BR112019012210A2 - formas cristalinas de um inibidor de janus cinase - Google Patents
formas cristalinas de um inibidor de janus cinase Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662437262P | 2016-12-21 | 2016-12-21 | |
| PCT/JP2017/045731 WO2018117153A1 (en) | 2016-12-21 | 2017-12-20 | Crystalline forms of a janus kinase inhibitor |
Publications (1)
| Publication Number | Publication Date |
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| BR112019012210A2 true BR112019012210A2 (pt) | 2019-11-12 |
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| BR112019012210-9A BR112019012210A2 (pt) | 2016-12-21 | 2017-12-20 | formas cristalinas de um inibidor de janus cinase |
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| EP (1) | EP3559003B1 (https=) |
| JP (3) | JP2020502224A (https=) |
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| MX (1) | MX386181B (https=) |
| TW (1) | TWI822666B (https=) |
| WO (1) | WO2018117153A1 (https=) |
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| AU2017384317C1 (en) | 2016-12-21 | 2022-06-30 | Japan Tobacco Inc. | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF |
| KR20220044288A (ko) * | 2019-08-07 | 2022-04-07 | 로토 세이야쿠 가부시키가이샤 | 누액 분비 촉진용 안과 조성물 |
| CN111606929B (zh) * | 2020-06-30 | 2023-07-07 | 中瀚(齐河县)生物医药科技有限公司 | 德高替尼的制备方法 |
| JP7807247B2 (ja) * | 2021-02-05 | 2026-01-27 | ロート製薬株式会社 | シェーグレン症候群治療剤 |
| KR20240027044A (ko) * | 2021-07-30 | 2024-02-29 | 일라이 릴리 앤드 캄파니 | 바리시티닙을 사용한 손 습진의 치료 |
| WO2024180493A1 (en) * | 2023-02-28 | 2024-09-06 | Assia Chemical Industries Ltd. | Solid state forms of delgocitinib and process thereof |
| WO2024225445A1 (en) * | 2023-04-27 | 2024-10-31 | Japan Tobacco Inc. | Crystalline form of delgocitinib |
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| US20090296332A1 (en) * | 2005-07-07 | 2009-12-03 | Thomson Licensing | Flat-Screen Display System With Corresponding Sleeves |
| EP2108641A1 (en) * | 2008-04-11 | 2009-10-14 | Laboratorios Almirall, S.A. | New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors |
| SG176111A1 (en) * | 2009-05-22 | 2011-12-29 | Incyte Corp | 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors |
| TWI466885B (zh) * | 2009-07-31 | 2015-01-01 | Japan Tobacco Inc | 含氮螺環化合物及其醫藥用途 |
| GB201004200D0 (en) * | 2010-03-15 | 2010-04-28 | Univ Basel | Spirocyclic compounds and their use as therapeutic agents and diagnostic probes |
| US20140343034A1 (en) * | 2013-04-25 | 2014-11-20 | Japan Tobacco Inc. | Skin barrier function improving agent |
| KR102306276B1 (ko) * | 2013-10-21 | 2021-09-30 | 니뽄 다바코 산교 가부시키가이샤 | 안질환의 치료제 또는 예방제 |
| HK1251223A1 (en) | 2015-07-07 | 2019-01-25 | Japan Tobacco, Inc. | Method for producing 7h-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof |
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2017
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- 2017-12-20 BR BR112019012210-9A patent/BR112019012210A2/pt not_active Application Discontinuation
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2019
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2022
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2024
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Also Published As
| Publication number | Publication date |
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| CN110325536A (zh) | 2019-10-11 |
| EP3559003A1 (en) | 2019-10-30 |
| RU2019122566A (ru) | 2021-01-22 |
| CA3044771A1 (en) | 2018-06-28 |
| IL267393B1 (en) | 2023-03-01 |
| RU2019122566A3 (https=) | 2021-12-22 |
| EP3559003B1 (en) | 2022-08-24 |
| IL267393A (en) | 2019-08-29 |
| IL267393B2 (en) | 2023-07-01 |
| CN121045220A (zh) | 2025-12-02 |
| KR102788829B1 (ko) | 2025-03-31 |
| KR20190092440A (ko) | 2019-08-07 |
| AU2017380213B2 (en) | 2022-01-06 |
| MX2019007462A (es) | 2019-08-29 |
| JP2023024729A (ja) | 2023-02-16 |
| MX386181B (es) | 2025-03-18 |
| AU2017380213A1 (en) | 2019-05-23 |
| ES2926986T3 (es) | 2022-10-31 |
| JP2024161449A (ja) | 2024-11-19 |
| JP2020502224A (ja) | 2020-01-23 |
| TW201829423A (zh) | 2018-08-16 |
| WO2018117153A1 (en) | 2018-06-28 |
| US20200017527A1 (en) | 2020-01-16 |
| US11339181B2 (en) | 2022-05-24 |
| TWI822666B (zh) | 2023-11-21 |
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