BR112015030946A2 - composição compreendendo uma célula ß pancreática não-nativa, método de diferenciação de células progenitoras em células ß pancreáticas in vitro e uso de uma célula ß pancreática não-nativa - Google Patents

composição compreendendo uma célula ß pancreática não-nativa, método de diferenciação de células progenitoras em células ß pancreáticas in vitro e uso de uma célula ß pancreática não-nativa

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Publication number
BR112015030946A2
BR112015030946A2 BR112015030946A BR112015030946A BR112015030946A2 BR 112015030946 A2 BR112015030946 A2 BR 112015030946A2 BR 112015030946 A BR112015030946 A BR 112015030946A BR 112015030946 A BR112015030946 A BR 112015030946A BR 112015030946 A2 BR112015030946 A2 BR 112015030946A2
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Brazil
Prior art keywords
pancreatic
cell
cells
native
vitro
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BR112015030946A
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English (en)
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BR112015030946A8 (pt
Inventor
Quinn P Peterson
Felicia J Pagliuca
Douglas A Melton
Jeffrey R Millman
Michael Saris Segel
Mads Gurtler
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Harvard College
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Application filed by Harvard College filed Critical Harvard College
Publication of BR112015030946A2 publication Critical patent/BR112015030946A2/pt
Publication of BR112015030946A8 publication Critical patent/BR112015030946A8/pt

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
BR112015030946A 2013-06-11 2014-06-11 composição compreendendo uma célula ß pancreática não-nativa, método de diferenciação de células progenitoras em células ß pancreáticas in vitro e uso de uma célula ß pancreática não-nativa BR112015030946A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361833898P 2013-06-11 2013-06-11
US201461972212P 2014-03-28 2014-03-28
PCT/US2014/041992 WO2014201167A1 (en) 2013-06-11 2014-06-11 SC-β CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME

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BR112015030946A2 true BR112015030946A2 (pt) 2017-07-25
BR112015030946A8 BR112015030946A8 (pt) 2020-01-28

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BR112015030972A BR112015030972A8 (pt) 2013-06-11 2014-06-11 células sc-beta e composições e métodos para geração das mesmas
BR112015030946A BR112015030946A8 (pt) 2013-06-11 2014-06-11 composição compreendendo uma célula ß pancreática não-nativa, método de diferenciação de células progenitoras em células ß pancreáticas in vitro e uso de uma célula ß pancreática não-nativa

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BR112015030972A BR112015030972A8 (pt) 2013-06-11 2014-06-11 células sc-beta e composições e métodos para geração das mesmas

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US (14) US20170029778A1 (pt)
EP (3) EP3008170A4 (pt)
JP (7) JP6677634B2 (pt)
KR (12) KR102390167B1 (pt)
CN (4) CN106414718A (pt)
AU (6) AU2014284677B2 (pt)
BR (2) BR112015030972A8 (pt)
CA (2) CA2915088A1 (pt)
DE (2) DE202014011287U1 (pt)
DK (1) DK3008168T3 (pt)
GB (3) GB2557508B (pt)
HK (1) HK1257187B (pt)
MX (2) MX2015017103A (pt)
PH (1) PH12015502767A1 (pt)
RU (2) RU2016100219A (pt)
SG (3) SG10201710218RA (pt)
WO (2) WO2015002724A2 (pt)

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