KR102167497B1 - 비복제성 바이러스유래 입자들 및 이들의 용도 - Google Patents

비복제성 바이러스유래 입자들 및 이들의 용도 Download PDF

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KR102167497B1
KR102167497B1 KR1020157019923A KR20157019923A KR102167497B1 KR 102167497 B1 KR102167497 B1 KR 102167497B1 KR 1020157019923 A KR1020157019923 A KR 1020157019923A KR 20157019923 A KR20157019923 A KR 20157019923A KR 102167497 B1 KR102167497 B1 KR 102167497B1
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KR20150112957A (ko
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다비드 콘래드
코리 바텐척
파브리스 르부프
존 카메론 벨
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셀베럼 인크
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/766—Rhabdovirus, e.g. vesicular stomatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
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    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
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    • C12N2760/20011—Rhabdoviridae
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    • C12N2760/20263—Methods of inactivation or attenuation by chemical treatment

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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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KR1020157019923A 2012-12-21 2013-12-20 비복제성 바이러스유래 입자들 및 이들의 용도 Expired - Fee Related KR102167497B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261740856P 2012-12-21 2012-12-21
US61/740,856 2012-12-21
US201361835310P 2013-06-14 2013-06-14
US61/835,310 2013-06-14
PCT/CA2013/051009 WO2014094182A1 (en) 2012-12-21 2013-12-20 Non-replicating virus-derived particles and uses thereof

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KR20150112957A KR20150112957A (ko) 2015-10-07
KR102167497B1 true KR102167497B1 (ko) 2020-10-20

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US (2) US11110138B2 (https=)
EP (1) EP2935569B1 (https=)
JP (2) JP6612619B2 (https=)
KR (1) KR102167497B1 (https=)
CN (1) CN105121636A (https=)
AU (1) AU2013362761B2 (https=)
BR (1) BR112015015045A8 (https=)
CA (1) CA2896162C (https=)
CL (1) CL2015001738A1 (https=)
ES (1) ES2745599T3 (https=)
IL (1) IL239486B (https=)
MX (1) MX376266B (https=)
MY (1) MY174912A (https=)
PH (1) PH12015501442A1 (https=)
RU (1) RU2705556C2 (https=)
SG (2) SG11201504843UA (https=)
WO (1) WO2014094182A1 (https=)

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WO2014094182A1 (en) * 2012-12-21 2014-06-26 Ottawa Hospital Research Institute Non-replicating virus-derived particles and uses thereof
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
CN109985244A (zh) * 2017-12-29 2019-07-09 广州威溶特医药科技有限公司 E3连接酶抑制剂和溶瘤病毒在制备抗肿瘤药物的应用
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
CN109432098B (zh) * 2018-11-20 2021-04-13 天津大学 化合物ps-341在制备小rna病毒科肠道病毒属病毒抑制剂的应用
EP3708176A1 (en) * 2019-03-15 2020-09-16 Centre National De La Recherche Scientifique -Cnrs- Mutant vsv ectodomain polypeptide and uses thereof

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JP2005537802A (ja) 2002-09-09 2005-12-15 ユニバーシティ・オブ・テネシー・リサーチ・ファウンデーション ラブドウイルスの組み換え型変異体及びその使用方法
JP4708027B2 (ja) * 2002-10-01 2011-06-22 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 抗癌組成物および抗感染疾患組成物ならびにこれらを使用する方法
AU2003279770A1 (en) 2002-10-01 2004-04-23 Novartis Vaccines And Diagnostics, Inc. Anti-cancer and anti-infectious disease compositions and methods for using same
CN100579579C (zh) * 2002-10-01 2010-01-13 诺华疫苗和诊断公司 抗癌及抗感染性疾病组合物及其使用方法
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CN105121636A (zh) 2015-12-02
US20210346441A1 (en) 2021-11-11
AU2013362761A1 (en) 2015-07-16
CA2896162C (en) 2021-10-12
JP2016501538A (ja) 2016-01-21
SG10201704903YA (en) 2017-07-28
US11110138B2 (en) 2021-09-07
CL2015001738A1 (es) 2015-12-18
IL239486B (en) 2019-08-29
NZ709439A (en) 2020-09-25
MX376266B (es) 2025-03-07
MY174912A (en) 2020-05-21
RU2015128766A (ru) 2017-01-26
EP2935569B1 (en) 2019-05-01
BR112015015045A8 (pt) 2018-01-23
JP6612619B2 (ja) 2019-11-27
CA2896162A1 (en) 2014-06-26
JP2020014467A (ja) 2020-01-30
RU2705556C2 (ru) 2019-11-07
MX2015008155A (es) 2016-02-05
EP2935569A4 (en) 2016-08-03
PH12015501442A1 (en) 2015-09-14
EP2935569A1 (en) 2015-10-28
AU2013362761B2 (en) 2019-08-01
WO2014094182A1 (en) 2014-06-26
US20150320810A1 (en) 2015-11-12
IL239486A0 (en) 2015-07-30
SG11201504843UA (en) 2015-07-30
HK1210624A1 (en) 2016-04-29
ES2745599T3 (es) 2020-03-02
KR20150112957A (ko) 2015-10-07

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