BR112018014122A2 - imunoensaio para o diagnóstico de infecções virais - Google Patents
imunoensaio para o diagnóstico de infecções viraisInfo
- Publication number
- BR112018014122A2 BR112018014122A2 BR112018014122A BR112018014122A BR112018014122A2 BR 112018014122 A2 BR112018014122 A2 BR 112018014122A2 BR 112018014122 A BR112018014122 A BR 112018014122A BR 112018014122 A BR112018014122 A BR 112018014122A BR 112018014122 A2 BR112018014122 A2 BR 112018014122A2
- Authority
- BR
- Brazil
- Prior art keywords
- seq
- immunoassay
- diagnosis
- individual
- viral infections
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000003018 immunoassay Methods 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
- 239000000539 dimer Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
- G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
- G01N2333/185—Flaviviruses or Group B arboviruses, e.g. yellow fever virus, japanese encephalitis, tick-borne encephalitis, dengue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
a presente invenção refere-se a um polipeptídeo, preferivelmente um dímero e/ou hexâmero do mesmo, mais preferivelmente um dímero, compreendendo uma sequência selecionada a partir do grupo compreendendo seq id no1, seq id no2, seq id no3, seq id no4, seq id no5, seq id no6, seq id no7, seq id no8, seq id no19 e seq id no9 ou uma variante das mesmas, preferivelmente seq id no1 ou uma variante da mesma, para o diagnóstico de uma doença, um veículo diagnosticamente útil compreendendo um meio para especificamente capturar um anticorpo para seq id no1 em uma amostra a partir de um indivíduo, um kit compreendendo o veículo diagnosticamente útil, e um método, preferivelmente para diagnosticar uma doença, compreendendo a etapa de detecção em uma amostra a partir de um indivíduo da presença ou ausência de um anticorpo para seq id no1.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16000422 | 2016-02-22 | ||
| EP16000442 | 2016-02-24 | ||
| EP16000454 | 2016-02-25 | ||
| EP16000747 | 2016-03-31 | ||
| PCT/EP2017/000249 WO2017144174A1 (en) | 2016-02-22 | 2017-02-22 | An immunoassay for the diagnosis of viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018014122A2 true BR112018014122A2 (pt) | 2018-12-11 |
Family
ID=58162500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018014122A BR112018014122A2 (pt) | 2016-02-22 | 2017-02-22 | imunoensaio para o diagnóstico de infecções virais |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10837963B2 (pt) |
| EP (1) | EP3420357B1 (pt) |
| CN (2) | CN108650889B (pt) |
| BR (1) | BR112018014122A2 (pt) |
| DE (1) | DE112017000924T5 (pt) |
| ES (1) | ES2971274T3 (pt) |
| SG (1) | SG11201805496PA (pt) |
| WO (2) | WO2017144173A1 (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020517647A (ja) | 2017-04-26 | 2020-06-18 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 可溶性および免疫反応性のジカウイルスｎｓ１ポリペプチド |
| EP3530668A1 (en) | 2018-02-22 | 2019-08-28 | Euroimmun Medizinische Labordiagnostika AG | A novel assay for the diagnosis of viral infections |
| US11292816B2 (en) | 2018-02-22 | 2022-04-05 | Euroimmun Medizinische Labordiagnostika Ag | Assay for the diagnosis of viral infections |
| CN113651886B (zh) * | 2018-04-04 | 2022-04-15 | 中国科学院微生物研究所 | 一种高灵敏度的黄热病毒人源单克隆抗体及其应用 |
| CN108707191B (zh) * | 2018-07-09 | 2020-08-25 | 江西农业大学 | 一种乙型脑炎病毒非结构蛋白ns1截短突变体及其编码基因和应用 |
| AU2019310347A1 (en) * | 2018-07-23 | 2021-03-04 | The University Of Adelaide | Zika virus vaccine |
| BR102018067345A2 (pt) * | 2018-08-31 | 2020-03-10 | Inst Butantan | processo de produção de proteína recombinante, produto obtido pelo processo e seu uso no diagnóstico do vírus zika |
| WO2020092564A1 (en) * | 2018-10-31 | 2020-05-07 | Icahn School Of Medicine At Mount Sinai | Human antibodies targeting zika virus ns1, ns1 polypeptides and uses thereof |
| US20200191785A1 (en) * | 2018-12-18 | 2020-06-18 | Euroimmun Medizinische Labordiagnostika Ag | Method for Diagnosing Autoimmune Gastritis |
| JP2020122773A (ja) * | 2019-01-31 | 2020-08-13 | 田中貴金属工業株式会社 | デングウイルス検出用免疫クロマト分析装置 |
| AU2020356408A1 (en) * | 2019-09-25 | 2022-03-31 | Centre National De La Recherche Scientifique - Cnrs - | A novel complex formed between the flaviviral non-structural NS1 protein and plasma lipoproteins |
| CN111944153B (zh) * | 2020-08-11 | 2022-08-26 | 华南师范大学 | 一种用于检测登革热ns1蛋白的分子印迹聚合物微球及其应用 |
| CN116425840B (zh) * | 2023-05-15 | 2023-10-27 | 中山大学 | 一种特异性多肽及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01501203A (ja) * | 1986-10-27 | 1989-04-27 | フォーニアー，モーリル・ジェイ | 日本脳炎ウイルス及び類似ウイルスの診断及びワクチン |
| US5670310A (en) * | 1994-07-29 | 1997-09-23 | The United States Of America As Represented By The Department Of Health And Human Services | Methods and compositions for differential diagnosis of acute and chronic hepatitis c virus infection |
| FR2794865B1 (fr) * | 1999-06-09 | 2003-04-18 | Pasteur Institut | Methode de detection precoce des flavivirus et ses applications |
| KR20060117691A (ko) * | 2005-05-13 | 2006-11-17 | 삼성전자주식회사 | 대상의 유형에 따른 심혈관 질환 진단용 ｓｎｐ, 그를포함하는 마이크로어레이 및 키트 및 그를 이용한 심혈관질환 진단 방법 |
| SG137711A1 (en) * | 2006-05-11 | 2007-12-28 | Nat Environment Agency | Antigen capture anti-dengue iga elisa (aca-elisa) for the detection of a flavivirus specific antibody |
| DE202011106093U1 (de) | 2011-09-24 | 2011-10-19 | Euroimmun Medizinische Labordiagnostika Ag | Kalibrationsstreifen für einen Immunoblot |
| CN102432676A (zh) * | 2011-09-30 | 2012-05-02 | 中国人民解放军广州军区疾病预防控制中心 | 一种检测登革病毒抗体的重组抗原蛋白、试剂盒及其应用 |
| EP2799877A1 (en) * | 2013-05-03 | 2014-11-05 | Universität Ulm | Process for diagnosing a human subject with diseases affecting the kidneys, or at risk of acquiring diseases affecting the kidneys |
| WO2015095735A2 (en) * | 2013-12-20 | 2015-06-25 | The Regents Of The University Of Michigan | Vaccine compositions and uses thereof |
| EP2980099A1 (en) | 2014-07-31 | 2016-02-03 | Bernhard-Nocht-Institut für Tropenmedizin | Compositions and methods for detecting flaviviridae infections |
| SG10201404571PA (en) * | 2014-08-01 | 2016-03-30 | Mp Biomedicals Asia Pacific Pte Ltd | Method and kit for detecting a dengue virus infection |
| EP3322441A4 (en) * | 2015-07-16 | 2018-12-19 | Bharat Biotech International Limited | Vaccine compositions |
-
2017
- 2017-02-22 BR BR112018014122A patent/BR112018014122A2/pt unknown
- 2017-02-22 CN CN201780010007.3A patent/CN108650889B/zh active Active
- 2017-02-22 US US16/077,757 patent/US10837963B2/en active Active
- 2017-02-22 WO PCT/EP2017/000248 patent/WO2017144173A1/en active Application Filing
- 2017-02-22 ES ES17707171T patent/ES2971274T3/es active Active
- 2017-02-22 WO PCT/EP2017/000249 patent/WO2017144174A1/en active Application Filing
- 2017-02-22 EP EP17707171.9A patent/EP3420357B1/en active Active
- 2017-02-22 SG SG11201805496PA patent/SG11201805496PA/en unknown
- 2017-02-22 CN CN201780010002.0A patent/CN108633305B/zh active Active
- 2017-02-22 DE DE112017000924.3T patent/DE112017000924T5/de active Pending
-
2020
- 2020-10-01 US US16/948,825 patent/US11828758B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20210033609A1 (en) | 2021-02-04 |
| WO2017144173A1 (en) | 2017-08-31 |
| CN108650889B (zh) | 2022-06-10 |
| US20190383814A1 (en) | 2019-12-19 |
| CN108650889A (zh) | 2018-10-12 |
| CN108633305A (zh) | 2018-10-09 |
| EP3420357C0 (en) | 2023-12-20 |
| ES2971274T3 (es) | 2024-06-04 |
| EP3420357A1 (en) | 2019-01-02 |
| DE112017000924T5 (de) | 2019-03-07 |
| US11828758B2 (en) | 2023-11-28 |
| US10837963B2 (en) | 2020-11-17 |
| CN108633305B (zh) | 2022-04-12 |
| EP3420357B1 (en) | 2023-12-20 |
| SG11201805496PA (en) | 2018-07-30 |
| WO2017144174A1 (en) | 2017-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112018014122A2 (pt) | imunoensaio para o diagnóstico de infecções virais | |
| EA200971114A1 (ru) | Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител | |
| BR112012010108A2 (pt) | métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável | |
| EA201792497A1 (ru) | Антитела к gitr для диагностики злокачественной опухоли | |
| JP2016105097A5 (pt) | ||
| BR112017004899A2 (pt) | detecção de proteínas mal dobradas | |
| EA201590459A1 (ru) | Специфические антитела к островковому амилоидному полипептиду человека (hiapp) и их применение | |
| BR112019005172A2 (pt) | método e kit para analisar uma amostra | |
| BR112019005167A2 (pt) | método e kit para analisar uma amostra | |
| BR112014020513A2 (pt) | Métodos e sistemas para amplificação de sinal de bioensaios | |
| BR112016016737A2 (pt) | Peptídeos, dispositivos e métodos para detecção de anticorpos contra anaplasma | |
| PE20220004A1 (es) | Anticuerpos monoclonales especificos para el antigeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, utiles para la deteccion y el diagnostico de la infeccion causada por vrsh | |
| AR105379A1 (es) | Dispositivo para detectar proteínas mal plegadas y sus métodos de uso | |
| WO2017125892A3 (es) | Anticuerpos monoclonales específicos para el antígeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por adv | |
| WO2011109112A3 (en) | Method of detecting tau protein and tau fragments in serum | |
| WO2016135246A3 (en) | Antibody detection method and system | |
| EP4257976A3 (en) | Mycobacterium tuberculosis proteins in diagnostic assays and devices for tuberculosis detection and diagnosis | |
| BR112019005179A2 (pt) | método e kit para analisar uma amostra | |
| AR083241A1 (es) | Metodos y kits para el diagnostico de cancer de prostata | |
| TR201007549A2 (tr) | Emici boncuklar ile santrifüje gereksinimi ortadan kaldıran yoğunlaştırma yöntemi ve kitleri. | |
| EA201991843A1 (ru) | Способ иммунологического определения специфических антител к антигенам вирусов семейства поксвирусов | |
| Ong et al. | Cloning, expression, and purification of the hemolysin/cytolysin (HlyE antigen) from Salmonella enterica serovar Typhi: potential application for immunoassay development | |
| BR112017007592A2 (pt) | polipeptídeo, composição de polipeptídeos, métodos de produção de polipeptídeo e de detecção de anticorpos, uso de polipeptídeo e kit de reagentes | |
| BR112021025089A2 (pt) | Antígenos secretados inovadores para diagnóstico de infecção ativa por babesia microti e babesia duncani em humanos e animais | |
| RU2017120228A (ru) | Особые моноклональные антитела антигена м метапневмовируса человека (hmpv) и способ их использования в методе диагностики |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |