BR112014028564A2 - composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e um componente de ácido salicílico - Google Patents
composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e um componente de ácido salicílicoInfo
- Publication number
- BR112014028564A2 BR112014028564A2 BR112014028564A BR112014028564A BR112014028564A2 BR 112014028564 A2 BR112014028564 A2 BR 112014028564A2 BR 112014028564 A BR112014028564 A BR 112014028564A BR 112014028564 A BR112014028564 A BR 112014028564A BR 112014028564 A2 BR112014028564 A2 BR 112014028564A2
- Authority
- BR
- Brazil
- Prior art keywords
- pyran
- spiro
- indole
- dihydro
- cyclohexane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12003936 | 2012-05-18 | ||
PCT/EP2013/001467 WO2013170968A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro [cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014028564A2 true BR112014028564A2 (pt) | 2017-06-27 |
Family
ID=48468207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014028564A BR112014028564A2 (pt) | 2012-05-18 | 2013-05-16 | composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e um componente de ácido salicílico |
Country Status (23)
Country | Link |
---|---|
US (1) | US9855286B2 (pt) |
EP (1) | EP2852386B1 (pt) |
JP (1) | JP6116675B2 (pt) |
CN (1) | CN104284661A (pt) |
AU (1) | AU2013262074B2 (pt) |
BR (1) | BR112014028564A2 (pt) |
CA (1) | CA2873640A1 (pt) |
CY (1) | CY1119692T1 (pt) |
DK (1) | DK2852386T3 (pt) |
EA (1) | EA026642B1 (pt) |
ES (1) | ES2654146T3 (pt) |
HK (1) | HK1204941A1 (pt) |
HR (1) | HRP20171927T1 (pt) |
HU (1) | HUE035930T2 (pt) |
IL (1) | IL235656B (pt) |
LT (1) | LT2852386T (pt) |
MX (1) | MX352595B (pt) |
NO (1) | NO2852386T3 (pt) |
PL (1) | PL2852386T3 (pt) |
PT (1) | PT2852386T (pt) |
RS (1) | RS56674B1 (pt) |
SI (1) | SI2852386T1 (pt) |
WO (1) | WO2013170968A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2016208779B2 (en) | 2015-01-23 | 2020-11-12 | Grunenthal Gmbh | Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS584720A (ja) | 1981-06-26 | 1983-01-11 | ザ・アツプジヨン・カンパニ− | 鎮痛用医薬組成物 |
US4389393A (en) | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
US4404208A (en) | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and tiflamizole |
IE55189B1 (en) | 1982-07-08 | 1990-06-20 | Wyeth John & Brother Ltd | Pharmaceutical compositions |
US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
DE3665538D1 (en) | 1985-01-23 | 1989-10-19 | Asta Pharma Ag | Synergistic combination of flupirtin and non-steroidal anti-phlogistics |
WO1990014337A1 (en) | 1989-05-22 | 1990-11-29 | Biochemical Veterinary Research | Divalent metal salts of indomethacin |
CA2112378A1 (en) | 1991-07-04 | 1993-01-21 | Masakazu Kanazawa | Analgesic preparation |
US5339362A (en) | 1992-01-07 | 1994-08-16 | Rockford Corporation | Automotive audio system |
JPH05221857A (ja) | 1992-02-14 | 1993-08-31 | Arakusu:Kk | 配合解熱鎮痛剤 |
US5472711A (en) | 1992-07-30 | 1995-12-05 | Edward Mendell Co., Inc. | Agglomerated hydrophilic complexes with multi-phasic release characteristics |
US5330761A (en) | 1993-01-29 | 1994-07-19 | Edward Mendell Co. Inc. | Bioadhesive tablet for non-systemic use products |
JPH08511522A (ja) | 1993-06-07 | 1996-12-03 | メルク エンド カンパニー インコーポレーテッド | ニューロキニンアンタゴニストとしてのスピロ置換アザ環 |
US5455046A (en) | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US5399362A (en) | 1994-04-25 | 1995-03-21 | Edward Mendell Co., Inc. | Once-a-day metoprolol oral dosage form |
US5914129A (en) * | 1996-07-23 | 1999-06-22 | Mauskop; Alexander | Analgesic composition for treatment of migraine headaches |
RS49982B (sr) | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
EA004032B1 (ru) | 1998-09-10 | 2003-12-25 | Нюкомед Данмарк А/С | Фармацевтические композиции лекарственных веществ с быстрым высвобождением |
WO2000028980A2 (en) | 1998-11-13 | 2000-05-25 | Eli Lilly And Company | Combination of duloxetine with non-steroidal antiinflammatory drug for treating pain |
ATE279920T1 (de) | 2000-12-28 | 2004-11-15 | Fresenius Kabi Austria Gmbh | Stabile infusionslösung von diclofenac-salzen, deren herstellung und verwendung |
MXPA04007242A (es) | 2002-01-28 | 2004-10-29 | Pfizer | Compuestos de espiropiperidina n-sustituidos como ligandos para el receptor orl-1. |
SI1374906T1 (sl) | 2002-06-17 | 2007-10-31 | Chiesi Farma Spa | Postopek za pripravo inkluzijskih spojin piroksakama: beta-ciklodekstrina |
DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
DE10257824B4 (de) | 2002-12-10 | 2004-11-11 | Kochem, Hans-Günter, Dr. | Zusammensetzung zur Schmerzbehandlung, insbesondere zur Behandlung von Gelenkschmerzen |
US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
US7132452B2 (en) | 2003-03-10 | 2006-11-07 | Fang-Yu Lee | Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection |
DE10360792A1 (de) | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
EP1893610A2 (en) | 2005-06-17 | 2008-03-05 | Pfizer, Inc. | Alpha-(aryl-or heteroaryl-methyl)-beta piperidino propanamide compounds as orl1-receptor antagonists |
ES2356093T3 (es) | 2006-04-28 | 2011-04-04 | Grünenthal GmbH | Combinación farmacéutica que comprende 3-(3-dimetilamino-1-etil-2-metilpropil)fenol y paracetamol. |
PL2012763T3 (pl) | 2006-04-28 | 2011-08-31 | Gruenenthal Gmbh | Kombinacja farmaceutyczna zawierająca 3-(3-dimetyloamino-1-etylo-2-metylo-propylo)-fenol i NSAID |
CN101147735A (zh) | 2006-09-19 | 2008-03-26 | 沈阳华泰药物研究有限公司 | 注射用药物组合物及其药盒 |
DE102006046745A1 (de) | 2006-09-29 | 2008-04-03 | Grünenthal GmbH | Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz |
DE102006056458A1 (de) | 2006-11-28 | 2008-05-29 | Grünenthal GmbH | Arzneimittelzubereitung von Tramadol und Acetaminophen |
JP5452494B2 (ja) | 2007-10-09 | 2014-03-26 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | ベンフォチアミンと1または2種以上の医薬活性剤とを含む神経因性の疼痛状態の処置のための医薬組成物 |
CN100560061C (zh) | 2008-06-20 | 2009-11-18 | 海南锦瑞制药股份有限公司 | 一种氯诺昔康冻干粉针剂及其制备方法 |
JP2012501985A (ja) | 2008-09-05 | 2012-01-26 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 6−ジメチルアミノメチル−1−(3−メトキシフェニル)−シクロヘキサン−1,3−ジオールとパラセタモールを含む医薬の組み合わせ |
KR20110065488A (ko) | 2008-09-05 | 2011-06-15 | 그뤼넨탈 게엠베하 | 6-디메틸아미노메틸-1-(3-메톡시-페닐)-사이클로헥산-1,3-디올 및 nsaid를 포함하는 약제학적 병용물 |
TR201904388T4 (tr) | 2008-09-05 | 2019-05-21 | Gruenenthal Gmbh | Pregabalin veya gabapentin ve 3-(3-dimetilamino-1-etil-2-metil-propil)-fenolün farmasötik kombinasyonu. |
RU2631481C2 (ru) | 2010-08-04 | 2017-09-22 | Грюненталь Гмбх | ЛЕКАРСТВЕННАЯ ДОЗИРОВАННАЯ ФОРМА, КОТОРАЯ СОДЕРЖИТ 6'-ФТОР-(N-МЕТИЛ-ИЛИ N, N-ДИМЕТИЛ-)-4-ФЕНИЛ-4', 9'-ДИГИДРО-3' Н-СПИРО[ЦИКЛОГЕКСАН-1, 1'-ПИРАНО[3, 4, b] ИНДОЛ]-4-АМИН ДЛЯ ЛЕЧЕНИЯ НОЦИЦЕПТИВНОЙ БОЛИ |
CN103079548A (zh) | 2010-08-04 | 2013-05-01 | 格吕伦塔尔有限公司 | 含有6’-氟-(N-甲基-或N,N-二甲基)-4-苯基-4’,9’-二氢-3’H-螺[环己烷-1,1’-吡喃并[3,4,b]吲哚]-4-胺的药物剂型 |
HUE025322T2 (en) | 2010-08-04 | 2016-02-29 | Gruenenthal Gmbh | A pharmaceutical dosage form comprising 6'-fluoro- (N-methyl or N, N-dimethyl) -4-phenyl-4 ', 9'-dihydro-3'H-spiro [cyclohexane-1,1'-pyran [3, 4, b] indole] -4-amine |
US9320729B2 (en) | 2012-05-18 | 2016-04-26 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative |
FR3010236B1 (fr) | 2013-09-05 | 2017-01-13 | Arkema France | Additifs pour ameliorer la conductivite ionique des electrodes de batteries li-ion |
-
2013
- 2013-05-13 US US13/892,813 patent/US9855286B2/en not_active Expired - Fee Related
- 2013-05-16 JP JP2015511954A patent/JP6116675B2/ja active Active
- 2013-05-16 CN CN201380025659.6A patent/CN104284661A/zh active Pending
- 2013-05-16 DK DK13723673.3T patent/DK2852386T3/en active
- 2013-05-16 EA EA201401267A patent/EA026642B1/ru not_active IP Right Cessation
- 2013-05-16 MX MX2014012765A patent/MX352595B/es active IP Right Grant
- 2013-05-16 CA CA2873640A patent/CA2873640A1/en not_active Abandoned
- 2013-05-16 NO NO13723673A patent/NO2852386T3/no unknown
- 2013-05-16 PT PT137236733T patent/PT2852386T/pt unknown
- 2013-05-16 SI SI201330884T patent/SI2852386T1/en unknown
- 2013-05-16 BR BR112014028564A patent/BR112014028564A2/pt active Search and Examination
- 2013-05-16 RS RS20171290A patent/RS56674B1/sr unknown
- 2013-05-16 HU HUE13723673A patent/HUE035930T2/hu unknown
- 2013-05-16 LT LTEP13723673.3T patent/LT2852386T/lt unknown
- 2013-05-16 PL PL13723673T patent/PL2852386T3/pl unknown
- 2013-05-16 AU AU2013262074A patent/AU2013262074B2/en not_active Ceased
- 2013-05-16 WO PCT/EP2013/001467 patent/WO2013170968A1/en active Application Filing
- 2013-05-16 ES ES13723673.3T patent/ES2654146T3/es active Active
- 2013-05-16 EP EP13723673.3A patent/EP2852386B1/en active Active
-
2014
- 2014-11-12 IL IL235656A patent/IL235656B/en active IP Right Grant
-
2015
- 2015-06-11 HK HK15105572.8A patent/HK1204941A1/xx not_active IP Right Cessation
-
2017
- 2017-12-13 HR HRP20171927TT patent/HRP20171927T1/hr unknown
- 2017-12-18 CY CY20171101323T patent/CY1119692T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP2852386B1 (en) | 2017-11-15 |
RS56674B1 (sr) | 2018-03-30 |
US20130317076A1 (en) | 2013-11-28 |
US9855286B2 (en) | 2018-01-02 |
LT2852386T (lt) | 2018-01-10 |
IL235656B (en) | 2018-08-30 |
HUE035930T2 (hu) | 2018-06-28 |
HRP20171927T1 (hr) | 2018-01-26 |
CY1119692T1 (el) | 2018-04-04 |
AU2013262074B2 (en) | 2018-01-18 |
PL2852386T3 (pl) | 2018-02-28 |
JP6116675B2 (ja) | 2017-04-19 |
EA201401267A1 (ru) | 2016-05-31 |
ES2654146T3 (es) | 2018-02-12 |
CN104284661A (zh) | 2015-01-14 |
PT2852386T (pt) | 2018-01-04 |
DK2852386T3 (en) | 2018-01-08 |
NO2852386T3 (pt) | 2018-04-14 |
IL235656A0 (en) | 2015-01-29 |
AU2013262074A1 (en) | 2015-01-22 |
MX2014012765A (es) | 2014-11-21 |
JP2015516448A (ja) | 2015-06-11 |
EP2852386A1 (en) | 2015-04-01 |
SI2852386T1 (en) | 2018-04-30 |
CA2873640A1 (en) | 2013-11-21 |
MX352595B (es) | 2017-11-30 |
WO2013170968A1 (en) | 2013-11-21 |
EA026642B1 (ru) | 2017-04-28 |
HK1204941A1 (en) | 2015-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1204992A1 (en) | Topical ophthalmological pharmaceutical composition containing sunitinib | |
CU24163B1 (es) | Composición farmacéutica oftalmológica tópica que contiene regorafenib | |
HK1204942A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1-pyrano- [3,4,b]indol]-4-amine and a propionic acid derivative (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- | |
HK1204937A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1-pyrano [3,4,b]indol]-4-amine and an anticonvulsant (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- | |
BR112014028574A2 (pt) | composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e um gabapentinoide | |
BR112014028564A2 (pt) | composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e um componente de ácido salicílico | |
HK1204938A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1-pyrano [3,4,b]indol]-4-amine and a nsar (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- nsar | |
BR112014028569A2 (pt) | composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e um oxicam | |
BR112014028562A2 (pt) | composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n , n-dimetil-4 ,9-di-hidro-3h-espiro[ciclo-hexano-1 ,1-pirano-[3,4,b]indol]-4-amina e antidepressivos | |
BR112014028557A2 (pt) | composição farmacêutica compreendendo ( 1r , 4r )-6-fluoro-n ,n-dimetil-4-fenil-4 ,9-di-hidro-3h-espiro[ciclohexano-1 ,1-pirano-[3,4,b]indol]-4- amina e um anticonvulsivo | |
HK1204940A1 (en) | Pharmaceutical composition comprising (1r,4r)-6-fluoro-n,n-dimethyl- 4-phenyl-4,9-dihydro-3h-spiro[cyclohexane-1,1- pyrano[3,4,b]indol]-4-amine and paracetamol or propacetamol (1r4r)-6--nn--4--49--3h-[- 11-[34b]]-4- | |
HK1199258A1 (zh) | '- '- '- '-氟代- -二甲基- -苯基- ', '-二氫- -螺環- 環己烷- '-吡喃並 吲哚基 -鹽酸胺的固體形式 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |