BR112015014152A2 - - Google Patents
Info
- Publication number
- BR112015014152A2 BR112015014152A2 BR112015014152A BR112015014152A BR112015014152A2 BR 112015014152 A2 BR112015014152 A2 BR 112015014152A2 BR 112015014152 A BR112015014152 A BR 112015014152A BR 112015014152 A BR112015014152 A BR 112015014152A BR 112015014152 A2 BR112015014152 A2 BR 112015014152A2
- Authority
- BR
- Brazil
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120154834 | 2012-12-27 | ||
| KR10-2012-0154834 | 2012-12-27 | ||
| KR10-2013-0008580 | 2013-01-25 | ||
| KR20130008580 | 2013-01-25 | ||
| KR10-2013-0034670 | 2013-03-29 | ||
| KR20130034670 | 2013-03-29 | ||
| PCT/KR2013/012312 WO2014104818A1 (en) | 2012-12-27 | 2013-12-27 | Detection of target nucleic acid sequence by pto cleavage and extension-dependent non-hybridization assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015014152A2 true BR112015014152A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2017-08-22 |
| BR112015014152B1 BR112015014152B1 (pt) | 2023-01-24 |
Family
ID=51021756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015014152-8A BR112015014152B1 (pt) | 2012-12-27 | 2013-12-27 | Método e kit para detectar uma sequência de ácido nucleico alvo por ensaio de clivagem de pto e não hibridização dependente de extensão |
Country Status (12)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017213458A1 (en) | 2016-06-10 | 2017-12-14 | Seegene, Inc. | Methods for preparing tagging oligonucleotides |
| EP3479101B1 (en) | 2016-06-30 | 2023-12-13 | Seegene, Inc. | Apparatus and method for amplificating nucleic acid |
| EP3523452A4 (en) | 2016-10-06 | 2020-06-10 | Seegene, Inc. | METHODS OF PREPARING OLIGONUCLEOTIDES TO DETECT TARGET NUCLEIC ACID MOLECULES IN SAMPLES |
| CA3049833A1 (en) * | 2016-12-23 | 2018-06-28 | Albert-Ludwigs-Universitat Freiburg | Two-piece mediator probe |
| ES2972231T3 (es) | 2016-12-29 | 2024-06-11 | Seegene Inc | Procedimiento para reducir la formación de dímeros de cebadores y aumentar la eficacia de la amplificación |
| KR102408564B1 (ko) | 2017-03-28 | 2022-06-14 | 주식회사 씨젠 | 타겟 핵산 서열의 존재를 결정하기 위한 분석 시그널 |
| CN108823287B (zh) | 2017-04-28 | 2019-04-12 | 厦门大学 | 一种检测靶核酸序列的方法 |
| CN107236815A (zh) * | 2017-07-18 | 2017-10-10 | 江西贤聚景欣医药生物科技有限公司 | 用于靶核酸序列检测的多重淬灭荧光探针及方法 |
| WO2019045532A2 (en) | 2017-08-31 | 2019-03-07 | Seegene, Inc. | EVALUATION OF COMPONENT PERFORMANCE USING A PAIR OF DIMER FORMER PRIMERS |
| KR102345601B1 (ko) | 2017-09-29 | 2021-12-30 | 주식회사 씨젠 | Pto 절단 및 연장-의존적 연장 분석에 의한 타겟 핵산 서열의 검출 |
| WO2019135567A1 (en) | 2018-01-05 | 2019-07-11 | Seegene, Inc. . | Method for determining the presence or absence of m. tuberculosis, m. bovis and m. bovis bcg in a sample |
| BR112020019755A2 (pt) | 2018-04-20 | 2021-01-26 | Seegene, Inc. | método e aparelho para detectar uma pluralidade de sequências de ácidos nucleicos alvo na amostra |
| WO2020122679A1 (en) | 2018-12-14 | 2020-06-18 | Seegene, Inc. | Method for detecting a target analyte in a sample using an s-shaped function for a slope data set |
| CN113195734B (zh) * | 2018-12-20 | 2024-12-24 | 豪夫迈·罗氏有限公司 | 通过固相分子成像检测靶核酸 |
| KR20240058112A (ko) | 2021-09-17 | 2024-05-03 | 주식회사 씨젠 | 합성 비자연 염기를 포함하는 태그 올리고뉴클레오타이드를 이용한 타겟 핵산 서열의 검출 |
| EP4511509A1 (de) * | 2022-04-22 | 2025-02-26 | Hahn-Schickard-Gesellschaft für angewandte Forschung e. V. | Nukleinsäurenachweis in einer pcr mittels eines zielsequenz-unspezifischem modularer reporterkomplexes |
| EP4265734A1 (de) * | 2022-04-22 | 2023-10-25 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Nukleinsäurenachweis in einer pcr mittels eines zielsequenz-unspezifischem modularer reporterkomplexes |
| EP4603593A1 (en) | 2022-10-14 | 2025-08-20 | Seegene, Inc. | Method for detecting target nucleic acid in sample using two probes with different tm values |
| EP4372100A1 (en) * | 2022-11-15 | 2024-05-22 | Stilla Technologies | Data analysis method for multiplex digital pcr using color-combination |
| KR20250110818A (ko) | 2022-11-16 | 2025-07-21 | 주식회사 씨젠 | 퀀칭-pto 절단 및 연장(quenching-pto cleavage and extension；q-ptoce) 어세이에 의한 타겟 핵산의 검출 |
| WO2025005717A1 (ko) * | 2023-06-30 | 2025-01-02 | 주식회사 씨젠 | Hto 절단 및 자기-연장 어세이에 의해 샘플 내의 타겟 핵산을 검출하는 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5994069A (en) | 1996-01-24 | 1999-11-30 | Third Wave Technologies, Inc. | Detection of nucleic acids by multiple sequential invasive cleavages |
| US5541311A (en) | 1992-12-07 | 1996-07-30 | Third Wave Technologies, Inc. | Nucleic acid encoding synthesis-deficient thermostable DNA polymerase |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| US7381532B2 (en) | 1999-10-29 | 2008-06-03 | Stratagene California | Compositions and methods for the detection of a nucleic acid using a cleavage reaction |
| US6893819B1 (en) | 2000-11-21 | 2005-05-17 | Stratagene California | Methods for detection of a nucleic acid by sequential amplification |
| US7601497B2 (en) * | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7309573B2 (en) | 2000-11-21 | 2007-12-18 | Stratagene California | Methods for detection of a nucleic acid by sequential amplification |
| KR20020063359A (ko) | 2001-01-27 | 2002-08-03 | 일렉트론 바이오 (주) | 핵산 및 올리거뉴클레오티드의 상보적 이중결합의 특정서열에 특이적으로 반응하는 절단기법을 이용한 핵산 혼성분석 방법 및 장치 |
| GB0205455D0 (en) * | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
| CN101076537B (zh) * | 2003-11-19 | 2012-07-04 | 阿莱洛吉克生物科学公司 | 标记有多个荧光团的寡核苷酸 |
| JP5286261B2 (ja) * | 2006-07-17 | 2013-09-11 | ブランディーズ・ユニバーシティ | 特殊化オリゴヌクレオチドならびに核酸の増幅および検出でのその使用 |
| US20090023151A1 (en) * | 2006-08-30 | 2009-01-22 | Dawson Elliott P | Method For The Labeling And Detection Of Small Polynucleotides |
| WO2008083261A1 (en) | 2006-12-29 | 2008-07-10 | Applera Corporation | Systems and methods for detecting nucleic acids |
| MX2017015093A (es) * | 2011-01-11 | 2023-03-10 | Seegene Inc | Detección de secuencias de ácido nucleico objetivo mediante ensayo de escisión y extensión del pto. |
| EP2691543B1 (en) * | 2011-03-29 | 2017-11-01 | Seegene, Inc. | Detection of target nucleic acid sequence by pto cleavage and extension-dependent cleavage |
| WO2012150749A1 (en) * | 2011-05-04 | 2012-11-08 | Seegene, Inc. | Detection of target nucleic acid sequences by po cleavage and hybridization |
-
2013
- 2013-12-27 MX MX2015008494A patent/MX361191B/es active IP Right Grant
- 2013-12-27 CN CN201380068241.3A patent/CN104903465B/zh active Active
- 2013-12-27 RU RU2015130335A patent/RU2620958C2/ru active
- 2013-12-27 JP JP2015550327A patent/JP6178430B2/ja active Active
- 2013-12-27 EP EP13868457.6A patent/EP2943586B1/en active Active
- 2013-12-27 CA CA2896213A patent/CA2896213C/en active Active
- 2013-12-27 AU AU2013371128A patent/AU2013371128B2/en active Active
- 2013-12-27 ES ES13868457.6T patent/ES2653642T3/es active Active
- 2013-12-27 KR KR1020157017974A patent/KR101760267B1/ko active Active
- 2013-12-27 WO PCT/KR2013/012312 patent/WO2014104818A1/en active Application Filing
- 2013-12-27 BR BR112015014152-8A patent/BR112015014152B1/pt active IP Right Grant
- 2013-12-27 US US14/655,847 patent/US9783845B2/en active Active
-
2017
- 2017-09-07 US US15/697,617 patent/US20180057869A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2896213A1 (en) | 2014-07-03 |
| US9783845B2 (en) | 2017-10-10 |
| MX2015008494A (es) | 2015-09-10 |
| AU2013371128B2 (en) | 2017-08-10 |
| CN104903465B (zh) | 2017-04-26 |
| US20180057869A1 (en) | 2018-03-01 |
| ES2653642T3 (es) | 2018-02-08 |
| EP2943586A1 (en) | 2015-11-18 |
| EP2943586A4 (en) | 2016-09-28 |
| US20160060690A1 (en) | 2016-03-03 |
| JP2016502861A (ja) | 2016-02-01 |
| MX361191B (es) | 2018-11-29 |
| AU2013371128A1 (en) | 2015-08-13 |
| JP6178430B2 (ja) | 2017-08-09 |
| BR112015014152B1 (pt) | 2023-01-24 |
| RU2015130335A (ru) | 2017-01-30 |
| EP2943586B1 (en) | 2017-09-20 |
| KR20150093766A (ko) | 2015-08-18 |
| CN104903465A (zh) | 2015-09-09 |
| CA2896213C (en) | 2018-12-11 |
| KR101760267B1 (ko) | 2017-07-24 |
| WO2014104818A1 (en) | 2014-07-03 |
| RU2620958C2 (ru) | 2017-05-30 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B09W | Correction of the decision to grant [chapter 9.1.4 patent gazette] |
Free format text: A NOTIFICACAO FOI EFETUADA COM INCORRECAO NO QUADRO 1 DO PARECER DE DEFERIMENTO. |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/12/2013, OBSERVADAS AS CONDICOES LEGAIS |