BR112015004085A2 - método para cultivar uma cepa de rotavírus (rv); método para gerar uma rv3 atenuada em células vero; rv3 adaptada à vero isolada; composição de rv morto ou vivo atenuado; método para vacinar um indivíduo humano contra infecção por rv; método para tratar um indivíduo humano com uma infecção por rv ou em risco de desenvolver uma infecção ou reinfecção por rv; uso da rv3 de vero; anticorpo isolado; e método para detectar ou monitorar a rv3 de vero - Google Patents

método para cultivar uma cepa de rotavírus (rv); método para gerar uma rv3 atenuada em células vero; rv3 adaptada à vero isolada; composição de rv morto ou vivo atenuado; método para vacinar um indivíduo humano contra infecção por rv; método para tratar um indivíduo humano com uma infecção por rv ou em risco de desenvolver uma infecção ou reinfecção por rv; uso da rv3 de vero; anticorpo isolado; e método para detectar ou monitorar a rv3 de vero

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Publication number
BR112015004085A2
BR112015004085A2 BR112015004085A BR112015004085A BR112015004085A2 BR 112015004085 A2 BR112015004085 A2 BR 112015004085A2 BR 112015004085 A BR112015004085 A BR 112015004085A BR 112015004085 A BR112015004085 A BR 112015004085A BR 112015004085 A2 BR112015004085 A2 BR 112015004085A2
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Brazil
Prior art keywords
summer
infection
attenuated
human individual
isolated
Prior art date
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BR112015004085A
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English (en)
Inventor
kirkwood Carl
Laurence Barnes Graeme
Frances Bishop Ruth
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Murdoch Childrens Res Inst
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Publication date
Priority claimed from AU2012903702A external-priority patent/AU2012903702A0/en
Application filed by Murdoch Childrens Res Inst filed Critical Murdoch Childrens Res Inst
Publication of BR112015004085A2 publication Critical patent/BR112015004085A2/pt

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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
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Abstract

resumo método para cultivar uma cepa de rotavírus (rv); método para gerar uma rv3 atenuada em células vero; rv3 adaptada à vero isolada; composição de rv morto ou vivo atenuado; método para vacinar um indivíduo humano contra infecção por rv; método para tratar um indivíduo humano com uma infecção por rv ou em risco de desenvolver uma infecção ou reinfecção por rv; uso da rv3 de vero; anticorpo isolado; e método para detectar ou monitorar a rv3 de vero a presente revelação refere-se, de modo geral, ao campo de vacinas virais. particularmente, a presente revelação fornece uma cepa de rotavírus humana modificada e um método de cultura para produzir um vírus de titulação alta, uma vacina contra o rotavírus, protocolos de vacinação e ensaios de diagnóstico e prognóstico.
BR112015004085A 2012-08-27 2013-08-26 método para cultivar uma cepa de rotavírus (rv); método para gerar uma rv3 atenuada em células vero; rv3 adaptada à vero isolada; composição de rv morto ou vivo atenuado; método para vacinar um indivíduo humano contra infecção por rv; método para tratar um indivíduo humano com uma infecção por rv ou em risco de desenvolver uma infecção ou reinfecção por rv; uso da rv3 de vero; anticorpo isolado; e método para detectar ou monitorar a rv3 de vero BR112015004085A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2012903702A AU2012903702A0 (en) 2012-08-27 Modified human rotaviruses and uses therefor
PCT/AU2013/000945 WO2014032082A1 (en) 2012-08-27 2013-08-26 Modified human rotaviruses and uses therefor

Publications (1)

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BR112015004085A2 true BR112015004085A2 (pt) 2017-08-08

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BR112015004085A BR112015004085A2 (pt) 2012-08-27 2013-08-26 método para cultivar uma cepa de rotavírus (rv); método para gerar uma rv3 atenuada em células vero; rv3 adaptada à vero isolada; composição de rv morto ou vivo atenuado; método para vacinar um indivíduo humano contra infecção por rv; método para tratar um indivíduo humano com uma infecção por rv ou em risco de desenvolver uma infecção ou reinfecção por rv; uso da rv3 de vero; anticorpo isolado; e método para detectar ou monitorar a rv3 de vero

Country Status (11)

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US (2) US9969985B2 (pt)
EP (1) EP2888355B1 (pt)
KR (1) KR102182186B1 (pt)
CN (1) CN104812892B (pt)
AU (1) AU2013308377B2 (pt)
BR (1) BR112015004085A2 (pt)
CU (1) CU24328B1 (pt)
IN (1) IN2015DN01342A (pt)
MX (1) MX370502B (pt)
NZ (1) NZ631348A (pt)
WO (1) WO2014032082A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201900250D0 (en) 2019-01-08 2019-02-27 Ge Healthcare Bio Sciences Ab Method for virus propagation
CN117257928A (zh) * 2023-09-22 2023-12-22 成都迈科康生物科技有限公司 一种冻干口服轮状减毒活疫苗及其制备方法和应用
CN117947096B (zh) * 2024-01-16 2024-08-30 伊诺维康(北京)生物科技有限公司 一种羊轮状病毒重组质粒、反向遗传病毒学拯救系统及其构建方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4579945A (en) 1982-04-29 1986-04-01 Ribi Immunochem Research, Inc. Purification of trehalose dimycolates
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
US6056957A (en) 1994-08-04 2000-05-02 Schering Corporation Humanized monoclonal antibodies against human interleukin-5
GB9919468D0 (en) * 1999-08-17 1999-10-20 Smithkline Beecham Biolog Vaccine
HU228975B1 (en) 1999-08-17 2013-07-29 Smithkline Beecham Biolog Vaccine
AU2007251122B2 (en) * 2006-05-12 2013-01-10 Bharat Biotech International Limited A composition useful as a vaccine
ES2723776T3 (es) * 2009-05-12 2019-09-02 The Government Of The Us Secretary Department Of Health And Human Services Nuevas cepas de rotavirus humano y vacunas

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Publication number Publication date
EP2888355B1 (en) 2020-06-17
KR20150044954A (ko) 2015-04-27
KR102182186B1 (ko) 2020-11-25
MX370502B (es) 2019-12-16
CU20150019A7 (es) 2015-09-29
AU2013308377A1 (en) 2015-02-26
CN104812892B (zh) 2018-07-17
EP2888355A4 (en) 2016-08-10
WO2014032082A8 (en) 2015-04-16
EP2888355A1 (en) 2015-07-01
CN104812892A (zh) 2015-07-29
CU24328B1 (es) 2018-03-13
AU2013308377B2 (en) 2019-06-06
NZ631348A (en) 2017-02-24
US20150337268A1 (en) 2015-11-26
US9969985B2 (en) 2018-05-15
US20180346884A1 (en) 2018-12-06
MX2015002495A (es) 2016-06-30
IN2015DN01342A (pt) 2015-07-03
WO2014032082A1 (en) 2014-03-06

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