BR0307196A - Idraparinux (sanorg 34006) para tratamento e profilaxia secundária de eventos tromboembólicos venosos em pacientes com trombose venosa profunda - Google Patents
Idraparinux (sanorg 34006) para tratamento e profilaxia secundária de eventos tromboembólicos venosos em pacientes com trombose venosa profundaInfo
- Publication number
- BR0307196A BR0307196A BR0307196-0A BR0307196A BR0307196A BR 0307196 A BR0307196 A BR 0307196A BR 0307196 A BR0307196 A BR 0307196A BR 0307196 A BR0307196 A BR 0307196A
- Authority
- BR
- Brazil
- Prior art keywords
- patients
- treatment
- sanorg
- idraparinux
- thromboembolic events
- Prior art date
Links
- 238000011321 prophylaxis Methods 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- 206010051055 Deep vein thrombosis Diseases 0.000 title abstract 2
- 206010047249 Venous thrombosis Diseases 0.000 title abstract 2
- MVPQUSQUURLQKF-MCPDASDXSA-E nonasodium;(2s,3s,4s,5r,6r)-6-[(2r,3r,4s,5r,6r)-6-[(2r,3s,4s,5r,6r)-2-carboxylato-4,5-dimethoxy-6-[(2r,3r,4s,5r,6s)-6-methoxy-4,5-disulfonatooxy-2-(sulfonatooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-disulfonatooxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-4,5-di Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)O[C@@H]1[C@@H](OS([O-])(=O)=O)[C@@H](OC)O[C@H](COS([O-])(=O)=O)[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@@H]2[C@@H]([C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3[C@@H]([C@@H](OC)[C@H](O[C@@H]4[C@@H]([C@@H](OC)[C@H](OC)[C@@H](COS([O-])(=O)=O)O4)OC)[C@H](O3)C([O-])=O)OC)[C@@H](COS([O-])(=O)=O)O2)OS([O-])(=O)=O)[C@H](C([O-])=O)O1 MVPQUSQUURLQKF-MCPDASDXSA-E 0.000 title 1
- 208000004043 venous thromboembolism Diseases 0.000 title 1
- AJBMORBNKXNZSF-COSHMZDQSA-N (2s,3s,4s,5r,6r)-6-[(2r,3r,4s,5r,6r)-6-[(2r,3s,4s,5r,6r)-2-carboxy-4,5-dimethoxy-6-[(2r,3r,4s,5r,6s)-6-methoxy-4,5-disulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-disulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dimethoxy-3-[(2r,3r,4s,5r,6r)-3,4 Chemical compound OS(=O)(=O)O[C@@H]1[C@@H](OS(O)(=O)=O)[C@@H](OC)O[C@H](COS(O)(=O)=O)[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@H](O[C@H]3[C@@H]([C@@H](OC)[C@H](O[C@@H]4[C@@H]([C@@H](OC)[C@H](OC)[C@@H](COS(O)(=O)=O)O4)OC)[C@H](O3)C(O)=O)OC)[C@@H](COS(O)(=O)=O)O2)OS(O)(=O)=O)[C@H](C(O)=O)O1 AJBMORBNKXNZSF-COSHMZDQSA-N 0.000 abstract 1
- 208000005189 Embolism Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000009424 thromboembolic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
"IDRAPARINUX (SANORG 34006) PARA TRATAMENTO E PROFILAXIA SECUNDáRIA DE EVENTOS TROMBOEMBóLICOS VENOSOS EM PACIENTES COM TROMBOSE VENOSA PROFUNDA". A invenção refere-se a uma dose de 2,5 mg de pentassacarídeo de ácido metil O-(2,3,4-tri-O-metil-6-O-sulfo-<244>-D-glicopiranosil)-(1<sym>4)-O-(2, 3-di-O-metil-<255>-D-glicopiranosil urónico) - ácido (1<sym>4)-O-(2,3,6-tri-O-sulfo<244>-D-glicopiranosil)-(1<sym>4)-O-(2 ,3-di-O-metil-<244>-L-idopiranosil urónico) - (1<sym>4)2,3,6-tri-O-sulfo-<244>-D-glicopiranosida, ou um sal farmaceuticamente aceitável dele, para uso em terapia, em particular para o tratamento elou profilaxia secundária de eventos tromboembólicos em pacientes com trombose venosa profunda.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02075374 | 2002-01-29 | ||
| PCT/EP2003/000696 WO2003063881A1 (en) | 2002-01-29 | 2003-01-23 | Idraparinux(sanorg 34006)for treatment and secondary prophylaxis of venous thromboemolic events in patients with deep venous thrombosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0307196A true BR0307196A (pt) | 2004-11-03 |
Family
ID=27635850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0307196-0A BR0307196A (pt) | 2002-01-29 | 2003-01-23 | Idraparinux (sanorg 34006) para tratamento e profilaxia secundária de eventos tromboembólicos venosos em pacientes com trombose venosa profunda |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7709463B2 (pt) |
| EP (1) | EP1471924B1 (pt) |
| JP (1) | JP4870907B2 (pt) |
| CN (1) | CN1622813A (pt) |
| AR (1) | AR038320A1 (pt) |
| AT (1) | ATE323497T1 (pt) |
| AU (1) | AU2003205664B2 (pt) |
| BR (1) | BR0307196A (pt) |
| CA (1) | CA2472957C (pt) |
| CY (1) | CY1107661T1 (pt) |
| DE (1) | DE60304678T2 (pt) |
| DK (1) | DK1471924T3 (pt) |
| EA (1) | EA007204B1 (pt) |
| ES (1) | ES2262971T3 (pt) |
| HK (1) | HK1072361A1 (pt) |
| MX (1) | MXPA04007310A (pt) |
| NO (1) | NO332699B1 (pt) |
| PE (1) | PE20030855A1 (pt) |
| PL (1) | PL207144B1 (pt) |
| PT (1) | PT1471924E (pt) |
| SI (1) | SI1471924T1 (pt) |
| TW (1) | TWI281861B (pt) |
| WO (1) | WO2003063881A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0518794A2 (pt) * | 2004-12-01 | 2008-12-09 | Osi Pharm Inc | composto, composiÇço, mÉtodo de tratamento de distérbio hiperproliferativo, e, biblioteca combinatorial |
| US9642822B2 (en) | 2011-05-27 | 2017-05-09 | Children's Medical Center Corporation | Methods for treating and preventing neutrophil-derived net toxicity and thrombosis |
| WO2021007429A1 (en) | 2019-07-09 | 2021-01-14 | Optimvia Llc | Methods for synthesizing anticoagulant polysaccharides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5378829A (en) * | 1990-04-23 | 1995-01-03 | Akzo N.V. | Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type |
-
2003
- 2003-01-14 TW TW092100703A patent/TWI281861B/zh not_active IP Right Cessation
- 2003-01-23 ES ES03702514T patent/ES2262971T3/es not_active Expired - Lifetime
- 2003-01-23 PE PE2003000071A patent/PE20030855A1/es not_active Application Discontinuation
- 2003-01-23 AT AT03702514T patent/ATE323497T1/de active
- 2003-01-23 CA CA2472957A patent/CA2472957C/en not_active Expired - Fee Related
- 2003-01-23 AU AU2003205664A patent/AU2003205664B2/en not_active Ceased
- 2003-01-23 CN CNA038028123A patent/CN1622813A/zh active Pending
- 2003-01-23 MX MXPA04007310A patent/MXPA04007310A/es active IP Right Grant
- 2003-01-23 EA EA200400817A patent/EA007204B1/ru not_active IP Right Cessation
- 2003-01-23 JP JP2003563570A patent/JP4870907B2/ja not_active Expired - Fee Related
- 2003-01-23 EP EP03702514A patent/EP1471924B1/en not_active Expired - Lifetime
- 2003-01-23 DE DE60304678T patent/DE60304678T2/de not_active Expired - Lifetime
- 2003-01-23 DK DK03702514T patent/DK1471924T3/da active
- 2003-01-23 WO PCT/EP2003/000696 patent/WO2003063881A1/en active IP Right Grant
- 2003-01-23 PT PT03702514T patent/PT1471924E/pt unknown
- 2003-01-23 PL PL370557A patent/PL207144B1/pl unknown
- 2003-01-23 SI SI200330334T patent/SI1471924T1/sl unknown
- 2003-01-23 BR BR0307196-0A patent/BR0307196A/pt not_active Application Discontinuation
- 2003-01-23 US US10/502,706 patent/US7709463B2/en not_active Expired - Fee Related
- 2003-01-28 AR ARP030100237A patent/AR038320A1/es not_active Application Discontinuation
-
2004
- 2004-07-27 NO NO20043195A patent/NO332699B1/no not_active IP Right Cessation
-
2005
- 2005-05-03 HK HK05103708A patent/HK1072361A1/xx not_active IP Right Cessation
-
2006
- 2006-07-19 CY CY20061101002T patent/CY1107661T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4870907B2 (ja) | 2012-02-08 |
| ATE323497T1 (de) | 2006-05-15 |
| EP1471924B1 (en) | 2006-04-19 |
| PL207144B1 (pl) | 2010-11-30 |
| DE60304678D1 (de) | 2006-05-24 |
| WO2003063881A1 (en) | 2003-08-07 |
| JP2005519919A (ja) | 2005-07-07 |
| NO332699B1 (no) | 2012-12-10 |
| TWI281861B (en) | 2007-06-01 |
| CA2472957C (en) | 2011-09-13 |
| ES2262971T3 (es) | 2006-12-01 |
| PL370557A1 (en) | 2005-05-30 |
| EA200400817A1 (ru) | 2005-02-24 |
| DE60304678T2 (de) | 2007-04-05 |
| PT1471924E (pt) | 2006-09-29 |
| CY1107661T1 (el) | 2013-04-18 |
| MXPA04007310A (es) | 2004-10-29 |
| US7709463B2 (en) | 2010-05-04 |
| AR038320A1 (es) | 2005-01-12 |
| TW200302104A (en) | 2003-08-01 |
| HK1072361A1 (en) | 2005-08-26 |
| CN1622813A (zh) | 2005-06-01 |
| PE20030855A1 (es) | 2003-10-11 |
| CA2472957A1 (en) | 2003-08-07 |
| EA007204B1 (ru) | 2006-08-25 |
| SI1471924T1 (sl) | 2006-10-31 |
| AU2003205664B2 (en) | 2008-06-05 |
| US20050209175A1 (en) | 2005-09-22 |
| DK1471924T3 (da) | 2006-08-21 |
| EP1471924A1 (en) | 2004-11-03 |
| NO20043195L (no) | 2004-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: SANOFI-AVENTIS (FR) Free format text: ALTERADO DE: SANOFI-SYNTHELABO |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |