BR112017011788A2 - composições anticâncer - Google Patents

composições anticâncer

Info

Publication number
BR112017011788A2
BR112017011788A2 BR112017011788A BR112017011788A BR112017011788A2 BR 112017011788 A2 BR112017011788 A2 BR 112017011788A2 BR 112017011788 A BR112017011788 A BR 112017011788A BR 112017011788 A BR112017011788 A BR 112017011788A BR 112017011788 A2 BR112017011788 A2 BR 112017011788A2
Authority
BR
Brazil
Prior art keywords
prostate cancer
hpmcas
castration resistant
amn
arn
Prior art date
Application number
BR112017011788A
Other languages
English (en)
Portuguese (pt)
Inventor
Martin Hester Dennis
Michael VAUGHN Jason
Original Assignee
Aragon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52006906&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017011788(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aragon Pharmaceuticals Inc filed Critical Aragon Pharmaceuticals Inc
Publication of BR112017011788A2 publication Critical patent/BR112017011788A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR112017011788A 2014-12-05 2015-12-03 composições anticâncer BR112017011788A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14196594 2014-12-05
PCT/US2015/063661 WO2016090098A1 (en) 2014-12-05 2015-12-03 Anticancer compositions

Publications (1)

Publication Number Publication Date
BR112017011788A2 true BR112017011788A2 (pt) 2017-12-26

Family

ID=52006906

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017011788A BR112017011788A2 (pt) 2014-12-05 2015-12-03 composições anticâncer

Country Status (29)

Country Link
US (3) US20170360754A1 (enExample)
EP (2) EP4494636A3 (enExample)
JP (2) JP6937692B2 (enExample)
KR (2) KR102348320B1 (enExample)
CN (2) CN106999431B (enExample)
AR (1) AR102926A1 (enExample)
AU (3) AU2015358490B2 (enExample)
BR (1) BR112017011788A2 (enExample)
CA (1) CA2969656A1 (enExample)
CL (1) CL2017001371A1 (enExample)
CO (1) CO2017005572A2 (enExample)
CR (1) CR20170216A (enExample)
EA (1) EA201791222A1 (enExample)
ES (1) ES2996833T3 (enExample)
HR (1) HRP20241719T1 (enExample)
HU (1) HUE069689T2 (enExample)
IL (2) IL252323B (enExample)
MA (1) MA41107B1 (enExample)
MD (1) MD3226841T2 (enExample)
MX (2) MX387933B (enExample)
NZ (1) NZ770528A (enExample)
PH (1) PH12017500964A1 (enExample)
PL (1) PL3226841T3 (enExample)
RS (1) RS66323B1 (enExample)
SG (1) SG11201704267VA (enExample)
SM (1) SMT202400518T1 (enExample)
TW (2) TWI754258B (enExample)
UA (1) UA120950C2 (enExample)
WO (1) WO2016090098A1 (enExample)

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US10702508B2 (en) 2017-10-16 2020-07-07 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer
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JP2023500935A (ja) 2019-11-04 2023-01-11 アラゴン ファーマシューティカルズ，インコーポレイテッド 重度の肝障害を有する対象における非転移性去勢抵抗性前立腺癌の治療のためのアンドロゲン受容体阻害剤
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Publication number Publication date
EP3226841A1 (en) 2017-10-11
UA120950C2 (uk) 2020-03-10
US12303493B2 (en) 2025-05-20
KR20200141533A (ko) 2020-12-18
CN106999431A (zh) 2017-08-01
US20240293374A1 (en) 2024-09-05
AU2015358490B2 (en) 2021-04-08
MA41107A (fr) 2017-10-10
CA2969656A1 (en) 2016-06-09
PH12017500964A1 (en) 2017-10-18
RS66323B1 (sr) 2025-01-31
NZ770528A (en) 2024-03-22
WO2016090098A1 (en) 2016-06-09
US20230233529A1 (en) 2023-07-27
HUE069689T2 (hu) 2025-04-28
MX387933B (es) 2025-03-19
JP2020143069A (ja) 2020-09-10
IL279833B (en) 2022-03-01
US20170360754A1 (en) 2017-12-21
NZ731963A (en) 2024-03-22
TWI754258B (zh) 2022-02-01
EP3226841B1 (en) 2024-10-09
HRP20241719T1 (hr) 2025-02-14
EP4494636A2 (en) 2025-01-22
CN114886852A (zh) 2022-08-12
AU2021201979A1 (en) 2021-04-29
IL252323A0 (en) 2017-07-31
ES2996833T3 (en) 2025-02-13
AR102926A1 (es) 2017-04-05
SMT202400518T1 (it) 2025-01-14
JP7174006B2 (ja) 2022-11-17
IL279833A (en) 2021-01-31
JP2017536398A (ja) 2017-12-07
MA41107B1 (fr) 2025-01-31
AU2021201979B2 (en) 2023-02-02
KR102348320B1 (ko) 2022-01-10
IL252323B (en) 2021-04-29
CL2017001371A1 (es) 2018-01-05
CR20170216A (es) 2017-08-30
CN106999431B (zh) 2022-03-04
PL3226841T3 (pl) 2025-03-03
AU2023202710A1 (en) 2023-05-18
KR20170086656A (ko) 2017-07-26
CO2017005572A2 (es) 2017-09-20
SG11201704267VA (en) 2017-06-29
EA201791222A1 (ru) 2017-09-29
EP4494636A3 (en) 2025-04-30
MX2017007203A (es) 2017-08-28
MD3226841T2 (ro) 2025-06-30
JP6937692B2 (ja) 2021-09-22
TW202031248A (zh) 2020-09-01
EP3226841C0 (en) 2024-10-09
TWI702966B (zh) 2020-09-01
AU2015358490A1 (en) 2017-06-08
MX2021013965A (es) 2022-01-04
TW201630592A (zh) 2016-09-01

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