BR9304453A - Vacina e processo para sua produçao, amostra biologicamente pura de um vírus ou agente infeccioso, composiçao e processo para proteger um porco contra infecçao viral, anticorpo, processo para tratar um porco sofrendo de uma doença respiratório e de reproduçao dos suínos, kit diagnóstico, polinucleotídio, proteína, ácido polinucleico isolado e processo para cultivar um vírus - Google Patents
Vacina e processo para sua produçao, amostra biologicamente pura de um vírus ou agente infeccioso, composiçao e processo para proteger um porco contra infecçao viral, anticorpo, processo para tratar um porco sofrendo de uma doença respiratório e de reproduçao dos suínos, kit diagnóstico, polinucleotídio, proteína, ácido polinucleico isolado e processo para cultivar um vírusInfo
- Publication number
- BR9304453A BR9304453A BR9304453A BR9304453A BR9304453A BR 9304453 A BR9304453 A BR 9304453A BR 9304453 A BR9304453 A BR 9304453A BR 9304453 A BR9304453 A BR 9304453A BR 9304453 A BR9304453 A BR 9304453A
- Authority
- BR
- Brazil
- Prior art keywords
- virus
- pig
- pigs
- vaccine
- polynucleotide
- Prior art date
Links
- 238000000034 method Methods 0.000 title 4
- 241000700605 Viruses Species 0.000 title 2
- 102000040430 polynucleotide Human genes 0.000 title 2
- 108091033319 polynucleotide Proteins 0.000 title 2
- 238000009007 Diagnostic Kit Methods 0.000 title 1
- 241000282887 Suidae Species 0.000 title 1
- 208000036142 Viral infection Diseases 0.000 title 1
- 239000012678 infectious agent Substances 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 208000017443 reproductive system disease Diseases 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 208000023504 respiratory system disease Diseases 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/815—Viral vaccine for porcine species, e.g. swine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96907192A | 1992-10-30 | 1992-10-30 | |
US08/131,625 US5695766A (en) | 1992-10-30 | 1993-10-05 | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9304453A true BR9304453A (pt) | 1994-06-14 |
Family
ID=26829656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9304453A BR9304453A (pt) | 1992-10-30 | 1993-11-01 | Vacina e processo para sua produçao, amostra biologicamente pura de um vírus ou agente infeccioso, composiçao e processo para proteger um porco contra infecçao viral, anticorpo, processo para tratar um porco sofrendo de uma doença respiratório e de reproduçao dos suínos, kit diagnóstico, polinucleotídio, proteína, ácido polinucleico isolado e processo para cultivar um vírus |
Country Status (12)
Country | Link |
---|---|
US (4) | US5695766A (pt) |
EP (1) | EP0595436B1 (pt) |
JP (1) | JP4125385B2 (pt) |
CN (1) | CN1087175C (pt) |
AU (1) | AU672825B2 (pt) |
BR (1) | BR9304453A (pt) |
CA (1) | CA2102036C (pt) |
DE (1) | DE69334141T2 (pt) |
DK (1) | DK0595436T3 (pt) |
ES (1) | ES2286815T3 (pt) |
MX (1) | MXPA93006804A (pt) |
TW (2) | TW517085B (pt) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2103460C (en) | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
US6042830A (en) * | 1992-08-05 | 2000-03-28 | Boehringer Ingelheim Vetmedica, Inc. | Viral agent associated with mystery swine disease |
US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
US6773908B1 (en) | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
US6592873B1 (en) | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
US6251397B1 (en) | 1992-10-30 | 2001-06-26 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same |
CZ289743B6 (cs) * | 1993-02-08 | 2002-03-13 | Bayer Corporation | Izolát viru vepřového reprodukčního a respiračního syndromu PRRSV, způsob kultivace PRRSV, tkáňová kultura, způsob přípravy vakcíny a vakcína obsahující PRRSV izolát |
CA2158651C (en) * | 1993-03-29 | 2009-09-01 | David S. Roberts | Multicomponent clostridial vaccines using saponin adjuvants |
GB2289279B (en) * | 1994-05-13 | 1998-09-16 | Iberica Cyanamid | Diagnostic kits and vaccines containing recombinant PRRSV proteins |
ES2078187B1 (es) * | 1994-05-13 | 1996-07-16 | Cynamid Iberica S A | Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes. |
DE69535061T2 (de) * | 1994-08-05 | 2007-01-25 | Regents Of The University Of Minnesota, Minneapolis | Virale nukleotidsequenz vr-2332 und nutzungsverfahren |
US5690940A (en) * | 1995-06-21 | 1997-11-25 | Regents Of The University Of Minnesota | Low pathogencity PRRS live virus vaccines and methods of preparation thereof |
DE69636112T2 (de) * | 1995-08-30 | 2006-12-14 | Toray Industries, Inc. | Verfahren zum testen von myocarditis und cardiomyopathie |
JP3135069B2 (ja) * | 1996-03-01 | 2001-02-13 | シェーリング コーポレイション | ブタ生殖および呼吸症候群ワクチン |
US5866401A (en) * | 1996-03-01 | 1999-02-02 | Schering Corporation | Porcine reproductive and respiratory syndrome vaccine |
US6015663A (en) * | 1996-03-01 | 2000-01-18 | The United States Of America As Represented By The Secretary Of Agriculture | Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains |
PT835930E (pt) * | 1996-10-09 | 2001-06-29 | Akzo Nobel Nv | Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv) |
US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
DE69837992T2 (de) | 1997-05-06 | 2008-03-20 | Boehringer Ingelheim Vetmedica Gmbh | Prrsv-antigene, die auf peptidsequenzen des prrs-virus basieren, für die verwendung als impfstoff und für diagnostische tests |
ZA991641B (en) * | 1998-03-02 | 2000-09-01 | Lilly Co Eli | Treatment of viral disease in swine. |
NZ501264A (en) | 1998-12-22 | 2001-09-28 | Pfizer Prod Inc | Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS |
EP1157121B1 (en) * | 1999-03-08 | 2013-04-24 | Boehringer Ingelheim Vetmedica GmbH | Prrsv replicon |
MXPA01010681A (es) | 1999-04-22 | 2003-08-20 | Us Agriculture | Vacuna de sindrome respiratorio y reproductiva porcina a base de ja-142 aislado. |
GB9930359D0 (en) * | 1999-12-22 | 2000-02-09 | Glaxo Group Ltd | Novel polypeptides |
DK1255815T3 (da) * | 2000-02-08 | 2006-10-30 | Univ Minnesota | Porcint reproduktivt og respiratorisk syndromvirus til fremgangsmåder til anvendelse |
AU2002249852A1 (en) * | 2000-11-09 | 2002-08-12 | Board Of Trustees Of The University Of Illinois | Enhancement of immune response to vaccine by interferon alpha |
US6740490B2 (en) * | 2001-01-29 | 2004-05-25 | Kansas State University Research Foundation | Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding |
EP1357943A2 (en) * | 2001-01-30 | 2003-11-05 | The Lauridsen Group Incorporated | Methods and compositions for modulating the immune system of animals |
EP1397498A1 (en) * | 2001-05-21 | 2004-03-17 | ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. | Delections in arterivirus replicons |
US7479482B2 (en) * | 2001-11-21 | 2009-01-20 | New York University | Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid β, prion protein, amylin, α-synuclein, or polyglutamine repeats for induction of an immune response thereto |
US6841364B2 (en) | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
US20040197845A1 (en) * | 2002-08-30 | 2004-10-07 | Arjang Hassibi | Methods and apparatus for pathogen detection, identification and/or quantification |
WO2004110370A2 (en) * | 2003-06-03 | 2004-12-23 | Iowa State University Research Foundation, Inc. | Etiologic agnet for sow infertility syndrome |
AR049924A1 (es) * | 2004-06-18 | 2006-09-13 | Univ Minnesota | Identificacion de organismos viralmente infectados y vacunados |
US7632636B2 (en) * | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
CA2894069C (en) | 2005-06-24 | 2019-02-26 | Regents Of The University Of Minnesota | Prrs viruses, infectious clones, mutants thereof, and methods of use |
CN106075422B (zh) * | 2005-11-29 | 2021-05-28 | 衣阿华州立大学研究基金公司 | 猪繁殖与呼吸综合征病毒(prrsv)的保护性抗原决定子的鉴定及其用途 |
AR064888A1 (es) * | 2007-01-12 | 2009-04-29 | Univ Illinois | Celulas no simias para el crecimiento del virus del sindrome reproductor y respiratorio porcino (prrs) |
AU2008294036A1 (en) * | 2007-05-30 | 2009-03-05 | Wyeth Llc | Raccoon poxvirus expressing genes of porcine virus |
US7666585B2 (en) * | 2007-06-15 | 2010-02-23 | Protatek International, Inc. | Construction of chimera PRRSV, compositions and vaccine preparations |
JP2010531143A (ja) * | 2007-06-25 | 2010-09-24 | サウス ダコタ ステート ユニバーシティー | 組換え北アメリカ1型ブタ生殖器呼吸器症候群ウイルス及び使用方法 |
WO2010025109A1 (en) * | 2008-08-25 | 2010-03-04 | Boehringer Ingelheim Vetmedia, Inc. | Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (hp prrs) |
EP2230246A1 (en) * | 2009-03-19 | 2010-09-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Arterivirus glycoprotein 5 virus-like particles |
WO2010129674A2 (en) | 2009-05-05 | 2010-11-11 | New York University | Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins |
TWI627281B (zh) * | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物 |
ES2600929T3 (es) | 2009-09-10 | 2017-02-13 | Merial, Inc. | Nuevas formulaciones de vacuna que comprenden adyuvantes que contienen saponina |
CA2800824A1 (en) * | 2010-06-02 | 2011-12-08 | Virginia Tech Intellectual Properties, Inc. | Novel modified live-attenuated vaccines (mlv) and subunit vaccines created by dna shuffling against porcine reproductive and respiratory syndrome virus (prrsv) |
PL2675475T3 (pl) | 2011-02-17 | 2015-12-31 | Boehringer Ingelheim Vetmedica Gmbh | Nowy europejski szczep prrs |
US9944902B2 (en) | 2011-02-17 | 2018-04-17 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of PRRSV |
WO2013013056A1 (en) | 2011-07-19 | 2013-01-24 | New York University | Method for treating amyloid disease |
US9926353B2 (en) | 2011-07-19 | 2018-03-27 | New York University | Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides |
US9315781B2 (en) | 2011-07-29 | 2016-04-19 | Boehringer Ingelheim Vetmedica Gmbh | Infectious CDNA clone of european PRRS virus and uses thereof |
US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
DK2741740T3 (en) | 2011-08-12 | 2017-06-06 | Merial Inc | VACUUM-SUPPORTED CONSERVATION OF BIOLOGICAL PRODUCTS, IN PARTICULAR OF VACCINES |
UA114503C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
US10279028B2 (en) | 2012-04-24 | 2019-05-07 | Ohio State Innovation Foundation | Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome |
ES2932952T3 (es) | 2012-04-24 | 2023-01-30 | Ohio State Innovation Foundation | Composiciones y métodos para tratar y prevenir el síndrome reproductivo y respiratorio porcino |
RU2494760C1 (ru) * | 2012-04-26 | 2013-10-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ижевская государственная сельскохозяйственная академия" | Способ получения гипериммунной сыворотки против цирковирусной инфекции, репродуктивно-респираторного синдрома и гемофилеза свиней |
EP2968513A2 (en) | 2013-03-15 | 2016-01-20 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
MX2020010248A (es) | 2013-12-20 | 2020-10-16 | Boehringer Ingelheim Vetmedica Gmbh | Variante del virus prrs, clon de adnc del virus europeo y sus usos. |
TWI745278B (zh) | 2014-10-10 | 2021-11-11 | 以色列商艾畢克生物實驗有限公司 | 發泡性降低之疫苗組合物 |
CN104561092B (zh) * | 2014-12-19 | 2018-12-11 | 中国农业科学院上海兽医研究所 | 表达猪瘟病毒e2蛋白重组prrs病毒基因工程疫苗的构建方法和应用 |
KR20190044052A (ko) | 2016-06-17 | 2019-04-29 | 메리얼 인코포레이티드 | 선형 또는 분지형 폴리아크릴산 폴리머 아쥬반트를 포함하는 신규한 면역원성 제형 |
DK3534939T3 (da) | 2016-11-03 | 2023-04-24 | Boehringer Ingelheim Vetmedica Gmbh | Vaccine mod porcin parvovirus og porcin reproduktions- og respirationssyndromvirus og fremgangsmåder til fremstilling deraf |
CN113684318A (zh) * | 2021-09-16 | 2021-11-23 | 天津农学院 | 猪繁殖与呼吸综合征病毒m蛋白基因的荧光pcr检测试剂盒 |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4442205A (en) * | 1981-09-22 | 1984-04-10 | The United States Of America As Represented By The Department Of Health And Human Services | Simian virus recombinant that directs the synthesis of hepatitis B surface antigen |
US5213759A (en) * | 1988-05-05 | 1993-05-25 | Elopak Systems A.G. | Sterilization |
US5212057A (en) * | 1988-10-26 | 1993-05-18 | University Of Florida | Biological system for constructing and testing viral vaccines |
US5431160A (en) * | 1989-07-19 | 1995-07-11 | University Of New Mexico | Miniature implantable refillable glucose sensor and material therefor |
US5213795A (en) * | 1990-10-24 | 1993-05-25 | Oxford | Encephalomyocarditis virus vaccine |
CA2103460C (en) * | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
US5846805A (en) * | 1991-08-26 | 1998-12-08 | Boehringer Ingelheim Animal Health, Inc. | Culture of swine infertility and respiratory syndrome virus in simian cells |
ATE144144T1 (de) * | 1991-08-26 | 1996-11-15 | James Edward Collins | Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas) |
US6042830A (en) * | 1992-08-05 | 2000-03-28 | Boehringer Ingelheim Vetmedica, Inc. | Viral agent associated with mystery swine disease |
CA2076744C (en) * | 1991-08-26 | 2000-06-27 | Danny W. Chladek | Viral agent associated with mystery swine disease |
WO1993006211A1 (en) * | 1991-09-16 | 1993-04-01 | Collins James E | Vaccine for mystery swine disease and method for diagnosis thereof |
EP0610250B2 (en) * | 1991-10-14 | 2008-10-29 | Intervet International BV | Porcine reproductive respiratory syndrome (prrs) vaccine and diagnostic |
FR2686097B1 (fr) * | 1992-01-14 | 1994-12-30 | Rhone Merieux | Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie. |
TW289731B (pt) * | 1992-07-09 | 1996-11-01 | Akzo Nv | |
US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
US5695766A (en) | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
US6251397B1 (en) | 1992-10-30 | 2001-06-26 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same |
US5419907A (en) * | 1992-11-10 | 1995-05-30 | Iowa State University Research Foundation, Inc. | Pathogenic porcine respiratory coronavirus |
CZ289743B6 (cs) * | 1993-02-08 | 2002-03-13 | Bayer Corporation | Izolát viru vepřového reprodukčního a respiračního syndromu PRRSV, způsob kultivace PRRSV, tkáňová kultura, způsob přípravy vakcíny a vakcína obsahující PRRSV izolát |
ES2074950B1 (es) | 1993-09-17 | 1996-03-16 | Iberica Cyanamid | Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda. |
EP0659885A1 (en) * | 1993-12-21 | 1995-06-28 | Akzo Nobel N.V. | Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity |
DE4407489A1 (de) * | 1994-03-07 | 1995-09-14 | Bayer Ag | Vakzine zur Prävention von Respirations- und Reproduktionserkrankungen des Schweines |
ES2165405T3 (es) * | 1994-04-11 | 2002-03-16 | Akzo Nobel Nv | Cepas de vacuna europeas del virus del sindrome reproductor y respiratorio porcino (prrsv). |
GB2289279B (en) * | 1994-05-13 | 1998-09-16 | Iberica Cyanamid | Diagnostic kits and vaccines containing recombinant PRRSV proteins |
DE69535061T2 (de) | 1994-08-05 | 2007-01-25 | Regents Of The University Of Minnesota, Minneapolis | Virale nukleotidsequenz vr-2332 und nutzungsverfahren |
ATE268783T1 (de) * | 1995-03-14 | 2004-06-15 | Akzo Nobel Nv | Expression in der selben zelle von polypeptide vom schweinen reproduktiven und respiratorischen syndrom |
ES2102971B1 (es) * | 1996-01-25 | 1998-03-01 | Hipra Lab Sa | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion. |
US6015663A (en) * | 1996-03-01 | 2000-01-18 | The United States Of America As Represented By The Secretary Of Agriculture | Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains |
US5866401A (en) * | 1996-03-01 | 1999-02-02 | Schering Corporation | Porcine reproductive and respiratory syndrome vaccine |
US5976537A (en) * | 1996-07-02 | 1999-11-02 | The United States Of America As Represented By The Secretary Of Agriculture | Porcine reproductive and respiratory syndrome vaccine |
PT835930E (pt) * | 1996-10-09 | 2001-06-29 | Akzo Nobel Nv | Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv) |
DE69837992T2 (de) * | 1997-05-06 | 2008-03-20 | Boehringer Ingelheim Vetmedica Gmbh | Prrsv-antigene, die auf peptidsequenzen des prrs-virus basieren, für die verwendung als impfstoff und für diagnostische tests |
US5970537A (en) * | 1998-02-03 | 1999-10-26 | Hickory Springs Manufacturing Co. | Folding bed frame structure and method of fabricating same |
US6403102B1 (en) * | 1998-10-29 | 2002-06-11 | Connaught Laboratories Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
-
1993
- 1993-10-05 US US08/131,625 patent/US5695766A/en not_active Expired - Lifetime
- 1993-10-29 ES ES93203042T patent/ES2286815T3/es not_active Expired - Lifetime
- 1993-10-29 CA CA 2102036 patent/CA2102036C/en not_active Expired - Lifetime
- 1993-10-29 DE DE1993634141 patent/DE69334141T2/de not_active Expired - Lifetime
- 1993-10-29 EP EP19930203042 patent/EP0595436B1/en not_active Expired - Lifetime
- 1993-10-29 AU AU50375/93A patent/AU672825B2/en not_active Withdrawn - After Issue
- 1993-10-29 MX MXPA93006804A patent/MXPA93006804A/es not_active IP Right Cessation
- 1993-10-29 DK DK93203042T patent/DK0595436T3/da active
- 1993-10-30 CN CN93120704A patent/CN1087175C/zh not_active Expired - Lifetime
- 1993-11-01 JP JP29608593A patent/JP4125385B2/ja not_active Expired - Lifetime
- 1993-11-01 BR BR9304453A patent/BR9304453A/pt not_active Application Discontinuation
- 1993-12-11 TW TW82110515A patent/TW517085B/zh not_active IP Right Cessation
- 1993-12-11 TW TW86101249A patent/TW497973B/zh not_active IP Right Cessation
-
1997
- 1997-05-13 US US08/855,531 patent/US6110467A/en not_active Expired - Lifetime
- 1997-05-13 US US08/855,526 patent/US6251404B1/en not_active Expired - Fee Related
-
2006
- 2006-03-08 US US11/369,944 patent/US7517976B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0595436B1 (en) | 2007-05-23 |
EP0595436A2 (en) | 1994-05-04 |
US20070269445A1 (en) | 2007-11-22 |
CN1087175C (zh) | 2002-07-10 |
JP4125385B2 (ja) | 2008-07-30 |
JPH07138186A (ja) | 1995-05-30 |
CN1096223A (zh) | 1994-12-14 |
ES2286815T3 (es) | 2007-12-01 |
DE69334141D1 (de) | 2007-07-05 |
AU5037593A (en) | 1994-05-12 |
DE69334141T2 (de) | 2008-01-24 |
US6110467A (en) | 2000-08-29 |
AU672825B2 (en) | 1996-10-17 |
EP0595436A3 (en) | 1994-11-23 |
US7517976B2 (en) | 2009-04-14 |
CA2102036A1 (en) | 1994-05-01 |
MXPA93006804A (es) | 2003-05-30 |
TW497973B (en) | 2002-08-11 |
TW517085B (en) | 2003-01-11 |
CA2102036C (en) | 2004-02-24 |
US5695766A (en) | 1997-12-09 |
DK0595436T3 (da) | 2007-09-03 |
US6251404B1 (en) | 2001-06-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9304453A (pt) | Vacina e processo para sua produçao, amostra biologicamente pura de um vírus ou agente infeccioso, composiçao e processo para proteger um porco contra infecçao viral, anticorpo, processo para tratar um porco sofrendo de uma doença respiratório e de reproduçao dos suínos, kit diagnóstico, polinucleotídio, proteína, ácido polinucleico isolado e processo para cultivar um vírus | |
EP1016418A3 (en) | Composition comprising a recombinant virus expressing an antigen and a recombinant virus expressing an immunostimulatory molecule | |
PT93393A (pt) | Processo para a preparacao de vacinas e de agentes de diagnostico que contem regioes imunogenicas de proteina e7do virus do papiloma humano do tipo 16 ou anticorpos suscitados contra estas regioes | |
DE69536039D1 (de) | Wirtszelle enthaltend ein rekombinantes Virus, welches ein Antigen exprimiert und ein rekombinantes Virus, welches ein immunstimulatorisches Molekül exprimiert | |
BR1100637A (pt) | "vìrus de herpes de perus (hvt) recombinante, hvt recombinante, sequência de ácido nucléico, molécupara a preparação de um hvt recombinante, cultura uma vacina, processo para a preparação de uma composição de vacina, farmacêutica ou diagnóstica e anti-soro" | |
HUP9903822A2 (hu) | Polinukleotid-vakcinakészítmény sertések szaporodásbiológiai és légzőszervi kórképei ellen | |
BR9505938A (pt) | Composto processo para sua preparação processos para tratamento e prevenção de doenças processo de elevação dos níveis de HDL plasmático e composiç o farmacêutica | |
IE862276L (en) | PREVENTION AND TREATMENT OF AIDS WITH dsRNA | |
DE69815122T2 (de) | Saccharid-enthaltende zubereitungen zur behandlung von alzheimerschen erkrankung und von weiteren amyloidosen | |
ES2065303T3 (es) | Procedimiento de diagnosis y vacuna especifica. | |
DE69637914D1 (de) | Impstoff gegen den für atemwegs- und reproduktionserkrankungen beim schwein verantwortlichen virus | |
BR0111366A (pt) | Vacina de poxvìrus recombinante do vìrus da sìndrome respiratória e reprodutiva de porcino (prrsv) | |
CA2160764A1 (en) | Fish pancreatic disease virus | |
EP0138720A3 (fr) | Nouveaux benzenesulfonamides n-cyclises, leur procédé de préparation et leur utilisation comme substance active de compositions pharmaceutiques | |
US5304636A (en) | Receptor for the human rhinovirus minor group | |
DK0588118T3 (da) | Carboxypeptidaselignende protein knyttet til knogler samt fremgangsmåde til fremstilling deraf | |
BR9407862A (pt) | Composto de flavina flavina derivado de flavina ou uma mistura que compreende duas ou mais destas composiçao farmacêutica e processo para o tratamento por profilaxia ou terapia de doença causada por infecçao virótica | |
Docherty et al. | Inactivation of herpes simplex virus types 1 and 2 by synthetic histidine peptides | |
DK0585801T3 (da) | Konoglerelateret protein af cadherin-typen og fremgangsmåde til dets fremstilling | |
BR0108442A (pt) | Mutantes-ehv gm-negativos | |
PT1206488E (pt) | Processo para o isolamento e para a purificacao de alergenios de polens das gramineas | |
DK0590309T3 (da) | Knoglevævsbeslægtet protein, fremgangsmåde til dets fremstilling samt lægemiddel med indhold deraf | |
Wittmann et al. | Occurrence of clinical Aujeszky’s disease in immunosuppressed latently infected pigs | |
FR2792639B1 (fr) | Nouveaux immunogenes anti-vih (toxoides), nouveaux procedes de preparation et application a la prevention et au traitement du sida | |
RU2157693C1 (ru) | Способ лечения вирусных болезней у животных |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EE | Request for examination | ||
FA | Application withdrawn | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C07K 14/005 (2006.01), A61K 39/12 (2006.0 |