BR112013010551A8 - variantes de isopreno sintase para produção aprimorada de isopreno - Google Patents
variantes de isopreno sintase para produção aprimorada de isoprenoInfo
- Publication number
- BR112013010551A8 BR112013010551A8 BR112013010551A BR112013010551A BR112013010551A8 BR 112013010551 A8 BR112013010551 A8 BR 112013010551A8 BR 112013010551 A BR112013010551 A BR 112013010551A BR 112013010551 A BR112013010551 A BR 112013010551A BR 112013010551 A8 BR112013010551 A8 BR 112013010551A8
- Authority
- BR
- Brazil
- Prior art keywords
- isoprene
- enhanced
- production
- synthase variants
- isoprene synthase
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
- C12P5/005—Preparation of hydrocarbons or halogenated hydrocarbons cyclic aromatic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03027—Isoprene synthase (4.2.3.27)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
variantes de isopreno sintase para a produção aprimorada de isopreno. a presente invenção fornece métodos e composições compreendendo pelo menos uma enzima isopreno sintase com produtividade específica aprimorada. em particular, a presente invenção fornece isopreno sintases variantes de plnata para a produção aumentada de isopreno em células hospedeiras.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40741510P | 2010-10-27 | 2010-10-27 | |
PCT/US2011/058188 WO2012058494A2 (en) | 2010-10-27 | 2011-10-27 | Isoprene synthase variants for improved production of isoprene |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013010551A2 BR112013010551A2 (pt) | 2016-07-19 |
BR112013010551A8 true BR112013010551A8 (pt) | 2018-07-03 |
Family
ID=45418751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013010551A BR112013010551A8 (pt) | 2010-10-27 | 2011-10-27 | variantes de isopreno sintase para produção aprimorada de isopreno |
Country Status (8)
Country | Link |
---|---|
US (1) | US9273298B2 (pt) |
EP (1) | EP2633043A2 (pt) |
JP (1) | JP2014502148A (pt) |
CN (1) | CN103443271A (pt) |
BR (1) | BR112013010551A8 (pt) |
CA (1) | CA2816306A1 (pt) |
SG (1) | SG190043A1 (pt) |
WO (1) | WO2012058494A2 (pt) |
Families Citing this family (27)
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JP2014502844A (ja) | 2010-12-22 | 2014-02-06 | ダニスコ・ユーエス・インク | 組み換え細胞による五炭糖の生物学的生産 |
CN103930541A (zh) | 2011-04-29 | 2014-07-16 | 丹尼斯科美国公司 | 用于增强甲羟戊酸、异戊二烯和类异戊二烯的产量的重组微生物 |
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SG11201401249PA (en) | 2011-10-07 | 2014-05-29 | Danisco Us Inc | Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene |
BR112014010053A8 (pt) | 2011-10-27 | 2017-06-20 | Danisco Us Inc | variantes de isopreno sintase com solubilidade aprimorada para produção de isopreno |
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CN104919038A (zh) * | 2012-10-23 | 2015-09-16 | 积水化学工业株式会社 | 重组细胞以及异戊二烯的生产方法 |
US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
SG11201508186XA (en) | 2013-04-10 | 2015-11-27 | Danisco Us Inc | Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids |
EP3072967B1 (en) | 2013-11-22 | 2020-01-01 | Ajinomoto Co., Inc. | Modified isoprene synthase |
US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
CN104531855A (zh) * | 2014-12-18 | 2015-04-22 | 宁波检验检疫科学技术研究院 | 一种细菌ⅰ型整合子的荧光定量pcr检测试剂 |
CN105985972A (zh) * | 2015-02-10 | 2016-10-05 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
CN105985973A (zh) * | 2015-02-10 | 2016-10-05 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
CN105985976A (zh) * | 2015-02-10 | 2016-10-05 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
CN105985977B (zh) * | 2015-02-10 | 2020-12-25 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
CN105985975A (zh) * | 2015-02-10 | 2016-10-05 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
CN105985974A (zh) * | 2015-02-10 | 2016-10-05 | 中国科学院微生物研究所 | 异戊二烯合成酶基因及其应用 |
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-
2011
- 2011-10-27 CN CN2011800628994A patent/CN103443271A/zh active Pending
- 2011-10-27 CA CA2816306A patent/CA2816306A1/en not_active Abandoned
- 2011-10-27 BR BR112013010551A patent/BR112013010551A8/pt not_active IP Right Cessation
- 2011-10-27 EP EP11802178.1A patent/EP2633043A2/en not_active Withdrawn
- 2011-10-27 JP JP2013536854A patent/JP2014502148A/ja active Pending
- 2011-10-27 SG SG2013032479A patent/SG190043A1/en unknown
- 2011-10-27 WO PCT/US2011/058188 patent/WO2012058494A2/en active Application Filing
- 2011-10-27 US US13/283,564 patent/US9273298B2/en not_active Expired - Fee Related
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WO2012058494A2 (en) | 2012-05-03 |
JP2014502148A (ja) | 2014-01-30 |
US9273298B2 (en) | 2016-03-01 |
BR112013010551A2 (pt) | 2016-07-19 |
EP2633043A2 (en) | 2013-09-04 |
SG190043A1 (en) | 2013-06-28 |
CN103443271A (zh) | 2013-12-11 |
WO2012058494A3 (en) | 2012-09-20 |
CA2816306A1 (en) | 2012-05-03 |
US20130045891A1 (en) | 2013-02-21 |
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