BR112013000675A2 - nanopartícula, processo para produzir uma nanopartícula compreendendo uma matriz de zeína e um aminoácido básico, processo para produzir uma nanopartícula compreendendo uma matriz de zeína, e um aminoácido básico e um composto biologicamente ativo solúvel em gordura, composição e produto alimentar - Google Patents

nanopartícula, processo para produzir uma nanopartícula compreendendo uma matriz de zeína e um aminoácido básico, processo para produzir uma nanopartícula compreendendo uma matriz de zeína, e um aminoácido básico e um composto biologicamente ativo solúvel em gordura, composição e produto alimentar

Info

Publication number
BR112013000675A2
BR112013000675A2 BR112013000675A BR112013000675A BR112013000675A2 BR 112013000675 A2 BR112013000675 A2 BR 112013000675A2 BR 112013000675 A BR112013000675 A BR 112013000675A BR 112013000675 A BR112013000675 A BR 112013000675A BR 112013000675 A2 BR112013000675 A2 BR 112013000675A2
Authority
BR
Brazil
Prior art keywords
nanoparticle
amino acid
basic amino
producing
zein matrix
Prior art date
Application number
BR112013000675A
Other languages
English (en)
Other versions
BR112013000675B1 (pt
Inventor
Ana Romo Hualde
Carlos Javier González Navarro
Carolina González Ferrero
Irene Esparza Catalán
Juan Manuel Irache Garreta
Maite Agüeros Bazo
Original Assignee
Ct Nac De Tecnología Y Seguridad Alimentaria Lab D
Univ Navarra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Nac De Tecnología Y Seguridad Alimentaria Lab D, Univ Navarra filed Critical Ct Nac De Tecnología Y Seguridad Alimentaria Lab D
Publication of BR112013000675A2 publication Critical patent/BR112013000675A2/pt
Publication of BR112013000675B1 publication Critical patent/BR112013000675B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S264/00—Plastic and nonmetallic article shaping or treating: processes
    • Y10S264/59—Processes in which a partial cure is involved

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

nanopartícula, processo para produzir uma nanopartícula compreendendo uma matriz de zeína e um aminoácido básico, processo para produzir uma nanopartícula compreendendo uma matriz de zeína, um aminoácido básico e um composto biologicamente ativo solúvel em gordura, composição e produto alimentar. a presente invenção se refere às nanopartículas para a encapsulação de compostos, à obtenção e ao uso destas. as nanopartículas compreendem uma matriz de zeína e um aminoácido básico. as refereidas nanopartículas podem encapsular um composto biologicamente ativo solúvel em gordura ou solúvel em água. isso é aplicável no setor de cosméticos, farmacêutico e alimentar e no setor da nanotecnologia.
BR112013000675-7A 2010-07-16 2011-07-15 Nanopartícula, processo para produzir uma nanopartícula compreendendo uma matriz de zeína e um aminoácido básico, composição e produto alimentar BR112013000675B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES201031095 2010-07-16
ESP201031095 2010-07-16
PCT/ES2011/070518 WO2012007628A1 (es) 2010-07-16 2011-07-15 Nanopartículas para encapsulación de compuestos, su obtención y usos

Publications (2)

Publication Number Publication Date
BR112013000675A2 true BR112013000675A2 (pt) 2016-05-31
BR112013000675B1 BR112013000675B1 (pt) 2021-07-20

Family

ID=44764176

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013000675-7A BR112013000675B1 (pt) 2010-07-16 2011-07-15 Nanopartícula, processo para produzir uma nanopartícula compreendendo uma matriz de zeína e um aminoácido básico, composição e produto alimentar

Country Status (14)

Country Link
US (1) US9381252B2 (pt)
EP (1) EP2594140B1 (pt)
JP (1) JP6046615B2 (pt)
KR (1) KR101933024B1 (pt)
CN (1) CN103037707B (pt)
AU (1) AU2011278186B2 (pt)
BR (1) BR112013000675B1 (pt)
CA (1) CA2805581C (pt)
DK (1) DK2594140T3 (pt)
ES (1) ES2724176T3 (pt)
MX (1) MX338891B (pt)
PL (1) PL2594140T3 (pt)
PT (1) PT2594140T (pt)
WO (1) WO2012007628A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2625966A1 (en) * 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
JP6235779B2 (ja) * 2012-03-28 2017-11-22 株式会社コーセー 葉酸含有組成物及び葉酸の安定化方法
KR101362800B1 (ko) * 2012-10-16 2014-02-14 한국식품연구원 피토스테롤이 함유된 프롤라민-양이온 폴리머 복합체 및 이의 제조방법
GB201312245D0 (en) * 2013-07-08 2013-08-21 Gorman Eddie O An extrusion process
EP2856987A1 (en) 2013-10-07 2015-04-08 Absorbest AB A wound dressing and a method for manufacturing a wound dressing
WO2016025394A2 (en) 2014-08-11 2016-02-18 Board Of Supervisors Of Louisiana State University And Agriculatural And Mechanical College Delivery of bioactive, nanoencapsulated antioxidants
MX2017013557A (es) 2015-04-22 2018-02-26 Basf Se Nanoparticulas, nanoemulsiones y su formacion con micronizacion en camara de mezcla.
CN108308615A (zh) * 2018-01-12 2018-07-24 齐齐哈尔大学 一种玉米肽为载体的叶黄素纳米粒的制备方法
CN108576501B (zh) * 2018-01-18 2021-07-02 广东药科大学 一种植物多酚类功能饮料的制备方法
EP3581176A1 (en) 2018-06-12 2019-12-18 Universidad de Navarra Core-shell zein nanoparticles for the encapsulation of compounds, process for their preparation and uses thereof
CN112535212A (zh) * 2019-09-20 2021-03-23 内蒙古伊利实业集团股份有限公司 儿茶素原料的预处理方法以及包含儿茶素的果汁牛奶
CN111893584B (zh) * 2020-06-16 2021-06-22 杭州千芝雅卫生用品有限公司 耐水性环保纤维滤材及其制备方法
CN112370419A (zh) * 2020-10-16 2021-02-19 江苏大学 一种醇溶性蛋白、氨基酸或/和多糖协同稳定的Pickering乳液凝胶的制备方法
WO2022136393A1 (en) 2020-12-23 2022-06-30 Universidad De Navarra Zein nanoparticles for use in hyperglycemic conditions
CN113244193A (zh) * 2021-04-26 2021-08-13 南京大学 用于递送甾醇及其衍生物的蛋白纳米粒的制法与应用
CN114129538B (zh) * 2021-10-26 2022-12-09 浙江科技学院 一种负载藏红花素玉米醇溶蛋白纳米颗粒的制备方法及应用
WO2023086572A2 (en) * 2021-11-12 2023-05-19 Tolan Naomie Lucas Combinations of nanoparticle-encapsulated cargo entities and methods for making and using same
WO2023154838A2 (en) * 2022-02-11 2023-08-17 Arizona Board Of Regents On Behalf Of Arizona State University Antimicrobial materials and nanoparticles and methods of use thereof
US11559495B1 (en) * 2022-03-07 2023-01-24 King Abdulaziz University Icariin nano-pharmaceutical formulation
CN114796155B (zh) * 2022-03-31 2023-06-27 诺丁汉大学卓越灯塔计划(宁波)创新研究院 天然活性物质-玉米蛋白纳米颗粒及其制备方法和用途
CN116172115B (zh) * 2022-12-05 2024-05-14 西北农林科技大学 通过添加L-Lys改善高剂量EGCG对肉蛋白凝胶特性损伤的方法
CN116333079B (zh) * 2023-03-07 2023-09-15 中国农业科学院农产品加工研究所 一种用叶酸修饰的玉米醇溶蛋白及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0550436A1 (en) * 1989-11-06 1993-07-14 Alkermes Controlled Therapeutics, Inc. Protein microspheres and methods of using them
JP3790567B2 (ja) * 1994-09-30 2006-06-28 武田薬品工業株式会社 徐放剤
FR2824756B1 (fr) 2001-05-16 2005-07-08 Mainelab Microcapsules a base de proteines vegetales
US20040086595A1 (en) 2002-10-31 2004-05-06 Jingping Liu Plasticized prolamine compositions
CN1717180A (zh) * 2002-11-29 2006-01-04 服洛因得产业股份有限公司 水性虫胶包膜材料、其制造方法、使用该包膜材料的包膜食品、其制造方法、包膜医药品、其制造方法、油性糖果的着色用组合物、着色方法、及着色油性糖果
JP2004269384A (ja) * 2003-03-06 2004-09-30 Kyowa Hakko Kogyo Co Ltd 吸水性アミノ酸被覆顆粒
CN1476825A (zh) * 2003-07-04 2004-02-25 中国科学院上海有机化学研究所 谷物类醇溶蛋白微球和制备方法
CA2548992A1 (en) 2003-12-11 2005-08-11 Vaxdesign Corporation Immunotherapy compositions, method of making and method of use thereof
CN1562373A (zh) * 2004-03-25 2005-01-12 上海交通大学 植物源性醇溶蛋白微球固体剂型的制备方法
MX2008003213A (es) 2005-09-09 2008-03-18 Kellog Co Acidos grasos omega-3 encapsulados en recubrimientos de zeina y productos alimenticios que los incorporan.
ES2564241T3 (es) * 2005-12-02 2016-03-21 Glaxosmithkline Biologicals Sa Nanopartículas para su uso en composiciones inmunogénicas
US20080305096A1 (en) 2007-06-07 2008-12-11 Unicity International, Inc. Method and composition for providing controlled delivery of biologically active substances
TWI437962B (zh) * 2007-06-19 2014-05-21 Dsm Ip Assets Bv 微包封組成物、其製造方法、使用方法及其產物
CN201092514Y (zh) 2007-06-25 2008-07-30 上海港机重工有限公司 双起升式集装箱起重机运行小车的吊具上架限位装置
CN100540608C (zh) * 2007-07-20 2009-09-16 浙江大学 谷类蛋白质/纳米粒子原位复合材料及其制备方法
EP2214747A2 (en) 2007-11-20 2010-08-11 Cook Incorporated Controlled drug delivery using a zein layer modified with levulinic acid
CN101485629B (zh) 2008-01-16 2013-01-23 沈阳药科大学 一种给药系统及其制备方法
KR101616771B1 (ko) * 2008-05-09 2016-04-29 사우스다코타주립대학 비면역원성의 소수성 단백질 나노입자의 형성방법 및 그 용도

Also Published As

Publication number Publication date
CN103037707A (zh) 2013-04-10
JP6046615B2 (ja) 2016-12-21
MX2013000636A (es) 2013-05-31
EP2594140B1 (en) 2019-03-20
KR101933024B1 (ko) 2018-12-27
KR20130045358A (ko) 2013-05-03
CN103037707B (zh) 2016-08-31
AU2011278186B2 (en) 2015-02-05
DK2594140T3 (da) 2019-06-03
US9381252B2 (en) 2016-07-05
BR112013000675B1 (pt) 2021-07-20
US20130116261A1 (en) 2013-05-09
PL2594140T3 (pl) 2019-09-30
AU2011278186A1 (en) 2013-01-31
MX338891B (es) 2016-05-04
ES2724176T3 (es) 2019-09-06
PT2594140T (pt) 2019-06-11
CA2805581A1 (en) 2012-01-19
JP2013532630A (ja) 2013-08-19
CA2805581C (en) 2018-10-02
WO2012007628A1 (es) 2012-01-19
EP2594140A1 (en) 2013-05-22
RU2013106946A (ru) 2014-08-27

Similar Documents

Publication Publication Date Title
BR112013000675A2 (pt) nanopartícula, processo para produzir uma nanopartícula compreendendo uma matriz de zeína e um aminoácido básico, processo para produzir uma nanopartícula compreendendo uma matriz de zeína, e um aminoácido básico e um composto biologicamente ativo solúvel em gordura, composição e produto alimentar
BR112012021372A2 (pt) nanopartícula, processo para produção de nanopartículas, composição e gênero alimentício
BR112015000041A2 (pt) micropartícula, método para a obtenção das micropartículas definidas, composição, produto alimentar, farmacêutico, cosmecêutico ou nutracêutico e uso de uma micropartícula
BR112014002757A2 (pt) encapsulados
CO6531471A2 (es) Cápsulas resistentes a ácido
WO2012104275A3 (en) Nanoparticles delivery systems, preparation and uses thereof
BR112015011112A2 (pt) composto oligomérico, oligômero, composição farmacêutica, uso do composto oligomérico, método de síntese de um composto oligomérico e método de tratamento de uma doença.
BR112014029247A2 (pt) nanopartícula de lipídio, composição farmacêutica, método para fazer uma nanopartícula de lipído, produto, método de tratamento de um distúrbio, e sistema de entrega
CL2013001282A1 (es) Sal succinato de dimetil-amida del acido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]-pirimidin-6-carboxilico; composicion farmaceutica que la comprende y procesos para su preparacion.
GT201200250A (es) Ariltriazolonas ligadas a bisarilo y su uso
BR112012017737A8 (pt) polivinilpirrolidona para a estabilização de uma dispersão sólida da forma não cristalina de rotigotina.
BR112014013175A8 (pt) composições de liberação prolongada baseadas em lipídios anfipáticos e processo para preparar comprimidos de composição de liberação prolongada
BRPI0905733A2 (pt) "composição, formulação farmacêutica, método para tratamento de câncer positivo para her2 e método pára a produção de uma composição farmacêutica"
BR112015012547A2 (pt) composições de prostaciclina e métodos de sua utilização
BRPI0816320A2 (pt) Composto, formulação farmacêutica, uso de um composto, método de tratamento de uma doença, produto de combinação, e, processos para a preparação deu um composto, de uma formulação farmacêutica, e de um produto de combinação
CY1115595T1 (el) Αλατα ρασιγιλινης και φαρμακευτικη παρασκευη αυτων
MX2011013726A (es) Nanodispersión de un medicamento y proceso para su preparación.
BR112013002710A2 (pt) nanocompósito de polímero compreendendo ácido poliláctico reforçado com o filossilicato modificado
BR112012015977A2 (pt) composto derivado de poli (ácido lático), método para preparar o composto derivado de poli (ácido lático), complexo do composto de derivado de poli (ácido lático), composição de liberação prolongada de droga, e, método para preparar a composição de liberação prolongada de droga
BR112013024824A2 (pt) ésteres isopentílicos para uso em composições cosméticas, dermatológicas ou farmacêuticas
IL227024A (en) The 3 heteroarylamino propionic acid derivatives are converted into amino acids, a process for their preparation, their use in the preparation of medicinal preparations and as medical preparations containing them
EP2799438A4 (en) FAT-SOLUBLE ANTICANCER DRUG COMPOUND, MODIFIED BY A WATER-SOLUBLE VITAMIN E DERIVATIVE, AND FORMULATION, PREPARATION METHOD AND USE THEREOF
BR112012030485A2 (pt) composição para prevenção ou tratamento de osteoporose e processo de fabricação para a mesma
BR112014009242A8 (pt) nanossuspensão farmacêutica
BR112014014021A2 (pt) composição cosmética, produto para o tratamento da transpiração e processo para a produção de uma composição cosmética

Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: UNIVERSIDAD DE NAVARRA (ES) , CENTRO NACIONAL DE T

B15K Others concerning applications: alteration of classification

Ipc: A61K 47/42 (2017.01), A23P 10/30 (2016.01), A61K 8

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/07/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.