BR112015015045A8 - partículas derivadas de vírus não replicante e respectivos usos. - Google Patents
partículas derivadas de vírus não replicante e respectivos usos. Download PDFInfo
- Publication number
- BR112015015045A8 BR112015015045A8 BR112015015045A BR112015015045A BR112015015045A8 BR 112015015045 A8 BR112015015045 A8 BR 112015015045A8 BR 112015015045 A BR112015015045 A BR 112015015045A BR 112015015045 A BR112015015045 A BR 112015015045A BR 112015015045 A8 BR112015015045 A8 BR 112015015045A8
- Authority
- BR
- Brazil
- Prior art keywords
- replicating
- derived
- rhabdovirus
- cells
- particles derived
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 5
- 230000003362 replicative effect Effects 0.000 title abstract 5
- 241000700605 Viruses Species 0.000 title abstract 2
- 230000010415 tropism Effects 0.000 abstract 2
- 230000003044 adaptive effect Effects 0.000 abstract 1
- 230000001461 cytolytic effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/766—Rhabdovirus, e.g. vesicular stomatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/06—Inactivation or attenuation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20061—Methods of inactivation or attenuation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20261—Methods of inactivation or attenuation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20261—Methods of inactivation or attenuation
- C12N2760/20263—Methods of inactivation or attenuation by chemical treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261740856P | 2012-12-21 | 2012-12-21 | |
| US201361835310P | 2013-06-14 | 2013-06-14 | |
| PCT/CA2013/051009 WO2014094182A1 (en) | 2012-12-21 | 2013-12-20 | Non-replicating virus-derived particles and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015015045A8 true BR112015015045A8 (pt) | 2018-01-23 |
Family
ID=50977496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015015045A BR112015015045A8 (pt) | 2012-12-21 | 2013-12-20 | partículas derivadas de vírus não replicante e respectivos usos. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11110138B2 (https=) |
| EP (1) | EP2935569B1 (https=) |
| JP (2) | JP6612619B2 (https=) |
| KR (1) | KR102167497B1 (https=) |
| CN (1) | CN105121636A (https=) |
| AU (1) | AU2013362761B2 (https=) |
| BR (1) | BR112015015045A8 (https=) |
| CA (1) | CA2896162C (https=) |
| CL (1) | CL2015001738A1 (https=) |
| ES (1) | ES2745599T3 (https=) |
| IL (1) | IL239486B (https=) |
| MX (1) | MX376266B (https=) |
| MY (1) | MY174912A (https=) |
| PH (1) | PH12015501442A1 (https=) |
| RU (1) | RU2705556C2 (https=) |
| SG (2) | SG11201504843UA (https=) |
| WO (1) | WO2014094182A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014094182A1 (en) * | 2012-12-21 | 2014-06-26 | Ottawa Hospital Research Institute | Non-replicating virus-derived particles and uses thereof |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| CN109985244A (zh) * | 2017-12-29 | 2019-07-09 | 广州威溶特医药科技有限公司 | E3连接酶抑制剂和溶瘤病毒在制备抗肿瘤药物的应用 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CN109432098B (zh) * | 2018-11-20 | 2021-04-13 | 天津大学 | 化合物ps-341在制备小rna病毒科肠道病毒属病毒抑制剂的应用 |
| EP3708176A1 (en) * | 2019-03-15 | 2020-09-16 | Centre National De La Recherche Scientifique -Cnrs- | Mutant vsv ectodomain polypeptide and uses thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5106619A (en) | 1983-12-20 | 1992-04-21 | Diamond Scientific Co. | Preparation of inactivated viral vaccines |
| HK1052950B (en) * | 2000-06-26 | 2005-06-24 | Wellstat Biologics Corporation | Purging of cells using viruses |
| JP2005537802A (ja) | 2002-09-09 | 2005-12-15 | ユニバーシティ・オブ・テネシー・リサーチ・ファウンデーション | ラブドウイルスの組み換え型変異体及びその使用方法 |
| JP4708027B2 (ja) * | 2002-10-01 | 2011-06-22 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 抗癌組成物および抗感染疾患組成物ならびにこれらを使用する方法 |
| AU2003279770A1 (en) | 2002-10-01 | 2004-04-23 | Novartis Vaccines And Diagnostics, Inc. | Anti-cancer and anti-infectious disease compositions and methods for using same |
| CN100579579C (zh) * | 2002-10-01 | 2010-01-13 | 诺华疫苗和诊断公司 | 抗癌及抗感染性疾病组合物及其使用方法 |
| DE602004018284D1 (de) | 2003-03-27 | 2009-01-22 | Ottawa Health Research Inst | Mutante vesicular stomatitis viren und deren verwendungen |
| US7807176B2 (en) * | 2004-03-19 | 2010-10-05 | Genomidea, Inc. | Polypeptide promoting vascular endothelial cell growth |
| US8703467B2 (en) * | 2004-05-27 | 2014-04-22 | Baxter International Inc. | Inactivation of a pathogen in a sample by a treatment with formalin and UV light |
| CA2663034C (en) | 2006-09-15 | 2016-05-03 | Ottawa Health Research Institute | Oncolytic rhabdovirus |
| JP5547640B2 (ja) * | 2008-09-16 | 2014-07-16 | ジェノミディア株式会社 | 前立腺癌の治療・予防剤 |
| CA2836117C (en) * | 2009-12-10 | 2017-08-15 | Ottawa Hospital Research Institute | Oncolytic rhabdovirus |
| US20130302368A1 (en) * | 2011-01-27 | 2013-11-14 | Boro Dropulic | Advanced Prime and Boost Vaccine |
| CN103403594B (zh) * | 2011-02-02 | 2016-11-23 | 康宁光缆系统有限责任公司 | 适用于为设备机架中的光学底板建立光学连接的稠密的光阀遮蔽的光纤连接器及总成 |
| WO2012122649A1 (en) * | 2011-03-15 | 2012-09-20 | Ottawa Hospital Research Institute | Recombinant orf virus |
| US9623096B2 (en) * | 2011-11-09 | 2017-04-18 | Celverum Inc. | Virally infected hematopoietic cells and uses thereof |
| WO2014094182A1 (en) * | 2012-12-21 | 2014-06-26 | Ottawa Hospital Research Institute | Non-replicating virus-derived particles and uses thereof |
-
2013
- 2013-12-20 WO PCT/CA2013/051009 patent/WO2014094182A1/en not_active Ceased
- 2013-12-20 BR BR112015015045A patent/BR112015015045A8/pt not_active Application Discontinuation
- 2013-12-20 EP EP13865170.8A patent/EP2935569B1/en active Active
- 2013-12-20 ES ES13865170T patent/ES2745599T3/es active Active
- 2013-12-20 CN CN201380071341.1A patent/CN105121636A/zh active Pending
- 2013-12-20 SG SG11201504843UA patent/SG11201504843UA/en unknown
- 2013-12-20 MX MX2015008155A patent/MX376266B/es active IP Right Grant
- 2013-12-20 US US14/654,259 patent/US11110138B2/en not_active Expired - Fee Related
- 2013-12-20 AU AU2013362761A patent/AU2013362761B2/en not_active Ceased
- 2013-12-20 KR KR1020157019923A patent/KR102167497B1/ko not_active Expired - Fee Related
- 2013-12-20 JP JP2015548131A patent/JP6612619B2/ja not_active Expired - Fee Related
- 2013-12-20 SG SG10201704903YA patent/SG10201704903YA/en unknown
- 2013-12-20 RU RU2015128766A patent/RU2705556C2/ru active
- 2013-12-20 MY MYPI2015702052A patent/MY174912A/en unknown
- 2013-12-20 CA CA2896162A patent/CA2896162C/en not_active Expired - Fee Related
-
2015
- 2015-06-17 IL IL239486A patent/IL239486B/en active IP Right Grant
- 2015-06-18 CL CL2015001738A patent/CL2015001738A1/es unknown
- 2015-06-19 PH PH12015501442A patent/PH12015501442A1/en unknown
-
2019
- 2019-09-11 JP JP2019165067A patent/JP2020014467A/ja active Pending
-
2021
- 2021-07-21 US US17/382,146 patent/US20210346441A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN105121636A (zh) | 2015-12-02 |
| US20210346441A1 (en) | 2021-11-11 |
| AU2013362761A1 (en) | 2015-07-16 |
| CA2896162C (en) | 2021-10-12 |
| JP2016501538A (ja) | 2016-01-21 |
| SG10201704903YA (en) | 2017-07-28 |
| US11110138B2 (en) | 2021-09-07 |
| CL2015001738A1 (es) | 2015-12-18 |
| IL239486B (en) | 2019-08-29 |
| NZ709439A (en) | 2020-09-25 |
| MX376266B (es) | 2025-03-07 |
| MY174912A (en) | 2020-05-21 |
| RU2015128766A (ru) | 2017-01-26 |
| EP2935569B1 (en) | 2019-05-01 |
| JP6612619B2 (ja) | 2019-11-27 |
| CA2896162A1 (en) | 2014-06-26 |
| JP2020014467A (ja) | 2020-01-30 |
| RU2705556C2 (ru) | 2019-11-07 |
| MX2015008155A (es) | 2016-02-05 |
| KR102167497B1 (ko) | 2020-10-20 |
| EP2935569A4 (en) | 2016-08-03 |
| PH12015501442A1 (en) | 2015-09-14 |
| EP2935569A1 (en) | 2015-10-28 |
| AU2013362761B2 (en) | 2019-08-01 |
| WO2014094182A1 (en) | 2014-06-26 |
| US20150320810A1 (en) | 2015-11-12 |
| IL239486A0 (en) | 2015-07-30 |
| SG11201504843UA (en) | 2015-07-30 |
| HK1210624A1 (en) | 2016-04-29 |
| ES2745599T3 (es) | 2020-03-02 |
| KR20150112957A (ko) | 2015-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: CELVERUM INC. (CA) |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |