RU2705556C2 - Нереплицируемые происходящие от вирусов частицы и их применение - Google Patents

Нереплицируемые происходящие от вирусов частицы и их применение Download PDF

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RU2705556C2
RU2705556C2 RU2015128766A RU2015128766A RU2705556C2 RU 2705556 C2 RU2705556 C2 RU 2705556C2 RU 2015128766 A RU2015128766 A RU 2015128766A RU 2015128766 A RU2015128766 A RU 2015128766A RU 2705556 C2 RU2705556 C2 RU 2705556C2
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virus
nrrp
cells
cell
rna
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Дэвид КОНРАД
Кори БАТЕНЧУК
Фабрис ЛЕБЕФ
Джон Камерон БЕЛЛ
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Келверум Инк.
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    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/766Rhabdovirus, e.g. vesicular stomatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
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    • C12N2760/20011Rhabdoviridae
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    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261Methods of inactivation or attenuation
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261Methods of inactivation or attenuation
    • C12N2760/20263Methods of inactivation or attenuation by chemical treatment

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RU2015128766A 2012-12-21 2013-12-20 Нереплицируемые происходящие от вирусов частицы и их применение RU2705556C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261740856P 2012-12-21 2012-12-21
US61/740,856 2012-12-21
US201361835310P 2013-06-14 2013-06-14
US61/835,310 2013-06-14
PCT/CA2013/051009 WO2014094182A1 (en) 2012-12-21 2013-12-20 Non-replicating virus-derived particles and uses thereof

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RU2015128766A RU2015128766A (ru) 2017-01-26
RU2705556C2 true RU2705556C2 (ru) 2019-11-07

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US (2) US11110138B2 (https=)
EP (1) EP2935569B1 (https=)
JP (2) JP6612619B2 (https=)
KR (1) KR102167497B1 (https=)
CN (1) CN105121636A (https=)
AU (1) AU2013362761B2 (https=)
BR (1) BR112015015045A8 (https=)
CA (1) CA2896162C (https=)
CL (1) CL2015001738A1 (https=)
ES (1) ES2745599T3 (https=)
IL (1) IL239486B (https=)
MX (1) MX376266B (https=)
MY (1) MY174912A (https=)
PH (1) PH12015501442A1 (https=)
RU (1) RU2705556C2 (https=)
SG (2) SG11201504843UA (https=)
WO (1) WO2014094182A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014094182A1 (en) * 2012-12-21 2014-06-26 Ottawa Hospital Research Institute Non-replicating virus-derived particles and uses thereof
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
CN109985244A (zh) * 2017-12-29 2019-07-09 广州威溶特医药科技有限公司 E3连接酶抑制剂和溶瘤病毒在制备抗肿瘤药物的应用
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
CN109432098B (zh) * 2018-11-20 2021-04-13 天津大学 化合物ps-341在制备小rna病毒科肠道病毒属病毒抑制剂的应用
EP3708176A1 (en) * 2019-03-15 2020-09-16 Centre National De La Recherche Scientifique -Cnrs- Mutant vsv ectodomain polypeptide and uses thereof

Citations (5)

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WO2004030631A2 (en) * 2002-10-01 2004-04-15 Chiron Corporation Anti-cancer and anti-infectious disease compositions and methods for using same
US20050260601A1 (en) * 2002-09-09 2005-11-24 Whitt Michael A Recombinant mutants of rhabdovirus and methods of use thereof
RU2270685C2 (ru) * 2000-06-26 2006-02-27 Веллстат Байолоджикс Корпорейшн Удаление клеток с использованием вирусов
US20110223148A1 (en) * 2008-09-16 2011-09-15 Genomidea Inc. Therapeutic/prophylactic agent for prostate cancer
WO2012103510A2 (en) * 2011-01-27 2012-08-02 Lentigen Cororation Advanced prime and boost vacinne

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JP4708027B2 (ja) * 2002-10-01 2011-06-22 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド 抗癌組成物および抗感染疾患組成物ならびにこれらを使用する方法
CN100579579C (zh) * 2002-10-01 2010-01-13 诺华疫苗和诊断公司 抗癌及抗感染性疾病组合物及其使用方法
DE602004018284D1 (de) 2003-03-27 2009-01-22 Ottawa Health Research Inst Mutante vesicular stomatitis viren und deren verwendungen
US7807176B2 (en) * 2004-03-19 2010-10-05 Genomidea, Inc. Polypeptide promoting vascular endothelial cell growth
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RU2270685C2 (ru) * 2000-06-26 2006-02-27 Веллстат Байолоджикс Корпорейшн Удаление клеток с использованием вирусов
US20050260601A1 (en) * 2002-09-09 2005-11-24 Whitt Michael A Recombinant mutants of rhabdovirus and methods of use thereof
WO2004030631A2 (en) * 2002-10-01 2004-04-15 Chiron Corporation Anti-cancer and anti-infectious disease compositions and methods for using same
US20110223148A1 (en) * 2008-09-16 2011-09-15 Genomidea Inc. Therapeutic/prophylactic agent for prostate cancer
WO2012103510A2 (en) * 2011-01-27 2012-08-02 Lentigen Cororation Advanced prime and boost vacinne

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BERGMAN I. et al. Preferential targeting of vesicular stomatitis virus to breast cancer cells. Virology, 2004, V.330, P.24-33 (стр.24, 29-32). BRUN J. et al. Identification of genetically modified Maraba virus as an oncolytic Rhabdovirus. Molecular therapy, 2010, V.18, No.8, P.1440-1449, (стр.1440, 1446-1448). *
BRUN J. et al. Identification of genetically modified Maraba virus as an oncolytic Rhabdovirus. Molecular therapy, 2010, V.18, No.8, P.1440-1449, (стр.1440, 1446-1448). *
KUROOKA M., KANEDA Y. Inactivated Senday virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer research, 2007, V.67, No.1, P.227-236 (227-228, 233-235). *
ZAJAC P. et al. Phase I/II clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-Restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients. Human gene therapy, 2003, V.14, P.1497-1510 (стр.1497-1501, 1505-1507). *
ZAJAC P. et al. Phase I/II clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-Restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients. Human gene therapy, 2003, V.14, P.1497-1510 (стр.1497-1501, 1505-1507). KUROOKA M., KANEDA Y. Inactivated Senday virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer research, 2007, V.67, No.1, P.227-236 (227-228, 233-235). *

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CN105121636A (zh) 2015-12-02
US20210346441A1 (en) 2021-11-11
AU2013362761A1 (en) 2015-07-16
CA2896162C (en) 2021-10-12
JP2016501538A (ja) 2016-01-21
SG10201704903YA (en) 2017-07-28
US11110138B2 (en) 2021-09-07
CL2015001738A1 (es) 2015-12-18
IL239486B (en) 2019-08-29
NZ709439A (en) 2020-09-25
MX376266B (es) 2025-03-07
MY174912A (en) 2020-05-21
RU2015128766A (ru) 2017-01-26
EP2935569B1 (en) 2019-05-01
BR112015015045A8 (pt) 2018-01-23
JP6612619B2 (ja) 2019-11-27
CA2896162A1 (en) 2014-06-26
JP2020014467A (ja) 2020-01-30
MX2015008155A (es) 2016-02-05
KR102167497B1 (ko) 2020-10-20
EP2935569A4 (en) 2016-08-03
PH12015501442A1 (en) 2015-09-14
EP2935569A1 (en) 2015-10-28
AU2013362761B2 (en) 2019-08-01
WO2014094182A1 (en) 2014-06-26
US20150320810A1 (en) 2015-11-12
IL239486A0 (en) 2015-07-30
SG11201504843UA (en) 2015-07-30
HK1210624A1 (en) 2016-04-29
ES2745599T3 (es) 2020-03-02
KR20150112957A (ko) 2015-10-07

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