BR112012027416A8 - métodos e dispositivos para distribuição de droga a tecido ocular utilizando microagulha - Google Patents

métodos e dispositivos para distribuição de droga a tecido ocular utilizando microagulha

Info

Publication number
BR112012027416A8
BR112012027416A8 BR112012027416A BR112012027416A BR112012027416A8 BR 112012027416 A8 BR112012027416 A8 BR 112012027416A8 BR 112012027416 A BR112012027416 A BR 112012027416A BR 112012027416 A BR112012027416 A BR 112012027416A BR 112012027416 A8 BR112012027416 A8 BR 112012027416A8
Authority
BR
Brazil
Prior art keywords
microneedle
methods
devices
eye
drug delivery
Prior art date
Application number
BR112012027416A
Other languages
English (en)
Other versions
BR112012027416A2 (pt
Inventor
F Edelhauser Henry
R Prausnitz Mark
Rajnikant Patel Samirkumar
Original Assignee
Univ Emory
Georgia Tech Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Emory, Georgia Tech Res Inst filed Critical Univ Emory
Publication of BR112012027416A2 publication Critical patent/BR112012027416A2/pt
Publication of BR112012027416A8 publication Critical patent/BR112012027416A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

métodos e dispositivos para distribuição de droga a tecido ocular utilizando microagulha. métodos e dispositivos são fornecidos para administração direcionada de uma droga ao olho de um paciente. em uma modalidade, o método inclui inserir uma microagulha oca na esclera do olho em um sítio de inserção e infudir uma formulação de droga fluida através da microagulha inserida e no espaço supracional do olho, em que a formulação de droga fluida infundidade flui dentro do espaço supracional distante do sítio de inserção durante a infusão. a formulação de droga fluida pode fluir circunferencialmente na direção do tecido retinocorroidal, mácula e nervo ótico no segmento posterior do olho.
BR112012027416A 2010-04-26 2011-04-26 métodos e dispositivos para distribuição de droga a tecido ocular utilizando microagulha BR112012027416A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/767,768 US8197435B2 (en) 2006-05-02 2010-04-26 Methods and devices for drug delivery to ocular tissue using microneedle
PCT/US2011/033987 WO2011139713A2 (en) 2010-04-26 2011-04-26 Methods and devices for drug delivery to ocular tissue using microneedle

Publications (2)

Publication Number Publication Date
BR112012027416A2 BR112012027416A2 (pt) 2021-07-06
BR112012027416A8 true BR112012027416A8 (pt) 2021-08-17

Family

ID=44904342

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012027416A BR112012027416A8 (pt) 2010-04-26 2011-04-26 métodos e dispositivos para distribuição de droga a tecido ocular utilizando microagulha

Country Status (15)

Country Link
US (7) US8197435B2 (pt)
EP (1) EP2563429B1 (pt)
JP (2) JP5996526B2 (pt)
CN (2) CN104921868B (pt)
AU (2) AU2011248624B2 (pt)
BR (1) BR112012027416A8 (pt)
CA (1) CA2797258C (pt)
ES (1) ES2804027T3 (pt)
IL (1) IL222638A (pt)
MX (1) MX360969B (pt)
NZ (3) NZ701069A (pt)
RU (1) RU2635320C2 (pt)
SG (1) SG185034A1 (pt)
WO (1) WO2011139713A2 (pt)
ZA (2) ZA201208069B (pt)

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JP2013525022A (ja) 2013-06-20
US8808225B2 (en) 2014-08-19
AU2015230874B2 (en) 2018-07-05
US20120226260A1 (en) 2012-09-06
US20200237556A1 (en) 2020-07-30
WO2011139713A2 (en) 2011-11-10
JP5996526B2 (ja) 2016-09-21
CA2797258C (en) 2018-03-20
IL222638A0 (en) 2012-12-31
US9788995B2 (en) 2017-10-17
MX2012012495A (es) 2013-01-29
US20100256597A1 (en) 2010-10-07
AU2011248624A1 (en) 2012-11-15
RU2012147341A (ru) 2014-06-10
ES2804027T3 (es) 2021-02-02
AU2011248624B2 (en) 2015-11-05
RU2635320C2 (ru) 2017-11-10
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NZ623752A (en) 2015-07-31
CN104921868B (zh) 2017-08-18
US20140107566A1 (en) 2014-04-17
WO2011139713A3 (en) 2012-04-05
BR112012027416A2 (pt) 2021-07-06
US20180028357A1 (en) 2018-02-01
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IL222638A (en) 2017-05-29
US20120232522A1 (en) 2012-09-13
US8636713B2 (en) 2014-01-28
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EP2563429A4 (en) 2015-03-04
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US8197435B2 (en) 2012-06-12
US10905586B2 (en) 2021-02-02
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US10632013B2 (en) 2020-04-28
US20210022918A1 (en) 2021-01-28

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