BR0308993A - Métodos para desacilação aquosa estabilizada por tampão - Google Patents

Métodos para desacilação aquosa estabilizada por tampão

Info

Publication number
BR0308993A
BR0308993A BR0308993-2A BR0308993A BR0308993A BR 0308993 A BR0308993 A BR 0308993A BR 0308993 A BR0308993 A BR 0308993A BR 0308993 A BR0308993 A BR 0308993A
Authority
BR
Brazil
Prior art keywords
sucralose
acyl
present
compound
methods
Prior art date
Application number
BR0308993-2A
Other languages
English (en)
Inventor
Nicholas M Vernon
Edward Micinski
Steven J Catani
Juan L Navia
Original Assignee
Tate & Lyle Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tate & Lyle Plc filed Critical Tate & Lyle Plc
Publication of BR0308993A publication Critical patent/BR0308993A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/37—Halogenated sugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MéTODOS PARA DESACILAçãO AQUOSA ESTABILIZADA POR TAMPãO". A presente invenção refere-se a novos métodos para estabilizar desacilação aquosa, por meio do uso de tampões, na produção de sucralose. A presente invenção fornece um processo para produzir sucralose de um composto de acil-sucralose por meio do qual o composto de acil-sucralose é desacilado na presença de um agente de tamponamento, que estabiliza o pH da mistura de alimentação e diminui o acúmulo de compostos de anidro indesejados. Além disso, a presente invenção fornece um processo por meio do qual o composto de acil-sucralose é desacilado diretamente ou antes ou após a remoção do veículo de reação de amida terciária da mistura de alimentação de clorinação neutralizada. Uma solução aquosa de sucralose incluindo sais e outros compostos é produzida, da qual a sucralose é recuperada por extração e purificada por cristalização.
BR0308993-2A 2002-04-05 2003-04-04 Métodos para desacilação aquosa estabilizada por tampão BR0308993A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/116,758 US6890581B2 (en) 2002-04-05 2002-04-05 Methods for buffer stabilized aqueous deacylation
PCT/US2003/010349 WO2003087117A1 (en) 2002-04-05 2003-04-04 Methods for buffer stabilized aqueous deacylation

Publications (1)

Publication Number Publication Date
BR0308993A true BR0308993A (pt) 2005-01-04

Family

ID=28674058

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308993-2A BR0308993A (pt) 2002-04-05 2003-04-04 Métodos para desacilação aquosa estabilizada por tampão

Country Status (15)

Country Link
US (2) US6890581B2 (pt)
EP (1) EP1492802B1 (pt)
JP (1) JP4619659B2 (pt)
KR (1) KR100981629B1 (pt)
CN (1) CN1284792C (pt)
AT (1) ATE445629T1 (pt)
AU (1) AU2003221797B2 (pt)
BR (1) BR0308993A (pt)
CA (1) CA2481407A1 (pt)
DE (1) DE60329664D1 (pt)
ES (1) ES2332507T3 (pt)
IL (1) IL164404A0 (pt)
MX (1) MXPA04009720A (pt)
RU (1) RU2325394C2 (pt)
WO (1) WO2003087117A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050249843A1 (en) * 2004-05-07 2005-11-10 Loren Wallis Low carbohydrate caramel corn composition
WO2006061854A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited CONTROL OF pH BY DIRECT ADDITION OF CARBONATES AND BICARBONATES DURING CONCENTRATION OF ORGANIC SOLVENT EXTRACTS OF 6- ACETYL- 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE AND 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE
US8597714B1 (en) 2005-03-17 2013-12-03 Graceland Fruit, Inc. No sugar added dried and dessert fruits and processes for preparing the same
US20100190975A1 (en) * 2005-06-01 2010-07-29 Pharmed Medicare Private Limited Method for purification of chlorinated sucrose derivatives by solvent extraction
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
US7566463B2 (en) * 2006-05-03 2009-07-28 C. B. Fleet Company Oral rehydration compositions
BRPI0621844A2 (pt) * 2006-07-06 2013-03-19 Alembic Ltd processo aperfeiÇoado para a preparaÇço de sucralose de alta pureza
CN101260127B (zh) * 2007-03-06 2011-04-20 盐城捷康三氯蔗糖制造有限公司 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
US8557976B2 (en) * 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
US8476424B2 (en) * 2008-03-20 2013-07-02 Tate & Lyle Technology Limited Removal of acids from tertiary amide solvents
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
US8212022B2 (en) * 2008-04-03 2012-07-03 Tate & Lyle Technology Limited Effect of carbohydrate concentration on sucralose extraction efficiency
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
GB2468936B (en) 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
GB2471348B (en) 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
US10227367B2 (en) 2013-12-16 2019-03-12 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
WO2016020635A1 (en) 2014-08-08 2016-02-11 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
CN106860405B (zh) * 2015-12-14 2021-02-09 山东新时代药业有限公司 一种法罗培南钠颗粒剂及其制备方法
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
CN110078189B (zh) * 2019-03-29 2022-03-15 翁源广业清怡食品科技有限公司 一种氯代反应液的中和方法
US20220175004A1 (en) * 2020-10-24 2022-06-09 Mason Cave Low viscosity thc apparatus and method of manufacture thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435440A (en) * 1976-01-08 1984-03-06 Tate & Lyle Limited Sweeteners
GB2065646B (en) 1979-12-18 1983-10-05 Tate & Lyle Ltd Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
DE3062467D1 (en) * 1979-12-20 1983-04-28 Tate & Lyle Plc Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
DE3165986D1 (en) * 1980-07-08 1984-10-18 Tate & Lyle Plc Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
CA1183133A (en) * 1980-10-28 1985-02-26 Tate & Lyle Public Limited Company Sweet chlorine-substituted disaccharides
US4980473A (en) 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
GB8525871D0 (en) * 1985-10-21 1985-11-27 Tate & Lyle Plc Chemical compound
GB8617222D0 (en) 1986-07-15 1986-08-20 Tate & Lyle Plc Sweetener
GB8627139D0 (en) * 1986-11-13 1986-12-10 Tate & Lyle Plc Sweetening composition
US4950746A (en) * 1988-07-18 1990-08-21 Noramco, Inc. Process for synthesizing sucrose derivatives by regioselective reaction
US4980463A (en) 1989-07-18 1990-12-25 Noramco, Inc. Sucrose-6-ester chlorination
US5023329A (en) * 1990-04-23 1991-06-11 Noramco, Inc. Sucrose-6-ester production process
US5034551A (en) * 1990-04-23 1991-07-23 Noramco, Inc. Process for recovery of organotin esters from reaction mixtures containing the same and re-use of the recovered organotin compounds
US5470969A (en) * 1990-08-27 1995-11-28 Mcneil-Ppc, Inc. Catalyzed sucrose-6-ester process
US5530106A (en) * 1993-03-12 1996-06-25 Mcneil-Ppc, Inc. Recovery of sucralose intermediates
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
GB9517281D0 (en) * 1995-08-23 1995-10-25 Tate & Lyle Plc Solid sucralose
IL131394A0 (en) * 1997-02-13 2001-01-28 Mcneil Ppc Inc Chromatographic purification of chlorinated sucrose
US7049435B2 (en) * 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose

Also Published As

Publication number Publication date
EP1492802A1 (en) 2005-01-05
DE60329664D1 (de) 2009-11-26
US6890581B2 (en) 2005-05-10
MXPA04009720A (es) 2005-07-14
IL164404A0 (en) 2005-12-18
KR100981629B1 (ko) 2010-09-10
AU2003221797B2 (en) 2009-07-09
ES2332507T3 (es) 2010-02-08
CN1284792C (zh) 2006-11-15
AU2003221797A1 (en) 2003-10-27
EP1492802B1 (en) 2009-10-14
JP2005530731A (ja) 2005-10-13
ATE445629T1 (de) 2009-10-15
US20030190395A1 (en) 2003-10-09
RU2004132231A (ru) 2005-04-20
KR20050011740A (ko) 2005-01-29
CA2481407A1 (en) 2003-10-23
RU2325394C2 (ru) 2008-05-27
US20050170069A1 (en) 2005-08-04
JP4619659B2 (ja) 2011-01-26
WO2003087117A1 (en) 2003-10-23
CN1646553A (zh) 2005-07-27

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: TATE AND LYLE TECHNOLOGY LIMITED (GB)

Free format text: TRANSFERIDO DE: TATE AND LYLE PUBLIC LIMITED COMPANY

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 8A E 9A ANUIDADES.

B15K Others concerning applications: alteration of classification

Ipc: C07H 5/02 (2006.01), A23L 2/60 (2006.01), A23L 27/