BR112012010108A2 - métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável - Google Patents

métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável

Info

Publication number
BR112012010108A2
BR112012010108A2 BR112012010108A BR112012010108A BR112012010108A2 BR 112012010108 A2 BR112012010108 A2 BR 112012010108A2 BR 112012010108 A BR112012010108 A BR 112012010108A BR 112012010108 A BR112012010108 A BR 112012010108A BR 112012010108 A2 BR112012010108 A2 BR 112012010108A2
Authority
BR
Brazil
Prior art keywords
bowel syndrome
irritable bowel
methods
serum
regression
Prior art date
Application number
BR112012010108A
Other languages
English (en)
Inventor
Hua Gong
Sharat Singh
Shui Long Wang
Original Assignee
Prometheus Laboratoires Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometheus Laboratoires Inc filed Critical Prometheus Laboratoires Inc
Publication of BR112012010108A2 publication Critical patent/BR112012010108A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

Abstract

métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do instestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável. a invenção fornece novos biomarcadores, kits e métodos de diagnosticar, prognosticar e subtipar ibs. tmabém são fornecidos métodos para auxiliar do diagnóstico da síndrome do intestino irritável pela detecção do nível sérico dos novos biomarcadores de ibs aqui identificados.
BR112012010108A 2009-10-30 2010-10-29 métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável BR112012010108A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25671709P 2009-10-30 2009-10-30
US26458809P 2009-11-25 2009-11-25
US32617610P 2010-04-20 2010-04-20
PCT/US2010/054810 WO2011053831A1 (en) 2009-10-30 2010-10-29 Methods for diagnosing irritable bowel syndrome

Publications (1)

Publication Number Publication Date
BR112012010108A2 true BR112012010108A2 (pt) 2016-05-31

Family

ID=43922588

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012010108A BR112012010108A2 (pt) 2009-10-30 2010-10-29 métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável

Country Status (13)

Country Link
US (1) US20120315630A1 (pt)
EP (1) EP2494074A4 (pt)
JP (1) JP2013509593A (pt)
KR (1) KR20120101038A (pt)
CN (1) CN102712956A (pt)
AU (1) AU2010313292A1 (pt)
BR (1) BR112012010108A2 (pt)
CA (1) CA2778539A1 (pt)
IL (1) IL219317A0 (pt)
MX (1) MX2012005015A (pt)
RU (1) RU2012122180A (pt)
WO (1) WO2011053831A1 (pt)
ZA (1) ZA201203718B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5857503B2 (ja) * 2010-07-29 2016-02-10 小野薬品工業株式会社 ストレス性疾患のバイオマーカー
WO2012158831A1 (en) 2011-05-16 2012-11-22 Prometheus Laboratories Inc. Performance of a biomarker panel for irritable bowel syndrome
EA201401286A1 (ru) * 2012-05-19 2015-04-30 Др. Фальк Фарма Гмбх Композиции и способы для лечения синдрома раздраженной толстой кишки с помощью 5-аминосалицилата
JP6329553B2 (ja) * 2012-10-05 2018-05-23 ネステク ソシエテ アノニム Ｉｂｓの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー
WO2014082034A1 (en) * 2012-11-26 2014-05-30 Lexicon Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome
CN103175971B (zh) * 2013-02-28 2016-10-05 苏州和锐医药科技有限公司 一种IgA抗体检测试剂盒
CN106574919B (zh) * 2013-03-15 2020-11-03 赛拉预测公司 用于预测早产的生物标志物和方法
GB201305708D0 (en) * 2013-03-28 2013-05-15 Clasado Inc Novel use
AU2014269961A1 (en) * 2013-05-24 2015-11-26 Société des Produits Nestlé S.A. Pathway specific markers for diagnosing irritable bowel syndrome
EP3086846B1 (en) * 2013-12-27 2019-02-20 Dignity Health Diagnosing alzheimer's disease
JP6713723B2 (ja) * 2014-02-18 2020-06-24 小野薬品工業株式会社 過敏性腸症候群の診断用バイオマーカー
CN108450003B (zh) 2015-06-19 2022-04-01 赛拉预测公司 用于预测早产的生物标志物对
CN106446599A (zh) * 2015-08-11 2017-02-22 中国科学院青岛生物能源与过程研究所 一种筛选婴幼儿龋病的口腔致病性生物标记物的方法
CN105687225B (zh) * 2016-02-26 2018-07-06 四川好医生攀西药业有限责任公司 一种治疗肠易激综合征的药物组合物及其制备方法和应用
GB201605110D0 (en) * 2016-03-24 2016-05-11 Mologic Ltd Detecting sepsis
US10817778B2 (en) 2016-06-27 2020-10-27 International Business Machines Corporation Customized cooking utilizing deep learning neuromorphic computing of hyperspectral input
MX2019002918A (es) * 2016-09-16 2019-07-18 Dyax Corp Biomarcadores de metabolitos para enfermedades asociadas con el sistema de activacion por contacto.
RU2668496C2 (ru) * 2017-03-16 2018-10-01 Государственное бюджетное учреждение здравоохранения города Москвы Московский клинический научно-практический центр Департамента здравоохранения города Москвы Способ диагностики тяжести течения синдрома раздраженного кишечника
CN106990057A (zh) * 2017-05-05 2017-07-28 贵州普洛迈德生物工程有限公司 一种检测5‑羟吲哚乙酸试剂及制备方法
EP3668996A4 (en) 2017-08-18 2021-04-21 Sera Prognostics, Inc. CLOCK PREGNANCY PROTEIN FOR PREDICTING THE DATE AND TIME TO BIRTH
US11488699B1 (en) 2018-12-09 2022-11-01 Cerner Innovation, Inc. Microbiota activity sensor and decision support tool
US11842795B1 (en) * 2018-12-17 2023-12-12 Cerner Innovation, Inc. Irritable bowel syndrome diagnostic sensor and decision support tool
KR102330639B1 (ko) * 2019-01-18 2021-11-24 주식회사 천랩 과민성대장증후군 특이적 미생물 바이오마커와 이를 이용하여 과민성대장증후군의 위험도를 예측하는 방법
US20220146527A1 (en) * 2019-09-17 2022-05-12 Chang Gung University Method of creating characteristic profiles of mass spectra and identification model for analyzing and identifying features of microorganisms
CN112921100A (zh) * 2019-12-06 2021-06-08 宁波海尔施基因科技有限公司 一种检测人类压力敏感度基因型的试剂盒和方法
EP3913371A1 (en) * 2020-05-18 2021-11-24 Neuroimmun GmbH Method and kit for diagnosting irritable bowel syndrome and for its relief through dietary interventions
CN111784683B (zh) * 2020-07-10 2022-05-17 天津大学 病理切片检测方法及装置、计算机设备及存储介质
CN111905111B (zh) * 2020-09-16 2023-03-31 地奥集团成都药业股份有限公司 一种评价复方谷氨酰胺组方对腹泻型肠易激综合征疗效的方法
CN115328117B (zh) * 2022-07-15 2023-07-14 大理大学 基于强化学习的蛋白质动态配体通道最优路径分析方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3786299A (en) * 1998-05-04 1999-11-23 Neotherapeutics, Inc. Novel serotonin-like 9-substituted hypoxanthine and methods of use
JP2004508056A (ja) * 2000-09-06 2004-03-18 グラクソ　グループ　リミテッド ５−ヒドロキシトリプタミン受容体遺伝子多型、および治療に対する応答
US20080085524A1 (en) * 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
AU2010266028B2 (en) * 2009-06-25 2015-04-30 Société des Produits Nestlé S.A. Methods for diagnosing irritable bowel syndrome

Also Published As

Publication number Publication date
MX2012005015A (es) 2012-06-12
KR20120101038A (ko) 2012-09-12
ZA201203718B (en) 2014-11-26
AU2010313292A1 (en) 2012-06-07
US20120315630A1 (en) 2012-12-13
EP2494074A1 (en) 2012-09-05
RU2012122180A (ru) 2013-12-10
EP2494074A4 (en) 2013-06-12
CA2778539A1 (en) 2011-05-05
CN102712956A (zh) 2012-10-03
JP2013509593A (ja) 2013-03-14
IL219317A0 (en) 2012-06-28
WO2011053831A1 (en) 2011-05-05

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B25B Requested transfer of rights rejected

Owner name: PROMETHEUS LABORATOIRES INC. (US)