BR112015027373A2 - Processo de expressão - Google Patents
Processo de expressãoInfo
- Publication number
- BR112015027373A2 BR112015027373A2 BR112015027373A BR112015027373A BR112015027373A2 BR 112015027373 A2 BR112015027373 A2 BR 112015027373A2 BR 112015027373 A BR112015027373 A BR 112015027373A BR 112015027373 A BR112015027373 A BR 112015027373A BR 112015027373 A2 BR112015027373 A2 BR 112015027373A2
- Authority
- BR
- Brazil
- Prior art keywords
- target polypeptide
- expression
- expression vector
- expressing
- expression process
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 239000013604 expression vector Substances 0.000 abstract 2
- 102000016359 Fibronectins Human genes 0.000 abstract 1
- 108010067306 Fibronectins Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201308017A GB201308017D0 (en) | 2013-05-03 | 2013-05-03 | Expression process |
| GB201320339A GB201320339D0 (en) | 2013-11-18 | 2013-11-18 | Expression Process |
| PCT/GB2014/000165 WO2014177826A1 (en) | 2013-05-03 | 2014-04-29 | Expression process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015027373A2 true BR112015027373A2 (pt) | 2017-08-29 |
Family
ID=50639794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015027373A BR112015027373A2 (pt) | 2013-05-03 | 2014-04-29 | Processo de expressão |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9873891B2 (enExample) |
| EP (1) | EP2992104B1 (enExample) |
| JP (1) | JP6545153B2 (enExample) |
| KR (1) | KR102180660B1 (enExample) |
| CN (2) | CN105392889A (enExample) |
| BR (1) | BR112015027373A2 (enExample) |
| CA (1) | CA2910877C (enExample) |
| DK (1) | DK2992104T3 (enExample) |
| ES (1) | ES2732907T3 (enExample) |
| RU (1) | RU2731717C2 (enExample) |
| SG (1) | SG11201508447TA (enExample) |
| WO (1) | WO2014177826A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3323826A1 (en) * | 2016-11-21 | 2018-05-23 | Danmarks Tekniske Universitet | Native chinese hamster ovary cell secretion signal peptides for production of recombinant polypeptides |
| EP3725877A4 (en) | 2017-12-11 | 2021-02-17 | FUJIFILM Corporation | ANIMAL CELLS AS WELL AS A METHOD FOR MANUFACTURING THE SAME, AND A METHOD FOR MANUFACTURING TARGET PROTEIN |
| JP7123168B2 (ja) | 2018-12-11 | 2022-08-22 | 富士フイルム株式会社 | 動物細胞、動物細胞の製造方法および目的タンパク質の製造方法 |
| CN109837277A (zh) * | 2019-03-01 | 2019-06-04 | 深圳生生凡非基因技术有限公司 | 一种cpgk嵌合型启动子、腺相关病毒载体及其应用 |
| EP4067474A4 (en) | 2019-11-29 | 2023-01-18 | FUJIFILM Corporation | CELL CULTURE METHOD, ANTIBODY PRODUCTION METHOD, ORGANIC ACID AND ANTIBODY REMOVAL METHOD |
| WO2022149607A1 (ja) | 2021-01-07 | 2022-07-14 | 富士フイルム株式会社 | 細胞の選択方法、装置、及び装置システム |
| JPWO2022196710A1 (enExample) | 2021-03-17 | 2022-09-22 | ||
| CN112980852B (zh) * | 2021-05-18 | 2021-08-13 | 北京华芢生物技术有限公司 | 新型冠状病毒b.1.351南非突变株rbd的基因及其应用 |
| WO2022249089A1 (en) | 2021-05-27 | 2022-12-01 | Janssen Biotech, Inc. | Compositions and methods for the treatment of prostate cancer |
| WO2023054556A1 (ja) | 2021-09-30 | 2023-04-06 | 富士フイルム株式会社 | 細胞培養方法、及び有用物質の製造方法 |
| EP4450609A1 (en) | 2021-12-15 | 2024-10-23 | FUJIFILM Corporation | Method for producing product, and cell culture apparatus |
| JPWO2023190300A1 (enExample) | 2022-03-28 | 2023-10-05 | ||
| WO2023190829A1 (ja) | 2022-03-31 | 2023-10-05 | 富士フイルム株式会社 | 生産物の製造方法、及び生産物 |
| JPWO2023238949A1 (enExample) | 2022-06-10 | 2023-12-14 | ||
| EP4596704A1 (en) | 2022-09-29 | 2025-08-06 | FUJIFILM Corporation | Method for producing product |
| WO2024248120A1 (ja) | 2023-05-31 | 2024-12-05 | 富士フイルム株式会社 | 生産物の生産方法 |
| WO2024248118A1 (ja) | 2023-05-31 | 2024-12-05 | 富士フイルム株式会社 | 細胞培養方法および生産物の製造方法 |
| CN121175432A (zh) | 2023-05-31 | 2025-12-19 | 富士胶片株式会社 | 生产物的生产方法 |
| WO2025244971A1 (en) | 2024-05-20 | 2025-11-27 | Janssen Biotech, Inc. | Compositions and methods for the treatment of prostate cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003093295A2 (en) * | 2002-04-30 | 2003-11-13 | University Of North Carolina At Chapel Hill | Secretion signal vectors |
| US7186699B2 (en) * | 2003-06-03 | 2007-03-06 | Cell Genesys, Inc. | Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes |
| US8029783B2 (en) * | 2005-02-02 | 2011-10-04 | Genentech, Inc. | DR5 antibodies and articles of manufacture containing same |
| EP1739179A1 (en) * | 2005-06-30 | 2007-01-03 | Octapharma AG | Serum-free stable transfection and production of recombinant human proteins in human cell lines |
| GB0602173D0 (en) * | 2006-02-03 | 2006-03-15 | Avecia Ltd | Expression system |
| MX2009007139A (es) * | 2006-12-28 | 2009-10-08 | Centocor Ortho Biotech Inc | Metodos y vectores para generar inmunoglobulinas no sialiladas. |
| KR101618767B1 (ko) * | 2008-09-02 | 2016-05-09 | 한국생명공학연구원 | 외래단백질을 고효율로 생산하는 리더서열 |
| CN102272160A (zh) * | 2008-12-31 | 2011-12-07 | 印度血清及疫苗有限公司 | 抗rhd单克隆抗体 |
| TW201613969A (en) | 2009-03-05 | 2016-04-16 | Abbvie Inc | IL-17 binding proteins |
| GB0905331D0 (en) * | 2009-03-27 | 2009-05-13 | Avecia Biolog Ltd | Expression process |
| KR101420274B1 (ko) * | 2011-06-13 | 2014-07-21 | 주식회사 종근당 | Ｃｓｐ－ｂ ５＇ｓａｒ 인자를 포함하는 동물세포 발현 벡터 및 이를 이용한 재조합 단백질의 제조방법 |
-
2014
- 2014-04-29 SG SG11201508447TA patent/SG11201508447TA/en unknown
- 2014-04-29 WO PCT/GB2014/000165 patent/WO2014177826A1/en not_active Ceased
- 2014-04-29 ES ES14721474T patent/ES2732907T3/es active Active
- 2014-04-29 CN CN201480024993.4A patent/CN105392889A/zh active Pending
- 2014-04-29 JP JP2016511126A patent/JP6545153B2/ja active Active
- 2014-04-29 CA CA2910877A patent/CA2910877C/en active Active
- 2014-04-29 EP EP14721474.6A patent/EP2992104B1/en active Active
- 2014-04-29 BR BR112015027373A patent/BR112015027373A2/pt not_active Application Discontinuation
- 2014-04-29 US US14/787,669 patent/US9873891B2/en active Active
- 2014-04-29 KR KR1020157032562A patent/KR102180660B1/ko active Active
- 2014-04-29 RU RU2015151626A patent/RU2731717C2/ru active
- 2014-04-29 CN CN202111508425.XA patent/CN114395584B/zh active Active
- 2014-04-29 DK DK14721474.6T patent/DK2992104T3/da active
-
2017
- 2017-12-12 US US15/838,868 patent/US11306323B2/en active Active
-
2022
- 2022-03-15 US US17/694,760 patent/US20220213500A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014177826A1 (en) | 2014-11-06 |
| CA2910877C (en) | 2021-08-03 |
| US11306323B2 (en) | 2022-04-19 |
| RU2015151626A (ru) | 2017-06-08 |
| CA2910877A1 (en) | 2014-11-06 |
| CN114395584B (zh) | 2025-01-28 |
| JP6545153B2 (ja) | 2019-07-17 |
| EP2992104A1 (en) | 2016-03-09 |
| JP2016517691A (ja) | 2016-06-20 |
| EP2992104B1 (en) | 2019-04-17 |
| SG11201508447TA (en) | 2015-11-27 |
| US9873891B2 (en) | 2018-01-23 |
| KR102180660B1 (ko) | 2020-11-19 |
| US20180127777A1 (en) | 2018-05-10 |
| US20220213500A1 (en) | 2022-07-07 |
| US20160076051A1 (en) | 2016-03-17 |
| RU2015151626A3 (enExample) | 2018-03-20 |
| RU2731717C2 (ru) | 2020-09-08 |
| CN105392889A (zh) | 2016-03-09 |
| KR20160003705A (ko) | 2016-01-11 |
| DK2992104T3 (da) | 2019-07-15 |
| CN114395584A (zh) | 2022-04-26 |
| ES2732907T3 (es) | 2019-11-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015027373A2 (pt) | Processo de expressão | |
| PE20171142A1 (es) | Vectores para expresion de antigenos asociados a prostata | |
| MX371025B (es) | Células eucariotas novedosas y métodos para la expresión recombinante de un producto de interés. | |
| GB2502937A (en) | Running a plurality of instances of an application | |
| IN2015DN02771A (enExample) | ||
| CL2012003014A1 (es) | Acido nucleico aislado que codifica un receptor pyr/pyl mutado; polipeptido codificado por dicho acido nucleico; casette y vector de expresión que comprenden el polinucleotido descrito anteriormente y metodo para aumentar la tolerancia al estrés en una planta. | |
| NZ717647A (en) | Structure based predictive modeling | |
| CL2016000232A1 (es) | Estabilización de polipéptidos que contienen fragmentos cristalizables | |
| BR112019008484A2 (pt) | circuito, estação base, método realizado por um processador, e, mídia de gravação. | |
| AR089571A1 (es) | Metodos y aparatos de codificacion de datos de video | |
| MX2015012875A (es) | Composiciones de cultivo celular con antioxidantes y metodos para la produccion de polipeptidos. | |
| BR112016008830A2 (pt) | Método para produzir uma substância alvo | |
| BR112013032037A2 (pt) | método para processar uma solicitação de pesquisa, meio legível por computador, programa legível por computador e sistema para processar uma solicitação de pesquisa | |
| BR112015030435A8 (pt) | computador, artigo de fabricação e processo para proporcionar temporizadores por processador virtuais para sistemas de processador múltiplo | |
| BR112016024895A2 (pt) | fator secretório de proteína com alta eficácia secretória e um vetor de expressão compreendendo o mesmo | |
| AR087103A1 (es) | Tecnologia de simulacion integrada | |
| MX2016006816A (es) | Promotores sinteticos para celulas de ovario de hamster chino (cho), metodos de produccion de promotores sinteticos usando modulos de sitio de union del factor de transcripcion. | |
| GB201305554D0 (en) | Implementing remapping command with indirection update for indirected storage | |
| BR112016012229A2 (pt) | métodos de produção de polipeptídeos | |
| MX373329B (es) | Células eucariotas novedosas y métodos para la expresión recombinante de un producto de interés. | |
| BR112018009732A8 (pt) | ?polinucleotídeo, vetor de vírus adeno-associado, partícula de vírus adeno-associado, célula hospedeira, métodos para produzir uma partícula de vírus adeno-associado, para tratar hemofilia a, para transduzir uma célula hospedeira, e, uso de uma partícula de vírus adeno-associado? | |
| EA202190244A3 (ru) | Сверхэкспрессия регуляторов пути n-гликозилирования для модуляции гликозилирования рекомбинантных белков | |
| AR097805A1 (es) | Células de cambio de temperatura para la expresión de alto rendimiento de polipéptidos en levadura y otros transformados | |
| BR112018005464A2 (pt) | expressão de proteínas contendo fc | |
| MX2016016565A (es) | Polipeptidos de fusion relacionados con omega-hidroxilasa con propiedades mejoradas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |