CL2012002195A1 - Composicion inmunogénica que comprende una mezcla de conjugados de polisacaridos-proteina multivalente que consiste en polisacáridos capsulares de streptococcus pneumoniae; metodo para inducir una respuesta inmune a un polisacarido capsular de streptococcus pneumoniae. - Google Patents

Composicion inmunogénica que comprende una mezcla de conjugados de polisacaridos-proteina multivalente que consiste en polisacáridos capsulares de streptococcus pneumoniae; metodo para inducir una respuesta inmune a un polisacarido capsular de streptococcus pneumoniae.

Info

Publication number
CL2012002195A1
CL2012002195A1 CL2012002195A CL2012002195A CL2012002195A1 CL 2012002195 A1 CL2012002195 A1 CL 2012002195A1 CL 2012002195 A CL2012002195 A CL 2012002195A CL 2012002195 A CL2012002195 A CL 2012002195A CL 2012002195 A1 CL2012002195 A1 CL 2012002195A1
Authority
CL
Chile
Prior art keywords
streptococcus pneumoniae
polysaccharide
capsular
induce
mixture
Prior art date
Application number
CL2012002195A
Other languages
English (en)
Inventor
Michael J Caufield
Patrick L Ahl
Jeffrey T Blue
Jayme L Cannon
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of CL2012002195A1 publication Critical patent/CL2012002195A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Composición inmunogénica que comprende una mezcla de conjugados de polisacáridos-proteína multivalente que consiste en polisacáridos capsulares de Streptococcus Pneumoniae; método para inducir una respuesta inmune a un polisacárido capsular de Streptococcus Pneumoniae.
CL2012002195A 2010-02-09 2012-08-07 Composicion inmunogénica que comprende una mezcla de conjugados de polisacaridos-proteina multivalente que consiste en polisacáridos capsulares de streptococcus pneumoniae; metodo para inducir una respuesta inmune a un polisacarido capsular de streptococcus pneumoniae. CL2012002195A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30272610P 2010-02-09 2010-02-09

Publications (1)

Publication Number Publication Date
CL2012002195A1 true CL2012002195A1 (es) 2012-11-30

Family

ID=44353903

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012002195A CL2012002195A1 (es) 2010-02-09 2012-08-07 Composicion inmunogénica que comprende una mezcla de conjugados de polisacaridos-proteina multivalente que consiste en polisacáridos capsulares de streptococcus pneumoniae; metodo para inducir una respuesta inmune a un polisacarido capsular de streptococcus pneumoniae.

Country Status (24)

Country Link
US (2) US20120301502A1 (es)
EP (1) EP2533805A4 (es)
JP (2) JP2013518891A (es)
KR (1) KR101538535B1 (es)
CN (1) CN102858365A (es)
AR (2) AR080122A1 (es)
AU (1) AU2011216095B2 (es)
BR (1) BR112012019757B8 (es)
CA (1) CA2788680C (es)
CL (1) CL2012002195A1 (es)
EC (1) ECSP12012100A (es)
IL (1) IL221283A0 (es)
MA (1) MA34051B1 (es)
MX (1) MX2012009206A (es)
MY (1) MY159984A (es)
NZ (1) NZ601711A (es)
PE (1) PE20121698A1 (es)
RU (1) RU2012138368A (es)
SG (2) SG183199A1 (es)
TN (1) TN2012000377A1 (es)
TW (1) TW201136603A (es)
UA (1) UA106115C2 (es)
WO (1) WO2011100151A1 (es)
ZA (1) ZA201205737B (es)

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Also Published As

Publication number Publication date
AR116043A2 (es) 2021-03-25
TW201136603A (en) 2011-11-01
MY159984A (en) 2017-02-15
KR101538535B1 (ko) 2015-07-22
US20120301502A1 (en) 2012-11-29
US8192746B2 (en) 2012-06-05
CA2788680C (en) 2014-12-16
TN2012000377A1 (en) 2014-01-30
US20110195086A1 (en) 2011-08-11
NZ601711A (en) 2014-03-28
AU2011216095A1 (en) 2012-08-09
ZA201205737B (en) 2013-04-24
JP2014012720A (ja) 2014-01-23
RU2012138368A (ru) 2014-03-20
EP2533805A1 (en) 2012-12-19
WO2011100151A1 (en) 2011-08-18
IL221283A0 (en) 2012-10-31
BR112012019757B1 (pt) 2020-11-17
PE20121698A1 (es) 2012-12-11
AU2011216095B2 (en) 2013-07-18
CN102858365A (zh) 2013-01-02
UA106115C2 (uk) 2014-07-25
JP2013518891A (ja) 2013-05-23
BR112012019757A2 (pt) 2016-05-10
SG183199A1 (en) 2012-09-27
KR20120114345A (ko) 2012-10-16
ECSP12012100A (es) 2013-03-28
SG10201500350PA (en) 2015-03-30
CA2788680A1 (en) 2011-08-18
AR080122A1 (es) 2012-03-14
BR112012019757B8 (pt) 2023-04-25
MX2012009206A (es) 2012-08-23
EP2533805A4 (en) 2013-08-28
MA34051B1 (fr) 2013-03-05

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