/en not_active Expired - Lifetime
- 1997-01-30 ES ES97904014T patent/ES2229331T3/es not_active Expired - Lifetime
- 1997-01-30 CN CN97191977A patent/CN1097588C/zh not_active Expired - Fee Related
- 1997-01-30 NZ NZ331618A patent/NZ331618A/xx unknown
- 1997-01-30 AU AU18428/97A patent/AU730319B2/en not_active Ceased
- 1997-01-30 WO PCT/US1997/001308 patent/WO1997028143A1/en active IP Right Grant
- 1997-01-30 CA CA002244194A patent/CA2244194C/en not_active Expired - Fee Related
-
1998
- 1998-07-31 NO NO983525A patent/NO983525L/no not_active Application Discontinuation
- 1998-08-03 MX MX9806251A patent/MX9806251A/es not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE277031T1 (de) | 2004-10-15 |
DE69730817T2 (de) | 2005-02-03 |
NO983525L (no) | 1998-09-30 |
DE69730817D1 (de) | 2004-10-28 |
US5684041A (en) | 1997-11-04 |
JP3095421B2 (ja) | 2000-10-03 |
EP0879231B1 (en) | 2004-09-22 |
JPH11503467A (ja) | 1999-03-26 |
CA2244194C (en) | 2003-05-06 |
CN1097588C (zh) | 2003-01-01 |
EP0879231A1 (en) | 1998-11-25 |
MX9806251A (es) | 1998-11-30 |
NO983525D0 (no) | 1998-07-31 |
CN1210529A (zh) | 1999-03-10 |
KR19990082223A (ko) | 1999-11-25 |
CA2244194A1 (en) | 1997-08-07 |
WO1997028143A1 (en) | 1997-08-07 |
NZ331618A (en) | 2000-08-25 |
ES2229331T3 (es) | 2005-04-16 |
AU730319B2 (en) | 2001-03-01 |
BR9707250A (pt) | 1999-04-06 |
KR100350920B1 (ko) | 2002-11-18 |
AU1842897A (en) | 1997-08-22 |
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