DE60329664D1 - Verfahren zur pufferstabilisierten wässrigen deacetylierung - Google Patents

Verfahren zur pufferstabilisierten wässrigen deacetylierung

Info

Publication number
DE60329664D1
DE60329664D1 DE60329664T DE60329664T DE60329664D1 DE 60329664 D1 DE60329664 D1 DE 60329664D1 DE 60329664 T DE60329664 T DE 60329664T DE 60329664 T DE60329664 T DE 60329664T DE 60329664 D1 DE60329664 D1 DE 60329664D1
Authority
DE
Germany
Prior art keywords
sucralose
acyl
present
compound
deacetylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60329664T
Other languages
English (en)
Inventor
Nicholas M Vernon
Edward Micinski
Steven J Catani
Juan L Navia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tate and Lyle Technology Ltd
Original Assignee
Tate and Lyle Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tate and Lyle Technology Ltd filed Critical Tate and Lyle Technology Ltd
Application granted granted Critical
Publication of DE60329664D1 publication Critical patent/DE60329664D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/37—Halogenated sugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
DE60329664T 2002-04-05 2003-04-04 Verfahren zur pufferstabilisierten wässrigen deacetylierung Expired - Fee Related DE60329664D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/116,758 US6890581B2 (en) 2002-04-05 2002-04-05 Methods for buffer stabilized aqueous deacylation
PCT/US2003/010349 WO2003087117A1 (en) 2002-04-05 2003-04-04 Methods for buffer stabilized aqueous deacylation

Publications (1)

Publication Number Publication Date
DE60329664D1 true DE60329664D1 (de) 2009-11-26

Family

ID=28674058

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60329664T Expired - Fee Related DE60329664D1 (de) 2002-04-05 2003-04-04 Verfahren zur pufferstabilisierten wässrigen deacetylierung

Country Status (15)

Country Link
US (2) US6890581B2 (de)
EP (1) EP1492802B1 (de)
JP (1) JP4619659B2 (de)
KR (1) KR100981629B1 (de)
CN (1) CN1284792C (de)
AT (1) ATE445629T1 (de)
AU (1) AU2003221797B2 (de)
BR (1) BR0308993A (de)
CA (1) CA2481407A1 (de)
DE (1) DE60329664D1 (de)
ES (1) ES2332507T3 (de)
IL (1) IL164404A0 (de)
MX (1) MXPA04009720A (de)
RU (1) RU2325394C2 (de)
WO (1) WO2003087117A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050249843A1 (en) * 2004-05-07 2005-11-10 Loren Wallis Low carbohydrate caramel corn composition
WO2006061854A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited CONTROL OF pH BY DIRECT ADDITION OF CARBONATES AND BICARBONATES DURING CONCENTRATION OF ORGANIC SOLVENT EXTRACTS OF 6- ACETYL- 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE AND 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE
US8597714B1 (en) 2005-03-17 2013-12-03 Graceland Fruit, Inc. No sugar added dried and dessert fruits and processes for preparing the same
US20100190975A1 (en) * 2005-06-01 2010-07-29 Pharmed Medicare Private Limited Method for purification of chlorinated sucrose derivatives by solvent extraction
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
US7566463B2 (en) * 2006-05-03 2009-07-28 C. B. Fleet Company Oral rehydration compositions
BRPI0621844A2 (pt) * 2006-07-06 2013-03-19 Alembic Ltd processo aperfeiÇoado para a preparaÇço de sucralose de alta pureza
CN101260127B (zh) * 2007-03-06 2011-04-20 盐城捷康三氯蔗糖制造有限公司 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
US8557976B2 (en) * 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
US8476424B2 (en) * 2008-03-20 2013-07-02 Tate & Lyle Technology Limited Removal of acids from tertiary amide solvents
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
US8212022B2 (en) * 2008-04-03 2012-07-03 Tate & Lyle Technology Limited Effect of carbohydrate concentration on sucralose extraction efficiency
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
GB2468936B (en) 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
GB2471348B (en) 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
US10227367B2 (en) 2013-12-16 2019-03-12 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
WO2016020635A1 (en) 2014-08-08 2016-02-11 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
CN106860405B (zh) * 2015-12-14 2021-02-09 山东新时代药业有限公司 一种法罗培南钠颗粒剂及其制备方法
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
CN110078189B (zh) * 2019-03-29 2022-03-15 翁源广业清怡食品科技有限公司 一种氯代反应液的中和方法
US20220175004A1 (en) * 2020-10-24 2022-06-09 Mason Cave Low viscosity thc apparatus and method of manufacture thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435440A (en) * 1976-01-08 1984-03-06 Tate & Lyle Limited Sweeteners
GB2065646B (en) 1979-12-18 1983-10-05 Tate & Lyle Ltd Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
DE3062467D1 (en) * 1979-12-20 1983-04-28 Tate & Lyle Plc Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
DE3165986D1 (en) * 1980-07-08 1984-10-18 Tate & Lyle Plc Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
CA1183133A (en) * 1980-10-28 1985-02-26 Tate & Lyle Public Limited Company Sweet chlorine-substituted disaccharides
US4980473A (en) 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
GB8525871D0 (en) * 1985-10-21 1985-11-27 Tate & Lyle Plc Chemical compound
GB8617222D0 (en) 1986-07-15 1986-08-20 Tate & Lyle Plc Sweetener
GB8627139D0 (en) * 1986-11-13 1986-12-10 Tate & Lyle Plc Sweetening composition
US4950746A (en) * 1988-07-18 1990-08-21 Noramco, Inc. Process for synthesizing sucrose derivatives by regioselective reaction
US4980463A (en) 1989-07-18 1990-12-25 Noramco, Inc. Sucrose-6-ester chlorination
US5023329A (en) * 1990-04-23 1991-06-11 Noramco, Inc. Sucrose-6-ester production process
US5034551A (en) * 1990-04-23 1991-07-23 Noramco, Inc. Process for recovery of organotin esters from reaction mixtures containing the same and re-use of the recovered organotin compounds
US5470969A (en) * 1990-08-27 1995-11-28 Mcneil-Ppc, Inc. Catalyzed sucrose-6-ester process
US5530106A (en) * 1993-03-12 1996-06-25 Mcneil-Ppc, Inc. Recovery of sucralose intermediates
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
GB9517281D0 (en) * 1995-08-23 1995-10-25 Tate & Lyle Plc Solid sucralose
IL131394A0 (en) * 1997-02-13 2001-01-28 Mcneil Ppc Inc Chromatographic purification of chlorinated sucrose
US7049435B2 (en) * 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose

Also Published As

Publication number Publication date
EP1492802A1 (de) 2005-01-05
US6890581B2 (en) 2005-05-10
MXPA04009720A (es) 2005-07-14
IL164404A0 (en) 2005-12-18
KR100981629B1 (ko) 2010-09-10
AU2003221797B2 (en) 2009-07-09
BR0308993A (pt) 2005-01-04
ES2332507T3 (es) 2010-02-08
CN1284792C (zh) 2006-11-15
AU2003221797A1 (en) 2003-10-27
EP1492802B1 (de) 2009-10-14
JP2005530731A (ja) 2005-10-13
ATE445629T1 (de) 2009-10-15
US20030190395A1 (en) 2003-10-09
RU2004132231A (ru) 2005-04-20
KR20050011740A (ko) 2005-01-29
CA2481407A1 (en) 2003-10-23
RU2325394C2 (ru) 2008-05-27
US20050170069A1 (en) 2005-08-04
JP4619659B2 (ja) 2011-01-26
WO2003087117A1 (en) 2003-10-23
CN1646553A (zh) 2005-07-27

Similar Documents

Publication Publication Date Title
DE60329664D1 (de) Verfahren zur pufferstabilisierten wässrigen deacetylierung
MY113405A (en) Production of sucralose without intermediate isolation of crystalline sucralose -6-ester
BRPI0520252A2 (pt) método de desacilar sucralose-6-éster
ATE466978T1 (de) Verfahren zur herstellung von celluloseregeneratfaser durch zweistufigen fällbadprozess
AP1709A (en) Ethanolate of azithromycin, process for manufacure, and pharmaceutical compositions thereof.
EP1734033A4 (de) Verfahren zur aufreinigung von aminosäuren
BR0308292A (pt) Processo para aperfeiçoar a pureza e o rendimento da sucralose
MX2009005664A (es) D-isoglutamil-d-triptofano cristalino, y la sal monoamonica de d-isoglutamil-d-triptofano.
DE60133083D1 (de) Verfahren zur herstellung von azithromycin-dihydrat
ES2362210T3 (es) Derivados de lactosamina novedosos.
TW200722434A (en) Stereoselective synthesis of β-nucleosides
EP3209674A1 (de) Anthelminthische makrolidsynthese
ATE358709T1 (de) Verfahren zur herstellung einer lösung enthaltend natriumchlorid und natriumhypochlorid
IL183271A0 (en) Crystalline form of cefdinir ammonium salt as an intermediate for the preparation of pure cefdinir
ATE486867T1 (de) Verfahren zur herstellung von hochreinem meloxicam und meloxicam-kaliumsalz
EA200501734A1 (ru) Способ получения (4-гидрокси-6-оксотетрагидропиран-2-ил)ацетонитрила и его производных
PL2234974T3 (pl) Sposób otrzymywania związku (s)-1-alkilo-2', 6'-pipekoloksylidydu
WO2009087362A3 (en) Method for the production of sucralose
HUP0400216A2 (hu) Eljárás paroxetin HCI előállítására, amely korlátozza a rózsaszín vegyületek képződését
EP1420029A3 (de) Verfahren für die Synthese von Perindopril und seiner pharmazeutisch annehmbaren Salzen
WO2007016208A3 (en) 1,2-benzisoxazole-3-methane-sulfonic acid ammonium salt
DE602004030091D1 (de) Verfahren zur reduktiven deshalogenierung
DE50000487D1 (de) Verfahren zur herstellung von natrium-dicyanamid
MX2015017832A (es) Método de síntesis de nanoparticulas de óxido de zinc utilizando goma de mezquite.
ATE457304T1 (de) Verfahren zur herstellung von 1,2-dichlorethan freien kristallen von zonisamid und hochreinezonisamidkristalle

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee