CY1108961T1 - Ταμπλετες που διαλυονται στο στομα και μεθοδος για τη ληψη τους - Google Patents

Ταμπλετες που διαλυονται στο στομα και μεθοδος για τη ληψη τους

Info

Publication number
CY1108961T1
CY1108961T1 CY20091100430T CY091100430T CY1108961T1 CY 1108961 T1 CY1108961 T1 CY 1108961T1 CY 20091100430 T CY20091100430 T CY 20091100430T CY 091100430 T CY091100430 T CY 091100430T CY 1108961 T1 CY1108961 T1 CY 1108961T1
Authority
CY
Cyprus
Prior art keywords
weight
particle size
lubricant
unless
mixing
Prior art date
Application number
CY20091100430T
Other languages
English (en)
Inventor
Ferran Javier Segado
Original Assignee
Procter & Gamble Pharmaceuticals Iberia, S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29724735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1108961(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter & Gamble Pharmaceuticals Iberia, S.L. filed Critical Procter & Gamble Pharmaceuticals Iberia, S.L.
Publication of CY1108961T1 publication Critical patent/CY1108961T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Οι ταμπλέτες περιέχουν: τουλάχιστον 59,5% ξηραμένη με ψεκασμό μαννιτόλη, ενεργό συστατικό κάτω από ή ίσο με 10%, όπου τουλάχιστον το 90% κατά βάρος του ενεργού συστατικού έχει μέγεθος σωματιδίων κάτω από 100 μm, μικροκρυσταλλική κυτταρίνη, 10-18%, με μέσο μέγεθος σωματιδίων 50 μm και όπου τουλάχιστον το 99% κατά βάρος της μικροκρυσταλλικής κυτταρίνης έχει μέγεθος σωματιδίων κάτω των 250 μm, νατριούχο κροσκαρμελόξη 1-4%, και ένα λιπαντικό μέσο 0,5-2%, όπου, εκτός εάν καθορίζεται διαφορετικά, οι εκατοστιαίες αναλογίες εκφράζονται κατά βάρος του συνολικού βάρους του δισκίου. Και επίσης μια μέθοδος που περιλαμβάνει: κοσκίνισμα και ανάμειξη όλων των συστατικών εκτός από το λιπαντικό μέσο, ανάμειξη όλων των συστατικών, και απ' ευθείας συμπίεση του τελικού μίγματος. Οι ταμπλέτες της εφεύρεσης δίνουν μικρότερους χρόνους διάλυσης καθώς και καλή, αίσθηση στη γλώσσα μετά τη διάλυση, και εξουδετερώνουν το πρόβλημα της ανεπαρκούς μηχανικής αντοχής για εργασίες συσκευασίας και μεταφοράς.
CY20091100430T 2002-06-10 2009-04-13 Ταμπλετες που διαλυονται στο στομα και μεθοδος για τη ληψη τους CY1108961T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200201440A ES2199061B1 (es) 2002-06-10 2002-06-10 Comprimidos bucodispersables y procedimiento para su obtencion.
EP03757165A EP1534237B1 (en) 2002-06-10 2003-06-04 Orally disintegrating tablets and process for obtaining them.

Publications (1)

Publication Number Publication Date
CY1108961T1 true CY1108961T1 (el) 2014-07-02

Family

ID=29724735

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100430T CY1108961T1 (el) 2002-06-10 2009-04-13 Ταμπλετες που διαλυονται στο στομα και μεθοδος για τη ληψη τους

Country Status (33)

Country Link
US (1) US20060165781A1 (el)
EP (1) EP1534237B1 (el)
JP (1) JP2005533045A (el)
KR (1) KR100826819B1 (el)
CN (1) CN100428926C (el)
AR (1) AR040183A1 (el)
AT (1) ATE422154T1 (el)
AU (1) AU2003232415B2 (el)
BR (1) BR0311708A (el)
CA (1) CA2487834C (el)
CY (1) CY1108961T1 (el)
DE (1) DE60326074D1 (el)
DK (1) DK1534237T3 (el)
EG (1) EG25919A (el)
ES (2) ES2199061B1 (el)
HK (1) HK1076252A1 (el)
HR (1) HRP20041158B1 (el)
IL (1) IL165523A (el)
JO (1) JO2560B1 (el)
MA (1) MA27309A1 (el)
MX (1) MXPA04012464A (el)
MY (1) MY139585A (el)
NO (1) NO334159B1 (el)
NZ (1) NZ536966A (el)
PE (1) PE20040069A1 (el)
PL (1) PL207009B1 (el)
PT (1) PT1534237E (el)
RU (1) RU2321389C2 (el)
SA (1) SA03240275B1 (el)
SI (1) SI1534237T1 (el)
TW (1) TWI288002B (el)
WO (1) WO2003103629A1 (el)
ZA (1) ZA200409894B (el)

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Also Published As

Publication number Publication date
HRP20041158A2 (en) 2005-04-30
ZA200409894B (en) 2006-05-31
AR040183A1 (es) 2005-03-16
US20060165781A1 (en) 2006-07-27
SA03240275B1 (ar) 2008-11-19
SI1534237T1 (sl) 2009-06-30
MXPA04012464A (es) 2005-06-08
DK1534237T3 (da) 2009-05-04
AU2003232415A1 (en) 2003-12-22
KR20050062467A (ko) 2005-06-23
EP1534237A1 (en) 2005-06-01
AU2003232415B2 (en) 2008-05-15
RU2004135377A (ru) 2005-09-10
ES2199061A1 (es) 2004-02-01
PE20040069A1 (es) 2004-03-25
JP2005533045A (ja) 2005-11-04
CN1658838A (zh) 2005-08-24
CN100428926C (zh) 2008-10-29
IL165523A0 (en) 2006-01-15
DE60326074D1 (de) 2009-03-19
EG25919A (en) 2012-10-15
CA2487834A1 (en) 2003-12-18
HK1076252A1 (en) 2006-01-13
PT1534237E (pt) 2009-05-05
MA27309A1 (fr) 2005-05-02
NO334159B1 (no) 2013-12-23
ES2199061B1 (es) 2005-02-16
ATE422154T1 (de) 2009-02-15
RU2321389C2 (ru) 2008-04-10
CA2487834C (en) 2009-07-14
TW200403080A (en) 2004-03-01
NZ536966A (en) 2006-08-31
NO20045577L (no) 2004-12-21
BR0311708A (pt) 2005-03-15
IL165523A (en) 2011-07-31
ES2320753T3 (es) 2009-05-28
PL374197A1 (en) 2005-10-03
PL207009B1 (pl) 2010-10-29
MY139585A (en) 2009-10-30
EP1534237B1 (en) 2009-02-04
HRP20041158B1 (en) 2012-11-30
JO2560B1 (en) 2010-09-05
KR100826819B1 (ko) 2008-05-02
TWI288002B (en) 2007-10-11
WO2003103629A1 (en) 2003-12-18

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