BR112012002641A2 - processo de preparação de amidas de ácido carboxílico pirazol - Google Patents

processo de preparação de amidas de ácido carboxílico pirazol

Info

Publication number
BR112012002641A2
BR112012002641A2 BR112012002641A BR112012002641A BR112012002641A2 BR 112012002641 A2 BR112012002641 A2 BR 112012002641A2 BR 112012002641 A BR112012002641 A BR 112012002641A BR 112012002641 A BR112012002641 A BR 112012002641A BR 112012002641 A2 BR112012002641 A2 BR 112012002641A2
Authority
BR
Brazil
Prior art keywords
carboxylic acid
acid amides
pyrazole carboxylic
preparing
preparing pyrazole
Prior art date
Application number
BR112012002641A
Other languages
English (en)
Other versions
BR112012002641B1 (pt
Inventor
ADRIAN MüLLER
Denis Gribkov
Fanny Giordano
Martin Lagger
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of BR112012002641A2 publication Critical patent/BR112012002641A2/pt
Publication of BR112012002641B1 publication Critical patent/BR112012002641B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/693—Unsaturated compounds containing a keto groups being part of a ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/42—One nitrogen atom
    • C07D251/44—One nitrogen atom with halogen atoms attached to the two other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
    • C07C2603/66—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

processo de preparação de amidas de ácido carboxílico pirazol. a presente invenção refere-se ao processo de preparação de (9-diclorometileno-1,2,3,4-tetra-hidro-1,4-metano-naftaleno-5-il)-amido de ácido 3-difluorometil-1-metil-1h-pirazol-4- carboxílico.
BR112012002641-0A 2009-08-06 2010-07-07 Processo de preparação de amidas de ácido carboxílico pirazol, bem como compostos intermediários BR112012002641B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09167363 2009-08-06
EP09167363.2 2009-08-06
EP09169501 2009-09-04
EP091695501.5 2009-09-04
PCT/EP2010/059703 WO2011015416A1 (en) 2009-08-06 2010-07-07 Process for the preparation of pyrazole carboxylic acid amides

Publications (2)

Publication Number Publication Date
BR112012002641A2 true BR112012002641A2 (pt) 2016-03-22
BR112012002641B1 BR112012002641B1 (pt) 2018-05-22

Family

ID=42670451

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012002641-0A BR112012002641B1 (pt) 2009-08-06 2010-07-07 Processo de preparação de amidas de ácido carboxílico pirazol, bem como compostos intermediários

Country Status (28)

Country Link
US (1) US8507694B2 (pt)
EP (1) EP2462108B1 (pt)
JP (1) JP5667186B2 (pt)
KR (1) KR101712083B1 (pt)
CN (1) CN102574779B (pt)
AR (1) AR077707A1 (pt)
AU (1) AU2010280923B2 (pt)
BR (1) BR112012002641B1 (pt)
CA (1) CA2770144C (pt)
CL (1) CL2012000272A1 (pt)
CO (1) CO6430457A2 (pt)
CR (1) CR20120056A (pt)
DK (1) DK2462108T3 (pt)
EA (1) EA019475B1 (pt)
EC (1) ECSP12011647A (pt)
EG (1) EG26957A (pt)
ES (1) ES2417315T3 (pt)
GE (1) GEP20146010B (pt)
IL (1) IL217692A (pt)
IN (1) IN2012DN00289A (pt)
MX (1) MX2012001480A (pt)
MY (1) MY161666A (pt)
NZ (1) NZ597576A (pt)
PL (1) PL2462108T3 (pt)
TW (1) TWI441812B (pt)
UY (1) UY32835A (pt)
WO (1) WO2011015416A1 (pt)
ZA (1) ZA201200413B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI534126B (zh) 2011-01-25 2016-05-21 先正達合夥公司 用於製備吡唑羧酸醯胺之方法
TWI510472B (zh) 2012-02-15 2015-12-01 Syngenta Participations Ag 立體選擇性製備吡唑羧醯胺之方法
GB201403438D0 (en) * 2014-02-27 2014-04-16 Syngenta Participations Ag Polymorphs
CA2943184C (en) 2014-03-20 2023-04-04 Mitsui Chemicals Agro, Inc. Plant disease control composition and method for controlling plant disease by application of same
WO2024017788A1 (en) 2022-07-22 2024-01-25 Syngenta Crop Protection Ag Solid form of a heterocyclic amide derivative
WO2024077487A1 (en) * 2022-10-11 2024-04-18 Syngenta Crop Protection Ag Process for the preparation of pyrazole carboxylic acid amides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370341A (en) * 1980-12-11 1983-01-25 Ayerst, Mckenna & Harrison, Ltd. 6,7,8,9-Tetrahydro-3H-benz[E]indol-8-amine derivatives
JPS58194853A (ja) * 1982-05-11 1983-11-12 Showa Denko Kk シクロヘキセン−アセチルオキシム誘導体
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
US5932752A (en) * 1995-12-29 1999-08-03 Council Of Scientific And Industrial Research Process for the C-C bond forming reaction using solid acid catalysts
GB0224316D0 (en) * 2002-10-18 2002-11-27 Syngenta Participations Ag Chemical compounds
CN1618783A (zh) * 2004-04-22 2005-05-25 复旦大学 一种多取代苯醌的制备方法
GT200600468A (es) * 2005-10-25 2007-06-08 Nuevos microbiocidas

Also Published As

Publication number Publication date
ZA201200413B (en) 2012-10-31
IN2012DN00289A (pt) 2015-05-08
EP2462108B1 (en) 2013-04-17
AU2010280923A1 (en) 2012-02-09
CN102574779B (zh) 2014-10-15
ES2417315T3 (es) 2013-08-07
AR077707A1 (es) 2011-09-14
MY161666A (en) 2017-04-28
CO6430457A2 (es) 2012-04-30
KR101712083B1 (ko) 2017-03-03
CN102574779A (zh) 2012-07-11
EG26957A (en) 2015-02-01
TWI441812B (zh) 2014-06-21
BR112012002641B1 (pt) 2018-05-22
PL2462108T3 (pl) 2013-09-30
CR20120056A (es) 2012-03-06
US20120136162A1 (en) 2012-05-31
CA2770144C (en) 2017-03-21
EP2462108A1 (en) 2012-06-13
TW201107297A (en) 2011-03-01
DK2462108T3 (da) 2013-07-08
ECSP12011647A (es) 2012-03-30
US8507694B2 (en) 2013-08-13
EA019475B1 (ru) 2014-03-31
CL2012000272A1 (es) 2012-09-28
CA2770144A1 (en) 2011-02-10
JP5667186B2 (ja) 2015-02-12
UY32835A (es) 2011-03-31
EA201200246A1 (ru) 2012-08-30
KR20120043059A (ko) 2012-05-03
WO2011015416A1 (en) 2011-02-10
AU2010280923B2 (en) 2014-08-07
GEP20146010B (en) 2014-01-10
JP2013501016A (ja) 2013-01-10
NZ597576A (en) 2013-01-25
MX2012001480A (es) 2012-02-22
IL217692A (en) 2015-07-30

Similar Documents

Publication Publication Date Title
IN2012DN02751A (pt)
BRPI0914917A2 (pt) processo para a produção de ácidos carboxílicos livres.
BR112013002925A2 (pt) processo para a síntese de ácido 2,5-furandicarboxílico
BR112014018756A8 (pt) Processo para preparo de etil éster de ácido n-(4-ciclo-hexil-3-trifluorometil-benziloxi)-acetimídico
UA111142C2 (uk) Одержання заміщених похідних 2-фторакрилової кислоти
CL2009000503A1 (es) Proceso de preparacion de compuestos derivados de acido 2-amino-5-cianobenzoico-3-sustituidos o 1h-pirazol-5-carboxamida.
BR112012002641A2 (pt) processo de preparação de amidas de ácido carboxílico pirazol
IN2014DN07129A (pt)
BR112012011961A2 (pt) processo para produzir cloretos de ácido 5-flúor-1-alquil-3-fluoralquil-1h-pirazol-4-carboxílico
MY150280A (en) Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
MX2012001411A (es) Proceso para la preparacion de derivados de acido 1-(2-halobifenil-4-il)-ciclopropanocarboxilico.
MX2015005854A (es) Metodo para producir carboxamidas.
MX2012002818A (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
MX2010005938A (es) Procedimiento para la preparacion de derivados de acido 2-fluoroacil-3-amino-acrilico.
BRPI1009635B8 (pt) ''processo de produção de cristais de ácido adípico''
WO2014087208A3 (en) A process of preparing alcaftadine
UA106195C2 (ru) Способ синтеза агомелатина
GEP20135747B (en) Method of benzonorbornenes production
MX2012000877A (es) Nuevas alcoxienonas y enaminocetonas y un procedimiento para su preparacion.
UY33879A (es) Proceso para la preparación de amidas del ácido pirazol carboxílico
FR2941959B1 (fr) Procedes de production d'acide succinique
BR112013017307A2 (pt) processo de síntese da agomelatina
MX2011012233A (es) Soluciones de retinoide topicas.
MX369283B (es) Preparacion de 2-amino-5-ciano-n, 3-dimetilbenzamida.
UA103937C2 (ru) Процесс получения амидов пиразолкарбоновой кислоты

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]