BR9508031A - Composto antiviral composição farmacéutica ou veterinária e processo para o tratamento antiviral profilático ou terapéuitco de um humano ou animal náo humano e uso do composto - Google Patents

Composto antiviral composição farmacéutica ou veterinária e processo para o tratamento antiviral profilático ou terapéuitco de um humano ou animal náo humano e uso do composto

Info

Publication number
BR9508031A
BR9508031A BR9508031A BR9508031A BR9508031A BR 9508031 A BR9508031 A BR 9508031A BR 9508031 A BR9508031 A BR 9508031A BR 9508031 A BR9508031 A BR 9508031A BR 9508031 A BR9508031 A BR 9508031A
Authority
BR
Brazil
Prior art keywords
compound
human
antiviral
prophylactic
veterinary composition
Prior art date
Application number
BR9508031A
Other languages
English (en)
Inventor
Barry Ross Mattews
George Holan
Original Assignee
Biomolecular Res Inst Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomolecular Res Inst Ltd filed Critical Biomolecular Res Inst Ltd
Publication of BR9508031A publication Critical patent/BR9508031A/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595Polyamides, e.g. nylon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10Alpha-amino-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48Polymers modified by chemical after-treatment
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/16Dendrimers and dendritic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pulmonology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR9508031A 1994-06-15 1995-06-15 Composto antiviral composição farmacéutica ou veterinária e processo para o tratamento antiviral profilático ou terapéuitco de um humano ou animal náo humano e uso do composto BR9508031A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPM6239A AUPM623994A0 (en) 1994-06-15 1994-06-15 Antiviral dendrimers
PCT/AU1995/000350 WO1995034595A1 (en) 1994-06-15 1995-06-15 Antiviral dendrimers

Publications (1)

Publication Number Publication Date
BR9508031A true BR9508031A (pt) 1997-09-16

Family

ID=3780809

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9508031A BR9508031A (pt) 1994-06-15 1995-06-15 Composto antiviral composição farmacéutica ou veterinária e processo para o tratamento antiviral profilático ou terapéuitco de um humano ou animal náo humano e uso do composto

Country Status (16)

Country Link
US (1) US6190650B1 (pt)
EP (1) EP0765357B9 (pt)
JP (2) JPH10501568A (pt)
KR (1) KR100365028B1 (pt)
CN (1) CN1134486C (pt)
AT (1) ATE312866T1 (pt)
AU (1) AUPM623994A0 (pt)
BR (1) BR9508031A (pt)
CA (1) CA2192446C (pt)
DE (1) DE69534686T2 (pt)
DK (1) DK0765357T3 (pt)
ES (1) ES2255060T3 (pt)
HK (1) HK1002899A1 (pt)
NZ (1) NZ287819A (pt)
PT (1) PT765357E (pt)
WO (1) WO1995034595A1 (pt)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2324534B (en) * 1996-01-06 2000-05-10 Danbiosyst Uk Composition for delivery of nucleic acid to a cell
US5795582A (en) * 1996-02-07 1998-08-18 Novavax, Inc. Adjuvant properties of poly (amidoamine) dendrimers
AUPO104496A0 (en) 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Angiogenic inhibitory compounds
AUPO104396A0 (en) 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Antiviral linear polymers
AU3880097A (en) 1996-08-14 1998-03-06 Warner-Lambert Company Low molecular weight dendritic compounds as pharmaceutical agents
DE19726340C2 (de) * 1996-08-16 1999-05-06 Schering Ag Zinndendrimere, ihre Verwendung als Röntgenkontrastmittel und Verfahren zu ihrer Herstellung
US6720355B2 (en) * 1997-02-21 2004-04-13 The Regents Of The University Of California Sodium dodecyl sulfate compositions for inactivating prions
US6331296B1 (en) * 1999-06-01 2001-12-18 Stanley B. Prusiner Food additives which affect conformationally altered proteins
US6719988B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
US20060008494A1 (en) * 1997-02-21 2006-01-12 The Regents Of The University Of California Complete inactivation of infectious proteins
FR2761691B1 (fr) * 1997-04-03 1999-05-14 Oreal Polymeres a fonction terminale thiol
FR2772770B1 (fr) * 1997-12-19 2000-01-28 Oreal Nouveaux composes choisis parmi les polymeres hyperbranches et les dendrimeres ayant un groupement particulier, procede de preparation, utilisation et compositions les comprenant
FR2772771B1 (fr) * 1997-12-19 2000-01-28 Oreal Utilisation de polymeres hyperbranches et de dendrimeres comportant un groupement particulier, en tant qu'agent filmogene, les compositions filmogenes les comprenant et leur utilisation notamment en cosmetique ou en pharmacie
FR2781485B1 (fr) 1998-07-21 2003-08-08 Denis Barritault Polymeres biocompatibles leur procede de preparation et les compositions les contenant
EP1609467A1 (en) * 1998-07-28 2005-12-28 Neurochem (International) Limited Compositions for treating diseases associated with glycosaminoglycan-associated molecular interactions
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
US7572459B2 (en) * 1998-09-14 2009-08-11 Starpharma Pty Ltd. Anionic or cationic dendrimer antimicrobial or antiparasitic compositions
AU767971B2 (en) * 1998-09-14 2003-11-27 Starpharma Pty Limited Inhibition of toxic materials or substances using dendrimers
AU767970B2 (en) * 1998-09-14 2003-11-27 Starpharma Pty Limited Anionic or cationic dendrimer antimicrobial or antiparasitic compositions
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
SE9904289D0 (sv) * 1999-11-26 1999-11-26 Niklas Arnberg Method and camposition for the treatment of adenovairal ocular infections
AUPR001000A0 (en) * 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
DE10065710A1 (de) * 2000-12-29 2002-07-04 Bayer Ag Arzneimittel enthaltend ein Polyamin als Wirksubstanz
AUPR412801A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agent for the prevention and treatment of sexually transmitted disease s - I
AUPR412901A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agents for the prevention and treatment of sexually transmitted disease s - II
US20030180250A1 (en) * 2002-03-22 2003-09-25 Council Of Scientific And Industrial Research Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents
AU2002249486A1 (en) * 2002-03-26 2003-10-08 Council Of Scientific And Industrial Research Macromolecular compounds as potential anti-inflammatory agents
GB0209022D0 (en) 2002-04-19 2002-05-29 Imp College Innovations Ltd Compounds
WO2004009666A2 (en) * 2002-07-19 2004-01-29 The Regents Of The University Of California Dendrimers as molecular translocators
US7001580B2 (en) * 2002-12-31 2006-02-21 3M Innovative Properties Company Emulsions including surface-modified organic molecules
GR1004516B (el) * 2003-02-13 2004-04-06 Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) - "Δημοκριτος" Πολυ-λειτουργικα δενδριμερικα και υπερδιακλαδισμενα πολυμερη ως φορεις φαρμακων
WO2004072153A1 (en) * 2003-02-13 2004-08-26 National Center For Scientific Research 'demokritos' Multifunctional dendrimers and hyperbranched polymers as drug and gene delivery systems
US20040180852A1 (en) * 2003-03-10 2004-09-16 Cara-Lynne Schengrund Use of multivalent glycodendrimers to inhibit the activity of human immunodeficiency virus
BRPI0510093B8 (pt) 2004-04-20 2022-12-27 Dendritic Nanotechnologies Inc polímeros dendríticos
US7985424B2 (en) 2004-04-20 2011-07-26 Dendritic Nanotechnologies Inc. Dendritic polymers with enhanced amplification and interior functionality
EP1817325B1 (en) * 2004-09-21 2009-01-21 Lehigh University Sulfated molecular umbrellas containing 6-200 cholanic acid (derivative) units as anti-hiv and anti-hsv agents
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US8790672B2 (en) * 2005-02-22 2014-07-29 Nina M. Lamba-Kohli Generation of antimicrobial surfaces using dendrimer biocides
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
HUE026628T2 (en) 2005-09-15 2016-06-28 Genzyme Corp Pouches for amine polymers
RU2396962C2 (ru) * 2005-10-18 2010-08-20 Старфарма Пти Лимитед Система доставки микробицидных дендримерных композиций
WO2007045010A1 (en) * 2005-10-21 2007-04-26 Starpharma Pty Limited Inhibitory compounds
DE102005056592A1 (de) * 2005-11-25 2007-05-31 Basf Ag Herstellung und Verwendung von hochfunktionellen, hoch-oder hyperverzweigten Polylysinen
CA2647325C (en) * 2005-12-12 2015-03-24 Allaccem, Inc. Methods and systems for preparing antimicrobial bridged polycyclic compounds
CN101003607B (zh) * 2006-01-16 2010-09-01 博阳生物科技(上海)有限公司 封闭树状大分子的方法、经封闭的树状大分子及其用途
CA2636599C (en) * 2006-01-20 2014-07-15 Starpharma Pty Limited Modified macromolecule
CN101405010B (zh) 2006-03-22 2013-03-06 星药股份有限公司 避孕组合物
EP2016114A2 (en) * 2006-05-05 2009-01-21 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
BRPI0715053A2 (pt) * 2006-07-18 2013-03-19 Genzyme Corp composiÇço farmacÊutica, mÉtodo para tratar doenÇas, e, polÍmero
US8425887B2 (en) 2006-09-29 2013-04-23 Genzyme Corporation Amide dendrimer compositions
US20100028402A1 (en) * 2006-10-25 2010-02-04 Marina Dobrovolskaia Nanoparticle-based anticoagulant
US8163799B2 (en) * 2006-12-14 2012-04-24 Genzyme Corporation Amido-amine polymer compositions
NZ579785A (en) 2007-02-21 2012-06-29 Allaccem Inc Bridged polycyclic compound based compositions for the inhibition and amelioration of disease
WO2008103368A1 (en) * 2007-02-23 2008-08-28 Genzyme Corporation Amine polymer compositions
US20100196305A1 (en) * 2007-03-08 2010-08-05 Dhal Pradeep K Sulfone polymer compositions
EP2152277A1 (en) * 2007-04-27 2010-02-17 Genzyme Corporation Amido-amine dendrimer compositions
WO2008157372A2 (en) 2007-06-14 2008-12-24 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
WO2009078958A1 (en) * 2007-12-14 2009-06-25 Genzyme Corporation Coated pharmaceutical compositions
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
US20110142952A1 (en) * 2008-06-20 2011-06-16 Harris David J Pharmaceutical Compositions
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
US9198875B2 (en) 2008-08-17 2015-12-01 Massachusetts Institute Of Technology Controlled delivery of bioactive agents from decomposable films
WO2011036560A2 (en) 2009-09-23 2011-03-31 Novartis Ag Glycoconjugate compositions and methods for treatment of hiv
KR20180126621A (ko) * 2011-05-16 2018-11-27 스타파마 피티와이 리미티드 세균성 질염의 치료 또는 예방 방법
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
EP2586461A1 (en) 2011-10-27 2013-05-01 Christopher L. Parks Viral particles derived from an enveloped virus
US9347065B2 (en) 2012-03-29 2016-05-24 International Aids Vaccine Initiative Methods to improve vector expression and genetic stability
US10278927B2 (en) 2012-04-23 2019-05-07 Massachusetts Institute Of Technology Stable layer-by-layer coated particles
CN108452316B (zh) * 2012-09-13 2022-04-15 星法马有限公司 眼部感染的治疗或预防方法
WO2014134029A1 (en) 2013-02-26 2014-09-04 Massachusetts Institute Of Technology Nucleic acid particles, methods and use thereof
US9463244B2 (en) 2013-03-15 2016-10-11 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
EP2987503A1 (en) * 2014-08-22 2016-02-24 Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Methods and reagents for prevention and/or treatment of infection
US12071516B2 (en) 2014-09-04 2024-08-27 Nano Precision Medical, Inc. Polymeric stabilizing formulations
US10479868B2 (en) 2014-09-04 2019-11-19 Nano Precision Medical, Inc. Polymeric stabilizing formulations
US10154956B2 (en) * 2015-07-28 2018-12-18 Carnegie Mellon University Methods and compounds to suppress viral genome release and packaging
US10702572B2 (en) 2015-07-28 2020-07-07 Carnegie Mellon University Methods and compounds to suppress viral genome release and packaging
US20210030785A1 (en) * 2016-05-05 2021-02-04 Starpharma Pty Ltd. Method of prophylaxis of zika virus infection
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2021002984A1 (en) 2019-05-30 2021-01-07 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
GB2601680B (en) * 2019-08-05 2023-02-22 Ibm Polylysine polymers with antimicrobial and/or anticancer activity
WO2021207790A1 (en) * 2020-04-15 2021-10-21 Starpharma Pty Ltd Method of prophylaxis of coronavirus and/or respiratory syncytial virus infection
GB202007701D0 (en) 2020-05-22 2020-07-08 Univ Manchester Antiviral polymers
CN114053392B (zh) * 2020-07-30 2024-06-21 广州朗圣药业有限公司 新型化合物在制备预防和/或治疗hpv感染的药物中的应用
CN114053394B (zh) * 2020-07-30 2024-06-21 广州朗圣药业有限公司 新型化合物在制备预防和/或治疗冠状病毒感染的药物中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410688A (en) * 1981-04-29 1983-10-18 Allied Corporation Macromolecular highly branched homogeneous compound
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4599400A (en) 1984-12-18 1986-07-08 The Dow Chemical Company Star/comb-branched polyamide
ATE89743T1 (de) 1986-08-18 1993-06-15 Dow Chemical Co Conjugate dichter sterne.
US5229490A (en) * 1987-05-06 1993-07-20 The Rockefeller University Multiple antigen peptide system
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
EP0339695A3 (en) * 1988-04-29 1990-05-30 Stichting Voor De Technische Wetenschappen A process for preparing an antigenic or immunogenic conjugate as well as the use of such conjugates
JPH03236366A (ja) * 1989-12-22 1991-10-22 Banyu Pharmaceut Co Ltd グアニジノベンゼン誘導体
US5312837A (en) * 1991-01-29 1994-05-17 Genelabs Technologies, Inc. Method of treating viral infections with aryl macrocyclic compounds
NL9100434A (nl) * 1991-03-11 1992-10-01 Rijksuniversiteit Farmaceutische preparaten voor de bestrijding van virale infecties en immuundeficientieziekten, de bereiding en toepassing daarvan.
WO1993003766A1 (en) 1991-08-13 1993-03-04 Repligen Corporation Multiple antigen peptides for use as hiv vaccines
WO1993009132A1 (en) * 1991-11-01 1993-05-13 Smithkline Beecham Corporation Hiv protease inhibitors containing guanidine
DE69433519T2 (de) 1993-07-14 2004-11-11 The Regents Of The University Of California, Oakland Sich selbst zusammensetzendes polynukleotid-abgabesystem, das dendrimer-polykationen enthält

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CN1134486C (zh) 2004-01-14
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CN1154123A (zh) 1997-07-09
HK1002899A1 (en) 1998-09-25
ES2255060T3 (es) 2006-06-16
JP4589851B2 (ja) 2010-12-01
PT765357E (pt) 2006-05-31
EP0765357A1 (en) 1997-04-02
US6190650B1 (en) 2001-02-20
EP0765357B1 (en) 2005-12-14
ATE312866T1 (de) 2005-12-15
WO1995034595A1 (en) 1995-12-21
AUPM623994A0 (en) 1994-07-07
CA2192446A1 (en) 1995-12-21
DK0765357T3 (da) 2006-07-17
DE69534686T2 (de) 2006-09-21
CA2192446C (en) 2004-08-31
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KR100365028B1 (ko) 2003-05-12

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