BR112013010551A8 - variantes de isopreno sintase para produção aprimorada de isopreno - Google Patents

variantes de isopreno sintase para produção aprimorada de isopreno

Info

Publication number
BR112013010551A8
BR112013010551A8 BR112013010551A BR112013010551A BR112013010551A8 BR 112013010551 A8 BR112013010551 A8 BR 112013010551A8 BR 112013010551 A BR112013010551 A BR 112013010551A BR 112013010551 A BR112013010551 A BR 112013010551A BR 112013010551 A8 BR112013010551 A8 BR 112013010551A8
Authority
BR
Brazil
Prior art keywords
isoprene
enhanced
production
synthase variants
isoprene synthase
Prior art date
Application number
BR112013010551A
Other languages
English (en)
Other versions
BR112013010551A2 (pt
Inventor
Lee Rife Christopher
A Estell David
H Wells Derek
V Miller Jeffrey
Q Beck Zachary
Original Assignee
Danisco Us Inc
Goodyear Tire & Rubber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc, Goodyear Tire & Rubber filed Critical Danisco Us Inc
Publication of BR112013010551A2 publication Critical patent/BR112013010551A2/pt
Publication of BR112013010551A8 publication Critical patent/BR112013010551A8/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
    • C12P5/005—Preparation of hydrocarbons or halogenated hydrocarbons cyclic aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027—Isoprene synthase (4.2.3.27)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

variantes de isopreno sintase para a produção aprimorada de isopreno. a presente invenção fornece métodos e composições compreendendo pelo menos uma enzima isopreno sintase com produtividade específica aprimorada. em particular, a presente invenção fornece isopreno sintases variantes de plnata para a produção aumentada de isopreno em células hospedeiras.
BR112013010551A 2010-10-27 2011-10-27 variantes de isopreno sintase para produção aprimorada de isopreno BR112013010551A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40741510P 2010-10-27 2010-10-27
PCT/US2011/058188 WO2012058494A2 (en) 2010-10-27 2011-10-27 Isoprene synthase variants for improved production of isoprene

Publications (2)

Publication Number Publication Date
BR112013010551A2 BR112013010551A2 (pt) 2016-07-19
BR112013010551A8 true BR112013010551A8 (pt) 2018-07-03

Family

ID=45418751

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013010551A BR112013010551A8 (pt) 2010-10-27 2011-10-27 variantes de isopreno sintase para produção aprimorada de isopreno

Country Status (8)

Country Link
US (1) US9273298B2 (pt)
EP (1) EP2633043A2 (pt)
JP (1) JP2014502148A (pt)
CN (1) CN103443271A (pt)
BR (1) BR112013010551A8 (pt)
CA (1) CA2816306A1 (pt)
SG (1) SG190043A1 (pt)
WO (1) WO2012058494A2 (pt)

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BR112013018316A2 (pt) 2010-12-22 2018-09-11 Danisco Us Inc composições e métodos para produção aprimorada de isopreno usando dois tipos de enzimas ispg
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AU2012249320A1 (en) 2011-04-29 2013-11-14 Danisco Us Inc. Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids
BR112014002661A2 (pt) 2011-08-04 2019-09-24 Danisco Us Inc produção de isopreno, precursores de isoprenoide, e isoprenoides com o uso de acetoacetil-coa sintase
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US9951363B2 (en) 2014-03-14 2018-04-24 The Research Foundation for the State University of New York College of Environmental Science and Forestry Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects
CN104531855A (zh) * 2014-12-18 2015-04-22 宁波检验检疫科学技术研究院 一种细菌ⅰ型整合子的荧光定量pcr检测试剂
CN105985972A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985977B (zh) * 2015-02-10 2020-12-25 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985973A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985974A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985976A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
CN105985975A (zh) * 2015-02-10 2016-10-05 中国科学院微生物研究所 异戊二烯合成酶基因及其应用
US20210161092A1 (en) * 2016-02-16 2021-06-03 Ajikumar Parayil KUMARAN Secondary metabolite screening system
CN107365758B (zh) * 2016-05-12 2021-03-05 山东常青藤生物科技有限公司 五碳平台化合物合成基因及其应用

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EP2633043A2 (en) 2013-09-04
BR112013010551A2 (pt) 2016-07-19
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US9273298B2 (en) 2016-03-01
WO2012058494A2 (en) 2012-05-03
CN103443271A (zh) 2013-12-11
SG190043A1 (en) 2013-06-28
US20130045891A1 (en) 2013-02-21
JP2014502148A (ja) 2014-01-30

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