BR112016028700A2 - processo para preparação de 3,5-bis(haloalquil)pirazoles via acilação de cetiminas - Google Patents

processo para preparação de 3,5-bis(haloalquil)pirazoles via acilação de cetiminas

Info

Publication number
BR112016028700A2
BR112016028700A2 BR112016028700A BR112016028700A BR112016028700A2 BR 112016028700 A2 BR112016028700 A2 BR 112016028700A2 BR 112016028700 A BR112016028700 A BR 112016028700A BR 112016028700 A BR112016028700 A BR 112016028700A BR 112016028700 A2 BR112016028700 A2 BR 112016028700A2
Authority
BR
Brazil
Prior art keywords
haloalkyl
bis
preparing
acylation
pyrazoles
Prior art date
Application number
BR112016028700A
Other languages
English (en)
Other versions
BR112016028700B1 (pt
Inventor
Lui Norbert
Pazenok Sergii
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of BR112016028700A2 publication Critical patent/BR112016028700A2/pt
Publication of BR112016028700B1 publication Critical patent/BR112016028700B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

processo para preparação de 3,5-bis(haloalquil)pirazoles via acilação de cetiminas. a presente invenção está relacionada a um novo processo de preparação de derivados de 3,5-bis(haloalquil)pirazole via acilação de cetiminas.
BR112016028700-2A 2014-06-11 2015-06-08 Processo para preparação de 3,5-bis(haloalquil)pirazóis via acilação de cetiminas BR112016028700B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14172036.7 2014-06-11
EP14172036 2014-06-11
PCT/EP2015/062685 WO2015189138A1 (en) 2014-06-11 2015-06-08 Process for preparing 3,5-bis(haloalkyl)pyrazoles via acylation of ketimines

Publications (2)

Publication Number Publication Date
BR112016028700A2 true BR112016028700A2 (pt) 2017-08-22
BR112016028700B1 BR112016028700B1 (pt) 2021-03-23

Family

ID=50896204

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016028700-2A BR112016028700B1 (pt) 2014-06-11 2015-06-08 Processo para preparação de 3,5-bis(haloalquil)pirazóis via acilação de cetiminas

Country Status (12)

Country Link
US (1) US9914704B2 (pt)
EP (1) EP3154947B1 (pt)
JP (1) JP6514722B2 (pt)
KR (1) KR102430607B1 (pt)
CN (1) CN106458918B (pt)
BR (1) BR112016028700B1 (pt)
DK (1) DK3154947T3 (pt)
ES (1) ES2672581T3 (pt)
IL (1) IL249282B (pt)
MX (1) MX2016016399A (pt)
TW (1) TWI669292B (pt)
WO (1) WO2015189138A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10273215B2 (en) * 2015-06-26 2019-04-30 Bayer Cropscience Aktiengesellschaft Process for preparing substituted pyrazoles containing haloalkoxy- and haloalkylthio groups from alpha,alpha -dihaloalkylamines and ketimines
MX2019003255A (es) * 2016-09-21 2019-07-18 Bayer Cropscience Ag Proceso para la preparacion de 3-fluoroalquil-5-pirazolcarboxilato s y acidos 3-fluoroalquil-5-pirazolcarboxilicos.

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950790A (en) * 1988-11-14 1990-08-21 Air Products And Chemicals, Inc. Volatile fluorinated β-ketoimines and associated metal complexes
CN1390206A (zh) * 1999-09-17 2003-01-08 千嬉药品公司 因子Xa的抑制剂
DE10161978A1 (de) * 2001-12-17 2003-06-26 Bayer Ag Verfahren zur Herstellung von 2-Halogenacyl-3-amino-acrylsäure-derivate
DE10215292A1 (de) * 2002-02-19 2003-08-28 Bayer Cropscience Ag Disubstitutierte Pyrazolylcarbocanilide
DE10349500A1 (de) 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
WO2008013622A2 (en) * 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Fungicidal azocyclic amides
DE102006039909A1 (de) 2006-08-25 2008-03-13 Bayer Cropscience Ag Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten
JP2010522720A (ja) * 2007-03-28 2010-07-08 ノイロサーチ アクティーゼルスカブ プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用
EP2133341A1 (de) 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten
EP2100883A1 (de) 2008-03-10 2009-09-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4carbonsäure-Derivaten
US20090270361A1 (en) * 2008-03-26 2009-10-29 Takeda Pharmaceutical Company Limited Substituted pyrazole derivatives and use thereof
US8759527B2 (en) 2010-08-25 2014-06-24 Bayer Cropscience Ag Heteroarylpiperidine and -piperazine derivatives as fungicides
PE20140836A1 (es) * 2011-07-26 2014-08-03 Gruenenthal Chemie Derivados de carboxamida y urea que contienen pirazol heteroaromatico sustituido como ligandos del receptor de vanilloide
EP2623496A1 (de) 2012-02-01 2013-08-07 Bayer CropScience AG Verfahren zur Herstellung von 3,5-bis (fluoralkyl)-pyrazol-4-carbonsäure-Derivaten und 3,5-bis(fluoralkyl)-pyrazolen
ES2628332T3 (es) * 2012-08-07 2017-08-02 Bayer Cropscience Ag Procedimiento de preparación de pirazoles carboxilatos que contienen perfluoroalquilos
US9145370B2 (en) 2012-08-30 2015-09-29 Bayer Cropscience Ag Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives

Also Published As

Publication number Publication date
US20170114020A1 (en) 2017-04-27
MX2016016399A (es) 2017-04-06
JP2017517530A (ja) 2017-06-29
TWI669292B (zh) 2019-08-21
EP3154947B1 (en) 2018-03-28
CN106458918A (zh) 2017-02-22
TW201613869A (en) 2016-04-16
IL249282B (en) 2019-03-31
KR20170018885A (ko) 2017-02-20
WO2015189138A1 (en) 2015-12-17
IL249282A0 (en) 2017-02-28
CN106458918B (zh) 2019-07-09
JP6514722B2 (ja) 2019-05-15
DK3154947T3 (en) 2018-06-18
BR112016028700B1 (pt) 2021-03-23
ES2672581T3 (es) 2018-06-15
EP3154947A1 (en) 2017-04-19
KR102430607B1 (ko) 2022-08-08
US9914704B2 (en) 2018-03-13

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/06/2015, OBSERVADAS AS CONDICOES LEGAIS.