BR0212199A - Uso de aminometil cromanos substituìdos no tratamento de distúrbios do movimento - Google Patents

Uso de aminometil cromanos substituìdos no tratamento de distúrbios do movimento

Info

Publication number
BR0212199A
BR0212199A BR0212199-9A BR0212199A BR0212199A BR 0212199 A BR0212199 A BR 0212199A BR 0212199 A BR0212199 A BR 0212199A BR 0212199 A BR0212199 A BR 0212199A
Authority
BR
Brazil
Prior art keywords
treatment
substituted
movement disorders
aminomethyl
chromanite
Prior art date
Application number
BR0212199-9A
Other languages
English (en)
Inventor
Gerd Bartoszyk
Hermann Russ
Christoph Seyfried
Henning Boettcher
Heinz-Hermann Bokel
Uschi Schmid-Grossmann
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR0212199A publication Critical patent/BR0212199A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"USO DE AMINOMETIL CROMANOS SUBSTITUìDOS NO TRATAMENTO DE DISTúRBIOS DO MOVIMENTO". A invenção refere-se a aminometil cromanos substituídos, um de seus isómeros óticos ou sais farmaceuticamente aceitáveis, usados para a produção de um medicamento para o tratamento de efeitos adversos de drogas antiparkinsonianas em distúrbios extrapiramidais do movimento e/ou para a produção de um medicamento para o tratamento de sintomas extrapiramidais (EPS) induzidos por neurolépticos. Um composto preferido é o (-)-(R)-2-{4-[[3,4-dihidro-2H-benzopiran-2-lL)-metil]amino]butil}-1,2-be nzoisotiazol-3-(2H)-on-1,1-dióxido ou um sal fisiologicamente aceitável do mesmo.
BR0212199-9A 2001-09-12 2002-08-09 Uso de aminometil cromanos substituìdos no tratamento de distúrbios do movimento BR0212199A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01121910 2001-09-12
PCT/EP2002/008912 WO2003022269A1 (en) 2001-09-12 2002-08-09 Novel use of substituted aminomethyl chromans for the treatment of movement disorders and of adverse effects induced by drugs administered to treat extrapyramidal movement disorders

Publications (1)

Publication Number Publication Date
BR0212199A true BR0212199A (pt) 2004-10-05

Family

ID=8178618

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212199-9A BR0212199A (pt) 2001-09-12 2002-08-09 Uso de aminometil cromanos substituìdos no tratamento de distúrbios do movimento

Country Status (23)

Country Link
US (1) US20040235920A1 (pt)
EP (1) EP1425008B1 (pt)
JP (1) JP2005522410A (pt)
KR (1) KR100886185B1 (pt)
CN (1) CN1303996C (pt)
AR (1) AR036509A1 (pt)
AT (1) ATE341322T1 (pt)
AU (1) AU2002331220B2 (pt)
BR (1) BR0212199A (pt)
CA (1) CA2458628A1 (pt)
CY (1) CY1105868T1 (pt)
DE (1) DE60215203T2 (pt)
DK (1) DK1425008T3 (pt)
ES (1) ES2272771T3 (pt)
HU (1) HUP0401317A3 (pt)
MX (1) MXPA04002304A (pt)
MY (1) MY130522A (pt)
PL (1) PL207146B1 (pt)
PT (1) PT1425008E (pt)
RU (1) RU2320336C2 (pt)
SI (1) SI1425008T1 (pt)
WO (1) WO2003022269A1 (pt)
ZA (1) ZA200402774B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004012659A2 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
CN103402514B (zh) * 2010-10-15 2016-01-13 康特拉医药公司 用于治疗运动障碍的血清素受体激动剂组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
SE9303274D0 (sv) * 1993-10-07 1993-10-07 Astra Ab Novel phenylethyl and phenylproplamines
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen

Also Published As

Publication number Publication date
KR20040043175A (ko) 2004-05-22
PL369827A1 (en) 2005-05-02
US20040235920A1 (en) 2004-11-25
PT1425008E (pt) 2007-01-31
JP2005522410A (ja) 2005-07-28
WO2003022269A1 (en) 2003-03-20
RU2004111284A (ru) 2005-05-10
AU2002331220B2 (en) 2007-06-07
AR036509A1 (es) 2004-09-15
PL207146B1 (pl) 2010-11-30
CY1105868T1 (el) 2011-02-02
DK1425008T3 (da) 2007-01-15
MY130522A (en) 2007-06-29
KR100886185B1 (ko) 2009-02-27
CN1555259A (zh) 2004-12-15
RU2320336C2 (ru) 2008-03-27
MXPA04002304A (es) 2004-06-29
CN1303996C (zh) 2007-03-14
ATE341322T1 (de) 2006-10-15
ES2272771T3 (es) 2007-05-01
ZA200402774B (en) 2005-01-13
DE60215203D1 (de) 2006-11-16
HUP0401317A2 (en) 2004-10-28
DE60215203T2 (de) 2007-10-18
EP1425008A1 (en) 2004-06-09
EP1425008B1 (en) 2006-10-04
HUP0401317A3 (en) 2007-05-29
CA2458628A1 (en) 2003-03-20
SI1425008T1 (sl) 2007-02-28

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 31/15, A61K 31/195, A61K 31/353, A61K 31/425, A61K 31/428, A61P 25/00, A61P 25/14, A61P 25/16, A61P 25/18, C07D 417/12

Ipc: A61K 31/15 (2006.01), A61K 31/195 (2006.01), A61K

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2162 DE 12/06/2012.