BR112012019757A2 - composição imunogênica, e, método para induzir uma resposta imune a um polissacarídeo capsular - Google Patents

composição imunogênica, e, método para induzir uma resposta imune a um polissacarídeo capsular

Info

Publication number
BR112012019757A2
BR112012019757A2 BR112012019757A BR112012019757A BR112012019757A2 BR 112012019757 A2 BR112012019757 A2 BR 112012019757A2 BR 112012019757 A BR112012019757 A BR 112012019757A BR 112012019757 A BR112012019757 A BR 112012019757A BR 112012019757 A2 BR112012019757 A2 BR 112012019757A2
Authority
BR
Brazil
Prior art keywords
inducing
immune response
immunogenic composition
capsular polysaccharide
capsular
Prior art date
Application number
BR112012019757A
Other languages
English (en)
Other versions
BR112012019757B1 (pt
BR112012019757B8 (pt
Inventor
Jayme L Cannon
Jeffrey T Blue
Michael J Caulfield
Patrick L Ahl
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of BR112012019757A2 publication Critical patent/BR112012019757A2/pt
Publication of BR112012019757B1 publication Critical patent/BR112012019757B1/pt
Publication of BR112012019757B8 publication Critical patent/BR112012019757B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112012019757A 2010-02-09 2011-02-03 Composição imunogênica, e, uso de uma mistura de conjugado de polissacarídeo-proteína multivalente BR112012019757B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30272610P 2010-02-09 2010-02-09
US61/302726 2010-02-09
PCT/US2011/023526 WO2011100151A1 (en) 2010-02-09 2011-02-03 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition

Publications (3)

Publication Number Publication Date
BR112012019757A2 true BR112012019757A2 (pt) 2016-05-10
BR112012019757B1 BR112012019757B1 (pt) 2020-11-17
BR112012019757B8 BR112012019757B8 (pt) 2023-04-25

Family

ID=44353903

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012019757A BR112012019757B8 (pt) 2010-02-09 2011-02-03 Composição imunogênica, e, uso de uma mistura de conjugado de polissacarídeo-proteína multivalente

Country Status (24)

Country Link
US (2) US8192746B2 (pt)
EP (1) EP2533805A4 (pt)
JP (2) JP2013518891A (pt)
KR (1) KR101538535B1 (pt)
CN (1) CN102858365A (pt)
AR (2) AR080122A1 (pt)
AU (1) AU2011216095B2 (pt)
BR (1) BR112012019757B8 (pt)
CA (1) CA2788680C (pt)
CL (1) CL2012002195A1 (pt)
EC (1) ECSP12012100A (pt)
IL (1) IL221283A0 (pt)
MA (1) MA34051B1 (pt)
MX (1) MX2012009206A (pt)
MY (1) MY159984A (pt)
NZ (1) NZ601711A (pt)
PE (1) PE20121698A1 (pt)
RU (1) RU2012138368A (pt)
SG (2) SG10201500350PA (pt)
TN (1) TN2012000377A1 (pt)
TW (1) TW201136603A (pt)
UA (1) UA106115C2 (pt)
WO (1) WO2011100151A1 (pt)
ZA (1) ZA201205737B (pt)

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EP4365196A2 (en) 2011-04-22 2024-05-08 Wyeth LLC Compositions relating to a mutant clostridium difficile toxin and methods thereof
US9573811B2 (en) * 2011-11-23 2017-02-21 Merck Sharp & Dohme Corp. Method for preparation of aluminum hydroxyphosphate adjuvant
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US20140193451A1 (en) * 2012-10-17 2014-07-10 Glaxosmithkline Biologicals Sa Immunogenic composition
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CN112673054A (zh) * 2018-07-19 2021-04-16 葛兰素史密丝克莱恩生物有限公司 用于制备干燥多糖的方法
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Also Published As

Publication number Publication date
BR112012019757B1 (pt) 2020-11-17
CA2788680A1 (en) 2011-08-18
TW201136603A (en) 2011-11-01
ZA201205737B (en) 2013-04-24
JP2014012720A (ja) 2014-01-23
KR20120114345A (ko) 2012-10-16
EP2533805A4 (en) 2013-08-28
BR112012019757B8 (pt) 2023-04-25
RU2012138368A (ru) 2014-03-20
MY159984A (en) 2017-02-15
TN2012000377A1 (en) 2014-01-30
KR101538535B1 (ko) 2015-07-22
AU2011216095B2 (en) 2013-07-18
US8192746B2 (en) 2012-06-05
CN102858365A (zh) 2013-01-02
MX2012009206A (es) 2012-08-23
ECSP12012100A (es) 2013-03-28
MA34051B1 (fr) 2013-03-05
UA106115C2 (uk) 2014-07-25
WO2011100151A1 (en) 2011-08-18
SG183199A1 (en) 2012-09-27
JP2013518891A (ja) 2013-05-23
US20110195086A1 (en) 2011-08-11
EP2533805A1 (en) 2012-12-19
SG10201500350PA (en) 2015-03-30
US20120301502A1 (en) 2012-11-29
AR116043A2 (es) 2021-03-25
AR080122A1 (es) 2012-03-14
CL2012002195A1 (es) 2012-11-30
PE20121698A1 (es) 2012-12-11
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