BR112014019036A2 - Processo de preparação de derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e 3,5-bis(fluoroalquil)pirazóis - Google Patents

Processo de preparação de derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e 3,5-bis(fluoroalquil)pirazóis

Info

Publication number
BR112014019036A2
BR112014019036A2 BR112014019036A BR112014019036A BR112014019036A2 BR 112014019036 A2 BR112014019036 A2 BR 112014019036A2 BR 112014019036 A BR112014019036 A BR 112014019036A BR 112014019036 A BR112014019036 A BR 112014019036A BR 112014019036 A2 BR112014019036 A2 BR 112014019036A2
Authority
BR
Brazil
Prior art keywords
fluoroalkyl
bis
pyrazole
carboxylic acid
pyrazoles
Prior art date
Application number
BR112014019036A
Other languages
English (en)
Other versions
BR112014019036B1 (pt
Inventor
Lui Norbert
Pazenok Sergii
Vors Jean-Pierre
R Leroux Frédéric
Giornal Florence
Original Assignee
Centre Nat Rech Scient
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Bayer Cropscience Ag filed Critical Centre Nat Rech Scient
Publication of BR112014019036A2 publication Critical patent/BR112014019036A2/pt
Publication of BR112014019036B1 publication Critical patent/BR112014019036B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated

Abstract

PROCESSO DE PREPARAÇÃO DE DERIVADOS DO ÁCIDO 3,5 BIS(FLUOROALQUIL)PIRAZOLE-4-CARBOXÍLICO E 3,5-BIS(FLUOROALQUIL)PIRAZÓIS. A presente invenção refere-se a novos derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e a um processo de preparação de derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e 3,5-bis(fluoroalquil)pirazóis.
BR112014019036-4A 2012-02-01 2013-01-31 Processo depreparação de derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e 3,5-bis(fluoroalquil)pirazóis BR112014019036B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12356001.3 2012-02-01
EP12356001.3A EP2623496A1 (de) 2012-02-01 2012-02-01 Verfahren zur Herstellung von 3,5-bis (fluoralkyl)-pyrazol-4-carbonsäure-Derivaten und 3,5-bis(fluoralkyl)-pyrazolen
PCT/EP2013/051930 WO2013113829A1 (de) 2012-02-01 2013-01-31 Verfahren zur herstellung von 3,5-bis(fluoralkyl)-pyrazol-4-carbonsäure-derivaten und 3,5-bis(fluoralkyl)-pyrazolen

Publications (2)

Publication Number Publication Date
BR112014019036A2 true BR112014019036A2 (pt) 2017-08-22
BR112014019036B1 BR112014019036B1 (pt) 2019-10-08

Family

ID=47624109

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014019036-4A BR112014019036B1 (pt) 2012-02-01 2013-01-31 Processo depreparação de derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e 3,5-bis(fluoroalquil)pirazóis

Country Status (13)

Country Link
US (2) US9309202B2 (pt)
EP (2) EP2623496A1 (pt)
JP (1) JP6155283B2 (pt)
KR (1) KR101861116B1 (pt)
CN (1) CN104245676B (pt)
BR (1) BR112014019036B1 (pt)
DK (1) DK2809653T3 (pt)
ES (1) ES2647348T3 (pt)
IL (1) IL233926B (pt)
IN (1) IN2014DN07129A (pt)
MX (1) MX362689B (pt)
TW (1) TWI609006B (pt)
WO (1) WO2013113829A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015016119A (es) * 2013-05-22 2016-03-31 Bayer Cropscience Ag Metodo para preparar derivados de 3,5-bis(fluoroalquil)pirazol.
TWI647215B (zh) * 2013-11-11 2019-01-11 德商拜耳作物科學股份有限公司 自α,α－二鹵胺製備３,５－雙鹵烷基吡唑衍生物之方法
EP3015458A1 (en) * 2014-11-03 2016-05-04 Bayer CropScience AG Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines
BR112016021874B1 (pt) 2014-03-24 2021-03-23 Bayer Cropscience Aktiengesellschaft Processo para preparar derivados de 3,5-bis(haloalquil)pirazol a partir de alfa,alfa-dihaloaminas e cetiminas e compostos
WO2015189141A1 (en) * 2014-06-11 2015-12-17 Bayer Cropscience Ag Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives via acylation of hydrazones
CN106458918B (zh) * 2014-06-11 2019-07-09 拜耳作物科学股份公司 经由酮亚胺的酰化来制备3,5-双(卤代烷基)吡唑的方法
CA3170386A1 (en) 2015-02-11 2016-08-18 Basf Se Pesticidal mixture comprising a pyrazole compound, an insecticide and a fungicide
CN107960078A (zh) * 2015-06-26 2018-04-24 拜耳作物科学股份公司 由α,α-二卤代烷基胺和酮亚胺制备含有卤代烷氧基和卤代烷硫基的取代的吡唑的方法
KR20210022049A (ko) 2018-06-18 2021-03-02 바이엘 악티엔게젤샤프트 이치환된 5(3)-피라졸 카르복실레이트, 및 에놀레이트 및 플루오로알킬아미노시약 (far) 시약으로부터의 그의 제조 방법
US11014945B2 (en) * 2019-04-06 2021-05-25 Trinapco, Inc. Sulfonyldiazoles and N-(fluorosulfonyl)azoles, and methods of making the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2004460A6 (es) * 1987-07-29 1989-01-01 Consejo Superior Investigacion Procedimiento para la preparacion de derivados de 3-5-bis-(halometil) pirazol
JP3533134B2 (ja) * 1999-02-15 2004-05-31 三井化学株式会社 フッ素化剤及びその製法と使用
JP2001192369A (ja) * 2000-01-12 2001-07-17 Mitsui Chemicals Inc フッ素含有複素環式芳香族化合物の製造方法および新規ピラゾール環化合物
DE10215292A1 (de) 2002-02-19 2003-08-28 Bayer Cropscience Ag Disubstitutierte Pyrazolylcarbocanilide
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
DE10349500A1 (de) * 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
TW200738701A (en) 2005-07-26 2007-10-16 Du Pont Fungicidal carboxamides
GB0526044D0 (en) * 2005-12-21 2006-02-01 Syngenta Ltd Novel herbicides
WO2008013622A2 (en) 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Fungicidal azocyclic amides
DE102006039909A1 (de) 2006-08-25 2008-03-13 Bayer Cropscience Ag Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten
WO2008091594A2 (en) * 2007-01-24 2008-07-31 E. I. Du Pont De Nemours And Company Fungicidal mixtures
EP2133341A1 (de) 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten
EP2100883A1 (de) 2008-03-10 2009-09-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4carbonsäure-Derivaten
JP2010083763A (ja) * 2008-09-29 2010-04-15 Mitsui Chemicals Inc ピラゾール誘導体およびその製造方法、ならびに殺菌剤

Also Published As

Publication number Publication date
CN104245676B (zh) 2016-09-21
KR20140128344A (ko) 2014-11-05
BR112014019036B1 (pt) 2019-10-08
JP6155283B2 (ja) 2017-06-28
US10035773B2 (en) 2018-07-31
US9309202B2 (en) 2016-04-12
IL233926A0 (en) 2014-09-30
KR101861116B1 (ko) 2018-05-25
EP2809653A1 (de) 2014-12-10
DK2809653T3 (da) 2017-11-27
IL233926B (en) 2018-08-30
US20160185731A1 (en) 2016-06-30
EP2809653B1 (de) 2017-08-16
WO2013113829A1 (de) 2013-08-08
MX2014009203A (es) 2014-11-12
ES2647348T3 (es) 2017-12-21
IN2014DN07129A (pt) 2015-04-24
EP2623496A1 (de) 2013-08-07
TWI609006B (zh) 2017-12-21
JP2015511227A (ja) 2015-04-16
TW201336826A (zh) 2013-09-16
US20150011779A1 (en) 2015-01-08
MX362689B (es) 2019-02-01
CN104245676A (zh) 2014-12-24

Similar Documents

Publication Publication Date Title
BR112014019036A2 (pt) Processo de preparação de derivados do ácido 3,5-bis(fluoroalquil)pirazole-4-carboxílico e 3,5-bis(fluoroalquil)pirazóis
BR112016014018B8 (pt) Processo para a preparação dos compostos de cetona (ia), e processo para a preparação dos compostos de triazol de fórmula (ic)
CR20140547A (es) Compuestos que contienen pirazol sustituido y su uso como plaguicidas
BR112015031913A2 (pt) processo para a fabricação de amino-benzoxazinonas 4-propargilatadas e sua utilização
IN2015DN01061A (pt)
BR112015002464B8 (pt) processo para a preparação de carbamat-benzoxazinona, carbamat-benzoxazinona e uso da carbamat-benzoxazinona
BR112015029399A2 (pt) produção em etapa única de uma composição de polipropileno
UA111333C2 (uk) Спосіб одержання l-аргінінової солі периндроприлу
NZ720106A (en) A process for the preparation of regadenoson
BR112012002641A2 (pt) processo de preparação de amidas de ácido carboxílico pirazol
MX350122B (es) Tinturas dispersas, su preparación y su uso.
MX362822B (es) Proceso para preparar derivados de 3,5-bis(haloalquil)pirazol a partir de a,a-dihaloaminas.
IN2014MN02254A (pt)
BR112015027707A2 (pt) Método de preparação de derivados de 3,5-bis(fluoroalquil)pirazole e compostos intermediários envolvidos nesse método
MX2015015720A (es) Proceso para preparar derivados de 3, 5-bis (fluoroalquil) pirazol a partir de a, a-dihaloaminas.
MX2016005219A (es) Tinturas acidas, proceso para su produccion y su uso.
BR112016028700A2 (pt) processo para preparação de 3,5-bis(haloalquil)pirazoles via acilação de cetiminas
EA201592221A1 (ru) Способ получения ивабрадина
EA201401045A1 (ru) Соединения для лечения заболеваний, связанных с ишемией-реперфузией
MX2016005220A (es) Tinturas acidas, proceso para su produccion y su uso.
BR112014019738A8 (pt) Processo
IN2013CH04635A (pt)
MX2016005221A (es) Tinturas acidas, proceso para su produccion y su uso.
MX2016005222A (es) Tinturas acidas, proceso para su produccion y su uso.
BR112012020613A2 (pt) processo para preparar um éter carboxilato.

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B04C Request for examination: application reinstated [chapter 4.3 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/01/2013, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/01/2013, OBSERVADAS AS CONDICOES LEGAIS