BR112016014010A2 - métodos para detectar anticorpos contra vírus da febre suína clássica tipo selvagem (csfv), para diferenciação entre animais infectados com csfv tipo selvagem e animais que foram vacinados contra csfv e para controlar uma infecção com csfv tipo selvagem, kit de teste de diagnóstico, e, uso de um carreador - Google Patents

métodos para detectar anticorpos contra vírus da febre suína clássica tipo selvagem (csfv), para diferenciação entre animais infectados com csfv tipo selvagem e animais que foram vacinados contra csfv e para controlar uma infecção com csfv tipo selvagem, kit de teste de diagnóstico, e, uso de um carreador

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Publication number
BR112016014010A2
BR112016014010A2 BR112016014010A BR112016014010A BR112016014010A2 BR 112016014010 A2 BR112016014010 A2 BR 112016014010A2 BR 112016014010 A BR112016014010 A BR 112016014010A BR 112016014010 A BR112016014010 A BR 112016014010A BR 112016014010 A2 BR112016014010 A2 BR 112016014010A2
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Brazil
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csfv
wild
type
animals
test kit
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BR112016014010A
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English (en)
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BR112016014010B1 (pt
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Peter Bruderer Urs
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Intervet Int Bv
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Publication of BR112016014010A2 publication Critical patent/BR112016014010A2/pt
Publication of BR112016014010B1 publication Critical patent/BR112016014010B1/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Microbiology (AREA)
  • Biotechnology (AREA)
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  • Physics & Mathematics (AREA)
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  • Cell Biology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

a presente invenção se refere ao campo de diagnóstico veterinário, especificamente a um teste para a detecção de anticorpos contra csfv. em particular, a invenção se refere a um método para detectar anticorpos contra csfv tipo selvagem em uma amostra de teste, distinguido pelo fato de que o método compreende coincubação com um carreador compreendendo um epítopo tavspttlr mutado de proteína e2 do csfv. adicionalmente, a invenção se refere a um kit de teste de diagnóstico e ao uso do método de acordo com a invenção. além do mais, a invenção se refere a um método para diferenciação entre animais infectados com csfv tipo selvagem e animais que foram vacinados contra csfv com uma vacina contra csfv (marcador), e a um método para controlar uma infecção com csfv tipo selvagem em uma população de animais suínos, pelo uso combinado de uma vacina contra csfv (marcador) e o kit de teste de diagnóstico da invenção.
BR112016014010-9A 2013-12-19 2014-12-18 Método para detectar anticorpos contra vírus da febre suína clássica tipo selvagem (csfv) em uma amostra de teste e kit de teste de diagnóstico BR112016014010B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13198615.0 2013-12-19
EP13198615 2013-12-19
PCT/EP2014/078373 WO2015091736A1 (en) 2013-12-19 2014-12-18 Improved diagnostic test for csfv antibodies

Publications (2)

Publication Number Publication Date
BR112016014010A2 true BR112016014010A2 (pt) 2018-01-09
BR112016014010B1 BR112016014010B1 (pt) 2022-08-30

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BR112016014010-9A BR112016014010B1 (pt) 2013-12-19 2014-12-18 Método para detectar anticorpos contra vírus da febre suína clássica tipo selvagem (csfv) em uma amostra de teste e kit de teste de diagnóstico

Country Status (11)

Country Link
US (1) US9739778B2 (pt)
EP (1) EP3084441B1 (pt)
JP (1) JP6383422B2 (pt)
KR (1) KR101848194B1 (pt)
CN (1) CN105829892B (pt)
BR (1) BR112016014010B1 (pt)
ES (1) ES2668459T3 (pt)
HU (1) HUE038721T2 (pt)
RU (1) RU2689143C1 (pt)
TW (1) TWI611188B (pt)
WO (1) WO2015091736A1 (pt)

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JP6383422B2 (ja) * 2013-12-19 2018-08-29 インターベット インターナショナル ベー． フェー． Ｃｓｆｖ抗体に関する改善された診断試験
CN106383226A (zh) * 2016-08-19 2017-02-08 金宇保灵生物药品有限公司 猪血清中猪瘟中和抗体效价的定量检测方法及检测试剂盒
CN107064501B (zh) * 2017-05-02 2019-04-16 中国农业科学院兰州兽医研究所 一种定量检测猪瘟病毒IgG抗体竞争ELISA试剂盒及其检测方法
CN107828745B (zh) * 2017-11-15 2021-01-05 中国兽医药品监察所 猪瘟兔化弱毒表位突变株及其应用
WO2020211801A1 (en) * 2019-04-18 2020-10-22 Boehringer Ingelheim Vetmedica (China) Co., Ltd. Recombinant classical swine fever virus
CN111044494B (zh) * 2019-11-26 2022-08-23 安徽云燕食品科技有限公司 一种猪瘟的快速检测方法
CN112375126B (zh) * 2020-11-04 2022-07-29 天康生物制药有限公司 标记猪瘟病毒e2蛋白重组杆状病毒灭活疫苗
CN114236128B (zh) * 2021-11-30 2022-07-29 中国农业科学院兰州兽医研究所 一种检测猪急性腹泻综合征冠状病毒n蛋白抗体的阻断elisa试剂盒
CN116068175B (zh) * 2022-09-07 2024-06-07 中国农业科学院兰州兽医研究所 一种基于e2蛋白二聚体的猪瘟病毒管式化学发光抗体检测试剂盒及其应用
CN116953234B (zh) * 2023-08-25 2024-05-17 中国农业科学院兰州兽医研究所 一种猪博卡病毒g3型的多肽-elisa抗体检测试剂盒

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NZ287563A (en) * 1994-06-17 1998-08-26 Inst Veehouderij Diergezondh Dna sequence of classical swine fever virus (csfv), vaccine and diagnostic test
US7763460B2 (en) * 2005-06-24 2010-07-27 Focus Diagnostics, Inc. Methods and compositions for detecting herpes simplex virus type 2
US8846055B2 (en) 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
CN101144818B (zh) * 2007-10-19 2011-04-27 清华大学 检测猪瘟病毒特异性抗体的方法及其酶联免疫试剂盒
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EP2202298A1 (en) * 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV
BR112014004261B8 (pt) * 2011-08-24 2022-11-08 Zoetis Llc Diagnósticos de vacina melhorada
JP6383422B2 (ja) * 2013-12-19 2018-08-29 インターベット インターナショナル ベー． フェー． Ｃｓｆｖ抗体に関する改善された診断試験

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Publication number Publication date
TWI611188B (zh) 2018-01-11
JP6383422B2 (ja) 2018-08-29
TW201530141A (zh) 2015-08-01
CN105829892A (zh) 2016-08-03
HUE038721T2 (hu) 2018-11-28
BR112016014010B1 (pt) 2022-08-30
ES2668459T3 (es) 2018-05-18
KR101848194B1 (ko) 2018-04-11
US20160313330A1 (en) 2016-10-27
WO2015091736A1 (en) 2015-06-25
RU2016129161A (ru) 2018-01-24
EP3084441A1 (en) 2016-10-26
EP3084441B1 (en) 2018-03-28
JP2017503165A (ja) 2017-01-26
US9739778B2 (en) 2017-08-22
CN105829892B (zh) 2018-06-12
RU2689143C1 (ru) 2019-05-24
KR20160097219A (ko) 2016-08-17

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