BR112012028524B1 - Composições farmacêuticas e respectivos usos, métodos de preparação e kit - Google Patents

Composições farmacêuticas e respectivos usos, métodos de preparação e kit Download PDF

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Publication number
BR112012028524B1
BR112012028524B1 BR112012028524-6A BR112012028524A BR112012028524B1 BR 112012028524 B1 BR112012028524 B1 BR 112012028524B1 BR 112012028524 A BR112012028524 A BR 112012028524A BR 112012028524 B1 BR112012028524 B1 BR 112012028524B1
Authority
BR
Brazil
Prior art keywords
solution
molar ratio
less
minocycline
tigecycline
Prior art date
Application number
BR112012028524-6A
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English (en)
Portuguese (pt)
Other versions
BR112012028524A2 (pt
Inventor
David C. Griffith
Serge Boyer
Original Assignee
Rempex Pharmaceuticals, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44914987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012028524(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rempex Pharmaceuticals, Inc filed Critical Rempex Pharmaceuticals, Inc
Publication of BR112012028524A2 publication Critical patent/BR112012028524A2/pt
Publication of BR112012028524B1 publication Critical patent/BR112012028524B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR112012028524-6A 2010-05-12 2011-05-12 Composições farmacêuticas e respectivos usos, métodos de preparação e kit BR112012028524B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33410610P 2010-05-12 2010-05-12
US61/334,106 2010-05-12
US39230410P 2010-10-12 2010-10-12
US61/392,304 2010-10-12
PCT/US2011/036351 WO2011143503A2 (en) 2010-05-12 2011-05-12 Tetracycline compositions

Publications (2)

Publication Number Publication Date
BR112012028524A2 BR112012028524A2 (pt) 2016-07-19
BR112012028524B1 true BR112012028524B1 (pt) 2022-03-15

Family

ID=44914987

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012028524-6A BR112012028524B1 (pt) 2010-05-12 2011-05-12 Composições farmacêuticas e respectivos usos, métodos de preparação e kit

Country Status (21)

Country Link
US (7) US9278105B2 (https=)
EP (2) EP3135289B1 (https=)
JP (2) JP6025712B2 (https=)
KR (1) KR101799304B1 (https=)
CN (1) CN102970992B (https=)
AU (1) AU2011252919B2 (https=)
BR (1) BR112012028524B1 (https=)
CA (1) CA2799079C (https=)
CL (1) CL2012003168A1 (https=)
CO (1) CO6650346A2 (https=)
DK (1) DK2568987T3 (https=)
ES (2) ES2715551T3 (https=)
HU (1) HUE033161T2 (https=)
IL (1) IL222896A (https=)
MX (1) MX347919B (https=)
PL (1) PL2568987T3 (https=)
PT (1) PT2568987T (https=)
RU (1) RU2647972C2 (https=)
SG (1) SG185513A1 (https=)
WO (1) WO2011143503A2 (https=)
ZA (1) ZA201208466B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101799304B1 (ko) 2010-05-12 2017-11-20 렘펙스 파머수티클스 인코퍼레이티드 테트라사이클린 조성물
CN102697739B (zh) * 2012-05-31 2014-10-29 丽珠医药集团股份有限公司 一种减少替加环素差向异构体化的粉针剂制备方法
IN2013MU01127A (https=) * 2013-03-26 2015-05-01 Astron Res Ltd
WO2014167575A2 (en) 2013-03-26 2014-10-16 Astron Research Limited Stable tigecycline composition
US20140323443A1 (en) * 2013-04-30 2014-10-30 Fresenius Kabi Usa, Llc Tigecycline formulations
KR20170134514A (ko) 2015-03-23 2017-12-06 바이오팜엑스 인코포레이티드 피부과 사용을 위한 약학 테트라사이클린 조성물
PT108978B (pt) * 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
BR112021007969A2 (pt) 2018-10-29 2021-07-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. complexos de tetraciclina com atividade controlada
GB201904851D0 (en) 2019-04-05 2019-05-22 Katholieke Univ Leven Melanoma treatment
WO2021063468A1 (en) * 2019-10-02 2021-04-08 Anfarm Hellas S.A. Stable parenteral pharmaceutical composition containing tigecycline and process for the preparation thereof
CN113101371A (zh) * 2021-04-07 2021-07-13 中国科学院大学温州研究院(温州生物材料与工程研究所) 一种基于阳离子-π作用的疏水药物的增溶方法
CN119157870A (zh) * 2024-10-08 2024-12-20 宁夏大学 铜盐在制备缓解替加环素光解作用药物中的医药用途

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Publication number Publication date
RU2647972C2 (ru) 2018-03-21
US20130040918A1 (en) 2013-02-14
KR101799304B1 (ko) 2017-11-20
CN102970992B (zh) 2016-07-06
ZA201208466B (en) 2018-12-19
ES2715551T3 (es) 2019-06-04
SG185513A1 (en) 2012-12-28
US9744179B2 (en) 2017-08-29
US20140194393A1 (en) 2014-07-10
KR20130080797A (ko) 2013-07-15
AU2011252919B2 (en) 2017-01-19
US9278105B2 (en) 2016-03-08
US20150094282A1 (en) 2015-04-02
PT2568987T (pt) 2017-02-03
WO2011143503A3 (en) 2012-01-19
AU2011252919A1 (en) 2012-12-06
BR112012028524A2 (pt) 2016-07-19
CN102970992A (zh) 2013-03-13
DK2568987T3 (en) 2017-02-20
ES2613738T3 (es) 2017-05-25
EP2568987A4 (en) 2014-05-21
US9084802B2 (en) 2015-07-21
JP6025712B2 (ja) 2016-11-16
HUE033161T2 (en) 2017-11-28
US12161656B2 (en) 2024-12-10
US20180078570A1 (en) 2018-03-22
CA2799079C (en) 2019-01-15
US20250049820A1 (en) 2025-02-13
EP2568987B1 (en) 2016-11-16
IL222896A0 (en) 2012-12-31
WO2011143503A2 (en) 2011-11-17
CO6650346A2 (es) 2013-04-15
CL2012003168A1 (es) 2013-12-20
EP2568987A2 (en) 2013-03-20
EP3135289A1 (en) 2017-03-01
MX347919B (es) 2017-05-17
HK1180586A1 (zh) 2013-10-25
US11944634B2 (en) 2024-04-02
EP3135289B1 (en) 2018-12-12
MX2012012993A (es) 2013-08-27
US20240189326A1 (en) 2024-06-13
JP2016145253A (ja) 2016-08-12
AU2011252919A2 (en) 2012-12-06
JP6290298B2 (ja) 2018-03-07
JP2013529201A (ja) 2013-07-18
PL2568987T3 (pl) 2017-06-30
IL222896A (en) 2017-03-30
CA2799079A1 (en) 2011-11-17
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US20200000828A1 (en) 2020-01-02

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