BR0311708A - Comprimidos que se desintegram oralmente e processo de obtenção dos mesmos - Google Patents

Comprimidos que se desintegram oralmente e processo de obtenção dos mesmos

Info

Publication number
BR0311708A
BR0311708A BR0311708-1A BR0311708A BR0311708A BR 0311708 A BR0311708 A BR 0311708A BR 0311708 A BR0311708 A BR 0311708A BR 0311708 A BR0311708 A BR 0311708A
Authority
BR
Brazil
Prior art keywords
weight
tablets
particle size
active ingredient
microcrystalline cellulose
Prior art date
Application number
BR0311708-1A
Other languages
English (en)
Inventor
Javier Segado Ferran
Original Assignee
Vita Cientifica S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29724735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0311708(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vita Cientifica S L filed Critical Vita Cientifica S L
Publication of BR0311708A publication Critical patent/BR0311708A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPRIMIDOS QUE SE DESINTEGRAM ORALMENTE E PROCESSO DE OBTENçãO DOS MESMOS". Os comprimidos compreendem: pelo menos 59,5 % de manitol seco em atomização; ingrediente ativo abaixo ou igual a 10 %, em que pelo menos 90 % em peso do ingrediente ativo têm um tamanho de partícula abaixo de que 100 <109>m; celulose microcristalina 10 - 18 %, com um tamanho médio de partícula de 50 <109>m e em que pelo menos 99 % em peso de celulose microcristalina têm um tamanho de partícula abaixo de 250 <109>m; croscarmelose de sódio 1 - 4 % e um agente lubrificante 0,5 - 2 %; em que, a não ser se for especificado de outra maneira, as percentagens estão expressas em peso do peso total do comprimido. E também um processo que compreende: peneiração e misturação de componentes exceto para o agente lubrificante; misturação de todos os componentes e compressão direta da mistura final. Os comprimidos da invenção fornecem menores tempos de desintegração assim como boa percepção sobre a língua após a desintegração e superam o problema de resistência mecânica insuficiente para operações de embalagem e de transporte.
BR0311708-1A 2002-06-10 2003-06-04 Comprimidos que se desintegram oralmente e processo de obtenção dos mesmos BR0311708A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200201440A ES2199061B1 (es) 2002-06-10 2002-06-10 Comprimidos bucodispersables y procedimiento para su obtencion.
PCT/IB2003/002446 WO2003103629A1 (en) 2002-06-10 2003-06-04 Orally disintegrating tablets and process for obtaining them.

Publications (1)

Publication Number Publication Date
BR0311708A true BR0311708A (pt) 2005-03-15

Family

ID=29724735

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0311708-1A BR0311708A (pt) 2002-06-10 2003-06-04 Comprimidos que se desintegram oralmente e processo de obtenção dos mesmos

Country Status (33)

Country Link
US (1) US20060165781A1 (pt)
EP (1) EP1534237B1 (pt)
JP (1) JP2005533045A (pt)
KR (1) KR100826819B1 (pt)
CN (1) CN100428926C (pt)
AR (1) AR040183A1 (pt)
AT (1) ATE422154T1 (pt)
AU (1) AU2003232415B2 (pt)
BR (1) BR0311708A (pt)
CA (1) CA2487834C (pt)
CY (1) CY1108961T1 (pt)
DE (1) DE60326074D1 (pt)
DK (1) DK1534237T3 (pt)
EG (1) EG25919A (pt)
ES (2) ES2199061B1 (pt)
HK (1) HK1076252A1 (pt)
HR (1) HRP20041158B1 (pt)
IL (1) IL165523A (pt)
JO (1) JO2560B1 (pt)
MA (1) MA27309A1 (pt)
MX (1) MXPA04012464A (pt)
MY (1) MY139585A (pt)
NO (1) NO334159B1 (pt)
NZ (1) NZ536966A (pt)
PE (1) PE20040069A1 (pt)
PL (1) PL207009B1 (pt)
PT (1) PT1534237E (pt)
RU (1) RU2321389C2 (pt)
SA (1) SA03240275B1 (pt)
SI (1) SI1534237T1 (pt)
TW (1) TWI288002B (pt)
WO (1) WO2003103629A1 (pt)
ZA (1) ZA200409894B (pt)

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US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
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CN102088959B (zh) * 2008-06-20 2016-05-25 默克专利股份有限公司 可直接压缩的且快速崩解的片剂基质
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Also Published As

Publication number Publication date
HRP20041158A2 (en) 2005-04-30
ZA200409894B (en) 2006-05-31
AR040183A1 (es) 2005-03-16
US20060165781A1 (en) 2006-07-27
SA03240275B1 (ar) 2008-11-19
SI1534237T1 (sl) 2009-06-30
MXPA04012464A (es) 2005-06-08
DK1534237T3 (da) 2009-05-04
AU2003232415A1 (en) 2003-12-22
KR20050062467A (ko) 2005-06-23
EP1534237A1 (en) 2005-06-01
AU2003232415B2 (en) 2008-05-15
RU2004135377A (ru) 2005-09-10
ES2199061A1 (es) 2004-02-01
PE20040069A1 (es) 2004-03-25
JP2005533045A (ja) 2005-11-04
CN1658838A (zh) 2005-08-24
CN100428926C (zh) 2008-10-29
IL165523A0 (en) 2006-01-15
DE60326074D1 (de) 2009-03-19
EG25919A (en) 2012-10-15
CA2487834A1 (en) 2003-12-18
HK1076252A1 (en) 2006-01-13
PT1534237E (pt) 2009-05-05
CY1108961T1 (el) 2014-07-02
MA27309A1 (fr) 2005-05-02
NO334159B1 (no) 2013-12-23
ES2199061B1 (es) 2005-02-16
ATE422154T1 (de) 2009-02-15
RU2321389C2 (ru) 2008-04-10
CA2487834C (en) 2009-07-14
TW200403080A (en) 2004-03-01
NZ536966A (en) 2006-08-31
NO20045577L (no) 2004-12-21
IL165523A (en) 2011-07-31
ES2320753T3 (es) 2009-05-28
PL374197A1 (en) 2005-10-03
PL207009B1 (pl) 2010-10-29
MY139585A (en) 2009-10-30
EP1534237B1 (en) 2009-02-04
HRP20041158B1 (en) 2012-11-30
JO2560B1 (en) 2010-09-05
KR100826819B1 (ko) 2008-05-02
TWI288002B (en) 2007-10-11
WO2003103629A1 (en) 2003-12-18

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B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI.A61K 47/26, A61K 47/36, A61K 47/38, A61K 9/00, A61K 9/20

Ipc: A61K 47/26 (2011.01), A61K 47/36 (2011.01), A61K 4

B25D Requested change of name of applicant approved

Owner name: PROCTER AND GAMBLE PHARMACEUTICALS IBERIA, S.L. (E

Free format text: NOME ALTERADO DE: VITA CIENTIFICA, S.L.

B25G Requested change of headquarter approved

Owner name: PROCTER AND GAMBLE PHARMACEUTICALS IBERIA, S.L. (E

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B25F Entry of change of name and/or headquarter and transfer of application, patent and certif. of addition of invention: change of name on requirement

Owner name: PROCTER AND GAMBLE PHARMACEUTICALS IBERIA, S.L. (E

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B25D Requested change of name of applicant approved

Owner name: WARNER CHILCOTT IBERIA, S.L. (ES)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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Owner name: WARNER CHILCOTT IBERIA, S.L. (ES)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
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