IN2015KN00073A - - Google Patents

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Publication number
IN2015KN00073A
IN2015KN00073A IN73KON2015A IN2015KN00073A IN 2015KN00073 A IN2015KN00073 A IN 2015KN00073A IN 73KON2015 A IN73KON2015 A IN 73KON2015A IN 2015KN00073 A IN2015KN00073 A IN 2015KN00073A
Authority
IN
India
Prior art keywords
relates
present
rna molecule
individual cells
molecule expressed
Prior art date
Application number
Other languages
English (en)
Inventor
Yuri Bushkin
Maria Laura Gennaro
Sanjay Tyagi
Richard Pine
Original Assignee
Univ Rutgers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers filed Critical Univ Rutgers
Publication of IN2015KN00073A publication Critical patent/IN2015KN00073A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866Interferon
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
IN73KON2015 2012-06-27 2013-06-26 IN2015KN00073A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261665231P 2012-06-27 2012-06-27
US201361784802P 2013-03-14 2013-03-14
PCT/US2013/047774 WO2014004609A2 (en) 2012-06-27 2013-06-26 Rapid assays for t-cell activation by rna measurements using flow cytometry

Publications (1)

Publication Number Publication Date
IN2015KN00073A true IN2015KN00073A (pt) 2015-07-31

Family

ID=49784002

Family Applications (1)

Application Number Title Priority Date Filing Date
IN73KON2015 IN2015KN00073A (pt) 2012-06-27 2013-06-26

Country Status (12)

Country Link
US (2) US10900072B2 (pt)
EP (2) EP3828278A1 (pt)
JP (1) JP6464081B2 (pt)
KR (1) KR20150036186A (pt)
CN (2) CN108624654A (pt)
AU (2) AU2013280416B2 (pt)
BR (1) BR112014032677A2 (pt)
CA (1) CA2877933A1 (pt)
IN (1) IN2015KN00073A (pt)
RU (1) RU2671707C2 (pt)
WO (1) WO2014004609A2 (pt)
ZA (1) ZA201500239B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107326085B (zh) 2012-02-03 2022-05-03 加州理工学院 多路生化测定中信号的编码和解码
CN106198358B (zh) * 2016-06-24 2019-02-15 北京大学 基于"石英杯中激发型"流式细胞分选仪的染色体分选方法
CN108732082A (zh) * 2018-06-07 2018-11-02 北京唯公医疗技术有限公司 细胞分群方法
WO2021046121A1 (en) * 2019-09-03 2021-03-11 The Regents Of The University Of California Method to sequence mrna in single cells in parallel with quantification of intracellular phenotype
JP2023500456A (ja) * 2019-10-29 2023-01-06 ウニベルジテート ハイデルベルク 人工抗原提示分子とその利用
CN111999235A (zh) * 2020-07-03 2020-11-27 青岛农业大学 一种利用流式细胞术快速检测有活力的食用菌原生质体数量的方法
RU2766781C1 (ru) * 2021-03-03 2022-03-15 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) Способ выявления поражения сосудистого эндотелия
WO2022271272A1 (en) * 2021-06-22 2022-12-29 Nantcell, Inc. Rapid test for patient cd8 t-cell activation, systems and methods

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US4994369A (en) * 1987-12-15 1991-02-19 The Board Of Trustees Of The Leland Stanford Jr. Univ. T-cell activation related gene
US5866331A (en) 1995-10-20 1999-02-02 University Of Massachusetts Single molecule detection by in situ hybridization
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
DE69739497D1 (de) * 1996-10-01 2009-08-27 Geron Corp Menschlische Telomerase katalytische Untereinheit
US7514232B2 (en) 1996-12-06 2009-04-07 Becton, Dickinson And Company Method for detecting T cell response to specific antigens in whole blood
JP4405686B2 (ja) 1999-03-09 2010-01-27 ザイモジェネティクス,インコーポレイティド 新規サイトカインzalpha11リガンド
RU2258710C2 (ru) 1999-03-09 2005-08-20 Займодженетикс, Инк. Новый цитокин zalpha11-лиганд
WO2009003492A1 (en) 2007-07-03 2009-01-08 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
EP1502109A4 (en) 2002-04-19 2007-01-10 Scripps Research Inst COMPOSITIONS AND METHODS RELATING TO THE SIGNALING OF ENDOTHELIAL CELLS USING THE PROTEASE-ACTIVATED RECEPTOR (PAR1)
CN100567987C (zh) * 2002-08-08 2009-12-09 贝勒医学院 T细胞疫苗及其制备方法
WO2005118788A2 (en) * 2004-05-27 2005-12-15 The Trustees Of The University Of Pennsylvania Novel artificial antigen presenting cells and uses therefor
DE102005020754B3 (de) 2005-05-02 2007-01-11 Altana Pharma Ag Zelluläres Assayverfahren zur Identifizierung von PKCtheta-Inhibitoren
CN101495650B (zh) 2005-06-20 2015-02-04 领先细胞医疗诊断有限公司 检测单个细胞中的核酸和鉴定异质大细胞群中罕见细胞的方法
US20090081688A1 (en) 2005-06-20 2009-03-26 Advanced Cell Diagnostics Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations
EP1760089B1 (en) 2005-09-05 2009-08-19 Immatics Biotechnologies GmbH Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine
WO2008069940A2 (en) * 2006-12-06 2008-06-12 Albert Einstein College Of Medicine Of Yeshiva University Multi-microrna methods and compositions
JP2010004750A (ja) * 2008-06-24 2010-01-14 Institute For Rheumatic Diseases Co Ltd 自己免疫疾患による組織傷害の発症または発症可能性の診断方法、およびその利用
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JP5344007B2 (ja) * 2011-06-30 2013-11-20 株式会社デンソー 近距離無線通信装置

Also Published As

Publication number Publication date
WO2014004609A3 (en) 2014-02-27
CN104662170A (zh) 2015-05-27
AU2013280416B2 (en) 2017-06-15
JP6464081B2 (ja) 2019-02-06
US10900072B2 (en) 2021-01-26
WO2014004609A2 (en) 2014-01-03
JP2015522284A (ja) 2015-08-06
US11767551B2 (en) 2023-09-26
AU2017228677A1 (en) 2017-10-05
EP2867374A4 (en) 2016-05-11
US20210139965A1 (en) 2021-05-13
RU2671707C2 (ru) 2018-11-06
AU2017228677B2 (en) 2019-02-14
CA2877933A1 (en) 2014-01-03
CN108624654A (zh) 2018-10-09
EP3828278A1 (en) 2021-06-02
BR112014032677A2 (pt) 2019-01-15
KR20150036186A (ko) 2015-04-07
EP2867374B1 (en) 2020-10-28
US20160201122A1 (en) 2016-07-14
AU2013280416A1 (en) 2015-02-05
EP2867374A2 (en) 2015-05-06
RU2015102447A (ru) 2016-08-20
ZA201500239B (en) 2015-12-23

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